IL140155A - Process for producing immunoglobulins for intravenous administration and other immunoglobulin products - Google Patents

Process for producing immunoglobulins for intravenous administration and other immunoglobulin products

Info

Publication number
IL140155A
IL140155A IL14015599A IL14015599A IL140155A IL 140155 A IL140155 A IL 140155A IL 14015599 A IL14015599 A IL 14015599A IL 14015599 A IL14015599 A IL 14015599A IL 140155 A IL140155 A IL 140155A
Authority
IL
Israel
Prior art keywords
immunoglobulin
product
intravenous administration
iga
exchange chromatography
Prior art date
Application number
IL14015599A
Other languages
English (en)
Other versions
IL140155A0 (en
Original Assignee
Statens Seruminstitut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26150417&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL140155(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Statens Seruminstitut filed Critical Statens Seruminstitut
Publication of IL140155A0 publication Critical patent/IL140155A0/xx
Publication of IL140155A publication Critical patent/IL140155A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14015599A 1998-06-09 1999-06-09 Process for producing immunoglobulins for intravenous administration and other immunoglobulin products IL140155A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98201909 1998-06-09
US10205598P 1998-09-28 1998-09-28
PCT/DK1999/000312 WO1999064462A1 (en) 1998-06-09 1999-06-09 Process for producing immunoglobulins for intravenous administration and other immunoglobulin products

Publications (2)

Publication Number Publication Date
IL140155A0 IL140155A0 (en) 2002-02-10
IL140155A true IL140155A (en) 2005-12-18

Family

ID=26150417

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14015599A IL140155A (en) 1998-06-09 1999-06-09 Process for producing immunoglobulins for intravenous administration and other immunoglobulin products

Country Status (22)

Country Link
EP (4) EP2270044B1 (pl)
JP (1) JP5478519B2 (pl)
KR (1) KR100501263B1 (pl)
CN (1) CN1196714C (pl)
AT (1) ATE277950T1 (pl)
AU (1) AU753468B2 (pl)
BR (1) BR9911131A (pl)
CA (1) CA2330170C (pl)
CZ (1) CZ297199B6 (pl)
DE (1) DE69920693T2 (pl)
DK (1) DK1084147T3 (pl)
ES (1) ES2229784T3 (pl)
HU (1) HU228076B1 (pl)
ID (1) ID27417A (pl)
IL (1) IL140155A (pl)
NZ (1) NZ509135A (pl)
PL (1) PL196770B1 (pl)
PT (1) PT1084147E (pl)
RU (1) RU2197500C2 (pl)
SK (1) SK288128B6 (pl)
TR (1) TR200100303T2 (pl)
WO (1) WO1999064462A1 (pl)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
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ES2184594B1 (es) * 2001-01-17 2004-01-01 Probitas Pharma Sa Procedimiento para la produccion de gammaglobulina g humana inactivada de virus.
FR2824568B1 (fr) 2001-05-11 2004-04-09 Lab Francais Du Fractionnement Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique
US20030223985A1 (en) * 2002-05-29 2003-12-04 The Lauridsen Group. Incorporated Globulin protein to lower cholesterol in humans
WO2004024752A1 (ja) 2002-09-11 2004-03-25 Chugai Seiyaku Kabushiki Kaisha タンパク質精製方法
EP1614693A4 (en) * 2003-03-31 2006-07-19 Kirin Brewery Purification of a human monoclonal antibody and human polyclonal antibody
EP1532983A1 (en) 2003-11-18 2005-05-25 ZLB Bioplasma AG Immunoglobulin preparations having increased stability
KR20070009995A (ko) * 2004-01-30 2007-01-19 수오멘 푸나이넨 리스티 베리팔베루 바이러스 안전성 면역글로불린을 제조하는 방법
NZ576986A (en) 2004-01-30 2010-12-24 Shire Pharmaceuticals Ireland Ltd Production and purification of recombinant arylsulfatase A
RU2252780C1 (ru) * 2004-04-30 2005-05-27 Аваков Анатолий Эдуардович Способ получения иммуноглобулинового препарата
AU2005229674B2 (en) * 2004-11-18 2010-11-04 Kedrion Melville Inc. Low concentration solvent/detergent process of immuneglobulin with pre-treatment
TWI391399B (zh) 2005-05-25 2013-04-01 Hoffmann La Roche 測定溶離多肽之鹽濃度之方法
CA2623429C (en) 2005-09-30 2015-01-13 Medimmune Limited Interleukin-13 antibody composition
US9309316B2 (en) 2005-12-20 2016-04-12 Bristol-Myers Squibb Company Stable subcutaneous protein formulations and uses thereof
FR2895263B1 (fr) 2005-12-26 2008-05-30 Lab Francais Du Fractionnement Concentre d'immunoglobines g (lg) appauvri en anticorps anti-a et anti-b, et en igg polyreactives
NZ582045A (en) * 2006-04-04 2011-07-29 Zymenex As A pharmaceutical composition comprising at least 10mg/mL of alfa mannosidase and less that 5% total protein aggregates
RU2303995C1 (ru) * 2006-04-28 2007-08-10 Халлар Абдумуслимович Алиханов Средство, обладающее иммунорегуляторным свойством и его применение для лечения аутоиммунных заболеваний
PL2061803T5 (pl) 2006-08-28 2023-03-27 Ares Trading S.A. Proces oczyszczania białek zawierających fc
DE102007001521A1 (de) * 2007-01-10 2008-07-17 Matthias, Torsten, Dr. Verwendung von Cohn-Oncley-Fraktionen II und II/III zur Behandlung des systemischen Lupus erythematodes
UA85734C2 (ru) * 2007-02-14 2009-02-25 Костянтин Васильевич Курищук Способ инактивации вирусов при получении иммуноглобулина
UA85741C2 (ru) * 2007-02-27 2009-02-25 Костянтин Васильевич Курищук Способ получения иммуноглобулина
RU2352358C1 (ru) * 2007-10-04 2009-04-20 Наталия Васильевна Зубкова Способ приготовления вирусинактивированных растворов иммуноглобулинов
BRPI0817182A2 (pt) 2007-10-30 2015-03-17 Genentech Inc Método para purificar um anticorpo e composições
US8883146B2 (en) 2007-11-30 2014-11-11 Abbvie Inc. Protein formulations and methods of making same
ES2406029T3 (es) 2008-04-15 2013-06-05 Grifols Therapeutics Inc. Ultrafiltración/diafiltración en dos fases
RU2410395C2 (ru) * 2008-05-04 2011-01-27 Институт биохимии и физиологии растений и микроорганизмов Российской Академии наук Способ получения моноспецифических антител к белкам растительных клеток
FR2939667B1 (fr) 2008-12-17 2012-01-27 Fractionnement Et Des Biotechonologies Lab Franc Composition d'immunoglobine g comme medicament pour le traitement de l'ictere neonatal par incompatibilite foetomaternelle dans le systeme abo
MY157239A (en) 2009-05-27 2016-05-13 Baxalta Inc A method to produce a highly concentrated immunoglobulin preparation for subcutaneous use
US20130116413A1 (en) * 2009-12-29 2013-05-09 Dr. Reddy's Laboratories, Inc. Purification of proteins
TR201903403T4 (tr) 2010-02-04 2019-04-22 Csl Behring Ag İmmünoglobulin preparatı.
EP2361636A1 (en) * 2010-02-26 2011-08-31 CSL Behring AG Immunoglobulin preparation and storage system for an immunoglobulin preparation
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RU2467783C2 (ru) * 2010-07-30 2012-11-27 Закрытое акционерное общество "БиоХимМак СТ" Способ хроматографического выделения иммуноглобулина
WO2012090067A1 (en) 2010-12-30 2012-07-05 Lfb Biotechnologies Glycols as pathogen inactivating agents
ES2865449T3 (es) 2011-03-16 2021-10-15 Hoffmann La Roche Cromatografía de intercambio iónico con selectividad mejorada para la separación de monómeros, agregados y fragmentos polipeptídicos por modulación de la fase móvil
FR2974301B1 (fr) 2011-04-20 2013-08-23 Lab Francais Du Fractionnement Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes
IL212911A0 (en) * 2011-05-16 2011-07-31 Omrix Biopharmaceuticals Ltd Immunoglobulin reduced in thrombogenic contaminants and preparation thereof
ES2625511T3 (es) 2011-07-08 2017-07-19 Shire Human Genetic Therapies, Inc. Métodos para la purificación de arylsulfatasa A
SG11201400233TA (en) * 2011-08-26 2014-08-28 Baxter Int Method for reducing the thromboembolic potential of a plasma-derived immunoglobulin composition
CN102532307B (zh) * 2012-02-22 2013-06-12 成都蓉生药业有限责任公司 一种制备人免疫球蛋白的方法
ES2943585T3 (es) 2012-02-29 2023-06-14 Takeda Pharmaceuticals Co Remielinización estimulada por IgG de nervios periféricos
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EP2822967B1 (en) 2012-03-09 2019-08-07 CSL Behring AG Compositions comprising secretory-like immunoglobulins
ES2381828B1 (es) * 2012-03-20 2012-11-16 Grifols, S.A. PROCEDIMIENTO PARA OBTENER UNA COMPOSICION DE IgG MEDIANTE TRATAMIENTO TERMICO
WO2013180648A1 (en) 2012-05-31 2013-12-05 Agency For Science, Technology And Research Methods for use of mixed multifunctional surfaces for reducing aggregate content in protein preparations
KR20150027060A (ko) * 2012-05-31 2015-03-11 에이전시 포 사이언스, 테크놀로지 앤드 리서치 다중 모드의 기능성들을 갖는 입자들로 면역글로불린 g 조제물들의 크로마토그래피 정제
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
CN104903442A (zh) 2013-01-09 2015-09-09 夏尔人类遗传性治疗公司 含用于纯化芳基硫酸酯酶a的方法
AU2013203043B2 (en) 2013-03-15 2016-10-06 Takeda Pharmaceutical Company Limited Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
US10464996B2 (en) 2013-05-13 2019-11-05 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
ES2833100T3 (es) 2013-07-01 2021-06-14 Csl Behring Ag Procedimiento
ES2793176T3 (es) 2013-07-05 2020-11-13 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Sa Matriz de cromografía de afinidad
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CN103665100A (zh) * 2014-01-03 2014-03-26 华兰生物工程重庆有限公司 低温乙醇提取静注人免疫球蛋白的方法
ES2785375T3 (es) 2014-03-11 2020-10-06 Green Cross Holdings Corp Procedimiento de purificación de inmunoglobulina
FR3018450B1 (fr) * 2014-03-11 2016-04-15 Lab Francais Du Fractionnement Procede de preparation de proteines plasmatiques humaines
WO2015158776A1 (en) * 2014-04-15 2015-10-22 Boehringer Ingelheim International Gmbh Methods, apparatuses, and systems for continuously inactivating a virus during manufacture of a biological product
CN104004090A (zh) * 2014-06-12 2014-08-27 新疆德源生物工程有限公司 一种人免疫球蛋白的制备方法
CN104356231B (zh) * 2014-11-10 2017-08-08 北海开元生物科技有限公司 一种有效去除人免疫球蛋白多聚体的方法
US9556253B2 (en) 2014-12-02 2017-01-31 Hemarus Therapeutics Limited Process for increased yield of immunoglobulin from human plasma
US12144861B2 (en) 2014-12-03 2024-11-19 Csl Behring Ag Pharmaceutical product with increased stability comprising immunoglobulins
FR3035971A1 (fr) 2015-05-07 2016-11-11 Lab Francais Du Fractionnement Composition enrichie en immunoglobulines polyclonales anti-a et/ou anti-b
KR101657690B1 (ko) * 2015-06-05 2016-09-19 주식회사 녹십자홀딩스 혈장 유래 b형 간염 사람 면역글로불린 제제의 제조방법
CN105950576A (zh) * 2016-05-26 2016-09-21 成都远睿生物技术有限公司 一种从牛血中提取多种蛋白的方法
EP3275897A1 (en) * 2016-07-27 2018-01-31 Biotest AG Process for preparing immunoglobulin compositions
CN107880116B (zh) * 2016-09-30 2023-02-03 盖立复集团公司 用于制备免疫球蛋白的方法
FR3064484A1 (fr) 2017-03-31 2018-10-05 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Composition d'immunoglobulines utiles pour traiter des infections virales
FR3064486A1 (fr) 2017-03-31 2018-10-05 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Prevention d'une infection par le virus respiratoire syncytial dans les voies respiratoires superieures
FR3064485A1 (fr) 2017-03-31 2018-10-05 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Traitement d'une infection par le virus respiratoire syncytial
KR20190047376A (ko) 2017-10-27 2019-05-08 주식회사 녹십자 개선된 면역글로불린의 정제방법
CN109776675A (zh) * 2017-11-10 2019-05-21 北京博莱得利生物技术有限责任公司 两步离子交换层析法制备犬免疫球蛋白的方法
CN112574296B (zh) * 2020-12-30 2023-05-19 中国医学科学院输血研究所 一种模拟IVIg的多人份混合人血浆IgG样品的分离纯化方法
KR20230148961A (ko) * 2022-04-19 2023-10-26 에스케이플라즈마 주식회사 면역글로불린 정제방법

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
DE2364792A1 (de) * 1973-01-15 1974-07-18 South African Inventions Verfahren zum reinigen von gammaglobulin
US4296027A (en) * 1977-08-31 1981-10-20 The Regents Of The University Of Minnesota Pure intravenous human and animal gamma globulins
US4314997A (en) 1980-10-06 1982-02-09 Edward Shanbrom Purification of plasma protein products
US4315919A (en) 1980-10-06 1982-02-16 Edward Shanbrom Depyrogenation process
US4764369A (en) 1983-07-14 1988-08-16 New York Blood Center Inc. Undenatured virus-free biologically active protein derivatives
US4606825A (en) * 1985-04-22 1986-08-19 J. T. Baker Chemical Company Purification of immunoglobulin G
NZ216094A (en) * 1985-05-15 1989-06-28 Commw Serum Lab Commission Method for purification of an immunoglobulin
DE4118912C1 (pl) * 1991-06-08 1992-07-02 Biotest Pharma Gmbh, 6072 Dreieich, De
FR2706466B1 (fr) * 1993-06-14 1995-08-25 Aetsrn Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré.
RU2094462C1 (ru) * 1995-11-14 1997-10-27 Оловникова Наталья Ивановна Моноклональный иммуноглобулин человека класса iggi против антигена d системы резус

Also Published As

Publication number Publication date
SK18662000A3 (sk) 2001-07-10
EP2272870B1 (en) 2013-05-08
DE69920693T2 (de) 2005-11-03
PT1084147E (pt) 2005-01-31
EP1084147A1 (en) 2001-03-21
ES2229784T3 (es) 2005-04-16
EP1084147B1 (en) 2004-09-29
JP2011102314A (ja) 2011-05-26
PL344671A1 (en) 2001-11-19
WO1999064462A1 (en) 1999-12-16
EP2270044B1 (en) 2014-11-05
BR9911131A (pt) 2001-03-06
RU2001101454A (ru) 2003-01-20
CN1196714C (zh) 2005-04-13
RU2197500C2 (ru) 2003-01-27
EP1493751A1 (en) 2005-01-05
NZ509135A (en) 2002-10-25
JP5478519B2 (ja) 2014-04-23
ATE277950T1 (de) 2004-10-15
PL196770B1 (pl) 2008-01-31
AU753468B2 (en) 2002-10-17
CA2330170A1 (en) 1999-12-16
TR200100303T2 (tr) 2001-06-21
HUP0101988A3 (en) 2004-10-28
CA2330170C (en) 2010-11-02
KR20010052733A (ko) 2001-06-25
SK288128B6 (sk) 2013-10-02
HK1151044A1 (en) 2012-01-20
DE69920693D1 (de) 2004-11-04
EP2270044A1 (en) 2011-01-05
IL140155A0 (en) 2002-02-10
ID27417A (id) 2001-04-05
DK1084147T3 (da) 2004-10-25
CZ297199B6 (cs) 2006-09-13
CZ20004534A3 (en) 2001-06-13
KR100501263B1 (ko) 2005-07-18
AU4257299A (en) 1999-12-30
HK1151045A1 (en) 2012-01-20
CN1311797A (zh) 2001-09-05
EP2272870A1 (en) 2011-01-12
HUP0101988A2 (hu) 2001-09-28
HU228076B1 (en) 2012-10-29

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