DK0646127T3 - Polypeptidbombesinantagonister - Google Patents

Polypeptidbombesinantagonister

Info

Publication number
DK0646127T3
DK0646127T3 DK94912199T DK94912199T DK0646127T3 DK 0646127 T3 DK0646127 T3 DK 0646127T3 DK 94912199 T DK94912199 T DK 94912199T DK 94912199 T DK94912199 T DK 94912199T DK 0646127 T3 DK0646127 T3 DK 0646127T3
Authority
DK
Denmark
Prior art keywords
phenyl
alkyl
hydrogen
moiety
10alkyl
Prior art date
Application number
DK94912199T
Other languages
English (en)
Inventor
Andrew Victor Schally
Ren Zhi Cai
Original Assignee
Univ Tulane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tulane filed Critical Univ Tulane
Application granted granted Critical
Publication of DK0646127T3 publication Critical patent/DK0646127T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086Bombesin; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK94912199T 1993-03-15 1994-03-07 Polypeptidbombesinantagonister DK0646127T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/031,325 US5369094A (en) 1990-11-29 1993-03-15 Polypeptide bombesin antagonists
PCT/US1994/002511 WO1994021674A1 (en) 1993-03-15 1994-03-07 Polypeptide bombesin antagonists

Publications (1)

Publication Number Publication Date
DK0646127T3 true DK0646127T3 (da) 1999-04-12

Family

ID=21858823

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94912199T DK0646127T3 (da) 1993-03-15 1994-03-07 Polypeptidbombesinantagonister

Country Status (27)

Country Link
US (1) US5369094A (da)
EP (1) EP0646127B1 (da)
JP (1) JP3838656B2 (da)
KR (1) KR100306506B1 (da)
AT (1) ATE167874T1 (da)
AU (1) AU666270B2 (da)
BR (1) BR9404341A (da)
CA (1) CA2135787C (da)
CZ (1) CZ286750B6 (da)
DE (1) DE69411342T2 (da)
DK (1) DK0646127T3 (da)
EE (1) EE03180B1 (da)
ES (1) ES2120615T3 (da)
FI (1) FI945378A0 (da)
HR (1) HRP940164B1 (da)
HU (1) HU218288B (da)
IL (2) IL108851A (da)
NO (1) NO313418B1 (da)
NZ (2) NZ299913A (da)
PL (1) PL180372B1 (da)
RU (1) RU2114118C1 (da)
SI (1) SI9420001B (da)
SK (1) SK282267B6 (da)
TW (1) TW325478B (da)
UA (1) UA34456C2 (da)
WO (1) WO1994021674A1 (da)
ZA (1) ZA941767B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877277A (en) 1987-09-24 1999-03-02 Biomeasure, Inc. Octapeptide bombesin analogs
US5723578A (en) * 1987-09-24 1998-03-03 The Administrators Of Tulane Educational Fund Peptide analogs of bombesin
US5650395A (en) * 1995-03-13 1997-07-22 Hurel; Steven Treatment of pulmonary hypertension
US6989371B1 (en) 1996-08-16 2006-01-24 Dabur Research Foundation Bombesin analogs for treatment of cancer
DE69840647D1 (de) 1997-04-22 2009-04-23 Curator Of The University Of M Konjugate aus peptiden, die liganden von gastrinrezeptoren sind
EP1333829A1 (en) * 2000-11-17 2003-08-13 Warner-Lambert Company LLC Treatment of sexual dysfunction using bombesin antagonists
US7850947B2 (en) * 2003-01-13 2010-12-14 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7922998B2 (en) * 2003-01-13 2011-04-12 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7989417B2 (en) * 2003-01-13 2011-08-02 Bracco Imaging S.P.A. Linkers for radiopharmaceutical compounds
US7226577B2 (en) * 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
US20060239923A1 (en) * 2003-01-13 2006-10-26 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US8420050B2 (en) * 2003-01-13 2013-04-16 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7611692B2 (en) 2003-01-13 2009-11-03 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
WO2004093807A2 (en) 2003-04-22 2004-11-04 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Somatostatin vectors
US7795385B2 (en) * 2004-12-17 2010-09-14 Bexar Global, Inc. Use of bombesin/gastrin-releasing peptide antagonists for the treatment of inflammatory conditions, acute lung injury and bipolar disorder
FR2918566B1 (fr) * 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
EP2100900A1 (en) * 2008-03-07 2009-09-16 Universitätsspital Basel Bombesin analog peptide antagonist conjugates
EP2198878A1 (en) * 2008-12-18 2010-06-23 University Of Miami Polypeptide bombesin antagonists
JP2013507364A (ja) 2009-10-07 2013-03-04 メルク・シャープ・エンド・ドーム・コーポレイション 新規なtrpa1アンタゴニスト

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162497A (en) * 1987-09-24 1992-11-10 The Administrators Of The Tulane Educational Fund Bradykinin analogs with non-peptide bond
JP2795449B2 (ja) * 1987-09-24 1998-09-10 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 治療用ペプチド
US5084555A (en) * 1989-08-21 1992-01-28 The Administrators Of The Tulane Educational Fund An octapeptide bombesin analog
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
GB8813356D0 (en) * 1988-06-06 1988-07-13 Ici Plc Polypeptide compounds
GR1000608B (el) * 1988-07-21 1992-08-31 Erba Carlo Spa Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
ATE165836T1 (de) * 1988-10-14 1998-05-15 Univ Tulane Peptide als arzneimittel
US5217955A (en) * 1989-09-15 1993-06-08 Biomeasure, Inc. Treatment of cancer with peptide analog of bombesin, grp, litorin or neuromedin
US5244883A (en) * 1990-11-29 1993-09-14 The Administrators Of The Tulane Educational Fund Nonapeptide bombesin antagonists

Also Published As

Publication number Publication date
PL306209A1 (en) 1995-03-06
SI9420001B (sl) 1999-08-31
CZ280794A3 (en) 1995-07-12
FI945378A (fi) 1994-11-15
NO944293L (no) 1995-01-02
RU94046091A (ru) 1996-09-27
JPH07507330A (ja) 1995-08-10
KR950701646A (ko) 1995-04-28
SK136494A3 (en) 1995-08-09
IL154995A0 (en) 2003-10-31
NO944293D0 (no) 1994-11-10
WO1994021674A1 (en) 1994-09-29
EP0646127B1 (en) 1998-07-01
EP0646127A1 (en) 1995-04-05
HU218288B (en) 2000-07-28
ES2120615T3 (es) 1998-11-01
RU2114118C1 (ru) 1998-06-27
DE69411342T2 (de) 1998-11-19
CZ286750B6 (en) 2000-06-14
CA2135787C (en) 2008-08-12
HUT69727A (en) 1995-09-28
ATE167874T1 (de) 1998-07-15
US5369094A (en) 1994-11-29
CA2135787A1 (en) 1994-09-29
NZ299913A (en) 2000-07-28
ZA941767B (en) 1994-10-06
SK282267B6 (sk) 2001-12-03
NZ263668A (en) 1997-06-24
SI9420001A (en) 1995-08-31
DE69411342D1 (de) 1998-08-06
EE03180B1 (et) 1999-04-15
NO313418B1 (no) 2002-09-30
PL180372B1 (pl) 2001-01-31
JP3838656B2 (ja) 2006-10-25
BR9404341A (pt) 1999-08-31
TW325478B (en) 1998-01-21
IL108851A0 (en) 1994-06-24
FI945378A0 (fi) 1994-11-15
HRP940164B1 (en) 2000-02-29
HRP940164A2 (en) 1996-08-31
IL108851A (en) 2003-05-29
AU6444694A (en) 1994-10-11
UA34456C2 (uk) 2001-03-15
KR100306506B1 (ko) 2001-12-01
AU666270B2 (en) 1996-02-01

Similar Documents

Publication Publication Date Title
DK0646127T3 (da) Polypeptidbombesinantagonister
CA2097192A1 (en) Bombesin antagonists
HUP0003592A2 (hu) LH-RH peptid analógok, alkalmazásuk, és ezeket tartalmazó gyógyászati készítmények
GB1533077A (en) 4-substituted enkephalin derivatives
ES460618A1 (es) Procedimiento para la preparacion de derivados de peptido
GB1526367A (en) Polypeptide
DE3751398T2 (de) Substrat-Peptide.
GB1224576A (en) Novel tetrapeptide amides and the preparation thereof
ES416516A1 (es) Un procedimiento para la preparacion de nonapeptidos.
GB1363801A (en) Peptides and their preparation
GB1273873A (en) Corticotropically highly active octadecapeptides
GB1329869A (en) Tetracycline derivatives
ES248724A1 (es) Procedimiento para la obtenciën de nuevosdecapeptures ciclicos
GB1224658A (en) Cyclic decapeptides
TH17064B (th) ตัวปฏิปักษ์ต่อโปลีเปปไทด์บอมเบซิน
FR4219M (da)
GB1039536A (en) Manufacture of highly active isomers of hypertensin ó and of its analogues