IL107755A - Kit and pharmaceutical compositions comprising a combination of 2-¬4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone and proguanil for the treatment and prophylaxis of parasitic infections - Google Patents

Kit and pharmaceutical compositions comprising a combination of 2-¬4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone and proguanil for the treatment and prophylaxis of parasitic infections

Info

Publication number
IL107755A
IL107755A IL10775593A IL10775593A IL107755A IL 107755 A IL107755 A IL 107755A IL 10775593 A IL10775593 A IL 10775593A IL 10775593 A IL10775593 A IL 10775593A IL 107755 A IL107755 A IL 107755A
Authority
IL
Israel
Prior art keywords
proguanil
naphthoquinone
prophylaxis
chlorophenyl
cyclohexyl
Prior art date
Application number
IL10775593A
Other languages
English (en)
Other versions
IL107755A0 (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10725687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL107755(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IL107755A0 publication Critical patent/IL107755A0/xx
Publication of IL107755A publication Critical patent/IL107755A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL10775593A 1992-11-26 1993-11-25 Kit and pharmaceutical compositions comprising a combination of 2-¬4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone and proguanil for the treatment and prophylaxis of parasitic infections IL107755A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929224739A GB9224739D0 (en) 1992-11-26 1992-11-26 Medicaments

Publications (2)

Publication Number Publication Date
IL107755A0 IL107755A0 (en) 1994-02-27
IL107755A true IL107755A (en) 2000-10-31

Family

ID=10725687

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10775593A IL107755A (en) 1992-11-26 1993-11-25 Kit and pharmaceutical compositions comprising a combination of 2-¬4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone and proguanil for the treatment and prophylaxis of parasitic infections

Country Status (38)

Country Link
US (3) US5998449A (zh)
EP (1) EP0670719B1 (zh)
JP (1) JP3768231B2 (zh)
KR (1) KR100294802B1 (zh)
CN (1) CN1087935C (zh)
AP (1) AP517A (zh)
AT (1) ATE191340T1 (zh)
AU (1) AU685408B2 (zh)
BG (1) BG62595B1 (zh)
CA (1) CA2150234E (zh)
CY (1) CY2193B1 (zh)
CZ (2) CZ289171B6 (zh)
DE (1) DE69328307T2 (zh)
DK (1) DK0670719T3 (zh)
ES (1) ES2145114T3 (zh)
GB (1) GB9224739D0 (zh)
GR (1) GR3033745T3 (zh)
HK (1) HK1004468A1 (zh)
HU (1) HU225918B1 (zh)
IL (1) IL107755A (zh)
MX (1) MX9307402A (zh)
MY (1) MY114241A (zh)
NO (1) NO313225B1 (zh)
NZ (1) NZ257901A (zh)
OA (1) OA10352A (zh)
PE (1) PE55694A1 (zh)
PL (1) PL174323B1 (zh)
PT (1) PT670719E (zh)
RO (1) RO119280B1 (zh)
RU (1) RU2108092C1 (zh)
SA (1) SA93140434B1 (zh)
SG (1) SG45387A1 (zh)
SI (1) SI9300614A (zh)
SK (1) SK281559B6 (zh)
TW (1) TW253835B (zh)
UA (1) UA45948C2 (zh)
WO (1) WO1994012164A1 (zh)
ZA (1) ZA938832B (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9224739D0 (en) * 1992-11-26 1993-01-13 Wellcome Found Medicaments
GB9424013D0 (en) * 1994-11-29 1995-01-18 Wellcome Found Medicaments
DE19737463A1 (de) * 1997-08-28 1999-03-04 Hoechst Marion Roussel De Gmbh Verwendung von Inhibitoren des Natrium-Wasserstoff-Austauschers zur Herstellung eines Arzneimittels zur Behandlung von Erkrankungen, die durch Protozoen verursacht werden
GB9822681D0 (en) * 1998-10-16 1998-12-09 Vitabiotics Ltd Method of treatment
ES2199817T3 (es) * 1999-04-09 2004-03-01 Glaxo Group Limited Preparacion combinada para tratar la malaria.
US7104076B2 (en) * 2004-06-24 2006-09-12 Carrier Corporation Lubricant return schemes for use in refrigerant cycle
ITMI20070941A1 (it) * 2007-05-09 2008-11-10 Chimico Internazi0Nale S P A L Procedimento per la preparazione di naftochinoni trans2,3-disostituiti
WO2011021230A2 (en) * 2009-08-20 2011-02-24 Ipca Laboratories Limited Novel complex for treatment and/or prophylaxis of parasitic infections
US20180055835A1 (en) 2016-08-25 2018-03-01 Immune Therapeutics Inc. Method for Treating And Preventing Protozoal Infections

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2533648A (en) * 1949-03-05 1950-12-12 Joseph H Warburg Circular saw making
NL6411993A (zh) * 1963-10-18 1965-04-20
US3347830A (en) * 1964-07-30 1967-10-17 Grace W R & Co Process of polymerizing formaldehyde
GB1141735A (en) * 1966-11-23 1969-01-29 Pfizer & Co C Pharmaceutical anti-tumor composition
NL6817526A (zh) * 1968-01-24 1969-07-28
US3655699A (en) * 1970-03-02 1972-04-11 Pfizer Analogues of lapachol as antitumor agents
DE2601458A1 (de) * 1975-01-20 1976-07-22 Ciba Geigy Ag Loesliche, von phenylindandiaminen abgeleitete polyamide
JPS5492945A (en) * 1977-11-22 1979-07-23 Wellcome Found Naphthoquinone derivative
US4485116A (en) * 1981-10-16 1984-11-27 Hudson Alan T Antiprotozoal compounds
US4485117A (en) * 1981-10-16 1984-11-27 Hudson Alan T Antiprotozoal compounds
GB8310140D0 (en) * 1983-04-14 1983-05-18 Wellcome Found Antiprotozoal agents
US5053432A (en) * 1983-04-14 1991-10-01 Burroughs Wellcome Co. Naphthoquinone derivatives
GB8310141D0 (en) * 1983-04-14 1983-05-18 Wellcome Found Naphthoquinone derivatives
JPS59196467A (ja) * 1983-04-23 1984-11-07 Nissan Motor Co Ltd 車輪速及びまたは車輪加減速度検出方法
US5225184A (en) * 1988-08-16 1993-07-06 Burroughs Wellcome Co. Medicaments
GB8819477D0 (en) * 1988-08-16 1988-09-21 Wellcome Found Medicaments
ATE178311T1 (de) * 1988-08-16 1999-04-15 Wellcome Found Neue naphthochinone und ihre anwendung als arzneimittel
US5206268A (en) * 1988-08-16 1993-04-27 Burroughs Wellcome Co. Medicaments
GB8921516D0 (en) * 1989-09-22 1989-11-08 Wellcome Found Medicaments
GB8923254D0 (en) * 1989-10-16 1989-12-06 Wellcome Found Medicaments
US5014737A (en) * 1989-11-13 1991-05-14 Allan Berman Quartz integrated trough/sump recirculating filtered high-purity chemical bath
GB9121316D0 (en) * 1991-10-09 1991-11-20 Wellcome Found Heterocyclic compounds
GB9224739D0 (en) * 1992-11-26 1993-01-13 Wellcome Found Medicaments
GB9226905D0 (en) * 1992-12-24 1993-02-17 Wellcome Found Pharmaceutical preparation
ATE143601T1 (de) * 1993-05-05 1996-10-15 Palo Alto Medical Found Verwendung von rifamycinderivaten zur herstellung eines arzneimittels zur behandlung der toxoplasmose
US5529994A (en) * 1993-05-05 1996-06-25 Palo Alto Medical Foundation Treatment for toxoplasmosis
US5733932A (en) * 1995-01-06 1998-03-31 The Picower Institute For Medical Research Compounds and methods of use to derivatize neighboring lysine residues in proteins under physiological conditions
US5827543A (en) * 1995-12-07 1998-10-27 The Procter & Gamble Company Methods and compositions for the prevention and treatment of urogenital disorders
US5744168A (en) * 1995-12-07 1998-04-28 The Procter & Gamble Company Methods and compositions for the prevention and treatment of gastrointestinal disorders
US5747476A (en) * 1996-07-17 1998-05-05 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoal myeloencephalitis
ZA983331B (en) * 1997-05-01 1998-10-27 Allegheny University Of The He Method for treating protozoal infections
AUPO821097A0 (en) * 1997-07-25 1997-08-14 Cultor Ltd. A prophylactic
DE19737463A1 (de) * 1997-08-28 1999-03-04 Hoechst Marion Roussel De Gmbh Verwendung von Inhibitoren des Natrium-Wasserstoff-Austauschers zur Herstellung eines Arzneimittels zur Behandlung von Erkrankungen, die durch Protozoen verursacht werden
ES2199817T3 (es) * 1999-04-09 2004-03-01 Glaxo Group Limited Preparacion combinada para tratar la malaria.

Also Published As

Publication number Publication date
US5998449A (en) 1999-12-07
CN1087935C (zh) 2002-07-24
AP9300592A0 (en) 1994-01-31
ATE191340T1 (de) 2000-04-15
SK281559B6 (sk) 2001-05-10
CA2150234E (en) 2005-03-22
GB9224739D0 (en) 1993-01-13
HU9501537D0 (en) 1995-07-28
BG62595B1 (bg) 2000-03-31
SA93140434B1 (ar) 2004-09-01
PL174323B1 (pl) 1998-07-31
CZ289692B6 (cs) 2002-03-13
HU225918B1 (en) 2007-12-28
DK0670719T3 (da) 2000-07-31
CZ289171B6 (cs) 2001-11-14
TW253835B (zh) 1995-08-11
EP0670719A1 (en) 1995-09-13
HUT71346A (en) 1995-11-28
NO951995D0 (no) 1995-05-19
AU685408B2 (en) 1998-01-22
DE69328307T2 (de) 2000-10-26
CN1091632A (zh) 1994-09-07
KR100294802B1 (ko) 2001-09-17
AP517A (en) 1996-08-23
RU2108092C1 (ru) 1998-04-10
CA2150234A1 (en) 1994-06-09
PE55694A1 (es) 1995-01-25
PT670719E (pt) 2000-09-29
GR3033745T3 (en) 2000-10-31
US6291488B1 (en) 2001-09-18
NO313225B1 (no) 2002-09-02
PL309222A1 (en) 1995-10-02
NZ257901A (en) 1997-01-29
WO1994012164A1 (en) 1994-06-09
BG99656A (bg) 1996-04-30
SK57095A3 (en) 1996-05-08
MY114241A (en) 2002-09-30
DE69328307D1 (de) 2000-05-11
ZA938832B (en) 1995-05-25
IL107755A0 (en) 1994-02-27
NO951995L (no) 1995-07-03
SI9300614A (en) 1994-06-30
US6166046A (en) 2000-12-26
UA45948C2 (uk) 2002-05-15
SG45387A1 (en) 1998-01-16
RO119280B1 (ro) 2004-07-30
HK1004468A1 (en) 1998-11-27
AU5532294A (en) 1994-06-22
JPH08503938A (ja) 1996-04-30
CY2193B1 (en) 2002-11-08
ES2145114T3 (es) 2000-07-01
MX9307402A (es) 1994-07-29
CZ119295A3 (en) 1995-11-15
EP0670719B1 (en) 2000-04-05
OA10352A (en) 2001-10-22
CA2150234C (en) 2001-01-16
JP3768231B2 (ja) 2006-04-19

Similar Documents

Publication Publication Date Title
UA29398C2 (uk) Антимікробний перкислотний склад (варіанти)
AU3462993A (en) Remedy for dermatopathy and metallothionein inducer
ZA947305B (en) Pharmaceutical compositions and usages
EP0744945A4 (en) ANTIMICROBIAL SURFACE CLEANER CONTAINING CHLORHEXIDING GLUCONATE AND ALCOHOL
HRP20030046A2 (en) Pharmaceutical compositions for the treatment of mucositis, stomatitis and behcet's syndrome
AU3684293A (en) Disinfectant compositions
ZA948779B (en) Non-irritating cosmetic compositions
AU8744491A (en) Agents effecting the lysis of oral bacteria
AU685933B2 (en) Oxime derivative and bactericide containing the same as active ingredient
IL107755A (en) Kit and pharmaceutical compositions comprising a combination of 2-¬4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone and proguanil for the treatment and prophylaxis of parasitic infections
AU1792492A (en) Phellodendrine analogs and allergy type iv suppressor containing the same as active ingredient
EP0727990A4 (en) CONNECTIONS, PREPARATIONS AND TREATMENT OF ALLERGIES AND IGNITIONS
AU2807492A (en) Use of misoprostol for the treatment of allergy
EP0722322A4 (en) CONNECTIONS AND COMPOSITIONS FOR THE TREATMENT OF ALLERGIES AND IGNITIONS
AU2194592A (en) Linear hydroxamates, their preparation and pharmaceutical compositions comprising them for treatment of iron and aluminium overload
AU662651B2 (en) Sulfamoyltriazole derivative and bactericide containing the same as active ingredient
AU2299592A (en) Treatment of periodontal disease with protease inhibitors
HU9403128D0 (en) Pharmaceutical compositions against flavivirus infections containing heteropolytungstates
AU1240295A (en) Pharmaceutical composition for immunomodulating and adjuvant treatment
AU6130194A (en) 1,2-dithiole-3-thiones for the treatment of reverse transcriptase-dependent viral infections
HU9303246D0 (en) Pharmaceutical compositions containing purpurogallin as antioxidant and citoprotective agent
GB9304745D0 (en) Use of pharmaceutical formulations
AU7209394A (en) Gallium complexes for the treatment of free radical-induced diseases
ITBZ930026A0 (it) Procedimento per la movimentazione traslatoria di componenti ed azio- natore di movimento per l'attuazione del procedimento.
EP0502470A3 (en) Compounds for the treatment of inflammation and allergy

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired