IE59098B1 - Piperazinecarboxylic acid, its preparation and pharmaceutical compositions containing it - Google Patents

Piperazinecarboxylic acid, its preparation and pharmaceutical compositions containing it

Info

Publication number
IE59098B1
IE59098B1 IE41388A IE41388A IE59098B1 IE 59098 B1 IE59098 B1 IE 59098B1 IE 41388 A IE41388 A IE 41388A IE 41388 A IE41388 A IE 41388A IE 59098 B1 IE59098 B1 IE 59098B1
Authority
IE
Ireland
Prior art keywords
compound
formula
treatment
monohydrate
salt
Prior art date
Application number
IE41388A
Other languages
English (en)
Other versions
IE880413L (en
Inventor
Bernhard Aebischer
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of IE880413L publication Critical patent/IE880413L/xx
Publication of IE59098B1 publication Critical patent/IE59098B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IE41388A 1987-02-18 1988-02-16 Piperazinecarboxylic acid, its preparation and pharmaceutical compositions containing it IE59098B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878703749A GB8703749D0 (en) 1987-02-18 1987-02-18 Piperazinecarboxylic acid

Publications (2)

Publication Number Publication Date
IE880413L IE880413L (en) 1988-08-18
IE59098B1 true IE59098B1 (en) 1994-01-12

Family

ID=10612501

Family Applications (1)

Application Number Title Priority Date Filing Date
IE41388A IE59098B1 (en) 1987-02-18 1988-02-16 Piperazinecarboxylic acid, its preparation and pharmaceutical compositions containing it

Country Status (28)

Country Link
JP (1) JPH0723387B2 (enrdf_load_stackoverflow)
KR (1) KR960015190B1 (enrdf_load_stackoverflow)
AT (1) AT391320B (enrdf_load_stackoverflow)
AU (1) AU613009B2 (enrdf_load_stackoverflow)
BE (1) BE1002427A3 (enrdf_load_stackoverflow)
CA (1) CA1327799C (enrdf_load_stackoverflow)
CH (1) CH675125A5 (enrdf_load_stackoverflow)
CY (1) CY1739A (enrdf_load_stackoverflow)
DE (1) DE3804936C2 (enrdf_load_stackoverflow)
DK (1) DK168441B1 (enrdf_load_stackoverflow)
ES (2) ES2011319A6 (enrdf_load_stackoverflow)
FI (1) FI86733C (enrdf_load_stackoverflow)
FR (1) FR2610932B1 (enrdf_load_stackoverflow)
GB (2) GB8703749D0 (enrdf_load_stackoverflow)
GR (1) GR1002471B (enrdf_load_stackoverflow)
HK (1) HK142093A (enrdf_load_stackoverflow)
HU (2) HU199858B (enrdf_load_stackoverflow)
IE (1) IE59098B1 (enrdf_load_stackoverflow)
IL (1) IL85436A0 (enrdf_load_stackoverflow)
IT (1) IT1219447B (enrdf_load_stackoverflow)
LU (1) LU87129A1 (enrdf_load_stackoverflow)
MY (1) MY103206A (enrdf_load_stackoverflow)
NL (1) NL8800412A (enrdf_load_stackoverflow)
NZ (1) NZ223529A (enrdf_load_stackoverflow)
PH (1) PH25512A (enrdf_load_stackoverflow)
PT (1) PT86776B (enrdf_load_stackoverflow)
SE (1) SE467256B (enrdf_load_stackoverflow)
ZA (1) ZA881146B (enrdf_load_stackoverflow)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU202111B (en) * 1988-03-11 1991-02-28 Sandoz Ag Process for producing pharmaceutical compositions containing (r)-(e)-4--(3-phosphono-2-propenyl)-2-piperazine-carboxylic acid as active component
US5086072A (en) * 1990-06-18 1992-02-04 The United States Of America As Represented By The Department Of Health And Human Services Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex
EP0488959A3 (en) * 1990-11-28 1992-08-05 Sandoz Ltd. New uses of competitive nmda receptor antagonists
US5260286A (en) * 1992-10-16 1993-11-09 Japan Tobacco, Inc. 2-piperidinecarboxylic acid derivatives useful as NMDA receptor antagonists
EP0826032A1 (de) * 1995-05-08 1998-03-04 Lonza Ag Biotechnologisches verfahren zur herstellung von r-alpha-piperazincarbonsäure und s-alpha-piperazincarbonsäureamid
IL132836A0 (en) 1997-05-12 2001-03-19 Ortho Mcneil Pharm Inc Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia
GB9821179D0 (en) * 1998-09-30 1998-11-25 Merck Sharp & Dohme Therapeutic use
JP2008124531A (ja) 2006-11-08 2008-05-29 Nec Electronics Corp 半導体装置およびオーディオプロセッサチップ
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1248531A (en) * 1984-04-17 1989-01-10 Jeffrey C. Watkins 4-substituted piperazine-2-carboxylic acids

Also Published As

Publication number Publication date
GR880100084A (el) 1988-12-16
PT86776B (pt) 1992-05-29
GR1002471B (el) 1996-11-15
HU199858B (en) 1990-03-28
SE8800541D0 (sv) 1988-02-17
FI880744A0 (fi) 1988-02-17
CY1739A (en) 1995-10-20
ES2021904A6 (es) 1991-11-16
FI86733C (fi) 1992-10-12
FI880744L (fi) 1988-08-19
PT86776A (pt) 1988-03-01
MY103206A (en) 1993-05-29
IE880413L (en) 1988-08-18
IL85436A (enrdf_load_stackoverflow) 1992-12-01
JPH0723387B2 (ja) 1995-03-15
AT391320B (de) 1990-09-25
GB8803438D0 (en) 1988-03-16
GB2201676B (en) 1991-01-02
CA1327799C (en) 1994-03-15
FR2610932B1 (fr) 1990-11-16
HU211269A9 (en) 1995-11-28
DE3804936C2 (de) 1997-02-13
ZA881146B (en) 1989-10-25
AU613009B2 (en) 1991-07-25
PH25512A (en) 1991-07-24
KR880009944A (ko) 1988-10-06
NZ223529A (en) 1991-02-26
IT1219447B (it) 1990-05-18
FI86733B (fi) 1992-06-30
JPS63203691A (ja) 1988-08-23
DK168441B1 (da) 1994-03-28
BE1002427A3 (fr) 1991-02-05
SE467256B (sv) 1992-06-22
IL85436A0 (en) 1988-07-31
KR960015190B1 (ko) 1996-11-01
LU87129A1 (fr) 1988-09-20
CH675125A5 (enrdf_load_stackoverflow) 1990-08-31
AU1175888A (en) 1988-08-25
DK79688D0 (da) 1988-02-16
ATA36788A (de) 1990-03-15
DE3804936A1 (de) 1988-09-01
NL8800412A (nl) 1988-09-16
GB8703749D0 (en) 1987-03-25
IT8847631A0 (it) 1988-02-12
ES2011319A6 (es) 1990-01-01
FR2610932A1 (fr) 1988-08-19
HUT49361A (en) 1989-09-28
GB2201676A (en) 1988-09-07
DK79688A (da) 1988-08-19
HK142093A (en) 1994-01-07

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