DK2820042T3 - Igg-stimuleret remyelinisering af perifere nerver - Google Patents

Igg-stimuleret remyelinisering af perifere nerver Download PDF

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Publication number
DK2820042T3
DK2820042T3 DK13709675T DK13709675T DK2820042T3 DK 2820042 T3 DK2820042 T3 DK 2820042T3 DK 13709675 T DK13709675 T DK 13709675T DK 13709675 T DK13709675 T DK 13709675T DK 2820042 T3 DK2820042 T3 DK 2820042T3
Authority
DK
Denmark
Prior art keywords
remyelinization
igg
stimulated
peripheral nerves
nerves
Prior art date
Application number
DK13709675T
Other languages
English (en)
Inventor
Patrick Kuery
Nevena Tzekova
Hans-Peter Hartung
Birgit Maria Reipert
Hans-Peter Schwarz
Hartmut Ehrlich
Sebastian Bunk
Corinna Hermann
Original Assignee
Baxalta GmbH
Baxalta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxalta GmbH, Baxalta Inc filed Critical Baxalta GmbH
Application granted granted Critical
Publication of DK2820042T3 publication Critical patent/DK2820042T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39516Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum from serum, plasma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
DK13709675T 2012-02-29 2013-02-28 Igg-stimuleret remyelinisering af perifere nerver DK2820042T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261605117P 2012-02-29 2012-02-29
PCT/US2013/028350 WO2013130826A2 (en) 2012-02-29 2013-02-28 Igg stimulated remyelination of peripheral nerves

Publications (1)

Publication Number Publication Date
DK2820042T3 true DK2820042T3 (da) 2019-10-28

Family

ID=47884569

Family Applications (2)

Application Number Title Priority Date Filing Date
DK13709675T DK2820042T3 (da) 2012-02-29 2013-02-28 Igg-stimuleret remyelinisering af perifere nerver
DK19180237.0T DK3590960T3 (da) 2012-02-29 2013-02-28 Igg-stimuleret remyelinisering af perifere nerver

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK19180237.0T DK3590960T3 (da) 2012-02-29 2013-02-28 Igg-stimuleret remyelinisering af perifere nerver

Country Status (21)

Country Link
US (5) US8986670B2 (da)
EP (2) EP3590960B1 (da)
JP (3) JP6335800B2 (da)
KR (3) KR102170615B1 (da)
CN (4) CN109966488A (da)
AR (2) AR090211A1 (da)
AU (3) AU2013203088B2 (da)
BR (1) BR112014021240A2 (da)
DK (2) DK2820042T3 (da)
EA (2) EA201892521A1 (da)
ES (2) ES2943585T3 (da)
FI (1) FI3590960T3 (da)
HK (2) HK1206035A1 (da)
IL (3) IL274512B1 (da)
MX (2) MX369444B (da)
NZ (1) NZ629867A (da)
PL (2) PL2820042T3 (da)
PT (2) PT2820042T (da)
SG (1) SG11201405302WA (da)
TW (3) TWI632158B (da)
WO (1) WO2013130826A2 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9690975B2 (en) * 2015-05-28 2017-06-27 Axogen Corporation Quantitative structural assay of a nerve graft
CN111655336A (zh) 2017-11-17 2020-09-11 纽约州立大学研究基金会 使用x射线微束辐射治疗受损周围神经的方法
WO2020146370A1 (en) * 2019-01-07 2020-07-16 Mallinckrodt Ard Ip Limited Methods of promoting remyelination

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE348942B (da) 1970-06-02 1972-09-18 Statens Bakteriologiska Labor
AT376367B (de) 1983-03-16 1984-11-12 Immuno Ag Verfahren zur herstellung von therapeutisch verabreichbaren, in endbehaeltern abgefuellten plasmaderivaten
DK166763C (da) 1983-03-16 1993-07-12 Immuno Ag Immunoglobulin-g-holdig fraktion
EP0124506B1 (de) 1983-05-02 1988-08-17 IMMUNO Aktiengesellschaft für chemisch-medizinische Produkte Verfahren zur Inaktivierung von vermehrungsfähigen Krankheitserregern
AT389815B (de) 1984-03-09 1990-02-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten
AT390560B (de) 1986-05-30 1990-05-25 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern
JP2871709B2 (ja) 1988-11-21 1999-03-17 住友製薬株式会社 免疫グロブリンg結合活性を有する新規な蛋白質プロテインh、該蛋白質をコードする遺伝子及び該蛋白質の製造法
US5177194A (en) 1990-02-01 1993-01-05 Baxter International, Inc. Process for purifying immune serum globulins
WO1992003536A1 (en) * 1990-08-15 1992-03-05 University Of Miami And Its School Of Medicine Autotransplantation of schwann cells to promote nervous system repair
AT402891B (de) 1991-06-20 1997-09-25 Immuno Ag Verfahren zur herstellung eines inaktivierten blutproduktes
WO1994013329A1 (de) 1992-12-16 1994-06-23 Immuno Aktiengesellschaft Verfahren zur herstellung eines virussicheren biologischen präparates
FR2706466B1 (fr) 1993-06-14 1995-08-25 Aetsrn Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré.
HRP940645A2 (en) 1993-10-06 1996-12-31 Immuno Ag Process for virus deactivation in the presence of polyalkylene glycol and the pharmaceutical preparation thus obtained
TW491855B (en) 1996-08-07 2002-06-21 Csl Ltd Purification of immunoglobulins
US5886154A (en) 1997-06-20 1999-03-23 Lebing; Wytold R. Chromatographic method for high yield purification and viral inactivation of antibodies
IL140155A (en) 1998-06-09 2005-12-18 Statens Seruminstitut Process for producing immunoglobulins for intravenous administration and other immunoglobulin products
SE0001128D0 (sv) 2000-03-30 2000-03-30 Amersham Pharm Biotech Ab A method of producing IgG
AU2000261978B2 (en) * 2000-05-10 2006-07-06 Mayo Foundation For Medical Education And Research Human igm antibodies with the capability of inducing remyelination, and diagnostic and therapeutic uses thereof particularly in the central nervous system
FR2824568B1 (fr) 2001-05-11 2004-04-09 Lab Francais Du Fractionnement Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique
JP2003070465A (ja) * 2001-08-31 2003-03-11 Keio Gijuku シュワン細胞の培養方法
CA2514117A1 (en) 2003-01-24 2004-08-12 Elan Pharmaceuticals, Inc. Composition for and treatment of demyelinating diseases and paralysis by administration of remyelinating agents
BRPI0507298A (pt) 2004-01-30 2007-07-03 Suomen Punainen Risti Veripalv processo para a produção de imunoglobulina segura a vìrus
CN1922207B (zh) 2004-02-27 2012-06-06 奥克特珐玛股份有限公司 提供纯化的、病毒安全的抗体制剂的方法
WO2008097503A2 (en) * 2007-02-02 2008-08-14 Biogen Idec Ma Inc. Use of semaphorin 6a for promoting myelination and oligodendrocyte differentiation
US7854703B2 (en) 2007-09-25 2010-12-21 Intel Corporation Peripheral neuropathy detection
CA2643496C (en) 2008-11-06 2015-02-03 Michael Fehlings The therapeutic use of igg as a neuroprotective agent
CN102021140B (zh) * 2009-09-18 2013-04-24 上海市第一人民医院 一种分离、纯化许旺细胞的方法

Also Published As

Publication number Publication date
EA201400966A1 (ru) 2014-12-30
FI3590960T3 (fi) 2023-04-25
TW201838654A (zh) 2018-11-01
CN107551269A (zh) 2018-01-09
IL234303B (en) 2020-09-30
TW201400502A (zh) 2014-01-01
CN109966488A (zh) 2019-07-05
US20210300997A1 (en) 2021-09-30
KR102170615B1 (ko) 2020-10-28
IL274512A (en) 2020-06-30
JP6335800B2 (ja) 2018-05-30
US9834593B2 (en) 2017-12-05
WO2013130826A2 (en) 2013-09-06
PT2820042T (pt) 2019-10-31
CN110343171A (zh) 2019-10-18
EA201892521A1 (ru) 2019-07-31
KR20140134690A (ko) 2014-11-24
IL277103A (en) 2020-10-29
AU2013203088A1 (en) 2013-09-19
ES2755056T3 (es) 2020-04-21
EP2820042A2 (en) 2015-01-07
SG11201405302WA (en) 2014-09-26
DK3590960T3 (da) 2023-04-24
JP2018030856A (ja) 2018-03-01
JP2020059705A (ja) 2020-04-16
PL2820042T3 (pl) 2020-03-31
BR112014021240A2 (pt) 2018-09-18
MX2019012496A (es) 2020-01-20
HK1206035A1 (en) 2015-12-31
IL274512B1 (en) 2024-03-01
MX369444B (es) 2019-11-08
MX2014010387A (es) 2015-09-25
AU2016201137A1 (en) 2016-03-10
WO2013130826A3 (en) 2013-12-05
AR090211A1 (es) 2014-10-29
TWI632158B (zh) 2018-08-11
JP2015508824A (ja) 2015-03-23
US20200216518A1 (en) 2020-07-09
US20130224150A1 (en) 2013-08-29
AU2016201137B2 (en) 2017-10-12
PT3590960T (pt) 2023-04-18
KR20220045087A (ko) 2022-04-12
NZ629867A (en) 2016-09-30
HK1248534A1 (zh) 2018-10-19
EP2820042B1 (en) 2019-07-24
JP6979990B2 (ja) 2021-12-15
US20180291087A1 (en) 2018-10-11
JP6637934B2 (ja) 2020-01-29
AU2018200026A1 (en) 2018-01-25
KR20200126005A (ko) 2020-11-05
PL3590960T3 (pl) 2023-07-17
ES2943585T3 (es) 2023-06-14
KR102673154B1 (ko) 2024-06-05
AU2013203088B2 (en) 2015-12-03
EP3590960A1 (en) 2020-01-08
AR117207A2 (es) 2021-07-21
AU2018200026B2 (en) 2019-12-05
US10494418B2 (en) 2019-12-03
TWI700297B (zh) 2020-08-01
EA032000B1 (ru) 2019-03-29
CN104302666A (zh) 2015-01-21
US20150232536A1 (en) 2015-08-20
TW201736398A (zh) 2017-10-16
EP3590960B1 (en) 2023-03-29
US8986670B2 (en) 2015-03-24

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