BE1002427A3 - Nouvel acide piperazinecarboxylique, sa preparation et son utilisation comme medicament. - Google Patents

Nouvel acide piperazinecarboxylique, sa preparation et son utilisation comme medicament. Download PDF

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Publication number
BE1002427A3
BE1002427A3 BE8800177A BE8800177A BE1002427A3 BE 1002427 A3 BE1002427 A3 BE 1002427A3 BE 8800177 A BE8800177 A BE 8800177A BE 8800177 A BE8800177 A BE 8800177A BE 1002427 A3 BE1002427 A3 BE 1002427A3
Authority
BE
Belgium
Prior art keywords
medicine
novel
preparation
piperazinecarboxylic acid
piperazinecarboxylic
Prior art date
Application number
BE8800177A
Other languages
English (en)
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Application granted granted Critical
Publication of BE1002427A3 publication Critical patent/BE1002427A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention a pour objet l'acide [R(E)]-4-(3-phosphono-2-propényl)-pipérazine-2-carboxylique de formule I et ses sels. Ce composé exerce une activité sur le système nerveux central et peut être utilisé comme médicament.
BE8800177A 1987-02-18 1988-02-12 Nouvel acide piperazinecarboxylique, sa preparation et son utilisation comme medicament. BE1002427A3 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878703749A GB8703749D0 (en) 1987-02-18 1987-02-18 Piperazinecarboxylic acid

Publications (1)

Publication Number Publication Date
BE1002427A3 true BE1002427A3 (fr) 1991-02-05

Family

ID=10612501

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8800177A BE1002427A3 (fr) 1987-02-18 1988-02-12 Nouvel acide piperazinecarboxylique, sa preparation et son utilisation comme medicament.

Country Status (28)

Country Link
JP (1) JPH0723387B2 (fr)
KR (1) KR960015190B1 (fr)
AT (1) AT391320B (fr)
AU (1) AU613009B2 (fr)
BE (1) BE1002427A3 (fr)
CA (1) CA1327799C (fr)
CH (1) CH675125A5 (fr)
CY (1) CY1739A (fr)
DE (1) DE3804936C2 (fr)
DK (1) DK168441B1 (fr)
ES (2) ES2011319A6 (fr)
FI (1) FI86733C (fr)
FR (1) FR2610932B1 (fr)
GB (2) GB8703749D0 (fr)
GR (1) GR1002471B (fr)
HK (1) HK142093A (fr)
HU (2) HU199858B (fr)
IE (1) IE59098B1 (fr)
IL (1) IL85436A0 (fr)
IT (1) IT1219447B (fr)
LU (1) LU87129A1 (fr)
MY (1) MY103206A (fr)
NL (1) NL8800412A (fr)
NZ (1) NZ223529A (fr)
PH (1) PH25512A (fr)
PT (1) PT86776B (fr)
SE (1) SE467256B (fr)
ZA (1) ZA881146B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU202111B (en) * 1988-03-11 1991-02-28 Sandoz Ag Process for producing pharmaceutical compositions containing (r)-(e)-4--(3-phosphono-2-propenyl)-2-piperazine-carboxylic acid as active component
US5086072A (en) * 1990-06-18 1992-02-04 The United States Of America As Represented By The Department Of Health And Human Services Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex
EP0488959A3 (en) * 1990-11-28 1992-08-05 Sandoz Ltd. New uses of competitive nmda receptor antagonists
US5260286A (en) * 1992-10-16 1993-11-09 Japan Tobacco, Inc. 2-piperidinecarboxylic acid derivatives useful as NMDA receptor antagonists
JPH11508761A (ja) * 1995-05-08 1999-08-03 ロンザ アーゲー Ｒ−α−ピペラジンカルボン酸およびＳ−α−ピペラジンカルボキサミドを製造する生物工学的方法
US6071915A (en) 1997-05-12 2000-06-06 Ortho-Mcneil Pharmaceutical, Inc. Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia
GB9821179D0 (en) * 1998-09-30 1998-11-25 Merck Sharp & Dohme Therapeutic use
JP2008124531A (ja) 2006-11-08 2008-05-29 Nec Electronics Corp 半導体装置およびオーディオプロセッサチップ
EP3427729A1 (fr) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probénécide destiné à être utilisé dans le traitement de maladies, troubles ou états épileptiques

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0159889A2 (fr) * 1984-04-17 1985-10-30 Btg International Limited Acides pipérazine-2-carboxyliques, substitués en position 4, procédé et compositions pharmaceutiques

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0159889A2 (fr) * 1984-04-17 1985-10-30 Btg International Limited Acides pipérazine-2-carboxyliques, substitués en position 4, procédé et compositions pharmaceutiques

Also Published As

Publication number Publication date
IE59098B1 (en) 1994-01-12
SE8800541D0 (sv) 1988-02-17
FI86733B (fi) 1992-06-30
CH675125A5 (fr) 1990-08-31
CA1327799C (fr) 1994-03-15
PT86776B (pt) 1992-05-29
KR880009944A (ko) 1988-10-06
GB8803438D0 (en) 1988-03-16
NZ223529A (en) 1991-02-26
AU613009B2 (en) 1991-07-25
DE3804936C2 (de) 1997-02-13
IL85436A0 (en) 1988-07-31
MY103206A (en) 1993-05-29
JPH0723387B2 (ja) 1995-03-15
GB2201676A (en) 1988-09-07
GR880100084A (el) 1988-12-16
FR2610932A1 (fr) 1988-08-19
IT8847631A0 (it) 1988-02-12
SE467256B (sv) 1992-06-22
DE3804936A1 (de) 1988-09-01
DK168441B1 (da) 1994-03-28
FI880744A (fi) 1988-08-19
ES2011319A6 (es) 1990-01-01
CY1739A (en) 1995-10-20
ATA36788A (de) 1990-03-15
ZA881146B (en) 1989-10-25
HUT49361A (en) 1989-09-28
GB2201676B (en) 1991-01-02
HU199858B (en) 1990-03-28
FR2610932B1 (fr) 1990-11-16
AU1175888A (en) 1988-08-25
ES2021904A6 (es) 1991-11-16
LU87129A1 (fr) 1988-09-20
HK142093A (en) 1994-01-07
HU211269A9 (en) 1995-11-28
FI86733C (fi) 1992-10-12
GR1002471B (el) 1996-11-15
AT391320B (de) 1990-09-25
DK79688D0 (da) 1988-02-16
PH25512A (en) 1991-07-24
PT86776A (pt) 1988-03-01
DK79688A (da) 1988-08-19
IL85436A (fr) 1992-12-01
SE8800541A (fr) 1988-08-19
IT1219447B (it) 1990-05-18
KR960015190B1 (ko) 1996-11-01
NL8800412A (nl) 1988-09-16
IE880413L (en) 1988-08-18
GB8703749D0 (en) 1987-03-25
FI880744A0 (fi) 1988-02-17
JPS63203691A (ja) 1988-08-23

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