TW325478B - Polypeptide bombesin antagonists - Google Patents

Polypeptide bombesin antagonists

Info

Publication number
TW325478B
TW325478B TW083101048A TW83101048A TW325478B TW 325478 B TW325478 B TW 325478B TW 083101048 A TW083101048 A TW 083101048A TW 83101048 A TW83101048 A TW 83101048A TW 325478 B TW325478 B TW 325478B
Authority
TW
Taiwan
Prior art keywords
moiety
glu
leu
group
alpha amino
Prior art date
Application number
TW083101048A
Other languages
English (en)
Inventor
V Schally Andrew
Zhi Cai Ren
Original Assignee
Asministrators Of The Tulane Educational Fund
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asministrators Of The Tulane Educational Fund filed Critical Asministrators Of The Tulane Educational Fund
Application granted granted Critical
Publication of TW325478B publication Critical patent/TW325478B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086—Bombesin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
TW083101048A 1993-03-15 1994-02-23 Polypeptide bombesin antagonists TW325478B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/031,325 US5369094A (en) 1990-11-29 1993-03-15 Polypeptide bombesin antagonists

Publications (1)

Publication Number Publication Date
TW325478B true TW325478B (en) 1998-01-21

Family

ID=21858823

Family Applications (1)

Application Number Title Priority Date Filing Date
TW083101048A TW325478B (en) 1993-03-15 1994-02-23 Polypeptide bombesin antagonists

Country Status (27)

Country Link
US (1) US5369094A (zh)
EP (1) EP0646127B1 (zh)
JP (1) JP3838656B2 (zh)
KR (1) KR100306506B1 (zh)
AT (1) ATE167874T1 (zh)
AU (1) AU666270B2 (zh)
BR (1) BR9404341A (zh)
CA (1) CA2135787C (zh)
CZ (1) CZ286750B6 (zh)
DE (1) DE69411342T2 (zh)
DK (1) DK0646127T3 (zh)
EE (1) EE03180B1 (zh)
ES (1) ES2120615T3 (zh)
FI (1) FI945378A (zh)
HR (1) HRP940164B1 (zh)
HU (1) HU218288B (zh)
IL (2) IL108851A (zh)
NO (1) NO313418B1 (zh)
NZ (2) NZ299913A (zh)
PL (1) PL180372B1 (zh)
RU (1) RU2114118C1 (zh)
SI (1) SI9420001B (zh)
SK (1) SK282267B6 (zh)
TW (1) TW325478B (zh)
UA (1) UA34456C2 (zh)
WO (1) WO1994021674A1 (zh)
ZA (1) ZA941767B (zh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723578A (en) * 1987-09-24 1998-03-03 The Administrators Of Tulane Educational Fund Peptide analogs of bombesin
US5877277A (en) 1987-09-24 1999-03-02 Biomeasure, Inc. Octapeptide bombesin analogs
US5650395A (en) * 1995-03-13 1997-07-22 Hurel; Steven Treatment of pulmonary hypertension
US6989371B1 (en) 1996-08-16 2006-01-24 Dabur Research Foundation Bombesin analogs for treatment of cancer
JP2002506424A (ja) 1997-04-22 2002-02-26 キュレイター オブ ザ ユニバーシィティ オブ ミズーリ ガストリン受容体−親和性ペプチド結合体
IL155814A0 (en) * 2000-11-17 2003-12-23 Warner Lambert Co Treatment of sexual dysfunction using bombesin antagonist
US8420050B2 (en) * 2003-01-13 2013-04-16 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7226577B2 (en) * 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
US7611692B2 (en) 2003-01-13 2009-11-03 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US20060239923A1 (en) * 2003-01-13 2006-10-26 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
ATE435035T1 (de) * 2003-01-13 2009-07-15 Bracco Imaging Spa Verbesserte linker für radiopharmazeutische verbindungen
US7850947B2 (en) 2003-01-13 2010-12-14 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7922998B2 (en) * 2003-01-13 2011-04-12 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
CN1777439A (zh) 2003-04-22 2006-05-24 研究及应用科学协会股份有限公司 生长抑素的载体
US7795385B2 (en) * 2004-12-17 2010-09-14 Bexar Global, Inc. Use of bombesin/gastrin-releasing peptide antagonists for the treatment of inflammatory conditions, acute lung injury and bipolar disorder
FR2918566B1 (fr) * 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
EP2100900A1 (en) * 2008-03-07 2009-09-16 Universitätsspital Basel Bombesin analog peptide antagonist conjugates
EP2198878A1 (en) * 2008-12-18 2010-06-23 University Of Miami Polypeptide bombesin antagonists
AU2010303822A1 (en) 2009-10-07 2012-03-15 Merck Sharp & Dohme Corp. Novel TRPA1 antagonists

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2795449B2 (ja) * 1987-09-24 1998-09-10 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 治療用ペプチド
US5162497A (en) * 1987-09-24 1992-11-10 The Administrators Of The Tulane Educational Fund Bradykinin analogs with non-peptide bond
US5084555A (en) * 1989-08-21 1992-01-28 The Administrators Of The Tulane Educational Fund An octapeptide bombesin analog
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
GB8813356D0 (en) * 1988-06-06 1988-07-13 Ici Plc Polypeptide compounds
GR1000608B (el) * 1988-07-21 1992-08-31 Erba Carlo Spa Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
WO1990003980A1 (en) * 1988-10-14 1990-04-19 Administrators Of The Tulane Educational Fund Therapeutic peptides
US5217955A (en) * 1989-09-15 1993-06-08 Biomeasure, Inc. Treatment of cancer with peptide analog of bombesin, grp, litorin or neuromedin
US5244883A (en) * 1990-11-29 1993-09-14 The Administrators Of The Tulane Educational Fund Nonapeptide bombesin antagonists

Also Published As

Publication number Publication date
PL306209A1 (en) 1995-03-06
RU94046091A (ru) 1996-09-27
NO944293D0 (no) 1994-11-10
HUT69727A (en) 1995-09-28
JPH07507330A (ja) 1995-08-10
CZ280794A3 (en) 1995-07-12
JP3838656B2 (ja) 2006-10-25
EP0646127B1 (en) 1998-07-01
HRP940164A2 (en) 1996-08-31
CA2135787A1 (en) 1994-09-29
KR950701646A (ko) 1995-04-28
EE03180B1 (et) 1999-04-15
IL108851A (en) 2003-05-29
NO313418B1 (no) 2002-09-30
BR9404341A (pt) 1999-08-31
ES2120615T3 (es) 1998-11-01
ATE167874T1 (de) 1998-07-15
SK136494A3 (en) 1995-08-09
DE69411342T2 (de) 1998-11-19
US5369094A (en) 1994-11-29
NO944293L (no) 1995-01-02
UA34456C2 (uk) 2001-03-15
SI9420001A (en) 1995-08-31
IL154995A0 (en) 2003-10-31
AU6444694A (en) 1994-10-11
CA2135787C (en) 2008-08-12
HU218288B (en) 2000-07-28
PL180372B1 (pl) 2001-01-31
AU666270B2 (en) 1996-02-01
EP0646127A1 (en) 1995-04-05
SK282267B6 (sk) 2001-12-03
FI945378A0 (fi) 1994-11-15
SI9420001B (sl) 1999-08-31
IL108851A0 (en) 1994-06-24
NZ299913A (en) 2000-07-28
FI945378A (fi) 1994-11-15
DK0646127T3 (da) 1999-04-12
WO1994021674A1 (en) 1994-09-29
ZA941767B (en) 1994-10-06
CZ286750B6 (en) 2000-06-14
KR100306506B1 (ko) 2001-12-01
RU2114118C1 (ru) 1998-06-27
HRP940164B1 (en) 2000-02-29
NZ263668A (en) 1997-06-24
DE69411342D1 (de) 1998-08-06

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees