IL108851A - Polypeptide bombesin antagonists, their preparation and pharmaceutical preparations containing them - Google Patents

Polypeptide bombesin antagonists, their preparation and pharmaceutical preparations containing them

Info

Publication number
IL108851A
IL108851A IL10885194A IL10885194A IL108851A IL 108851 A IL108851 A IL 108851A IL 10885194 A IL10885194 A IL 10885194A IL 10885194 A IL10885194 A IL 10885194A IL 108851 A IL108851 A IL 108851A
Authority
IL
Israel
Prior art keywords
phenyl
alkyl
hydrogen
moiety
10alkyl
Prior art date
Application number
IL10885194A
Other languages
English (en)
Other versions
IL108851A0 (en
Original Assignee
Univ Tulane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tulane filed Critical Univ Tulane
Publication of IL108851A0 publication Critical patent/IL108851A0/xx
Priority to IL15499503A priority Critical patent/IL154995A0/xx
Publication of IL108851A publication Critical patent/IL108851A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086—Bombesin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL10885194A 1993-03-15 1994-03-03 Polypeptide bombesin antagonists, their preparation and pharmaceutical preparations containing them IL108851A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL15499503A IL154995A0 (en) 1993-03-15 2003-03-19 Polypeptide bombesin antagonists, their preparation and pharmaceutical preparations containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/031,325 US5369094A (en) 1990-11-29 1993-03-15 Polypeptide bombesin antagonists

Publications (2)

Publication Number Publication Date
IL108851A0 IL108851A0 (en) 1994-06-24
IL108851A true IL108851A (en) 2003-05-29

Family

ID=21858823

Family Applications (2)

Application Number Title Priority Date Filing Date
IL10885194A IL108851A (en) 1993-03-15 1994-03-03 Polypeptide bombesin antagonists, their preparation and pharmaceutical preparations containing them
IL15499503A IL154995A0 (en) 1993-03-15 2003-03-19 Polypeptide bombesin antagonists, their preparation and pharmaceutical preparations containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL15499503A IL154995A0 (en) 1993-03-15 2003-03-19 Polypeptide bombesin antagonists, their preparation and pharmaceutical preparations containing them

Country Status (27)

Country Link
US (1) US5369094A (de)
EP (1) EP0646127B1 (de)
JP (1) JP3838656B2 (de)
KR (1) KR100306506B1 (de)
AT (1) ATE167874T1 (de)
AU (1) AU666270B2 (de)
BR (1) BR9404341A (de)
CA (1) CA2135787C (de)
CZ (1) CZ286750B6 (de)
DE (1) DE69411342T2 (de)
DK (1) DK0646127T3 (de)
EE (1) EE03180B1 (de)
ES (1) ES2120615T3 (de)
FI (1) FI945378A (de)
HR (1) HRP940164B1 (de)
HU (1) HU218288B (de)
IL (2) IL108851A (de)
NO (1) NO313418B1 (de)
NZ (2) NZ299913A (de)
PL (1) PL180372B1 (de)
RU (1) RU2114118C1 (de)
SI (1) SI9420001B (de)
SK (1) SK282267B6 (de)
TW (1) TW325478B (de)
UA (1) UA34456C2 (de)
WO (1) WO1994021674A1 (de)
ZA (1) ZA941767B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877277A (en) 1987-09-24 1999-03-02 Biomeasure, Inc. Octapeptide bombesin analogs
US5723578A (en) * 1987-09-24 1998-03-03 The Administrators Of Tulane Educational Fund Peptide analogs of bombesin
US5650395A (en) * 1995-03-13 1997-07-22 Hurel; Steven Treatment of pulmonary hypertension
US6989371B1 (en) 1996-08-16 2006-01-24 Dabur Research Foundation Bombesin analogs for treatment of cancer
DE69840647D1 (de) 1997-04-22 2009-04-23 Curator Of The University Of M Konjugate aus peptiden, die liganden von gastrinrezeptoren sind
KR20040062416A (ko) * 2000-11-17 2004-07-07 워너-램버트 캄파니 엘엘씨 봄베신 길항제를 이용한 성기능 장애의 치료
ATE435035T1 (de) * 2003-01-13 2009-07-15 Bracco Imaging Spa Verbesserte linker für radiopharmazeutische verbindungen
US7922998B2 (en) * 2003-01-13 2011-04-12 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7850947B2 (en) * 2003-01-13 2010-12-14 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US20060239923A1 (en) * 2003-01-13 2006-10-26 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7611692B2 (en) 2003-01-13 2009-11-03 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7226577B2 (en) * 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
US8420050B2 (en) * 2003-01-13 2013-04-16 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US8709998B2 (en) 2003-04-22 2014-04-29 Ipsen Pharma S.A.S. Peptide vectors
US7795385B2 (en) * 2004-12-17 2010-09-14 Bexar Global, Inc. Use of bombesin/gastrin-releasing peptide antagonists for the treatment of inflammatory conditions, acute lung injury and bipolar disorder
FR2918566B1 (fr) * 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
EP2100900A1 (de) * 2008-03-07 2009-09-16 Universitätsspital Basel Bombesin-analoge Peptid-antagonistische Konjugate
EP2198878A1 (de) * 2008-12-18 2010-06-23 University Of Miami Polypeptide Bombesinantagonisten
JP2013507364A (ja) 2009-10-07 2013-03-04 メルク・シャープ・エンド・ドーム・コーポレイション 新規なｔｒｐａ１アンタゴニスト

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5084555A (en) * 1989-08-21 1992-01-28 The Administrators Of The Tulane Educational Fund An octapeptide bombesin analog
JP2795449B2 (ja) * 1987-09-24 1998-09-10 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 治療用ペプチド
US5162497A (en) * 1987-09-24 1992-11-10 The Administrators Of The Tulane Educational Fund Bradykinin analogs with non-peptide bond
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
GB8813356D0 (en) * 1988-06-06 1988-07-13 Ici Plc Polypeptide compounds
GR1000608B (el) * 1988-07-21 1992-08-31 Erba Carlo Spa Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
HU208439B (en) * 1988-10-14 1993-10-28 Univ Tulane Process for producing pharmaceutical peptides
US5217955A (en) * 1989-09-15 1993-06-08 Biomeasure, Inc. Treatment of cancer with peptide analog of bombesin, grp, litorin or neuromedin
US5244883A (en) * 1990-11-29 1993-09-14 The Administrators Of The Tulane Educational Fund Nonapeptide bombesin antagonists

Also Published As

Publication number Publication date
FI945378A0 (fi) 1994-11-15
IL108851A0 (en) 1994-06-24
NZ299913A (en) 2000-07-28
RU2114118C1 (ru) 1998-06-27
DE69411342D1 (de) 1998-08-06
RU94046091A (ru) 1996-09-27
CZ280794A3 (en) 1995-07-12
EP0646127A1 (de) 1995-04-05
AU666270B2 (en) 1996-02-01
ES2120615T3 (es) 1998-11-01
EE03180B1 (et) 1999-04-15
KR950701646A (ko) 1995-04-28
NO313418B1 (no) 2002-09-30
IL154995A0 (en) 2003-10-31
SI9420001B (sl) 1999-08-31
ATE167874T1 (de) 1998-07-15
SK282267B6 (sk) 2001-12-03
HRP940164A2 (en) 1996-08-31
NO944293D0 (no) 1994-11-10
US5369094A (en) 1994-11-29
PL180372B1 (pl) 2001-01-31
KR100306506B1 (ko) 2001-12-01
SI9420001A (en) 1995-08-31
PL306209A1 (en) 1995-03-06
ZA941767B (en) 1994-10-06
HUT69727A (en) 1995-09-28
CZ286750B6 (en) 2000-06-14
NZ263668A (en) 1997-06-24
TW325478B (en) 1998-01-21
EP0646127B1 (de) 1998-07-01
BR9404341A (pt) 1999-08-31
HRP940164B1 (en) 2000-02-29
JPH07507330A (ja) 1995-08-10
DK0646127T3 (da) 1999-04-12
UA34456C2 (uk) 2001-03-15
DE69411342T2 (de) 1998-11-19
NO944293L (no) 1995-01-02
SK136494A3 (en) 1995-08-09
WO1994021674A1 (en) 1994-09-29
FI945378A (fi) 1994-11-15
AU6444694A (en) 1994-10-11
CA2135787C (en) 2008-08-12
JP3838656B2 (ja) 2006-10-25
HU218288B (en) 2000-07-28
CA2135787A1 (en) 1994-09-29

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees