ES8402839A1 - Procedimiento para la obtencion de nuevos poliazaheterociclicos policiclicos. - Google Patents

Procedimiento para la obtencion de nuevos poliazaheterociclicos policiclicos.

Info

Publication number
ES8402839A1
ES8402839A1 ES515695A ES515695A ES8402839A1 ES 8402839 A1 ES8402839 A1 ES 8402839A1 ES 515695 A ES515695 A ES 515695A ES 515695 A ES515695 A ES 515695A ES 8402839 A1 ES8402839 A1 ES 8402839A1
Authority
ES
Spain
Prior art keywords
lower alkyl
polyazaheterocycles
pharmaceutical preparations
preparations containing
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES515695A
Other languages
English (en)
Other versions
ES515695A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES515695A0 publication Critical patent/ES515695A0/es
Publication of ES8402839A1 publication Critical patent/ES8402839A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/76—Nitrogen atoms to which a second hetero atom is attached
    • C07D213/77—Hydrazine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE LA QUINOXALINA POLIAZAHETEROCICLICOS, DE FORMULA GENERAL (I).CONSISTE EN HACER REACCIONAR UN ESTER REACTIVO DE UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE R3, R4, R5 Y AR TIENEN LOS SIGNIFICADOS YA MENCIONADOS, CON UN COMPUESTO DE FORMULA GENERAL (III), EN LA QUE R1 Y R2 TIENEN LOS SIGNIFICADOS YA MENCIONADOS.DE APLICACION EN LA OBTENCION DE PREPARADOS FARMACEUTICOS UTILIZADOS COMO ANTIDEPRESIVOS O COMO ANXIOLITICOS.
ES515695A 1981-09-16 1982-09-14 Procedimiento para la obtencion de nuevos poliazaheterociclicos policiclicos. Expired ES8402839A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH597581 1981-09-16

Publications (2)

Publication Number Publication Date
ES515695A0 ES515695A0 (es) 1984-03-01
ES8402839A1 true ES8402839A1 (es) 1984-03-01

Family

ID=4302388

Family Applications (1)

Application Number Title Priority Date Filing Date
ES515695A Expired ES8402839A1 (es) 1981-09-16 1982-09-14 Procedimiento para la obtencion de nuevos poliazaheterociclicos policiclicos.

Country Status (11)

Country Link
EP (1) EP0074929A1 (es)
JP (1) JPS5862173A (es)
AU (1) AU8840282A (es)
DK (1) DK411982A (es)
ES (1) ES8402839A1 (es)
FI (1) FI823156L (es)
GB (1) GB2106109B (es)
GR (1) GR76727B (es)
NO (1) NO823132L (es)
PT (1) PT75561B (es)
ZA (1) ZA826757B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8528234D0 (en) * 1985-11-15 1985-12-18 Wyeth John & Brother Ltd Heterocyclic compounds
EP0244948A3 (en) * 1986-04-30 1989-03-15 Schering Agrochemicals Limited Triazolopyrimidine herbicides
US6025489A (en) * 1989-11-17 2000-02-15 Schering Aktiengesellschaft Tricyclic pteridinones and a process for their preparation
US5854419A (en) * 1989-11-17 1998-12-29 Schering Aktiengesellschaft Tricyclic pteridinones and a process for their preparation
US5602252A (en) * 1989-11-17 1997-02-11 Berlex Laboratories, Inc. Tricyclic pteridinones and a process for their preparation
FR2696466B1 (fr) * 1992-10-02 1994-11-25 Rhone Poulenc Rorer Sa Dérivés de 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant.
EP1380298A3 (en) * 1996-05-23 2004-04-07 Bristol-Myers Squibb Pharma Company Tetrahydropteridines and pyridylpiperazines for treatment of neurological disorders, anorexia, inflammation
ZA973884B (en) * 1996-05-23 1998-11-06 Du Pont Merck Pharma Tetrahydropteridines and pyridylpiperazines for treatment of neurological disorders

Also Published As

Publication number Publication date
ES515695A0 (es) 1984-03-01
GB2106109A (en) 1983-04-07
FI823156A0 (fi) 1982-09-13
AU8840282A (en) 1983-03-24
DK411982A (da) 1983-03-17
JPS5862173A (ja) 1983-04-13
GB2106109B (en) 1985-06-12
NO823132L (no) 1983-03-17
PT75561A (en) 1982-10-01
EP0074929A1 (de) 1983-03-23
PT75561B (en) 1985-12-09
FI823156L (fi) 1983-03-17
ZA826757B (en) 1983-07-27
GR76727B (es) 1984-08-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010402