IL128323A - Kinase 2 purine inhibitors depend on cyclin - Google Patents

Kinase 2 purine inhibitors depend on cyclin

Info

Publication number
IL128323A
IL128323A IL12832397A IL12832397A IL128323A IL 128323 A IL128323 A IL 128323A IL 12832397 A IL12832397 A IL 12832397A IL 12832397 A IL12832397 A IL 12832397A IL 128323 A IL128323 A IL 128323A
Authority
IL
Israel
Prior art keywords
isopropyl
substituted
alkyl
diethanolamine
methoxybenzylamino
Prior art date
Application number
IL12832397A
Other languages
English (en)
Hebrew (he)
Other versions
IL128323A0 (en
Original Assignee
Cv Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cv Therapeutics Inc filed Critical Cv Therapeutics Inc
Priority to IL14500097A priority Critical patent/IL145000A0/xx
Publication of IL128323A0 publication Critical patent/IL128323A0/xx
Publication of IL128323A publication Critical patent/IL128323A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL12832397A 1996-08-02 1997-08-01 Kinase 2 purine inhibitors depend on cyclin IL128323A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL14500097A IL145000A0 (en) 1996-08-02 1997-08-01 Purine inhibitors of cyclin dependent kinase 2

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/692,012 US5866702A (en) 1996-08-02 1996-08-02 Purine inhibitors of cyclin dependent kinase 2
PCT/US1997/013386 WO1998005335A1 (en) 1996-08-02 1997-08-01 PURINE INHIBITORS OF CYCLIN DEPENDENT KINASE 2 AND IλB-$g(a)

Publications (2)

Publication Number Publication Date
IL128323A0 IL128323A0 (en) 2000-01-31
IL128323A true IL128323A (en) 2001-11-25

Family

ID=24778922

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12832397A IL128323A (en) 1996-08-02 1997-08-01 Kinase 2 purine inhibitors depend on cyclin

Country Status (25)

Country Link
US (1) US5866702A (cg-RX-API-DMAC7.html)
EP (1) EP1021186B1 (cg-RX-API-DMAC7.html)
JP (1) JP2000515550A (cg-RX-API-DMAC7.html)
KR (1) KR100403336B1 (cg-RX-API-DMAC7.html)
CN (1) CN1161356C (cg-RX-API-DMAC7.html)
AT (1) ATE298572T1 (cg-RX-API-DMAC7.html)
AU (1) AU731778B2 (cg-RX-API-DMAC7.html)
BR (1) BR9710801A (cg-RX-API-DMAC7.html)
CA (1) CA2262454C (cg-RX-API-DMAC7.html)
CZ (1) CZ299381B6 (cg-RX-API-DMAC7.html)
DE (1) DE69733674T2 (cg-RX-API-DMAC7.html)
DK (1) DK1021186T3 (cg-RX-API-DMAC7.html)
ES (1) ES2242981T3 (cg-RX-API-DMAC7.html)
GE (1) GEP20022786B (cg-RX-API-DMAC7.html)
HU (1) HUP9902414A3 (cg-RX-API-DMAC7.html)
IL (1) IL128323A (cg-RX-API-DMAC7.html)
NO (1) NO323775B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ334061A (cg-RX-API-DMAC7.html)
PL (1) PL189775B1 (cg-RX-API-DMAC7.html)
PT (1) PT1021186E (cg-RX-API-DMAC7.html)
RU (1) RU2220968C2 (cg-RX-API-DMAC7.html)
SI (1) SI1021186T1 (cg-RX-API-DMAC7.html)
TR (1) TR199900683T2 (cg-RX-API-DMAC7.html)
UA (1) UA71890C2 (cg-RX-API-DMAC7.html)
WO (1) WO1998005335A1 (cg-RX-API-DMAC7.html)

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