ID30502A - Senyawa heteroaromatik bisiklik yang berguna sebagai agonis lh - Google Patents

Senyawa heteroaromatik bisiklik yang berguna sebagai agonis lh

Info

Publication number
ID30502A
ID30502A IDW00200102449A ID20012449A ID30502A ID 30502 A ID30502 A ID 30502A ID W00200102449 A IDW00200102449 A ID W00200102449A ID 20012449 A ID20012449 A ID 20012449A ID 30502 A ID30502 A ID 30502A
Authority
ID
Indonesia
Prior art keywords
agonists
heteroaromatic compounds
combined
combined heteroaromatic
compounds
Prior art date
Application number
IDW00200102449A
Other languages
English (en)
Indonesian (id)
Inventor
Gerilldina Geziena Gerritsma
Nicole Corine Renee Va Straten
Anton Egbert Peter Adang
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of ID30502A publication Critical patent/ID30502A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
IDW00200102449A 1999-04-08 2000-04-03 Senyawa heteroaromatik bisiklik yang berguna sebagai agonis lh ID30502A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99201152 1999-04-08

Publications (1)

Publication Number Publication Date
ID30502A true ID30502A (id) 2001-12-13

Family

ID=8240094

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW00200102449A ID30502A (id) 1999-04-08 2000-04-03 Senyawa heteroaromatik bisiklik yang berguna sebagai agonis lh

Country Status (30)

Country Link
US (2) US6569863B1 (hu)
EP (1) EP1171443B1 (hu)
JP (1) JP4854856B2 (hu)
KR (1) KR100691546B1 (hu)
CN (1) CN1177848C (hu)
AR (1) AR028474A1 (hu)
AT (1) ATE299507T1 (hu)
AU (1) AU772258B2 (hu)
BR (1) BRPI0009558B1 (hu)
CA (1) CA2368834C (hu)
CO (1) CO5160348A1 (hu)
CZ (1) CZ300832B6 (hu)
DE (1) DE60021262T2 (hu)
DK (1) DK1171443T3 (hu)
ES (1) ES2245304T3 (hu)
HK (1) HK1041266B (hu)
HU (1) HU229002B1 (hu)
ID (1) ID30502A (hu)
IL (2) IL145483A0 (hu)
MX (1) MXPA01010144A (hu)
NO (1) NO328826B1 (hu)
NZ (1) NZ514445A (hu)
PE (1) PE20010030A1 (hu)
PL (1) PL219316B1 (hu)
PT (1) PT1171443E (hu)
RU (1) RU2248979C2 (hu)
TR (1) TR200102839T2 (hu)
TW (1) TW564247B (hu)
WO (1) WO2000061586A1 (hu)
ZA (1) ZA200107917B (hu)

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DE60132607T2 (de) * 2000-09-22 2009-01-29 N.V. Organon Bicyclische heteroaromatische verbindungen
GB0100622D0 (en) 2001-01-10 2001-02-21 Vernalis Res Ltd Chemical compounds V111
DE10108481A1 (de) 2001-02-22 2002-10-24 Bayer Ag Pyridylpyrimidine
TWI228508B (en) * 2001-09-04 2005-03-01 Akzo Nobel Nv Thieno[2,3-d]pyrimidines with combined LH and FSH agonistic activity
DK1427734T3 (da) * 2001-09-04 2006-03-06 Akzo Nobel Nv Glycin-substituerede thieno[2,3-d]pydimidiner med kombineret LH- og FSH-agonistisk aktivitet
US6974870B2 (en) 2002-06-06 2005-12-13 Boehringer Ingelheim Phamaceuticals, Inc. Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
AU2003237330A1 (en) 2002-06-06 2003-12-22 Boehringer Ingelheim Pharmaceuticals, Inc. Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
WO2004092177A1 (en) 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolopyrazines and methods of making and using the same
WO2004092170A2 (en) 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolotriazines and pyrazolotriazines useful as a2a adenosine receptor antagon ists
ATE418555T1 (de) 2003-04-09 2009-01-15 Biogen Idec Inc A2a-adenosinrezeptorantagonisten
WO2005019225A1 (ja) * 2003-08-21 2005-03-03 Kyorin Pharmaceutical Co., Ltd. Ｎｋ１受容体拮抗作用を有する化合物の製造方法及びその製造中間体
US7550485B2 (en) * 2003-10-14 2009-06-23 Wyeth Substituted N-heterocycle derivatives and methods of their use
EP1678168B1 (en) * 2003-10-24 2012-07-11 Exelixis, Inc. P70s6 kinase modulators and method of use
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
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CA2630920A1 (en) * 2005-11-22 2007-05-31 University Of South Florida Inhibition of cell proliferation
AR059898A1 (es) 2006-03-15 2008-05-07 Janssen Pharmaceutica Nv Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
WO2007136776A2 (en) * 2006-05-17 2007-11-29 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pyrimidine low molecular weight ligands for modulating hormone receptors
JP2009539865A (ja) 2006-06-06 2009-11-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 置換３−アミノ−チエノ［２，３−ｂ］ピリジン２−カルボン酸アミド化合物及び製造方法及びそれらの使用
RU2444524C2 (ru) * 2006-08-21 2012-03-10 Дженентек, Инк. Азабензотиофенильные соединения и способы применения
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
NZ584152A (en) 2007-09-14 2011-11-25 Ortho Mcneil Janssen Pharm 1,3-disubstituted 4-(aryl-x-phenyl)-1h-pyridin-2-ones
JP5433579B2 (ja) * 2007-09-14 2014-03-05 ジャンセン ファーマシューティカルズ， インコーポレイテッド． １，３−二置換−４−フェニル−１ｈ−ピリジン−２−オン
PT2203439E (pt) 2007-09-14 2011-02-11 Ortho Mcneil Janssen Pharm 4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridinil-2'- onas 1',3'-dissubstituídas
EP2205608B1 (en) * 2007-10-18 2013-05-08 Boehringer Ingelheim International GmbH Preparation of dihydrothieno[3, 2-d]pyrimidines and intermediates used therein
MX2010005110A (es) 2007-11-14 2010-09-09 Ortho Mcneil Janssen Pharm Derivados de imidazo[1,2-a]piridina y su uso como moduladores alostericos positivos de los receptores de glutamato metabotropico 2.
BRPI0918055A2 (pt) 2008-09-02 2015-12-01 Addex Pharmaceuticals Sa derivados de 3-azabiciclo[3,1,0]hexila como moduladores de receptores metabotrópicos de glutamato.
CA2738849C (en) 2008-10-16 2016-06-28 Addex Pharma S.A. Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors
JP5690277B2 (ja) 2008-11-28 2015-03-25 ジャンセン ファーマシューティカルズ， インコーポレイテッド． 代謝型グルタミン酸受容体の調節因子としてのインドールおよびベンゾオキサジン誘導体
MY153913A (en) 2009-05-12 2015-04-15 Janssen Pharmaceuticals Inc 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
NZ596078A (en) 2009-05-12 2013-06-28 Janssen Pharmaceuticals Inc 1,2,4-TRIAZOLO [4,3-a] PYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OR PREVENTION OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS
CN102439015B (zh) 2009-05-12 2015-05-13 杨森制药有限公司 1,2,4-三唑并[4,3-a]吡啶衍生物和其作为mGluR2受体的正向变构调节剂的用途
US8993591B2 (en) 2010-11-08 2015-03-31 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a] pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors
CA2814998C (en) 2010-11-08 2019-10-29 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
US9271967B2 (en) 2010-11-08 2016-03-01 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
EP2734239A2 (en) 2011-07-18 2014-05-28 Arts Biologics A/S Long acting luteinizing hormone (lh) compound
ES2575143T3 (es) 2011-11-23 2016-06-24 Cancer Research Technology Limited Inhibidores de tienopiridina de la proteína quinasa C atípica
JO3368B1 (ar) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
SI3096790T1 (sl) 2014-01-21 2019-11-29 Janssen Pharmaceutica Nv Kombinacije, ki vsebujejo pozitivne aleostrične modulatorje ali ortosterične agoniste metabotropnega glutamatergičnega receptorja podtipa 2 in njihova uporaba
ME03518B (me) 2014-01-21 2020-04-20 Janssen Pharmaceutica Nv Kombinacije koje obuhvataju pozitivne alosterične modulatore ili ortosterične agoniste metabotropnog glutamatergičnog receptora podtipa 2 i njihova primjena
CN107602585A (zh) * 2017-10-23 2018-01-19 遵义医学院 噻吩并吡啶双杂环化合物的制备工艺
BR102019022529A2 (pt) * 2019-10-25 2021-05-04 Anhanguera Educacional Ltda. Processo para obtenção de composições farmacêuticas antitumorais através de butadienos push-pull, compostos e seus usos

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Also Published As

Publication number Publication date
JP2002541259A (ja) 2002-12-03
HK1041266B (zh) 2005-09-16
NO328826B1 (no) 2010-05-25
CN1177848C (zh) 2004-12-01
EP1171443B1 (en) 2005-07-13
PL219316B1 (pl) 2015-04-30
AR028474A1 (es) 2003-05-14
TR200102839T2 (tr) 2002-04-22
ZA200107917B (en) 2003-09-23
HUP0200653A2 (en) 2002-06-29
AU772258B2 (en) 2004-04-22
NZ514445A (en) 2003-07-25
CN1349535A (zh) 2002-05-15
PL350964A1 (en) 2003-02-24
RU2248979C2 (ru) 2005-03-27
IL145483A0 (en) 2002-06-30
EP1171443A1 (en) 2002-01-16
CZ300832B6 (cs) 2009-08-19
US20030212081A1 (en) 2003-11-13
ES2245304T3 (es) 2006-01-01
US6841553B2 (en) 2005-01-11
BRPI0009558B1 (pt) 2016-10-25
DE60021262D1 (de) 2005-08-18
DK1171443T3 (da) 2005-11-07
AU3816600A (en) 2000-11-14
JP4854856B2 (ja) 2012-01-18
TW564247B (en) 2003-12-01
KR20010103801A (ko) 2001-11-23
IL145483A (en) 2007-06-03
BR0009558A (pt) 2002-02-19
CO5160348A1 (es) 2002-05-30
DE60021262T2 (de) 2006-01-05
CA2368834A1 (en) 2000-10-19
HUP0200653A3 (en) 2004-07-28
PE20010030A1 (es) 2001-01-27
KR100691546B1 (ko) 2007-03-12
NO20014824D0 (no) 2001-10-04
HU229002B1 (en) 2013-07-29
US6569863B1 (en) 2003-05-27
CZ20013605A3 (cs) 2002-03-13
MXPA01010144A (es) 2002-04-24
CA2368834C (en) 2009-11-03
ATE299507T1 (de) 2005-07-15
NO20014824L (no) 2001-10-04
WO2000061586A1 (en) 2000-10-19
PT1171443E (pt) 2005-11-30
HK1041266A1 (en) 2002-07-05

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