ID28953A - 4-(aminometil)-piperidina benzamida untuk mengobati gangguan gastrointestinal - Google Patents

4-(aminometil)-piperidina benzamida untuk mengobati gangguan gastrointestinal

Info

Publication number
ID28953A
ID28953A IDW00200101336A ID20011336A ID28953A ID 28953 A ID28953 A ID 28953A ID W00200101336 A IDW00200101336 A ID W00200101336A ID 20011336 A ID20011336 A ID 20011336A ID 28953 A ID28953 A ID 28953A
Authority
ID
Indonesia
Prior art keywords
aminometyl
benzamide
piperidine
gastrointestinal disorders
treat gastrointestinal
Prior art date
Application number
IDW00200101336A
Other languages
English (en)
Indonesian (id)
Inventor
J P R M A Bosmans
Ann L G Meulemans
M A J De Cleyn
H J M Gijsen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ID28953A publication Critical patent/ID28953A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IDW00200101336A 1998-12-22 1999-12-14 4-(aminometil)-piperidina benzamida untuk mengobati gangguan gastrointestinal ID28953A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98204411 1998-12-22

Publications (1)

Publication Number Publication Date
ID28953A true ID28953A (id) 2001-07-19

Family

ID=8234539

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW00200101336A ID28953A (id) 1998-12-22 1999-12-14 4-(aminometil)-piperidina benzamida untuk mengobati gangguan gastrointestinal

Country Status (34)

Country Link
US (2) US6544997B1 (cs)
EP (1) EP1140915B1 (cs)
JP (1) JP4615725B2 (cs)
KR (1) KR100633680B1 (cs)
CN (1) CN1150190C (cs)
AR (1) AR024240A1 (cs)
AT (1) ATE297917T1 (cs)
AU (1) AU770397B2 (cs)
BG (1) BG64953B1 (cs)
BR (1) BR9916491A (cs)
CA (1) CA2355857C (cs)
CZ (1) CZ300851B6 (cs)
DE (1) DE69925865T2 (cs)
DK (1) DK1140915T3 (cs)
EA (1) EA003608B1 (cs)
EE (1) EE200100335A (cs)
ES (1) ES2245131T3 (cs)
HK (1) HK1039114B (cs)
HR (1) HRP20010445A2 (cs)
HU (1) HUP0104838A3 (cs)
ID (1) ID28953A (cs)
IL (1) IL143858A (cs)
MY (1) MY121852A (cs)
NO (1) NO321324B1 (cs)
NZ (1) NZ512871A (cs)
PL (1) PL197409B1 (cs)
PT (1) PT1140915E (cs)
SI (1) SI1140915T1 (cs)
SK (1) SK285829B6 (cs)
TR (1) TR200101962T2 (cs)
TW (1) TW570920B (cs)
UA (1) UA71591C2 (cs)
WO (1) WO2000037461A1 (cs)
ZA (1) ZA200105135B (cs)

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AU2002335161A1 (en) * 2002-09-12 2004-04-30 Nagase Chemtex Corporation Medicinal composition
CA2528653C (en) * 2003-06-19 2012-01-10 Janssen Pharmaceutica N.V. Hydroxycarbonylphenyl substituted 4-(aminomethyl)-piperidine benzamides as 5ht4-antagonists
EP1641783B1 (en) 2003-06-19 2012-03-28 Janssen Pharmaceutica NV Aminosulfonyl substituted 4-(aminomethyl)-piperidine benzamides as 5ht4-antagonists
KR20060022702A (ko) 2003-06-19 2006-03-10 얀센 파마슈티카 엔.브이. 5ht4-길항성 4-(아미노메틸)-피페리딘벤즈아미드
JO2478B1 (en) 2003-06-19 2009-01-20 جانسين فارماسوتيكا ان. في. (Aminomethyl) -biperidine benzamides as 5 HT4 antagonists
AU2004254190B2 (en) 2003-06-19 2010-04-22 Janssen Pharmaceutica N.V. Heterocyclic substituted 4-(aminomethyl)-piperidine benzamides as 5HT4-antagonists
PT1664036E (pt) 2003-09-03 2012-02-16 Pfizer Compostos de benzimidazolona que possuem actividade agonística do receptor 5-ht4
DE602004026095D1 (de) * 2003-11-24 2010-04-29 Pfizer Chinoloncarbonsäureverbindungen mit 5-ht4-rezeptoragonistischer wirkung
TW200533348A (en) * 2004-02-18 2005-10-16 Theravance Inc Indazole-carboxamide compounds as 5-ht4 receptor agonists
US7728006B2 (en) * 2004-04-07 2010-06-01 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
US8309575B2 (en) 2004-04-07 2012-11-13 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
TWI351282B (en) 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
EA200801608A1 (ru) 2004-06-15 2008-10-30 Пфайзер Инк. Производные бензимидазолонкарбоновой кислоты
US20060035890A1 (en) * 2004-08-10 2006-02-16 Amit Banerjee Compounds and methods for the treatment of ubiquitin conjugating disorders
US7399862B2 (en) * 2004-11-05 2008-07-15 Theravance, Inc. 5-HT4 receptor agonist compounds
WO2006052889A2 (en) * 2004-11-05 2006-05-18 Theravance, Inc. Quinolinone-carboxamide compounds
ES2347265T3 (es) * 2004-12-22 2010-10-27 Theravance, Inc. Compuestos de indazol-carboxamida.
MX2007010769A (es) * 2005-03-02 2008-03-07 Theravance Inc Compuestos de quinolina como agonistas de receptor 5-ht4.
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
US8377968B2 (en) 2008-06-02 2013-02-19 Zalicus Pharmaceuticals, Ltd. N-piperidinyl acetamide derivatives as calcium channel blockers
US10208023B2 (en) 2013-03-01 2019-02-19 Mark G. DeGiacomo Heterocyclic inhibitors of the sodium channel
US20180305334A1 (en) * 2015-10-14 2018-10-25 Aquinnah Pharmaceuticals, Inc. Compounds, compositions and methods of use against stress granules
JP2022540253A (ja) 2019-07-11 2022-09-14 プラクシス プレシジョン メディシンズ, インコーポレイテッド T型カルシウムチャネル調節因子の製剤およびその使用方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ225152A (en) * 1987-07-17 1990-04-26 Janssen Pharmaceutica Nv Heterocyclically substituted piperidinyl benzamides as pharmaceuticals
CA1317940C (en) * 1987-09-25 1993-05-18 Georges H. P. Van Daele Substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides
US5374637A (en) * 1989-03-22 1994-12-20 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
JPH06510283A (ja) 1991-08-20 1994-11-17 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 5−ht4レセプター拮抗薬
JP3294611B2 (ja) * 1991-09-12 2002-06-24 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 5−ht4レセプター・アンタゴニスト
DK0577847T3 (da) * 1992-01-23 1999-06-23 Toray Industries Morphinanderivat og medicinsk anvendelse deraf
JPH07503480A (ja) * 1992-02-06 1995-04-13 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 5−ht4拮抗薬としてのベンゾピラン,ベンゾチオピランおよびベンゾフラン誘導体
GB9219163D0 (en) 1992-09-10 1992-10-28 Smithkline Beecham Plc Pharmaceuticals
JPH08502273A (ja) 1992-10-13 1996-03-12 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 5−ht▲下4▼レセプターアンタゴニスト用複素環式エステルまたはアミド
MX9306311A (es) 1992-10-13 1994-04-29 Smithkline Beecham Plc Compuestos antagonistas del receptor de 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que los contienen
NZ257545A (en) 1992-11-05 1997-01-29 Smithkline Beecham Plc Heterocyclic (especially piperidine) derivatives and pharmaceutical compositions
GB9301660D0 (en) * 1993-01-28 1993-03-17 Smithkline Beecham Plc Pharmaceuticals
GB9312348D0 (en) 1993-06-16 1993-07-28 Smithkline Beecham Plc Pharmaceuticals
ES2103675B1 (es) * 1995-01-10 1998-07-01 Almirall Lab Nuevas piperidinas sustituidas.
IT1275903B1 (it) 1995-03-14 1997-10-24 Boehringer Ingelheim Italia Esteri e ammidi della 1,4-piperidina disostituita
GB9507882D0 (en) 1995-04-18 1995-05-31 Pharmacia Spa Substituted dihydrobenzofuran derivatives as 5-ht4 agonists
KR100469029B1 (ko) * 1996-02-15 2005-05-27 얀센 파마슈티카 엔.브이. 세로토닌재흡수억제제의위장효과를극복하기위한5ht4수용체길항제의용도
TW445263B (en) * 1996-02-29 2001-07-11 Janssen Pharmaceutica Nv Novel esters of 1,4-disubstituted piperidine derivatives
TW402591B (en) * 1997-07-11 2000-08-21 Janssen Pharmaceutica Nv Monocyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives
EP1112270B1 (en) * 1998-09-10 2007-03-21 F. Hoffmann-La Roche Ag Dihydrobenzodioxine carboxamide and ketone derivatives as 5-ht4 receptor antagonists
DE10217868A1 (de) * 2002-04-22 2003-10-30 Jomed N V Ballon-Katheter

Also Published As

Publication number Publication date
EA003608B1 (ru) 2003-06-26
CN1331690A (zh) 2002-01-16
US6544997B1 (en) 2003-04-08
BR9916491A (pt) 2001-09-04
MY121852A (en) 2006-02-28
WO2000037461A1 (en) 2000-06-29
US20030181456A1 (en) 2003-09-25
US7205410B2 (en) 2007-04-17
AU2432800A (en) 2000-07-12
JP4615725B2 (ja) 2011-01-19
SK285829B6 (sk) 2007-09-06
ATE297917T1 (de) 2005-07-15
NO321324B1 (no) 2006-04-24
SK8592001A3 (en) 2002-02-05
TW570920B (en) 2004-01-11
IL143858A (en) 2005-03-20
IL143858A0 (en) 2002-04-21
UA71591C2 (en) 2004-12-15
JP2002533337A (ja) 2002-10-08
CA2355857C (en) 2008-10-28
BG105571A (en) 2002-01-31
HK1039114A1 (en) 2002-04-12
AR024240A1 (es) 2002-09-25
NO20012858L (no) 2001-06-08
HRP20010445A2 (en) 2002-06-30
KR100633680B1 (ko) 2006-10-11
CZ20012117A3 (cs) 2001-10-17
HUP0104838A2 (hu) 2002-07-29
PT1140915E (pt) 2005-11-30
PL348417A1 (en) 2002-05-20
DK1140915T3 (da) 2005-10-10
EA200100710A1 (ru) 2001-12-24
NZ512871A (en) 2002-11-26
CZ300851B6 (cs) 2009-08-26
DE69925865D1 (de) 2005-07-21
NO20012858D0 (no) 2001-06-08
HK1039114B (en) 2005-08-19
TR200101962T2 (tr) 2002-04-22
BG64953B1 (bg) 2006-10-31
EP1140915B1 (en) 2005-06-15
CN1150190C (zh) 2004-05-19
EP1140915A1 (en) 2001-10-10
CA2355857A1 (en) 2000-06-29
AU770397B2 (en) 2004-02-19
EE200100335A (et) 2002-08-15
HUP0104838A3 (en) 2003-05-28
ES2245131T3 (es) 2005-12-16
PL197409B1 (pl) 2008-03-31
KR20010080293A (ko) 2001-08-22
ZA200105135B (en) 2002-06-21
SI1140915T1 (sl) 2005-12-31
DE69925865T2 (de) 2006-05-11

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