ES2021904A6 - Procedimiento para preparar una composicion farmaceutica a base de un acido piperacinacarboxilico. - Google Patents

Procedimiento para preparar una composicion farmaceutica a base de un acido piperacinacarboxilico.

Info

Publication number
ES2021904A6
ES2021904A6 ES8903482A ES8903482A ES2021904A6 ES 2021904 A6 ES2021904 A6 ES 2021904A6 ES 8903482 A ES8903482 A ES 8903482A ES 8903482 A ES8903482 A ES 8903482A ES 2021904 A6 ES2021904 A6 ES 2021904A6
Authority
ES
Spain
Prior art keywords
piperazinecarboxylic acid
preparation
pharmaceutical compositions
compositions containing
disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8903482A
Other languages
English (en)
Inventor
Bernhard Aebischer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES2021904A6 publication Critical patent/ES2021904A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UNA COMPOSICION FARMACEUTICA A BASE DE ACIDO PIPERACINACARBOXILICO. COMPRENDE MEZCLAR UN ACIDO [R-(E)]-4-(3-FOSFONO-2-PROPENIL)-2-PIPERACINACARBOXILICO DE FORMULA (I) O UN HIDRATO O UNA SAL DEL MISMO, CON UN VEHICULO O DILUYENTE FARMACEUTICAMENTE ACEPTABLE, TAL COMO PARA PRODUCIR UNA FORMA DE UNIDAD DE DOSIFICACION QUE CONTIENE APROXIMADAMENTE DE 0,25 A 0,400 MG DEL COMPUESTO DE FORMULA (I). LA COMPOSICION ASI OBTENIDA POSEE ACTIVIDAD SOBRE EL SISTEMA NERVIOSO CENTRAL.
ES8903482A 1987-02-18 1989-10-16 Procedimiento para preparar una composicion farmaceutica a base de un acido piperacinacarboxilico. Expired - Lifetime ES2021904A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878703749A GB8703749D0 (en) 1987-02-18 1987-02-18 Piperazinecarboxylic acid

Publications (1)

Publication Number Publication Date
ES2021904A6 true ES2021904A6 (es) 1991-11-16

Family

ID=10612501

Family Applications (2)

Application Number Title Priority Date Filing Date
ES888800466A Expired - Lifetime ES2011319A6 (es) 1987-02-18 1988-02-18 Procedimiento para preparar acidos piperacinacarboxilicos.
ES8903482A Expired - Lifetime ES2021904A6 (es) 1987-02-18 1989-10-16 Procedimiento para preparar una composicion farmaceutica a base de un acido piperacinacarboxilico.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES888800466A Expired - Lifetime ES2011319A6 (es) 1987-02-18 1988-02-18 Procedimiento para preparar acidos piperacinacarboxilicos.

Country Status (28)

Country Link
JP (1) JPH0723387B2 (es)
KR (1) KR960015190B1 (es)
AT (1) AT391320B (es)
AU (1) AU613009B2 (es)
BE (1) BE1002427A3 (es)
CA (1) CA1327799C (es)
CH (1) CH675125A5 (es)
CY (1) CY1739A (es)
DE (1) DE3804936C2 (es)
DK (1) DK168441B1 (es)
ES (2) ES2011319A6 (es)
FI (1) FI86733C (es)
FR (1) FR2610932B1 (es)
GB (2) GB8703749D0 (es)
GR (1) GR1002471B (es)
HK (1) HK142093A (es)
HU (2) HU199858B (es)
IE (1) IE59098B1 (es)
IL (1) IL85436A0 (es)
IT (1) IT1219447B (es)
LU (1) LU87129A1 (es)
MY (1) MY103206A (es)
NL (1) NL8800412A (es)
NZ (1) NZ223529A (es)
PH (1) PH25512A (es)
PT (1) PT86776B (es)
SE (1) SE467256B (es)
ZA (1) ZA881146B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU202111B (en) * 1988-03-11 1991-02-28 Sandoz Ag Process for producing pharmaceutical compositions containing (r)-(e)-4--(3-phosphono-2-propenyl)-2-piperazine-carboxylic acid as active component
US5086072A (en) * 1990-06-18 1992-02-04 The United States Of America As Represented By The Department Of Health And Human Services Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex
EP0488959A3 (en) * 1990-11-28 1992-08-05 Sandoz Ltd. New uses of competitive nmda receptor antagonists
US5260286A (en) * 1992-10-16 1993-11-09 Japan Tobacco, Inc. 2-piperidinecarboxylic acid derivatives useful as NMDA receptor antagonists
EP0826032A1 (de) * 1995-05-08 1998-03-04 Lonza Ag Biotechnologisches verfahren zur herstellung von r-alpha-piperazincarbonsäure und s-alpha-piperazincarbonsäureamid
HUP0100048A3 (en) 1997-05-12 2002-12-28 Ortho Mcneil Pharm Inc Arylsubstituted piperazine-derivatives, useful in the treatement of benign prostatic hyperlasia use of them for producing pharmaceutical compositions and pharmaceutical compositions containing them
GB9821179D0 (en) * 1998-09-30 1998-11-25 Merck Sharp & Dohme Therapeutic use
JP2008124531A (ja) 2006-11-08 2008-05-29 Nec Electronics Corp 半導体装置およびオーディオプロセッサチップ
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1248531A (en) * 1984-04-17 1989-01-10 Jeffrey C. Watkins 4-substituted piperazine-2-carboxylic acids

Also Published As

Publication number Publication date
IT8847631A0 (it) 1988-02-12
JPH0723387B2 (ja) 1995-03-15
ZA881146B (en) 1989-10-25
GB2201676B (en) 1991-01-02
KR880009944A (ko) 1988-10-06
DK168441B1 (da) 1994-03-28
FI86733B (fi) 1992-06-30
AT391320B (de) 1990-09-25
JPS63203691A (ja) 1988-08-23
GB8703749D0 (en) 1987-03-25
LU87129A1 (fr) 1988-09-20
GR1002471B (el) 1996-11-15
PH25512A (en) 1991-07-24
DE3804936C2 (de) 1997-02-13
CA1327799C (en) 1994-03-15
DK79688A (da) 1988-08-19
FR2610932A1 (fr) 1988-08-19
ES2011319A6 (es) 1990-01-01
IL85436A (es) 1992-12-01
DE3804936A1 (de) 1988-09-01
SE8800541D0 (sv) 1988-02-17
FI880744A (fi) 1988-08-19
BE1002427A3 (fr) 1991-02-05
GB8803438D0 (en) 1988-03-16
HU199858B (en) 1990-03-28
DK79688D0 (da) 1988-02-16
SE467256B (sv) 1992-06-22
HU211269A9 (en) 1995-11-28
SE8800541A (es) 1988-08-19
AU1175888A (en) 1988-08-25
CY1739A (en) 1995-10-20
NZ223529A (en) 1991-02-26
IL85436A0 (en) 1988-07-31
IT1219447B (it) 1990-05-18
NL8800412A (nl) 1988-09-16
CH675125A5 (es) 1990-08-31
FI86733C (fi) 1992-10-12
PT86776A (pt) 1988-03-01
HK142093A (en) 1994-01-07
IE59098B1 (en) 1994-01-12
ATA36788A (de) 1990-03-15
FI880744A0 (fi) 1988-02-17
MY103206A (en) 1993-05-29
PT86776B (pt) 1992-05-29
GR880100084A (el) 1988-12-16
KR960015190B1 (ko) 1996-11-01
IE880413L (en) 1988-08-18
AU613009B2 (en) 1991-07-25
FR2610932B1 (fr) 1990-11-16
GB2201676A (en) 1988-09-07
HUT49361A (en) 1989-09-28

Similar Documents

Publication Publication Date Title
EP0592490A4 (en) Amino acid derivative anticonvulsant
GB8817585D0 (en) Improvements in/relating to apparatus for use in treatment of spinal disorders
PL298195A1 (en) Sulfonamido- and sulfonabidocabonyl-pyridine-2-carboxylic acid amides and their pyridine-n-oxides, method of obtaining them and their application as therapeutic agents as well therapeutic agents containing them and method of obtaining such therapeutic
GB2207055B (en) Apparatus for use in the treatment of spinal disorders
IL83363A (en) Use of indol-3-yl-carboxylic acid endo-8-methyl-8-aza- bicyclo (3,2,1) oct-3-yl ester for the preparation of psycho-active pharmaceutical compositions suitable for the treatment of stress- related psychiatric disorders or for increasing vigilance
IL76454A0 (en) Diarylacetylenes,their preparation and pharmaceutical compositions containing them
IL98810A0 (en) Pharmaceutical compositions containing flupirtine for combating muscular tension disorders and their preparation
AU2399892A (en) Treatment of anxiety disorders by nerve stimulation
ES2011319A6 (es) Procedimiento para preparar acidos piperacinacarboxilicos.
ES8705852A1 (es) Un procedimiento para la preparacion de nuevas benzamidas sustituidas
GB9418912D0 (en) Pharmaceutically active compounds
AU642428B2 (en) Method of treatment of CNS disorders and /or pain using gamma aminobutyric acid autoreceptor antagonists
EP0383171A3 (en) 2,3,23-trihydroxy-urs-12-ene derivatives for treating cognitive disorders
EP0273310A3 (en) 5-aryl-3h-1,2,4-triazol-3-ones and their use as anticonvulsants
MY105555A (en) Heterocyclicguanidines as 5ht 3 antagonists.
GB8808598D0 (en) Pharmaceutical compositions for treatment of prophylaxis of skin disorders
ZA883144B (en) Novel substituted silyl alkylene amines
MY103584A (en) 8(alpha)-acylaminoergoline, its preparation and pharmaceutical compositions containing it
ZA884835B (en) Treatment of cerebral disorders
HUT46921A (en) Process for producing 3-phenyl-7h-thiazolo /3,2-b//1,2,4/ triazin-7-ones, certain intermediaries thereof and pharmaceutics comprising such active ingredient
IL124730A0 (en) Compositions comprising bismuth and one or more antimicrobials for the prevention and treatment of gastrointestinal disorders
IL124792A0 (en) Compositions containing bismuth and one or more antimicrobials for the prevention and treatment of gastrointestinal disorders
IL124729A (en) Use of bismuth for the manufacture of compositions for the treatment and prevention of gastrointestinal disorders
ES8502128A1 (es) Procedimiento para la preparacion de derivados de 6 -metilprednisolona
Morizono et al. Experience in the treatment of shoulder-hand syndrome

Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20041004