DK0536741T3 - Cykliske VIP-analoger - Google Patents
Cykliske VIP-analogerInfo
- Publication number
- DK0536741T3 DK0536741T3 DK92117185.6T DK92117185T DK0536741T3 DK 0536741 T3 DK0536741 T3 DK 0536741T3 DK 92117185 T DK92117185 T DK 92117185T DK 0536741 T3 DK0536741 T3 DK 0536741T3
- Authority
- DK
- Denmark
- Prior art keywords
- peptide
- amino acid
- vasoactive
- chain
- cyclic
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 6
- 230000002227 vasoactive effect Effects 0.000 abstract 3
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 125000004122 cyclic group Chemical group 0.000 abstract 2
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/17—Vasoactive intestinal peptides; related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77374791A | 1991-10-11 | 1991-10-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0536741T3 true DK0536741T3 (da) | 1996-04-22 |
Family
ID=25099195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92117185.6T DK0536741T3 (da) | 1991-10-11 | 1992-10-08 | Cykliske VIP-analoger |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US5677419A (cs) |
| EP (1) | EP0536741B1 (cs) |
| JP (1) | JP2515473B2 (cs) |
| KR (1) | KR970001580B1 (cs) |
| CN (3) | CN1034943C (cs) |
| AT (1) | ATE132165T1 (cs) |
| AU (1) | AU656230B2 (cs) |
| BG (1) | BG61125B2 (cs) |
| BR (1) | BR9203959A (cs) |
| CA (1) | CA2080272C (cs) |
| CZ (1) | CZ281818B6 (cs) |
| DE (1) | DE69207138T2 (cs) |
| DK (1) | DK0536741T3 (cs) |
| ES (1) | ES2082317T3 (cs) |
| FI (2) | FI111646B (cs) |
| GR (1) | GR3019326T3 (cs) |
| HU (2) | HUT62606A (cs) |
| IL (3) | IL103396A (cs) |
| MX (1) | MX9205822A (cs) |
| NO (3) | NO304523B1 (cs) |
| NZ (1) | NZ244644A (cs) |
| RU (1) | RU2095368C1 (cs) |
| SK (1) | SK279399B6 (cs) |
| TW (1) | TW305846B (cs) |
| UY (2) | UY23488A1 (cs) |
| ZA (1) | ZA927724B (cs) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6872803B1 (en) | 1993-09-21 | 2005-03-29 | Kyowa Hakko Kogyo Co., Ltd. | Peptides |
| HUP9900961A3 (en) * | 1996-02-09 | 2001-06-28 | Hoffmann La Roche | Synthesis of vip analog |
| ATE380038T1 (de) | 1996-07-12 | 2007-12-15 | Immunomedics Inc | Radiometall-bindende peptide analoge |
| WO1998002453A2 (en) * | 1996-07-15 | 1998-01-22 | Universite Libre De Bruxelles | Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor |
| US6972319B1 (en) | 1999-09-28 | 2005-12-06 | Bayer Pharmaceuticals Corporation | Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use |
| DE60039111D1 (de) * | 1999-09-28 | 2008-07-17 | Bayer Corp | Agonisten des rezeptors 3 (r3) von pituitary adenylate cyclase aktivierendem peptid (pacap) und ihre pharmakologische verwendung |
| WO2001060862A1 (en) | 2000-02-18 | 2001-08-23 | Dabur Research Foundation | Vasoactive intestinal peptide analogs |
| DE60033697D1 (de) | 2000-02-18 | 2007-04-12 | Dabur Res Foundation Sahibabad | Radiomarkierte vip-analoge zur diagnose und therapie |
| US6828304B1 (en) | 2000-07-31 | 2004-12-07 | Dabur Research Foundation | Peptides for treatment of cancer |
| US7507714B2 (en) * | 2000-09-27 | 2009-03-24 | Bayer Corporation | Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use |
| AU2002220720B2 (en) | 2000-11-28 | 2006-09-14 | Mondobiotech Ag | Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension |
| CA2488358A1 (en) | 2002-06-10 | 2003-12-18 | Mondobiotech Laboratories Anstalt | Use of compounds having the biological activity of vasoactive intestinal peptide for the treatment of sarcoidosis |
| BRPI0507177A (pt) * | 2004-01-27 | 2007-06-26 | Bayer Pharmaceuticals Corp | agonistas (vpac2) do receptor peptìdico de ativação de adenilato ciclase pituitários (pacap) e seus métodos farmacológicos de uso |
| US20080085860A1 (en) * | 2004-08-18 | 2008-04-10 | Eli Lilly And Company | Selective Vpac2 Receptor Peptide Agonists |
| EP1781692A2 (en) * | 2004-08-18 | 2007-05-09 | Eli Lilly And Company | Selective vpac2 receptor peptide agonists |
| RU2304146C2 (ru) * | 2005-10-17 | 2007-08-10 | Закрытое акционерное общество "Эпитек" | Способ стабилизации петлеобразной структуры синтетических пептидов с помощью n- и c-концевых модификаций |
| US20100048460A1 (en) * | 2006-02-28 | 2010-02-25 | Lianshan Zhang | Selective vpac2 receptor peptide agonists |
| AU2007271274A1 (en) * | 2006-07-06 | 2008-01-10 | F. Hoffmann-La Roche Ag | Analogs of vasoactive intestinal peptide |
| CN101906144B (zh) * | 2009-06-03 | 2013-06-19 | 首都医科大学 | 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用 |
| PT2464370T (pt) | 2009-08-14 | 2017-05-17 | Phasebio Pharmaceuticals Inc | Péptidos vasoativos intestinais modificados |
| US9782454B2 (en) * | 2010-04-22 | 2017-10-10 | Longevity Biotech, Inc. | Highly active polypeptides and methods of making and using the same |
| US9561262B2 (en) | 2011-06-06 | 2017-02-07 | Phasebio Pharmaceuticals, Inc. | Use of modified vasoactive intestinal peptides in the treatment of hypertension |
| US9789164B2 (en) | 2013-03-15 | 2017-10-17 | Longevity Biotech, Inc. | Peptides comprising non-natural amino acids and methods of making and using the same |
| GB201421647D0 (en) * | 2014-12-05 | 2015-01-21 | Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie | CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases |
| ES2822598T3 (es) | 2015-02-09 | 2021-05-04 | Phasebio Pharmaceuticals Inc | Métodos y composiciones para tratar enfermedades y trastornos musculares |
| EP4043479A1 (en) | 2016-09-30 | 2022-08-17 | FUJIFILM Corporation | Cyclic peptide, affinity chromatography support, labeled antibody, antibody-drug conjugate, and pharmaceutical preparation |
| TW202140513A (zh) * | 2020-02-22 | 2021-11-01 | 日商Ｊｃｒ製藥股份有限公司 | 人類運鐵蛋白受體結合肽 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8427651D0 (en) * | 1984-11-01 | 1984-12-05 | Beecham Group Plc | Compounds |
| US4835252A (en) * | 1987-02-26 | 1989-05-30 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Vasoactive intestinal peptide analogs |
| GB8729802D0 (en) * | 1987-12-22 | 1988-02-03 | Beecham Group Plc | Novel compounds |
| US5084442A (en) * | 1988-09-06 | 1992-01-28 | Hoffmann-La Roche Inc. | Cyclic growth hormone releasing factor analogs and method for the manufacture thereof |
| US5141924A (en) * | 1989-06-30 | 1992-08-25 | Hoffmann-La Roche, Inc. | Synthetic vasoactive intestinal peptide analogs |
-
1992
- 1992-10-06 AU AU26228/92A patent/AU656230B2/en not_active Ceased
- 1992-10-07 ZA ZA927724A patent/ZA927724B/xx unknown
- 1992-10-07 NZ NZ244644A patent/NZ244644A/en unknown
- 1992-10-08 ES ES92117185T patent/ES2082317T3/es not_active Expired - Lifetime
- 1992-10-08 TW TW081107995A patent/TW305846B/zh active
- 1992-10-08 DK DK92117185.6T patent/DK0536741T3/da active
- 1992-10-08 EP EP92117185A patent/EP0536741B1/en not_active Expired - Lifetime
- 1992-10-08 RU SU925053217A patent/RU2095368C1/ru active
- 1992-10-08 AT AT92117185T patent/ATE132165T1/de not_active IP Right Cessation
- 1992-10-08 DE DE69207138T patent/DE69207138T2/de not_active Expired - Lifetime
- 1992-10-09 CA CA002080272A patent/CA2080272C/en not_active Expired - Fee Related
- 1992-10-09 IL IL103396A patent/IL103396A/xx not_active IP Right Cessation
- 1992-10-09 SK SK3086-92A patent/SK279399B6/sk unknown
- 1992-10-09 HU HU9203194A patent/HUT62606A/hu unknown
- 1992-10-09 UY UY23488A patent/UY23488A1/es not_active IP Right Cessation
- 1992-10-09 NO NO923929A patent/NO304523B1/no not_active IP Right Cessation
- 1992-10-09 MX MX9205822A patent/MX9205822A/es not_active IP Right Cessation
- 1992-10-09 IL IL11725292A patent/IL117252A/xx not_active IP Right Cessation
- 1992-10-09 FI FI924580A patent/FI111646B/fi active
- 1992-10-09 CZ CS923086A patent/CZ281818B6/cs not_active IP Right Cessation
- 1992-10-09 JP JP4297835A patent/JP2515473B2/ja not_active Expired - Fee Related
- 1992-10-10 KR KR1019920018660A patent/KR970001580B1/ko not_active Expired - Fee Related
- 1992-10-10 CN CN92113069A patent/CN1034943C/zh not_active Expired - Fee Related
- 1992-10-13 BR BR929203959A patent/BR9203959A/pt not_active Application Discontinuation
-
1994
- 1994-02-28 BG BG098608A patent/BG61125B2/bg unknown
- 1994-09-19 US US08/308,729 patent/US5677419A/en not_active Expired - Lifetime
-
1995
- 1995-06-21 HU HU95P/P00297P patent/HU211534A9/hu unknown
-
1996
- 1996-02-23 IL IL11725296A patent/IL117252A0/xx unknown
- 1996-03-15 GR GR960400712T patent/GR3019326T3/el unknown
- 1996-08-15 CN CNB961118075A patent/CN1225473C/zh not_active Expired - Fee Related
- 1996-08-15 CN CNB961115238A patent/CN1198841C/zh not_active Expired - Fee Related
-
1997
- 1997-10-31 NO NO975023A patent/NO975023D0/no not_active Application Discontinuation
-
1998
- 1998-01-28 NO NO980377A patent/NO980377D0/no unknown
- 1998-07-06 UY UY25084A patent/UY25084A1/es unknown
-
2000
- 2000-09-15 FI FI20002041A patent/FI20002041A7/fi unknown
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