ES2017028A6 - Procedimiento para preparar antagonistas de bombesina. - Google Patents
Procedimiento para preparar antagonistas de bombesina.Info
- Publication number
- ES2017028A6 ES2017028A6 ES8902556A ES8902556A ES2017028A6 ES 2017028 A6 ES2017028 A6 ES 2017028A6 ES 8902556 A ES8902556 A ES 8902556A ES 8902556 A ES8902556 A ES 8902556A ES 2017028 A6 ES2017028 A6 ES 2017028A6
- Authority
- ES
- Spain
- Prior art keywords
- leu
- gly
- phe
- ala
- valence bond
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C07K7/086—Bombesin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR ANTAGONISTAS DE BOMBESINA. SE PROPORCIONA UN PROCEDIMIENTO PARA PREPARAR PEPTIDOS DE FORMULA: A-B-C-D-GLN-TRP-ALA-VAL-X-Y-T-W*C *C Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, QUE SE EFECTUA POR UN METODO CLASICO DE DISOLUCION. LOS PEPTIDOS DE LA PRESENTE INVENCION SON ANTAGONISTAS DE BOMBESINA. TAMBIEN SE DESCRIBE LA PREPARACION DE COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888817379A GB8817379D0 (en) | 1988-07-21 | 1988-07-21 | Irreversible peptide ligands for bombesin receptors |
GB898906900A GB8906900D0 (en) | 1989-03-28 | 1989-03-28 | Irreversible peptide ligands for bombesin receptors |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2017028A6 true ES2017028A6 (es) | 1990-12-16 |
Family
ID=26294185
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8902556A Expired - Lifetime ES2017028A6 (es) | 1988-07-21 | 1989-07-19 | Procedimiento para preparar antagonistas de bombesina. |
Country Status (16)
Country | Link |
---|---|
US (1) | US5100873A (es) |
EP (1) | EP0380623B1 (es) |
JP (1) | JPH03500414A (es) |
KR (1) | KR900701829A (es) |
AU (1) | AU619573B2 (es) |
CA (1) | CA1331074C (es) |
DE (1) | DE68909584T2 (es) |
DK (1) | DK71990A (es) |
ES (1) | ES2017028A6 (es) |
FI (1) | FI901369A0 (es) |
GR (1) | GR1000608B (es) |
HU (1) | HU205771B (es) |
IL (1) | IL90997A0 (es) |
NZ (1) | NZ229957A (es) |
PT (1) | PT91215B (es) |
WO (1) | WO1990001037A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5902790A (en) | 1995-10-03 | 1999-05-11 | Cytran, Inc. | Pharmaceutical angiostatic dipeptide compositions and method of use thereof |
JPH04502629A (ja) * | 1989-11-06 | 1992-05-14 | フアルミタリア・カルロ・エルバ・エツセ・エルレ・エルレ | 還元不可逆性ボンベシンアンタゴニスト |
US5767236A (en) * | 1990-05-09 | 1998-06-16 | Biomeasure, Inc. | Linear therapeutic peptides |
US5834433A (en) * | 1990-07-26 | 1998-11-10 | Merrell Pharmaceuticals Inc. | Compounds and pharmaceutical uses of peptides of bombesin and GRP |
US5620959A (en) * | 1990-07-31 | 1997-04-15 | Glaxo Wellcome Inc. | Bombesin antagonists |
US5244883A (en) * | 1990-11-29 | 1993-09-14 | The Administrators Of The Tulane Educational Fund | Nonapeptide bombesin antagonists |
US5369094A (en) * | 1990-11-29 | 1994-11-29 | The Administrators Of The Tulane Educational Fund | Polypeptide bombesin antagonists |
JP3350701B2 (ja) * | 1991-05-23 | 2002-11-25 | メレルダウファーマスーティカルズ インコーポレイテッド | ボンベシン類似体類 |
JPH07505865A (ja) * | 1992-02-07 | 1995-06-29 | メレルダウファーマスーティカルズ インコーポレイテッド | ボンベシンのフェニルアラニン類似体類 |
EP2662087A1 (en) | 2003-04-22 | 2013-11-13 | Ipsen Pharma | Somatostatin vectors |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3792032A (en) * | 1970-07-31 | 1974-02-12 | Farmaceutical Soc | Polypeptides related to the c-terminal heptapeptide of bombesin and alytesin |
US4207311A (en) * | 1977-07-18 | 1980-06-10 | The Salk Institute For Biological Studies | Peptides having analgesic and thermoregulative properties |
US4314999A (en) * | 1978-07-31 | 1982-02-09 | Proter S.P.A. | N-Acyl derivatives of glucosamine having antitumor chemotherapeutic acitivity |
US4540683A (en) * | 1978-07-31 | 1985-09-10 | Proter S.P.A. | In vitro and in vivo treatment of cancer cells and treatment of viruses with a tripeptide compound |
IT1134503B (it) * | 1980-11-28 | 1986-08-13 | Proter Spa | Composti della diclorodietilaminofenilalanina ad azione antitumorale |
US4331661A (en) * | 1980-10-03 | 1982-05-25 | The Salk Institute For Biological Studies | Bombesin analogs |
-
1989
- 1989-06-21 GR GR890100414A patent/GR1000608B/el unknown
- 1989-07-17 IL IL90997A patent/IL90997A0/xx unknown
- 1989-07-17 US US07/380,539 patent/US5100873A/en not_active Expired - Fee Related
- 1989-07-17 NZ NZ229957A patent/NZ229957A/en unknown
- 1989-07-19 HU HU894456A patent/HU205771B/hu unknown
- 1989-07-19 WO PCT/EP1989/000842 patent/WO1990001037A1/en active IP Right Grant
- 1989-07-19 AU AU38788/89A patent/AU619573B2/en not_active Ceased
- 1989-07-19 ES ES8902556A patent/ES2017028A6/es not_active Expired - Lifetime
- 1989-07-19 DE DE89908173T patent/DE68909584T2/de not_active Expired - Fee Related
- 1989-07-19 PT PT91215A patent/PT91215B/pt not_active IP Right Cessation
- 1989-07-19 JP JP1507759A patent/JPH03500414A/ja active Pending
- 1989-07-19 EP EP89908173A patent/EP0380623B1/en not_active Expired - Lifetime
- 1989-07-20 CA CA000606191A patent/CA1331074C/en not_active Expired - Fee Related
-
1990
- 1990-03-19 FI FI901369A patent/FI901369A0/fi not_active IP Right Cessation
- 1990-03-20 DK DK071990A patent/DK71990A/da not_active Application Discontinuation
- 1990-03-20 KR KR1019900700591A patent/KR900701829A/ko active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
PT91215A (pt) | 1990-02-08 |
DK71990D0 (da) | 1990-03-20 |
DE68909584D1 (de) | 1993-11-04 |
DK71990A (da) | 1990-05-21 |
HUT54711A (en) | 1991-03-28 |
WO1990001037A1 (en) | 1990-02-08 |
FI901369A0 (fi) | 1990-03-19 |
NZ229957A (en) | 1991-03-26 |
JPH03500414A (ja) | 1991-01-31 |
HU894456D0 (en) | 1990-12-28 |
PT91215B (pt) | 1995-03-01 |
EP0380623B1 (en) | 1993-09-29 |
AU619573B2 (en) | 1992-01-30 |
GR1000608B (el) | 1992-08-31 |
GR890100414A (en) | 1990-06-27 |
EP0380623A1 (en) | 1990-08-08 |
HU205771B (en) | 1992-06-29 |
AU3878889A (en) | 1990-02-19 |
CA1331074C (en) | 1994-07-26 |
IL90997A0 (en) | 1990-02-09 |
KR900701829A (ko) | 1990-12-04 |
US5100873A (en) | 1992-03-31 |
DE68909584T2 (de) | 1994-03-10 |
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