IL140155A - Process for producing immunoglobulins for intravenous administration and other immunoglobulin products - Google Patents

Process for producing immunoglobulins for intravenous administration and other immunoglobulin products

Info

Publication number
IL140155A
IL140155A IL14015599A IL14015599A IL140155A IL 140155 A IL140155 A IL 140155A IL 14015599 A IL14015599 A IL 14015599A IL 14015599 A IL14015599 A IL 14015599A IL 140155 A IL140155 A IL 140155A
Authority
IL
Israel
Prior art keywords
immunoglobulin
product
intravenous administration
iga
exchange chromatography
Prior art date
Application number
IL14015599A
Other languages
English (en)
Other versions
IL140155A0 (en
Original Assignee
Statens Seruminstitut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26150417&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL140155(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Statens Seruminstitut filed Critical Statens Seruminstitut
Publication of IL140155A0 publication Critical patent/IL140155A0/xx
Publication of IL140155A publication Critical patent/IL140155A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14015599A 1998-06-09 1999-06-09 Process for producing immunoglobulins for intravenous administration and other immunoglobulin products IL140155A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98201909 1998-06-09
US10205598P 1998-09-28 1998-09-28
PCT/DK1999/000312 WO1999064462A1 (en) 1998-06-09 1999-06-09 Process for producing immunoglobulins for intravenous administration and other immunoglobulin products

Publications (2)

Publication Number Publication Date
IL140155A0 IL140155A0 (en) 2002-02-10
IL140155A true IL140155A (en) 2005-12-18

Family

ID=26150417

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14015599A IL140155A (en) 1998-06-09 1999-06-09 Process for producing immunoglobulins for intravenous administration and other immunoglobulin products

Country Status (23)

Country Link
EP (4) EP2270044B1 (hu)
JP (1) JP5478519B2 (hu)
KR (1) KR100501263B1 (hu)
CN (1) CN1196714C (hu)
AT (1) ATE277950T1 (hu)
AU (1) AU753468B2 (hu)
BR (1) BR9911131A (hu)
CA (1) CA2330170C (hu)
CZ (1) CZ297199B6 (hu)
DE (1) DE69920693T2 (hu)
DK (1) DK1084147T3 (hu)
ES (1) ES2229784T3 (hu)
HK (2) HK1151044A1 (hu)
HU (1) HU228076B1 (hu)
ID (1) ID27417A (hu)
IL (1) IL140155A (hu)
NZ (1) NZ509135A (hu)
PL (1) PL196770B1 (hu)
PT (1) PT1084147E (hu)
RU (1) RU2197500C2 (hu)
SK (1) SK288128B6 (hu)
TR (1) TR200100303T2 (hu)
WO (1) WO1999064462A1 (hu)

Families Citing this family (70)

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ES2158776B1 (es) * 1999-04-13 2002-03-16 Apc Europ S A Procedimiento para la obtencion de gammaglobulinas de origen animal y aplicaciones correspondientes.
AUPQ026799A0 (en) * 1999-05-10 1999-06-03 Csl Limited Method of increasing protein stability by removing immunoglobulin aggregates
JP2003525905A (ja) * 2000-03-10 2003-09-02 メディンノバ・エスエフ 心不全治療のための組成物
SE0001128D0 (sv) * 2000-03-30 2000-03-30 Amersham Pharm Biotech Ab A method of producing IgG
ES2184594B1 (es) * 2001-01-17 2004-01-01 Probitas Pharma Sa Procedimiento para la produccion de gammaglobulina g humana inactivada de virus.
FR2824568B1 (fr) 2001-05-11 2004-04-09 Lab Francais Du Fractionnement Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique
US20030223985A1 (en) * 2002-05-29 2003-12-04 The Lauridsen Group. Incorporated Globulin protein to lower cholesterol in humans
ES2626268T3 (es) 2002-09-11 2017-07-24 Chugai Seiyaku Kabushiki Kaisha Método de purificación de proteínas
JPWO2004087761A1 (ja) * 2003-03-31 2006-07-27 麒麟麦酒株式会社 ヒトモノクローナル抗体およびヒトポリクローナル抗体の精製
EP1532983A1 (en) 2003-11-18 2005-05-25 ZLB Bioplasma AG Immunoglobulin preparations having increased stability
JP2008500959A (ja) * 2004-01-30 2008-01-17 スオメン プナイネン リスティ ヴェリパルヴェル ウイルスについて安全な免疫グロブリンの製造方法
JP4586027B2 (ja) 2004-01-30 2010-11-24 シャイア ファーマシューティカルズ アイルランド リミテッド 組換えアリールスルファターゼａの製造及び精製
AU2005229674B2 (en) * 2004-11-18 2010-11-04 Kedrion Melville Inc. Low concentration solvent/detergent process of immuneglobulin with pre-treatment
TWI320788B (en) 2005-05-25 2010-02-21 Hoffmann La Roche Method for the purification of antibodies
CA2623429C (en) 2005-09-30 2015-01-13 Medimmune Limited Interleukin-13 antibody composition
US9309316B2 (en) 2005-12-20 2016-04-12 Bristol-Myers Squibb Company Stable subcutaneous protein formulations and uses thereof
FR2895263B1 (fr) 2005-12-26 2008-05-30 Lab Francais Du Fractionnement Concentre d'immunoglobines g (lg) appauvri en anticorps anti-a et anti-b, et en igg polyreactives
EP2628746B1 (en) * 2006-04-04 2019-01-09 Chiesi Farmaceutici S.p.A. A process for the concentration of a polypeptide
RU2303995C1 (ru) * 2006-04-28 2007-08-10 Халлар Абдумуслимович Алиханов Средство, обладающее иммунорегуляторным свойством и его применение для лечения аутоиммунных заболеваний
DK2061803T4 (da) 2006-08-28 2022-12-05 Ares Trading Sa Fremgangsmåde til oprensning af fc-holdige proteiner
DE102007001521A1 (de) * 2007-01-10 2008-07-17 Matthias, Torsten, Dr. Verwendung von Cohn-Oncley-Fraktionen II und II/III zur Behandlung des systemischen Lupus erythematodes
KR101241486B1 (ko) 2007-10-30 2013-03-15 제넨테크, 인크. 양이온 교환 크로마토그래피에 의한 항체 정제
US8883146B2 (en) 2007-11-30 2014-11-11 Abbvie Inc. Protein formulations and methods of making same
CA2721037C (en) 2008-04-15 2018-05-22 Talecris Biotherapeutics, Inc. Methods for preparing a concentrated plasma product formulation using ultrafiltration/diafiltration
FR2939667B1 (fr) 2008-12-17 2012-01-27 Fractionnement Et Des Biotechonologies Lab Franc Composition d'immunoglobine g comme medicament pour le traitement de l'ictere neonatal par incompatibilite foetomaternelle dans le systeme abo
TWI445714B (zh) * 2009-05-27 2014-07-21 Baxter Int 產製用於皮下使用之高濃度免疫球蛋白製備物之方法
EP2519537A4 (en) * 2009-12-29 2013-07-10 Reddys Lab Ltd Dr CLEANING PROTEINS
WO2011095543A1 (en) 2010-02-04 2011-08-11 Csl Behring Ag Immunoglobulin preparation
EP2361636A1 (en) * 2010-02-26 2011-08-31 CSL Behring AG Immunoglobulin preparation and storage system for an immunoglobulin preparation
GB201006753D0 (en) * 2010-04-22 2010-06-09 Biotest Ag Process for preparing an immunolobulin composition
RU2467783C2 (ru) * 2010-07-30 2012-11-27 Закрытое акционерное общество "БиоХимМак СТ" Способ хроматографического выделения иммуноглобулина
CA2823005C (en) 2010-12-30 2019-07-09 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Glycols as pathogen inactivating agents
EP3318571B1 (en) 2011-03-16 2021-02-17 F. Hoffmann-La Roche AG Ion exchange chromatography with improved selectivity for the separation of polypeptide monomers, aggregates and fragments by modulation of the mobile phase
FR2974301B1 (fr) 2011-04-20 2013-08-23 Lab Francais Du Fractionnement Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes
IL212911A0 (en) 2011-05-16 2011-07-31 Omrix Biopharmaceuticals Ltd Immunoglobulin reduced in thrombogenic contaminants and preparation thereof
WO2013009686A2 (en) 2011-07-08 2013-01-17 Shire Human Genetic Therapies, Inc. Methods for purification of arylsulfatase a
MY165164A (en) * 2011-08-26 2018-02-28 Baxalta Inc Method for reducing the thromboembolic potential of a plasma-derived immunoglobulin composition
CN102532307B (zh) * 2012-02-22 2013-06-12 成都蓉生药业有限责任公司 一种制备人免疫球蛋白的方法
DK2820042T3 (da) 2012-02-29 2019-10-28 Baxalta GmbH Igg-stimuleret remyelinisering af perifere nerver
EP2636681A1 (en) 2012-03-09 2013-09-11 CSL Behring AG Process for enriching IgA
NZ629072A (en) 2012-03-09 2016-03-31 Csl Behring Ag Compositions comprising secretory - like immunoglobulins
EP2636684A1 (en) 2012-03-09 2013-09-11 CSL Behring AG Prevention of infection
ES2381828B1 (es) * 2012-03-20 2012-11-16 Grifols, S.A. PROCEDIMIENTO PARA OBTENER UNA COMPOSICION DE IgG MEDIANTE TRATAMIENTO TERMICO
CN104487446B (zh) 2012-05-31 2018-05-29 新加坡科技研究局 利用混合的多官能性表面降低蛋白制剂中聚集物含量的方法
CN104507955A (zh) * 2012-05-31 2015-04-08 新加坡科技研究局 采用具有多形式官能性的颗粒对免疫球蛋白g制备物的色谱纯化
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
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AU2013203043B2 (en) * 2013-03-15 2016-10-06 Takeda Pharmaceutical Company Limited Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
WO2014186310A1 (en) 2013-05-13 2014-11-20 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
CN105358571B (zh) 2013-07-01 2019-03-05 瑞士杰特贝林生物制品有限公司 方法
EP3016729B1 (fr) 2013-07-05 2020-03-25 Laboratoire Francais du Fractionnement et des Biotechnologies Societe Anonyme Matrice de chromatographie d'affinité
US20160257754A1 (en) 2013-10-16 2016-09-08 Momenta Pharmaceuticals Inc. Sialylated glycoproteins
CN103665100A (zh) * 2014-01-03 2014-03-26 华兰生物工程重庆有限公司 低温乙醇提取静注人免疫球蛋白的方法
WO2015137530A1 (ko) * 2014-03-11 2015-09-17 주식회사 녹십자홀딩스 면역글로불린의 정제방법
FR3018450B1 (fr) 2014-03-11 2016-04-15 Lab Francais Du Fractionnement Procede de preparation de proteines plasmatiques humaines
EP4234569A3 (en) * 2014-04-15 2023-10-18 Boehringer Ingelheim International GmbH Method and use for continuously inactivating a virus during manufacture of a biological product
CN104004090A (zh) * 2014-06-12 2014-08-27 新疆德源生物工程有限公司 一种人免疫球蛋白的制备方法
CN104356231B (zh) * 2014-11-10 2017-08-08 北海开元生物科技有限公司 一种有效去除人免疫球蛋白多聚体的方法
US9556253B2 (en) 2014-12-02 2017-01-31 Hemarus Therapeutics Limited Process for increased yield of immunoglobulin from human plasma
FR3035971A1 (fr) 2015-05-07 2016-11-11 Lab Francais Du Fractionnement Composition enrichie en immunoglobulines polyclonales anti-a et/ou anti-b
KR101657690B1 (ko) 2015-06-05 2016-09-19 주식회사 녹십자홀딩스 혈장 유래 b형 간염 사람 면역글로불린 제제의 제조방법
CN105950576A (zh) * 2016-05-26 2016-09-21 成都远睿生物技术有限公司 一种从牛血中提取多种蛋白的方法
CN107880116B (zh) * 2016-09-30 2023-02-03 盖立复集团公司 用于制备免疫球蛋白的方法
FR3064485A1 (fr) 2017-03-31 2018-10-05 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Traitement d'une infection par le virus respiratoire syncytial
FR3064486A1 (fr) 2017-03-31 2018-10-05 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Prevention d'une infection par le virus respiratoire syncytial dans les voies respiratoires superieures
FR3064484A1 (fr) 2017-03-31 2018-10-05 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Composition d'immunoglobulines utiles pour traiter des infections virales
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CN112574296B (zh) * 2020-12-30 2023-05-19 中国医学科学院输血研究所 一种模拟IVIg的多人份混合人血浆IgG样品的分离纯化方法
KR20230148961A (ko) * 2022-04-19 2023-10-26 에스케이플라즈마 주식회사 면역글로불린 정제방법

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DE2364792A1 (de) * 1973-01-15 1974-07-18 South African Inventions Verfahren zum reinigen von gammaglobulin
US4296027A (en) * 1977-08-31 1981-10-20 The Regents Of The University Of Minnesota Pure intravenous human and animal gamma globulins
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US4314997A (en) 1980-10-06 1982-02-09 Edward Shanbrom Purification of plasma protein products
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NZ216094A (en) * 1985-05-15 1989-06-28 Commw Serum Lab Commission Method for purification of an immunoglobulin
DE4118912C1 (hu) * 1991-06-08 1992-07-02 Biotest Pharma Gmbh, 6072 Dreieich, De
FR2706466B1 (fr) * 1993-06-14 1995-08-25 Aetsrn Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré.

Also Published As

Publication number Publication date
EP1084147A1 (en) 2001-03-21
RU2197500C2 (ru) 2003-01-27
WO1999064462A1 (en) 1999-12-16
HU228076B1 (en) 2012-10-29
SK18662000A3 (sk) 2001-07-10
HUP0101988A3 (en) 2004-10-28
EP1084147B1 (en) 2004-09-29
EP2270044B1 (en) 2014-11-05
IL140155A0 (en) 2002-02-10
EP2270044A1 (en) 2011-01-05
SK288128B6 (sk) 2013-10-02
CN1196714C (zh) 2005-04-13
JP5478519B2 (ja) 2014-04-23
KR100501263B1 (ko) 2005-07-18
KR20010052733A (ko) 2001-06-25
CZ20004534A3 (en) 2001-06-13
HK1151045A1 (en) 2012-01-20
CA2330170A1 (en) 1999-12-16
DE69920693T2 (de) 2005-11-03
JP2011102314A (ja) 2011-05-26
CN1311797A (zh) 2001-09-05
HK1151044A1 (en) 2012-01-20
TR200100303T2 (tr) 2001-06-21
ID27417A (id) 2001-04-05
PL196770B1 (pl) 2008-01-31
PL344671A1 (en) 2001-11-19
CA2330170C (en) 2010-11-02
RU2001101454A (ru) 2003-01-20
NZ509135A (en) 2002-10-25
BR9911131A (pt) 2001-03-06
AU4257299A (en) 1999-12-30
DK1084147T3 (da) 2004-10-25
ATE277950T1 (de) 2004-10-15
HUP0101988A2 (hu) 2001-09-28
EP2272870A1 (en) 2011-01-12
ES2229784T3 (es) 2005-04-16
DE69920693D1 (de) 2004-11-04
EP1493751A1 (en) 2005-01-05
CZ297199B6 (cs) 2006-09-13
AU753468B2 (en) 2002-10-17
EP2272870B1 (en) 2013-05-08
PT1084147E (pt) 2005-01-31

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