SI2148697T1 - Liofilizirani sestavek, ki vsebuje CpG in WT-1 - Google Patents
Liofilizirani sestavek, ki vsebuje CpG in WT-1Info
- Publication number
- SI2148697T1 SI2148697T1 SI200830836T SI200830836T SI2148697T1 SI 2148697 T1 SI2148697 T1 SI 2148697T1 SI 200830836 T SI200830836 T SI 200830836T SI 200830836 T SI200830836 T SI 200830836T SI 2148697 T1 SI2148697 T1 SI 2148697T1
- Authority
- SI
- Slovenia
- Prior art keywords
- lyophilised
- composition
- cpg containing
- cpg
- lyophilised cpg
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001152—Transcription factors, e.g. SOX or c-MYC
- A61K39/001153—Wilms tumor 1 [WT1]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/17—Immunomodulatory nucleic acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2007/055037 WO2007137986A2 (en) | 2006-05-26 | 2007-05-24 | Vaccination against cancer |
GB0723044A GB0723044D0 (en) | 2007-11-23 | 2007-11-23 | Lyophillised antigen composition |
GB0723900A GB0723900D0 (en) | 2007-12-06 | 2007-12-06 | Lyophillised antigen composition |
PCT/EP2008/056305 WO2008142133A1 (en) | 2007-05-24 | 2008-05-22 | Lyophilised antigen composition |
EP08759906A EP2148697B1 (en) | 2007-05-24 | 2008-05-22 | Lyophilised cpg containing wt-1 composition |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2148697T1 true SI2148697T1 (sl) | 2013-01-31 |
Family
ID=39714209
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200830836T SI2148697T1 (sl) | 2007-05-24 | 2008-05-22 | Liofilizirani sestavek, ki vsebuje CpG in WT-1 |
Country Status (23)
Country | Link |
---|---|
US (2) | US20090035360A1 (sl) |
EP (3) | EP2148697B1 (sl) |
JP (1) | JP5331105B2 (sl) |
KR (2) | KR101238795B1 (sl) |
CN (1) | CN101678091A (sl) |
AR (1) | AR066676A1 (sl) |
AU (1) | AU2008252911B2 (sl) |
BR (1) | BRPI0811228A2 (sl) |
CA (1) | CA2687632C (sl) |
CL (1) | CL2008001491A1 (sl) |
CY (1) | CY1113446T1 (sl) |
DK (1) | DK2148697T3 (sl) |
EA (3) | EA201300101A1 (sl) |
ES (1) | ES2395333T3 (sl) |
HR (1) | HRP20121019T1 (sl) |
MX (1) | MX2009012381A (sl) |
PE (1) | PE20090281A1 (sl) |
PL (1) | PL2148697T3 (sl) |
PT (1) | PT2148697E (sl) |
SI (1) | SI2148697T1 (sl) |
TW (1) | TW200911304A (sl) |
UY (1) | UY31101A1 (sl) |
WO (1) | WO2008142133A1 (sl) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200726479A (en) | 2005-04-12 | 2007-07-16 | Univ Duke | Method of inducing neutralizing antibodies to human immunodeficiency virus |
JP2009511637A (ja) | 2005-10-17 | 2009-03-19 | スローン−ケターリング インスティチュート フォー キャンサー リサーチ | Hlaクラスii結合wt1ペプチド及びその組成物、並びにその作成方法 |
CA2645766A1 (en) | 2006-04-10 | 2007-10-25 | Sloan Kettering Institute For Cancer Research | Immunogenic wt-1 peptides and methods of use thereof |
WO2008127651A1 (en) * | 2007-04-13 | 2008-10-23 | Duke University | Method of inducing neutralizing antibodies to human immunodeficiency virus |
CA2757240A1 (en) * | 2009-04-03 | 2010-10-07 | Duke University | Formulation for inducing broadly reactive neutralizing anti-hiv antibodies |
GB0910045D0 (en) * | 2009-06-10 | 2009-07-22 | Glaxosmithkline Biolog Sa | Novel compositions |
GB0910046D0 (en) * | 2009-06-10 | 2009-07-22 | Glaxosmithkline Biolog Sa | Novel compositions |
CN103260642B (zh) * | 2010-12-14 | 2018-03-16 | 葛兰素史密丝克莱恩生物有限公司 | 分枝杆菌抗原组合物 |
JP2014529338A (ja) * | 2011-07-22 | 2014-11-06 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | Prameの精製 |
CN108676069A (zh) | 2012-01-13 | 2018-10-19 | 纪念斯隆凯特林癌症中心 | 免疫原性wt-1肽及其使用方法 |
US10815273B2 (en) | 2013-01-15 | 2020-10-27 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
CN110078813B (zh) | 2013-01-15 | 2023-03-28 | 纪念斯隆凯特林癌症中心 | 免疫原性wt-1肽和其使用方法 |
US10076567B2 (en) | 2013-09-27 | 2018-09-18 | Duke University | MPER-liposome conjugates and uses thereof |
KR102411781B1 (ko) * | 2013-12-31 | 2022-06-22 | 인펙셔스 디지즈 리서치 인스티튜트 (아이디알아이) | 단일 바이알 백신 제형 |
RU2016141621A (ru) * | 2014-03-25 | 2018-04-25 | Зэ Гавермент Оф Зэ Юнайтед Стэйтс Оф Америка Эс Репрезентед Бай Зэ Секретари Оф Зэ Арми | Способы усиления эффективности иммуностимуляции адсорбированных на соли алюминия вакцин |
SG11201803594TA (en) | 2015-11-06 | 2018-05-30 | Adjuvance Technologies Inc | Triterpene saponin analogues |
WO2018104313A1 (en) | 2016-12-07 | 2018-06-14 | Glaxosmithkline Biologicals Sa | Novel process |
CA3075822A1 (en) * | 2017-10-16 | 2019-04-25 | Adjuvance Technologies, Inc. | Triterpene saponin analogues |
CN112673054A (zh) | 2018-07-19 | 2021-04-16 | 葛兰素史密丝克莱恩生物有限公司 | 用于制备干燥多糖的方法 |
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US666A (en) | 1838-04-02 | Sfbing-bock for coagh and railroad-gab | ||
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US6222020B1 (en) | 1987-01-07 | 2001-04-24 | Imperial Cancer Research Technology Limited | Antigens derived from the core protein of the human mammary epithelial mucin |
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US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
US4963484A (en) | 1988-01-29 | 1990-10-16 | Dana-Farber Cancer Institute, Inc. | Genetically engineered polypeptides with determinants of the human DF3 breast carcinoma-associated antigen |
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JP2001517638A (ja) * | 1997-09-25 | 2001-10-09 | スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ | 小細胞肺癌に対するフコーシルgm−1−klh接合体ワクチン |
GB9727262D0 (en) | 1997-12-24 | 1998-02-25 | Smithkline Beecham Biolog | Vaccine |
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US20030235557A1 (en) * | 1998-09-30 | 2003-12-25 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
ES2348708T3 (es) | 1999-01-29 | 2010-12-13 | Corixa Corporation | Proteinas de fusion de her-2/neu. |
AU756398B2 (en) | 1999-03-11 | 2003-01-09 | Smithkline Beecham Biologicals (Sa) | Novel compounds |
US6949520B1 (en) * | 1999-09-27 | 2005-09-27 | Coley Pharmaceutical Group, Inc. | Methods related to immunostimulatory nucleic acid-induced interferon |
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US20040022814A1 (en) * | 2000-06-15 | 2004-02-05 | O'hagan Derek | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
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GB0323968D0 (en) | 2003-10-13 | 2003-11-19 | Glaxosmithkline Biolog Sa | Immunogenic compositions |
EP1547581A1 (en) * | 2003-12-23 | 2005-06-29 | Vectron Therapeutics AG | Liposomal vaccine for the treatment of human hematological malignancies |
GB0409940D0 (en) * | 2004-05-04 | 2004-06-09 | Glaxosmithkline Biolog Sa | Vaccine |
GB0411411D0 (en) | 2004-05-21 | 2004-06-23 | Glaxosmithkline Biolog Sa | Vaccines |
EA200700017A1 (ru) * | 2004-06-12 | 2009-06-30 | Ле Сантр Насьональ Де Ля Решерш Сьентифик ( Снрс ) | Способ усиления иммунного ответа на вакцину |
GB0417494D0 (en) | 2004-08-05 | 2004-09-08 | Glaxosmithkline Biolog Sa | Vaccine |
EP1858526A1 (en) | 2005-03-02 | 2007-11-28 | Solbec Pharmaceuticals Limited | Glycoalkaloid and tlr agonist combinations and various uses thereof |
SG162817A1 (en) * | 2005-06-17 | 2010-07-29 | Mannkind Corp | Methods and compositions.to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma |
-
2008
- 2008-05-22 PT PT87599064T patent/PT2148697E/pt unknown
- 2008-05-22 TW TW097119008A patent/TW200911304A/zh unknown
- 2008-05-22 EP EP08759906A patent/EP2148697B1/en not_active Not-in-force
- 2008-05-22 EP EP20120157797 patent/EP2489367A1/en not_active Withdrawn
- 2008-05-22 EA EA201300101A patent/EA201300101A1/ru unknown
- 2008-05-22 CN CN200880017245A patent/CN101678091A/zh active Pending
- 2008-05-22 KR KR1020097025005A patent/KR101238795B1/ko not_active IP Right Cessation
- 2008-05-22 EA EA200901434A patent/EA018201B1/ru not_active IP Right Cessation
- 2008-05-22 PL PL08759906T patent/PL2148697T3/pl unknown
- 2008-05-22 UY UY31101A patent/UY31101A1/es unknown
- 2008-05-22 CA CA2687632A patent/CA2687632C/en not_active Expired - Fee Related
- 2008-05-22 KR KR1020117016237A patent/KR20110091817A/ko not_active Application Discontinuation
- 2008-05-22 EP EP12157796A patent/EP2476431A1/en not_active Withdrawn
- 2008-05-22 MX MX2009012381A patent/MX2009012381A/es active IP Right Grant
- 2008-05-22 JP JP2010508850A patent/JP5331105B2/ja not_active Expired - Fee Related
- 2008-05-22 CL CL2008001491A patent/CL2008001491A1/es unknown
- 2008-05-22 AR ARP080102167A patent/AR066676A1/es not_active Application Discontinuation
- 2008-05-22 DK DK08759906.4T patent/DK2148697T3/da active
- 2008-05-22 SI SI200830836T patent/SI2148697T1/sl unknown
- 2008-05-22 AU AU2008252911A patent/AU2008252911B2/en not_active Ceased
- 2008-05-22 ES ES08759906T patent/ES2395333T3/es active Active
- 2008-05-22 WO PCT/EP2008/056305 patent/WO2008142133A1/en active Application Filing
- 2008-05-22 EA EA201300102A patent/EA201300102A1/ru unknown
- 2008-05-22 BR BRPI0811228-2A2A patent/BRPI0811228A2/pt not_active IP Right Cessation
- 2008-05-22 PE PE2008000879A patent/PE20090281A1/es not_active Application Discontinuation
- 2008-05-22 US US12/125,182 patent/US20090035360A1/en not_active Abandoned
-
2010
- 2010-11-15 US US12/946,171 patent/US8557247B2/en not_active Expired - Fee Related
-
2012
- 2012-12-10 CY CY20121101196T patent/CY1113446T1/el unknown
- 2012-12-12 HR HRP20121019AT patent/HRP20121019T1/hr unknown
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