ES8404850A1 - Procedimiento para la obtencion de 2-nitro-1,1-etendiaminas - Google Patents

Procedimiento para la obtencion de 2-nitro-1,1-etendiaminas

Info

Publication number
ES8404850A1
ES8404850A1 ES525256A ES525256A ES8404850A1 ES 8404850 A1 ES8404850 A1 ES 8404850A1 ES 525256 A ES525256 A ES 525256A ES 525256 A ES525256 A ES 525256A ES 8404850 A1 ES8404850 A1 ES 8404850A1
Authority
ES
Spain
Prior art keywords
optionally substituted
ethene
diamines
medicines
nitro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES525256A
Other languages
English (en)
Other versions
ES525256A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES525256A0 publication Critical patent/ES525256A0/es
Publication of ES8404850A1 publication Critical patent/ES8404850A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Ink Jet (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Lubricants (AREA)
  • Color Printing (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 2-NITRO-1,1-ETENDIAMIN AS, DE FORMULA (I), EN LA QUE X ES METILENO, EVENTUALMENTE SUSTITUIDO, O UN ENLACE; Y R Y R PUEDEN SER VARIOS TIPOS DE RADICALES.CONSISTE EN LA REACCION DE SUSTITUCION DE COMPUESTOS DE FORMULA (II) CON AMINAS, DE FORMULA R-NH2, O DE COMPUESTOS DE FORMULA (III), CON AMINAS DE FORMULA R-X-NH2, EN LAS QUE Y ES -5-ALQUILO O -50-ALQUILO, Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE EFECTUA EN UN DISOLVENTE ORGANICO INERTE, A UNA TEMPERATURA ENTRE 0JC Y 180JC.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICASPARA REDUCIR LA PRESION SANGUINEA.
ES525256A 1982-09-01 1983-08-31 Procedimiento para la obtencion de 2-nitro-1,1-etendiaminas Expired ES8404850A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823232462 DE3232462A1 (de) 1982-09-01 1982-09-01 2-nitro-1,1-ethendiamine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
ES525256A0 ES525256A0 (es) 1984-05-16
ES8404850A1 true ES8404850A1 (es) 1984-05-16

Family

ID=6172205

Family Applications (1)

Application Number Title Priority Date Filing Date
ES525256A Expired ES8404850A1 (es) 1982-09-01 1983-08-31 Procedimiento para la obtencion de 2-nitro-1,1-etendiaminas

Country Status (14)

Country Link
US (1) US4567188A (es)
EP (1) EP0104423B1 (es)
JP (1) JPS5965047A (es)
KR (1) KR840006324A (es)
AT (1) ATE19870T1 (es)
AU (1) AU1857083A (es)
DE (2) DE3232462A1 (es)
DK (1) DK397383A (es)
ES (1) ES8404850A1 (es)
FI (1) FI833075A (es)
GR (1) GR79627B (es)
IL (1) IL69598A (es)
PT (1) PT77231B (es)
ZA (1) ZA836450B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2096518A1 (es) * 1994-03-28 1997-03-01 Almirall Lab Nuevas anilinas.

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3856183T2 (de) * 1987-08-01 1998-11-05 Takeda Chemical Industries Ltd Zwischenprodukte, ihre Herstellung und Verwendung zur Herstellung alpha-ungesättigter Amine
US4918086A (en) * 1987-08-07 1990-04-17 Ciba-Geigy Corporation 1-nitro-2,2-diaminoethylene derivatives
JP2779403B2 (ja) * 1988-11-29 1998-07-23 日本バイエルアグロケム株式会社 殺虫性ニトロ化合物
DK0383091T3 (da) * 1989-02-13 1994-02-07 Bayer Agrochem Kk Insecticidt virksomme nitroforbindelser
US5204359A (en) * 1989-02-13 1993-04-20 Nihon Bayer Agrochem K.K. Insecticidally active nitro compounds
IL99161A (en) * 1990-08-17 1996-11-14 Takeda Chemical Industries Ltd History of guanidine A process for their preparation and preparations from pesticides that contain them
EP0501251A3 (en) * 1991-02-27 1993-03-10 Bayer Ag The enantiomer (+)-n-(2-ethoxyphenyl)-n',n'-(1,2,2-trimethylpropyl)-2-nitroethen-1,1-diamine, method for its preparation and its use
JPH0540417U (ja) * 1991-11-01 1993-06-01 積水化学工業株式会社 ユニツトルームの壁パネル接続構造
EP0561237A3 (en) * 1992-03-18 1993-11-24 Bayer Ag Enantiomer, (-)-n-(2-ethoxyphenyl)-n'-(1,2,2-trimethylpropyl)-2-nitromethene-1,1-diamine, process for its preparation and its use
US5328830A (en) * 1992-09-08 1994-07-12 Miles Inc. Potassium channel modulators
EP0622673B1 (en) * 1993-04-24 1998-02-04 Kodak Limited Photographic colour couplers and photographic materials containing them
CA2331299A1 (en) * 1998-05-11 1999-11-18 Novo Nordisk A/S Substituted guanidines and diaminonitroethenes, their preparation and use
US6147098A (en) * 1998-05-11 2000-11-14 Novo Nordisk A/S Substituted guanidines and diaminonitroethenes, their preparation and use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1421792A (en) * 1973-05-17 1976-01-21 Smith Kline French Lab Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them
IL49528A (en) * 1975-05-21 1980-11-30 Smith Kline French Lab Imidazolyl(or thiazolyl)methylthio(or butyl)guanidine or thiourea derivatives,their preparation and pharmaceutical compositions comprising them
GB1564502A (en) * 1975-07-31 1980-04-10 Smith Kline French Lab Guanidines thioureas and 1,1-diamino-2-nitroethylene derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2096518A1 (es) * 1994-03-28 1997-03-01 Almirall Lab Nuevas anilinas.

Also Published As

Publication number Publication date
DK397383A (da) 1984-03-02
FI833075A0 (fi) 1983-08-30
EP0104423B1 (de) 1986-05-21
GR79627B (es) 1984-10-31
EP0104423A1 (de) 1984-04-04
JPS5965047A (ja) 1984-04-13
PT77231A (en) 1983-09-01
IL69598A0 (en) 1983-11-30
IL69598A (en) 1986-10-31
AU1857083A (en) 1984-03-08
FI833075A (fi) 1984-03-02
ZA836450B (en) 1984-05-30
DK397383D0 (da) 1983-08-31
ES525256A0 (es) 1984-05-16
PT77231B (en) 1986-02-04
DE3363593D1 (en) 1986-06-26
KR840006324A (ko) 1984-11-29
ATE19870T1 (de) 1986-06-15
DE3232462A1 (de) 1984-03-01
JPH0253430B2 (es) 1990-11-16
US4567188A (en) 1986-01-28

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