IL136738A0 - Inhibition of p38 kinase activity using substituted heterocyclic ureas - Google Patents
Inhibition of p38 kinase activity using substituted heterocyclic ureasInfo
- Publication number
- IL136738A0 IL136738A0 IL13673898A IL13673898A IL136738A0 IL 136738 A0 IL136738 A0 IL 136738A0 IL 13673898 A IL13673898 A IL 13673898A IL 13673898 A IL13673898 A IL 13673898A IL 136738 A0 IL136738 A0 IL 136738A0
- Authority
- IL
- Israel
- Prior art keywords
- inhibition
- kinase activity
- substituted heterocyclic
- heterocyclic ureas
- ureas
- Prior art date
Links
Classifications
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99575097A | 1997-12-22 | 1997-12-22 | |
PCT/US1998/026080 WO1999032111A1 (fr) | 1997-12-22 | 1998-12-22 | Inhibition de l'activite de p38 kinase au moyen d'urees heterocycliques substituees |
Publications (1)
Publication Number | Publication Date |
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IL136738A0 true IL136738A0 (en) | 2001-06-14 |
Family
ID=25542167
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13673898A IL136738A0 (en) | 1997-12-22 | 1998-12-22 | Inhibition of p38 kinase activity using substituted heterocyclic ureas |
IL136738A IL136738A (en) | 1997-12-22 | 2000-06-12 | USE OF SUBSTITUTED HETEROCYCLIC UREAS FOR THE PREPARATION OF MEDICAMENTS FOR TREATING A DISEASE MEDIATED BY p38 OTHER THAN CANCER |
IL170201A IL170201A (en) | 1997-12-22 | 2005-08-10 | Sustituted heterocyclic ureas and pharmaceutical compositions comprising them |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL136738A IL136738A (en) | 1997-12-22 | 2000-06-12 | USE OF SUBSTITUTED HETEROCYCLIC UREAS FOR THE PREPARATION OF MEDICAMENTS FOR TREATING A DISEASE MEDIATED BY p38 OTHER THAN CANCER |
IL170201A IL170201A (en) | 1997-12-22 | 2005-08-10 | Sustituted heterocyclic ureas and pharmaceutical compositions comprising them |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1041982B1 (fr) |
JP (1) | JP4403482B2 (fr) |
AT (1) | ATE529109T1 (fr) |
AU (1) | AU739642B2 (fr) |
CA (1) | CA2315720A1 (fr) |
DE (1) | DE1041982T1 (fr) |
ES (1) | ES2154253T3 (fr) |
IL (3) | IL136738A0 (fr) |
MX (1) | MXPA00006233A (fr) |
WO (1) | WO1999032111A1 (fr) |
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CA3089566A1 (fr) | 2018-01-31 | 2019-08-08 | Deciphera Pharmaceuticals, Llc | Polytherapie pour le traitement de tumeurs stromales gastro-intestinales |
CA3093025A1 (fr) | 2018-06-12 | 2019-12-19 | Vtv Therapeutics Llc | Utilisations therapeutiques d'activateurs de glucokinase en combinaison avec de l'insuline ou des analogues d'insuline |
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WO2021030405A1 (fr) | 2019-08-12 | 2021-02-18 | Deciphera Pharmaceuticals, Llc | Ripretinib pour le traitement de tumeurs stromales gastro-intestinales |
LT4084778T (lt) | 2019-12-30 | 2024-01-25 | Deciphera Pharmaceuticals, Llc | Amorfinės kinazės inhibitoriaus vaistinės formos ir jų panaudojimo būdai |
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US3646059A (en) * | 1969-05-05 | 1972-02-29 | Du Pont | Plant growth regulatory ureidopyrazoles |
KR0133550B1 (ko) * | 1991-01-21 | 1998-04-23 | 요시또시 가즈오 | 3-벤질리덴-1-카르바모일-2-피롤리돈 유사체 |
US5162360A (en) * | 1991-06-24 | 1992-11-10 | Warner-Lambert Company | 2-heteroatom containing urea and thiourea ACAT inhibitors |
DE4227989A1 (de) | 1992-08-21 | 1994-06-09 | Schering Ag | Mittel zur transdermalen Applikation enthaltend 3-Keto-desogestrel |
JP3377529B2 (ja) | 1993-09-17 | 2003-02-17 | スミスクライン・ビーチャム・コーポレイション | 薬物結合タンパク質 |
US5559137A (en) * | 1994-05-16 | 1996-09-24 | Smithkline Beecham Corp. | Compounds |
AU7726898A (en) * | 1997-05-22 | 1998-12-11 | G.D. Searle & Co. | Pyrazole derivatives as p38 kinase inhibitors |
EP0983260A2 (fr) * | 1997-05-22 | 2000-03-08 | G.D. Searle & Co. | PYRAZOLES 3(5)-HETEROARYL SUBSTITUEES UTILISEES COMME INHIBITEURS DE KINASE p38 |
PT1019040E (pt) * | 1997-05-23 | 2005-01-31 | Bayer Pharmaceuticals Corp | Inibicao da actividade de p38-quinase por meio de arilureias |
AU7966198A (en) * | 1997-06-13 | 1998-12-30 | Smithkline Beecham Corporation | Novel pyrazole and pyrazoline substituted compounds |
JP2001521934A (ja) * | 1997-11-03 | 2001-11-13 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | 抗炎症薬としての芳香族ヘテロ環式化合物 |
KR100571588B1 (ko) * | 1997-12-22 | 2006-04-17 | 바이엘 코포레이션 | 치환 헤테로시클릭 우레아를 이용한 raf 키나제의 억제 |
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ATE346600T1 (de) * | 1997-12-22 | 2006-12-15 | Bayer Pharmaceuticals Corp | Inhibierung der p38 kinase-aktivität durch die verwendung von aryl- und heteroarylsubstituierten harnstoffen |
-
1998
- 1998-12-22 CA CA002315720A patent/CA2315720A1/fr not_active Abandoned
- 1998-12-22 JP JP2000525102A patent/JP4403482B2/ja not_active Expired - Fee Related
- 1998-12-22 ES ES98964709T patent/ES2154253T3/es not_active Expired - Lifetime
- 1998-12-22 AT AT98964709T patent/ATE529109T1/de not_active IP Right Cessation
- 1998-12-22 EP EP98964709A patent/EP1041982B1/fr not_active Expired - Lifetime
- 1998-12-22 IL IL13673898A patent/IL136738A0/xx active IP Right Grant
- 1998-12-22 MX MXPA00006233A patent/MXPA00006233A/es not_active Application Discontinuation
- 1998-12-22 DE DE1041982T patent/DE1041982T1/de active Pending
- 1998-12-22 AU AU19971/99A patent/AU739642B2/en not_active Ceased
- 1998-12-22 WO PCT/US1998/026080 patent/WO1999032111A1/fr active Application Filing
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2000
- 2000-06-12 IL IL136738A patent/IL136738A/en not_active IP Right Cessation
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- 2005-08-10 IL IL170201A patent/IL170201A/en not_active IP Right Cessation
Also Published As
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AU739642B2 (en) | 2001-10-18 |
ES2154253T1 (es) | 2001-04-01 |
CA2315720A1 (fr) | 1999-07-01 |
WO1999032111A1 (fr) | 1999-07-01 |
EP1041982A4 (fr) | 2006-06-14 |
EP1041982B1 (fr) | 2011-10-19 |
ES2154253T3 (es) | 2012-01-27 |
DE1041982T1 (de) | 2001-06-07 |
JP4403482B2 (ja) | 2010-01-27 |
JP2001526223A (ja) | 2001-12-18 |
IL170201A (en) | 2006-12-31 |
ATE529109T1 (de) | 2011-11-15 |
MXPA00006233A (es) | 2002-09-18 |
EP1041982A1 (fr) | 2000-10-11 |
IL136738A (en) | 2007-06-17 |
AU1997199A (en) | 1999-07-12 |
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