BE1002427A3 - Nouvel acide piperazinecarboxylique, sa preparation et son utilisation comme medicament. - Google Patents
Nouvel acide piperazinecarboxylique, sa preparation et son utilisation comme medicament. Download PDFInfo
- Publication number
- BE1002427A3 BE1002427A3 BE8800177A BE8800177A BE1002427A3 BE 1002427 A3 BE1002427 A3 BE 1002427A3 BE 8800177 A BE8800177 A BE 8800177A BE 8800177 A BE8800177 A BE 8800177A BE 1002427 A3 BE1002427 A3 BE 1002427A3
- Authority
- BE
- Belgium
- Prior art keywords
- medicine
- novel
- preparation
- piperazinecarboxylic acid
- piperazinecarboxylic
- Prior art date
Links
- RFIOZSIHFNEKFF-UHFFFAOYSA-N piperazine-1-carboxylic acid Chemical compound OC(=O)N1CCNCC1 RFIOZSIHFNEKFF-UHFFFAOYSA-N 0.000 title 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention a pour objet l'acide [R(E)]-4-(3-phosphono-2-propényl)-pipérazine-2-carboxylique de formule I et ses sels. Ce composé exerce une activité sur le système nerveux central et peut être utilisé comme médicament.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878703749A GB8703749D0 (en) | 1987-02-18 | 1987-02-18 | Piperazinecarboxylic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
BE1002427A3 true BE1002427A3 (fr) | 1991-02-05 |
Family
ID=10612501
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE8800177A BE1002427A3 (fr) | 1987-02-18 | 1988-02-12 | Nouvel acide piperazinecarboxylique, sa preparation et son utilisation comme medicament. |
Country Status (28)
Country | Link |
---|---|
JP (1) | JPH0723387B2 (fr) |
KR (1) | KR960015190B1 (fr) |
AT (1) | AT391320B (fr) |
AU (1) | AU613009B2 (fr) |
BE (1) | BE1002427A3 (fr) |
CA (1) | CA1327799C (fr) |
CH (1) | CH675125A5 (fr) |
CY (1) | CY1739A (fr) |
DE (1) | DE3804936C2 (fr) |
DK (1) | DK168441B1 (fr) |
ES (2) | ES2011319A6 (fr) |
FI (1) | FI86733C (fr) |
FR (1) | FR2610932B1 (fr) |
GB (2) | GB8703749D0 (fr) |
GR (1) | GR1002471B (fr) |
HK (1) | HK142093A (fr) |
HU (2) | HU199858B (fr) |
IE (1) | IE59098B1 (fr) |
IL (1) | IL85436A0 (fr) |
IT (1) | IT1219447B (fr) |
LU (1) | LU87129A1 (fr) |
MY (1) | MY103206A (fr) |
NL (1) | NL8800412A (fr) |
NZ (1) | NZ223529A (fr) |
PH (1) | PH25512A (fr) |
PT (1) | PT86776B (fr) |
SE (1) | SE467256B (fr) |
ZA (1) | ZA881146B (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU202111B (en) * | 1988-03-11 | 1991-02-28 | Sandoz Ag | Process for producing pharmaceutical compositions containing (r)-(e)-4--(3-phosphono-2-propenyl)-2-piperazine-carboxylic acid as active component |
US5086072A (en) * | 1990-06-18 | 1992-02-04 | The United States Of America As Represented By The Department Of Health And Human Services | Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex |
EP0488959A3 (en) * | 1990-11-28 | 1992-08-05 | Sandoz Ltd. | New uses of competitive nmda receptor antagonists |
US5260286A (en) * | 1992-10-16 | 1993-11-09 | Japan Tobacco, Inc. | 2-piperidinecarboxylic acid derivatives useful as NMDA receptor antagonists |
AU5693996A (en) * | 1995-05-08 | 1996-11-29 | Lonza A.G. | Biotechnical production process of piperazine r-alpha-carbox ylic acids and piperazine s-alpha-carboxylic acid amide |
EP0984777B1 (fr) | 1997-05-12 | 2003-09-17 | Ortho-Mcneil Pharmaceutical, Inc. | Piperazines a substitution aryle utiles dans le traitement de l'adenome prostatique |
GB9821179D0 (en) * | 1998-09-30 | 1998-11-25 | Merck Sharp & Dohme | Therapeutic use |
JP2008124531A (ja) | 2006-11-08 | 2008-05-29 | Nec Electronics Corp | 半導体装置およびオーディオプロセッサチップ |
EP3427729A1 (fr) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probénécide destiné à être utilisé dans le traitement de maladies, troubles ou états épileptiques |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0159889A2 (fr) * | 1984-04-17 | 1985-10-30 | Btg International Limited | Acides pipérazine-2-carboxyliques, substitués en position 4, procédé et compositions pharmaceutiques |
-
1987
- 1987-02-18 GB GB878703749A patent/GB8703749D0/en active Pending
-
1988
- 1988-02-11 LU LU87129A patent/LU87129A1/fr unknown
- 1988-02-12 BE BE8800177A patent/BE1002427A3/fr active
- 1988-02-12 FR FR888801782A patent/FR2610932B1/fr not_active Expired - Lifetime
- 1988-02-12 IT IT47631/88A patent/IT1219447B/it active
- 1988-02-15 GB GB8803438A patent/GB2201676B/en not_active Expired - Lifetime
- 1988-02-15 MY MYPI88000155A patent/MY103206A/en unknown
- 1988-02-16 CH CH549/88A patent/CH675125A5/de not_active IP Right Cessation
- 1988-02-16 GR GR880100084A patent/GR1002471B/el not_active IP Right Cessation
- 1988-02-16 PH PH36514A patent/PH25512A/en unknown
- 1988-02-16 HU HU88746A patent/HU199858B/hu not_active IP Right Cessation
- 1988-02-16 CA CA000559170A patent/CA1327799C/fr not_active Expired - Fee Related
- 1988-02-16 IL IL85436A patent/IL85436A0/xx not_active IP Right Cessation
- 1988-02-16 DK DK079688A patent/DK168441B1/da not_active IP Right Cessation
- 1988-02-16 AU AU11758/88A patent/AU613009B2/en not_active Ceased
- 1988-02-16 IE IE41388A patent/IE59098B1/en not_active IP Right Cessation
- 1988-02-16 NZ NZ223529A patent/NZ223529A/xx unknown
- 1988-02-17 JP JP63036458A patent/JPH0723387B2/ja not_active Expired - Lifetime
- 1988-02-17 PT PT86776A patent/PT86776B/pt not_active IP Right Cessation
- 1988-02-17 KR KR1019880001680A patent/KR960015190B1/ko not_active IP Right Cessation
- 1988-02-17 DE DE3804936A patent/DE3804936C2/de not_active Expired - Fee Related
- 1988-02-17 SE SE8800541A patent/SE467256B/sv not_active IP Right Cessation
- 1988-02-17 AT AT0036788A patent/AT391320B/de not_active IP Right Cessation
- 1988-02-17 FI FI880744A patent/FI86733C/fi not_active IP Right Cessation
- 1988-02-18 NL NL8800412A patent/NL8800412A/nl not_active Application Discontinuation
- 1988-02-18 ZA ZA881146A patent/ZA881146B/xx unknown
- 1988-02-18 ES ES888800466A patent/ES2011319A6/es not_active Expired - Lifetime
-
1989
- 1989-10-16 ES ES8903482A patent/ES2021904A6/es not_active Expired - Lifetime
-
1993
- 1993-12-30 HK HK1420/93A patent/HK142093A/xx not_active IP Right Cessation
-
1995
- 1995-06-09 HU HU95P/P00176P patent/HU211269A9/hu unknown
- 1995-10-20 CY CY173995A patent/CY1739A/xx unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0159889A2 (fr) * | 1984-04-17 | 1985-10-30 | Btg International Limited | Acides pipérazine-2-carboxyliques, substitués en position 4, procédé et compositions pharmaceutiques |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8705387A1 (es) | Un procedimiento para preparar derivados de n-aril-n-(4-piperidinil)-alcoxialquilamida | |
TNSN97032A1 (fr) | Nouvelles oxazolidinones substituees, procedes pour les preparer, et leur utilisation en tant que medicaments. | |
LU90710I2 (fr) | Galanthamine ou ses sels d'addition acides | |
FI901421A0 (fi) | N-(3-hydroxi-4-piperidinyl) (dihydrobenzofuran, dihydro-2h-benzopyran- eller dihydrobenzodioxin) karboxiamidderivat. | |
FI872864A (fi) | Menetelmä farmaseuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi | |
BE1002427A3 (fr) | Nouvel acide piperazinecarboxylique, sa preparation et son utilisation comme medicament. | |
ATE79257T1 (de) | Verwendung von tetrahydrobenz(c,d>indol-6carboxamiden zur herstellung von arzneimitteln zur behandlung von angstzustaenden. | |
EP0330052A3 (fr) | Utilisation de benzimidazoles pour la préparation de médicaments à activité anti-ischémique cardiaque et combinaisons avec des bêta-bloquants ou des agents bradycardisants | |
TNSN90021A1 (fr) | Procede de preparation de tetrahydroimidazo (1,4) benzodiazepin -2- thiones antivirales | |
ATE26273T1 (de) | 3-indolcarboxamid-verbindungen. | |
ES8404850A1 (es) | Procedimiento para la obtencion de 2-nitro-1,1-etendiaminas | |
ATE41772T1 (de) | Polymethoxybenzyl-piperazin-derivate, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen. | |
FR2450820A1 (fr) | Nouveaux derives d'acides 1- (o-mercaptoacyl) -4,5-dihydropyrazole-5-carboxyliques, utiles notamment comme agents hypotenseurs, et leur procede de preparation | |
KR860000269A (ko) | 칼슘길항성의 1-[비스-(4-플루오로페닐)-메틸-4-(3-페닐-2-프로페닐)-헥사하이드로-1h-1, 4-디아제핀의 제조방법및 이것을 함유한 약학적조성물 | |
DK167384D0 (da) | Penemer,farmaceutiske praeparater indeholdende disse,samt fremgangsmaader til fremstilling deraf | |
KR890006621A (ko) | 항불안제 | |
ATE26841T1 (de) | Verbindungen zur behandlung von erhoehtem blutdruck. | |
DE3778642D1 (de) | Therapeutikum zur behandlung von magengeschwueren. | |
DE3872425T2 (de) | Substituierte tetrahydroisochinolin-verbindungen, ihre herstellung und diese enthaltende pharmazeutische mittel. | |
SE8701592D0 (sv) | A pharmaceutical composition comprising an organic zinc complex and a process for preparing the active substance | |
FR2435465A1 (fr) | Aminoalcoylguanidines substituees, leur preparation et leur application a titre de medicaments | |
FR2374321A1 (fr) | Utilisation de quinoxalinedioxydes pour promouvoir la croissance et ameliorer le rendement alimentaire d'animaux | |
EP0250508A1 (fr) | Medicament pour le traitement des maladies du foie | |
BE905718A (fr) | Compositions pharmaceutiques contenant la 2-methyl-thiazolo[4,5-c]quinoleine et leur procede de preparation. | |
ES2004215A6 (es) | Procedimiento para preparar quinazolinas tetraciclicas |