IE880413L - Producing a piperazine - Google Patents

Producing a piperazine

Info

Publication number
IE880413L
IE880413L IE880413A IE41388A IE880413L IE 880413 L IE880413 L IE 880413L IE 880413 A IE880413 A IE 880413A IE 41388 A IE41388 A IE 41388A IE 880413 L IE880413 L IE 880413L
Authority
IE
Ireland
Prior art keywords
piperazinecarboxylic acid
piperazine
producing
disorders
ca1327799c
Prior art date
Application number
IE880413A
Other versions
IE59098B1 (en
Inventor
Bernhard Aebischer
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of IE880413L publication Critical patent/IE880413L/en
Publication of IE59098B1 publication Critical patent/IE59098B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PIPERAZINECARBOXYLIC ACID, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT Piperazinecarboxylic acid of formula I, <IMG> I is useful in the treatment of disorders associated with LH secretion, increased muscle tone, conditions associated with cerebral ischaemia, anxiety, depression, CNS degenerative disorders, tinnitus, epilepsy or in relieving pain. [CA1327799C]
IE41388A 1987-02-18 1988-02-16 Piperazinecarboxylic acid, its preparation and pharmaceutical compositions containing it IE59098B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878703749A GB8703749D0 (en) 1987-02-18 1987-02-18 Piperazinecarboxylic acid

Publications (2)

Publication Number Publication Date
IE880413L true IE880413L (en) 1988-08-18
IE59098B1 IE59098B1 (en) 1994-01-12

Family

ID=10612501

Family Applications (1)

Application Number Title Priority Date Filing Date
IE41388A IE59098B1 (en) 1987-02-18 1988-02-16 Piperazinecarboxylic acid, its preparation and pharmaceutical compositions containing it

Country Status (28)

Country Link
JP (1) JPH0723387B2 (en)
KR (1) KR960015190B1 (en)
AT (1) AT391320B (en)
AU (1) AU613009B2 (en)
BE (1) BE1002427A3 (en)
CA (1) CA1327799C (en)
CH (1) CH675125A5 (en)
CY (1) CY1739A (en)
DE (1) DE3804936C2 (en)
DK (1) DK168441B1 (en)
ES (2) ES2011319A6 (en)
FI (1) FI86733C (en)
FR (1) FR2610932B1 (en)
GB (2) GB8703749D0 (en)
GR (1) GR1002471B (en)
HK (1) HK142093A (en)
HU (2) HU199858B (en)
IE (1) IE59098B1 (en)
IL (1) IL85436A0 (en)
IT (1) IT1219447B (en)
LU (1) LU87129A1 (en)
MY (1) MY103206A (en)
NL (1) NL8800412A (en)
NZ (1) NZ223529A (en)
PH (1) PH25512A (en)
PT (1) PT86776B (en)
SE (1) SE467256B (en)
ZA (1) ZA881146B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU202111B (en) * 1988-03-11 1991-02-28 Sandoz Ag Process for producing pharmaceutical compositions containing (r)-(e)-4--(3-phosphono-2-propenyl)-2-piperazine-carboxylic acid as active component
US5086072A (en) * 1990-06-18 1992-02-04 The United States Of America As Represented By The Department Of Health And Human Services Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex
EP0488959A3 (en) * 1990-11-28 1992-08-05 Sandoz Ltd. New uses of competitive nmda receptor antagonists
US5260286A (en) * 1992-10-16 1993-11-09 Japan Tobacco, Inc. 2-piperidinecarboxylic acid derivatives useful as NMDA receptor antagonists
EP0826032A1 (en) * 1995-05-08 1998-03-04 Lonza Ag BIOTECHNICAL PRODUCTION PROCESS OF PIPERAZINE R-$g(a)-CARBOXYLIC ACIDS AND PIPERAZINE S-$g(a)-CARBOXYLIC ACID AMIDE
HUP0100048A3 (en) 1997-05-12 2002-12-28 Ortho Mcneil Pharm Inc Arylsubstituted piperazine-derivatives, useful in the treatement of benign prostatic hyperlasia use of them for producing pharmaceutical compositions and pharmaceutical compositions containing them
GB9821179D0 (en) * 1998-09-30 1998-11-25 Merck Sharp & Dohme Therapeutic use
JP2008124531A (en) 2006-11-08 2008-05-29 Nec Electronics Corp Semiconductor device and audio processor chip
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1248531A (en) * 1984-04-17 1989-01-10 Jeffrey C. Watkins 4-substituted piperazine-2-carboxylic acids

Also Published As

Publication number Publication date
IT8847631A0 (en) 1988-02-12
JPH0723387B2 (en) 1995-03-15
ZA881146B (en) 1989-10-25
GB2201676B (en) 1991-01-02
KR880009944A (en) 1988-10-06
DK168441B1 (en) 1994-03-28
FI86733B (en) 1992-06-30
AT391320B (en) 1990-09-25
JPS63203691A (en) 1988-08-23
GB8703749D0 (en) 1987-03-25
LU87129A1 (en) 1988-09-20
GR1002471B (en) 1996-11-15
PH25512A (en) 1991-07-24
DE3804936C2 (en) 1997-02-13
CA1327799C (en) 1994-03-15
DK79688A (en) 1988-08-19
FR2610932A1 (en) 1988-08-19
ES2011319A6 (en) 1990-01-01
IL85436A (en) 1992-12-01
DE3804936A1 (en) 1988-09-01
SE8800541D0 (en) 1988-02-17
ES2021904A6 (en) 1991-11-16
FI880744A (en) 1988-08-19
BE1002427A3 (en) 1991-02-05
GB8803438D0 (en) 1988-03-16
HU199858B (en) 1990-03-28
DK79688D0 (en) 1988-02-16
SE467256B (en) 1992-06-22
HU211269A9 (en) 1995-11-28
SE8800541A (en) 1988-08-19
AU1175888A (en) 1988-08-25
CY1739A (en) 1995-10-20
NZ223529A (en) 1991-02-26
IL85436A0 (en) 1988-07-31
IT1219447B (en) 1990-05-18
NL8800412A (en) 1988-09-16
CH675125A5 (en) 1990-08-31
FI86733C (en) 1992-10-12
PT86776A (en) 1988-03-01
HK142093A (en) 1994-01-07
IE59098B1 (en) 1994-01-12
ATA36788A (en) 1990-03-15
FI880744A0 (en) 1988-02-17
MY103206A (en) 1993-05-29
PT86776B (en) 1992-05-29
GR880100084A (en) 1988-12-16
KR960015190B1 (en) 1996-11-01
AU613009B2 (en) 1991-07-25
FR2610932B1 (en) 1990-11-16
GB2201676A (en) 1988-09-07
HUT49361A (en) 1989-09-28

Similar Documents

Publication Publication Date Title
IL83363A (en) Use of indol-3-yl-carboxylic acid endo-8-methyl-8-aza- bicyclo (3,2,1) oct-3-yl ester for the preparation of psycho-active pharmaceutical compositions suitable for the treatment of stress- related psychiatric disorders or for increasing vigilance
GB2208476B (en) Improvements in or relating to apparatus for use in the treatment of spinal disorders
HUT69685A (en) Sulphonamido and sulphonamido-carbonyl-pyridine-2-carboxylic acid amides, their n-oxides, method for producing them and pharmaceutical preparatives containing them
CA2395193A1 (en) Pyrrolidine derivatives as cyclic amp-specific phosphodiesterase inhibitors
MXPA01007662A (en) Highly purified ethyl epa and other epa derivatives for psychiatric and neurological disorders.
AU2399892A (en) Treatment of anxiety disorders by nerve stimulation
HUP0301167A3 (en) Sulfonyl-pyrrolidine derivatives useful for the treatment of neurological disorders, process for their preparation, pharmaceutical compositions containing them and their use
IE880413L (en) Producing a piperazine
BG105012A (en) N-linked sulphonamides of n-heterocyclic carboxylic acids or carboxylic isosteres
AU642428B2 (en) Method of treatment of CNS disorders and /or pain using gamma aminobutyric acid autoreceptor antagonists
BE902040A (en) SUBSTITUTED ALPHA-AMINO ACIDS, THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
BG104485A (en) 1&#39;[4-[1-(4-fluorophenyl)-1h-indole-3-yl]-1-butyl]- spiro[isobenzofuran-1-(3h),4&#39;-piperidine] hydrohalogenides
EP0383171A3 (en) 2,3,23-trihydroxy-urs-12-ene derivatives for treating cognitive disorders
AU2101288A (en) Taliscanin and other aristolactams for treating neurological disorders, parkinson&#39;s disease, alzheimer disease and impotence
WO2002005801A3 (en) Compositions containing diacyltartaric salts of (e)-metanicotine
UA42731C2 (en) Arylalkyl-thiadiazinones, process for preparation thereof, pharmaceutical composition, process for preparation thereof and treatment method
AU1546101A (en) Pharmaceutical compositions comprising acetylcholinesterase antisense deoxynucleotides for the treatment of muscular and neuromuscular disorders
CA2261259A1 (en) Alpha-amino acid amides, preparation thereof and the therapeutical use thereof
BG105014A (en) Ureas and carbamates of n-heterocyclic carboxylic acids and carboxylic acid isosteres
CA2395196A1 (en) Cyclic amp-specific phosphodiesterase inhibitors
HUT49284A (en) Process for production of medical compositions applicable &#34;in loco&#34; against androgene hairlessness
MY105555A (en) Heterocyclicguanidines as 5ht 3 antagonists.
AP2000001793A0 (en) Novel polymorph forms.
ES2009689A6 (en) Derivatives of 3-piperidine carbaldehyde oxime and their use as medicaments
GB8808598D0 (en) Pharmaceutical compositions for treatment of prophylaxis of skin disorders

Legal Events

Date Code Title Description
MM4A Patent lapsed