IL117252A - Cyclic derivatives of the vasoactive intestinal peptide their preparation and pharmaceutical compositions containing them - Google Patents

Cyclic derivatives of the vasoactive intestinal peptide their preparation and pharmaceutical compositions containing them

Info

Publication number
IL117252A
IL117252A IL11725292A IL11725292A IL117252A IL 117252 A IL117252 A IL 117252A IL 11725292 A IL11725292 A IL 11725292A IL 11725292 A IL11725292 A IL 11725292A IL 117252 A IL117252 A IL 117252A
Authority
IL
Israel
Prior art keywords
peptide
pharmaceutical compositions
preparation
amino acid
compositions containing
Prior art date
Application number
IL11725292A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL117252A publication Critical patent/IL117252A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57563Vasoactive intestinal peptide [VIP]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/17Vasoactive intestinal peptides; related peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/27Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL11725292A 1991-10-11 1992-10-09 Cyclic derivatives of the vasoactive intestinal peptide their preparation and pharmaceutical compositions containing them IL117252A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77374791A 1991-10-11 1991-10-11
IL103396A IL103396A (en) 1991-10-11 1992-10-09 Cyclic derivatives of the vasoactive intestinal peptide, their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
IL117252A true IL117252A (en) 1999-11-30

Family

ID=25099195

Family Applications (3)

Application Number Title Priority Date Filing Date
IL11725292A IL117252A (en) 1991-10-11 1992-10-09 Cyclic derivatives of the vasoactive intestinal peptide their preparation and pharmaceutical compositions containing them
IL103396A IL103396A (en) 1991-10-11 1992-10-09 Cyclic derivatives of the vasoactive intestinal peptide, their preparation and pharmaceutical compositions containing them
IL11725296A IL117252A0 (en) 1991-10-11 1996-02-23 Cyclic derivatives of the vasoactive intestinal peptide their preparation and pharmaceutical compositions containing them

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL103396A IL103396A (en) 1991-10-11 1992-10-09 Cyclic derivatives of the vasoactive intestinal peptide, their preparation and pharmaceutical compositions containing them
IL11725296A IL117252A0 (en) 1991-10-11 1996-02-23 Cyclic derivatives of the vasoactive intestinal peptide their preparation and pharmaceutical compositions containing them

Country Status (26)

Country Link
US (1) US5677419A (cs)
EP (1) EP0536741B1 (cs)
JP (1) JP2515473B2 (cs)
KR (1) KR970001580B1 (cs)
CN (3) CN1034943C (cs)
AT (1) ATE132165T1 (cs)
AU (1) AU656230B2 (cs)
BG (1) BG61125B2 (cs)
BR (1) BR9203959A (cs)
CA (1) CA2080272C (cs)
CZ (1) CZ281818B6 (cs)
DE (1) DE69207138T2 (cs)
DK (1) DK0536741T3 (cs)
ES (1) ES2082317T3 (cs)
FI (2) FI111646B (cs)
GR (1) GR3019326T3 (cs)
HU (2) HUT62606A (cs)
IL (3) IL117252A (cs)
MX (1) MX9205822A (cs)
NO (3) NO304523B1 (cs)
NZ (1) NZ244644A (cs)
RU (1) RU2095368C1 (cs)
SK (1) SK279399B6 (cs)
TW (1) TW305846B (cs)
UY (2) UY23488A1 (cs)
ZA (1) ZA927724B (cs)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872803B1 (en) 1993-09-21 2005-03-29 Kyowa Hakko Kogyo Co., Ltd. Peptides
CN1186355C (zh) * 1996-02-09 2005-01-26 霍夫曼-拉罗奇有限公司 血管活性肠肽类似物的合成
ATE380038T1 (de) 1996-07-12 2007-12-15 Immunomedics Inc Radiometall-bindende peptide analoge
WO1998002453A2 (en) * 1996-07-15 1998-01-22 Universite Libre De Bruxelles Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor
US6972319B1 (en) 1999-09-28 2005-12-06 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use
CA2379604A1 (en) * 1999-09-28 2001-04-05 Bayer Corporation Pituitary adenylate cyclase activating peptide (pacap) receptor 3 (r3) agonists and their pharmacological methods of use
EP1257576B1 (en) 2000-02-18 2004-09-15 Dabur Research Foundation Vasoactive intestinal peptide analogs
WO2001060863A1 (en) 2000-02-18 2001-08-23 Dabur Research Foundation Radiolabeled vasoactive intestinal peptide analogs for diagnosis and radiotherapy
US6828304B1 (en) 2000-07-31 2004-12-07 Dabur Research Foundation Peptides for treatment of cancer
US7507714B2 (en) * 2000-09-27 2009-03-24 Bayer Corporation Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
US20040063631A1 (en) 2000-11-28 2004-04-01 Lutz-Henning Block Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension
EP1515745B1 (en) 2002-06-10 2009-03-18 MondoBIOTECH Licensing Out AG Use of compounds having the biological activity of vasoactive intestinal peptide for the treatment of sarcoidosis
WO2005072385A2 (en) * 2004-01-27 2005-08-11 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use
US20080085860A1 (en) * 2004-08-18 2008-04-10 Eli Lilly And Company Selective Vpac2 Receptor Peptide Agonists
EP1781694A1 (en) * 2004-08-18 2007-05-09 Eli Lilly And Company Selective vpac2 receptor peptide agonists
RU2304146C2 (ru) * 2005-10-17 2007-08-10 Закрытое акционерное общество "Эпитек" Способ стабилизации петлеобразной структуры синтетических пептидов с помощью n- и c-концевых модификаций
JP2009528376A (ja) * 2006-02-28 2009-08-06 イーライ リリー アンド カンパニー 選択的vpac2受容体ペプチドアゴニスト
MX2009000013A (es) * 2006-07-06 2009-01-23 Hoffmann La Roche Nuevos analogos del peptido intestinal vasoactivo.
CN101906144B (zh) * 2009-06-03 2013-06-19 首都医科大学 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
US9029505B2 (en) 2009-08-14 2015-05-12 Phasebio Pharmaceuticals, Inc. Modified vasoactive intestinal peptides
US9782454B2 (en) * 2010-04-22 2017-10-10 Longevity Biotech, Inc. Highly active polypeptides and methods of making and using the same
WO2012170524A1 (en) 2011-06-06 2012-12-13 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
EP2968469A4 (en) 2013-03-15 2016-08-31 Longevity Biotech Inc PEPTIDES COMPRISING NON-ENDOGENIC AMINO ACIDS AND METHODS OF MAKING AND USING SAME
GB201421647D0 (en) * 2014-12-05 2015-01-21 Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
CN107427556B (zh) 2015-02-09 2022-02-25 费斯生物制药公司 用于治疗肌肉疾病和病症的方法和组合物
CN109790202B (zh) 2016-09-30 2022-09-13 富士胶片株式会社 环肽、亲和层析载体、标记抗体、抗体药物复合体及药物制剂
CA3171988A1 (en) * 2020-02-22 2021-08-26 Jcr Pharmaceuticals Co., Ltd. Human transferrin receptor binding peptide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
US4835252A (en) * 1987-02-26 1989-05-30 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
GB8729802D0 (en) * 1987-12-22 1988-02-03 Beecham Group Plc Novel compounds
US5084442A (en) * 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5141924A (en) * 1989-06-30 1992-08-25 Hoffmann-La Roche, Inc. Synthetic vasoactive intestinal peptide analogs

Also Published As

Publication number Publication date
CN1034943C (zh) 1997-05-21
DE69207138T2 (de) 1996-06-13
NZ244644A (en) 1995-04-27
CA2080272C (en) 2002-09-17
AU2622892A (en) 1993-04-22
IL103396A (en) 1997-11-20
GR3019326T3 (en) 1996-06-30
NO975023L (no) 1993-04-13
NO975023D0 (no) 1997-10-31
FI924580L (fi) 1993-04-12
ES2082317T3 (es) 1996-03-16
FI20002041A7 (fi) 2000-09-15
HU9203194D0 (en) 1992-12-28
ATE132165T1 (de) 1996-01-15
EP0536741B1 (en) 1995-12-27
KR970001580B1 (ko) 1997-02-11
DK0536741T3 (da) 1996-04-22
NO980377L (no) 1993-04-13
FI20002041L (fi) 2000-09-15
JPH05213996A (ja) 1993-08-24
FI924580A0 (fi) 1992-10-09
NO923929D0 (no) 1992-10-09
BR9203959A (pt) 1993-04-27
SK308692A3 (en) 1995-03-08
HUT62606A (en) 1993-05-28
CZ281818B6 (cs) 1997-02-12
US5677419A (en) 1997-10-14
CN1152579A (zh) 1997-06-25
NO980377D0 (no) 1998-01-28
TW305846B (cs) 1997-05-21
UY25084A1 (es) 1998-12-21
SK279399B6 (sk) 1998-11-04
FI111646B (fi) 2003-08-29
JP2515473B2 (ja) 1996-07-10
CA2080272A1 (en) 1993-04-12
NO923929L (no) 1993-04-13
BG61125B2 (bg) 1996-11-29
CN1153785A (zh) 1997-07-09
ZA927724B (en) 1994-04-07
AU656230B2 (en) 1995-01-27
CN1072415A (zh) 1993-05-26
RU2095368C1 (ru) 1997-11-10
CZ308692A3 (en) 1993-08-11
DE69207138D1 (de) 1996-02-08
IL103396A0 (en) 1993-03-15
UY23488A1 (es) 1993-04-20
HU211534A9 (en) 1995-12-28
KR930007972A (ko) 1993-05-20
EP0536741A3 (cs) 1994-04-06
CN1198841C (zh) 2005-04-27
MX9205822A (es) 1993-06-01
NO304523B1 (no) 1999-01-04
EP0536741A2 (en) 1993-04-14
CN1225473C (zh) 2005-11-02
IL117252A0 (en) 1996-06-18

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH1 Patent not in force