AU2299592A - Treatment of periodontal disease with protease inhibitors - Google Patents

Treatment of periodontal disease with protease inhibitors

Info

Publication number
AU2299592A
AU2299592A AU22995/92A AU2299592A AU2299592A AU 2299592 A AU2299592 A AU 2299592A AU 22995/92 A AU22995/92 A AU 22995/92A AU 2299592 A AU2299592 A AU 2299592A AU 2299592 A AU2299592 A AU 2299592A
Authority
AU
Australia
Prior art keywords
treatment
protease inhibitors
periodontal disease
periodontal
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU22995/92A
Inventor
Michael A Curtis
Philip A Pemberton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Childrens Medical Center Corp
Original Assignee
Childrens Medical Center Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Medical Center Corp filed Critical Childrens Medical Center Corp
Publication of AU2299592A publication Critical patent/AU2299592A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8128—Antithrombin III
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G01N2333/8125—Alpha-1-antitrypsin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G01N2333/8128—Antithrombin III

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU22995/92A 1991-07-02 1992-07-01 Treatment of periodontal disease with protease inhibitors Abandoned AU2299592A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72482391A 1991-07-02 1991-07-02
US724823 1991-07-02

Publications (1)

Publication Number Publication Date
AU2299592A true AU2299592A (en) 1993-02-11

Family

ID=24912061

Family Applications (1)

Application Number Title Priority Date Filing Date
AU22995/92A Abandoned AU2299592A (en) 1991-07-02 1992-07-01 Treatment of periodontal disease with protease inhibitors

Country Status (2)

Country Link
AU (1) AU2299592A (en)
WO (1) WO1993000926A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1005193C2 (en) * 1997-02-05 1998-08-06 Biodent B V Compositions containing plant-derived protease inhibitors
JPH1160500A (en) * 1997-08-11 1999-03-02 Nippon Chem Res Kk Blood coagulation abnormal advance inhibitor
FR2794771B1 (en) 1999-06-11 2001-08-10 Aventis Pharma Sa RECOMBINANT ADENOVIRUSES ENCODING THE IODINE SPECIFIC TRANSPORTER (NIS)
AUPQ380699A0 (en) * 1999-11-02 1999-11-25 Biotech Australia Pty Limited Protease inhibitors as modulators of periodontal wound healing
EP3204352B1 (en) 2014-10-06 2020-07-01 Cortexyme, Inc. Inhibitors of lysine gingipain
EP3374352A4 (en) 2015-11-09 2019-10-02 Cortexyme, Inc. Inhibitors of arginine gingipain
CA3036862A1 (en) 2016-09-16 2018-03-22 Cortexyme, Inc. Ketone inhibitors of lysine gingipain

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59152309A (en) * 1983-02-18 1984-08-31 Sunstar Inc Oral cavity composition
EP0255341B1 (en) * 1986-07-29 1993-02-03 Sunstar Kabushiki Kaisha Reagent for testing periodontal diseases
ATE154362T1 (en) * 1989-09-05 1997-06-15 Biotech Australia Pty Ltd METHOD FOR PRODUCING PAI-2

Also Published As

Publication number Publication date
WO1993000926A1 (en) 1993-01-21

Similar Documents

Publication Publication Date Title
HU9303218D0 (en) Application of atp-depended protease and its inhibitor for treatment of cachexy and amyotrophia
AU3462993A (en) Remedy for dermatopathy and metallothionein inducer
AU4084193A (en) Toothbrush
AU3888793A (en) Novel medicament
AU1504892A (en) Toothbrush
AU1954392A (en) Inhibitors of hiv protease useful for the treatment of aids
FI943234A0 (en) Human Kunitzt type protease inhibitor variant
AU1960488A (en) Cysteine proteinase inhibitor
AU2675988A (en) Surfactant inhibition of dental plaque
AU6801694A (en) The treatment of small animals
AU4524889A (en) Method for the treatment of periodontal disease
AU3007492A (en) Treatment of wastewater
AU659456B2 (en) Fatty acid treatment
AU2251892A (en) Inhibitors of picornavirus proteases
AU3328693A (en) Treatment of fungal infections
AU2807492A (en) Use of misoprostol for the treatment of allergy
AU2299592A (en) Treatment of periodontal disease with protease inhibitors
AU5426994A (en) Toothbrush
AU656027B2 (en) Saccharin derivative proteolytic enzime inhibitors
AU1279788A (en) Compounds and treatment
AU3553489A (en) Novel compounds and treatment
AU2919192A (en) Piece of jewellery
AU4220193A (en) Deazaaminopterins for treatment of inflammation
AU3641993A (en) Treatment chamber
AU4680393A (en) Disposable toothbrush