DE60300021D1 - (S)-4-Amino-5-Chloro-2-Methoxy-N-[1-[1-(2-Tetrahydrofuryl-Carbonyl)-4-Piperidinylmethyl]-4-Piperidinyl]benzamid zur Behandlung von Magen-Darmbewegungskrankheiten - Google Patents

(S)-4-Amino-5-Chloro-2-Methoxy-N-[1-[1-(2-Tetrahydrofuryl-Carbonyl)-4-Piperidinylmethyl]-4-Piperidinyl]benzamid zur Behandlung von Magen-Darmbewegungskrankheiten

Info

Publication number
DE60300021D1
DE60300021D1 DE60300021T DE60300021T DE60300021D1 DE 60300021 D1 DE60300021 D1 DE 60300021D1 DE 60300021 T DE60300021 T DE 60300021T DE 60300021 T DE60300021 T DE 60300021T DE 60300021 D1 DE60300021 D1 DE 60300021D1
Authority
DE
Germany
Prior art keywords
tetrahydrofurylcarbonyl
piperidinylmethyl
benzamide
piperidinyl
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60300021T
Other languages
English (en)
Other versions
DE60300021T2 (de
Inventor
Shiro Kato
Hiroshi Yamazaki
Yoshimi Hirokawa
Yoko Kan
Naoyuki Yoshida
Kazuo Morikage
Yukiko Morikage
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dainippon Pharmaceutical Co Ltd
Original Assignee
Dainippon Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co Ltd filed Critical Dainippon Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE60300021D1 publication Critical patent/DE60300021D1/de
Publication of DE60300021T2 publication Critical patent/DE60300021T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE60300021T 2002-05-16 2003-01-03 que- Expired - Fee Related DE60300021T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002141262 2002-05-16
JP2002141262 2002-05-16

Publications (2)

Publication Number Publication Date
DE60300021D1 true DE60300021D1 (de) 2004-09-16
DE60300021T2 DE60300021T2 (de) 2005-09-08

Family

ID=29267809

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60300021T Expired - Fee Related DE60300021T2 (de) 2002-05-16 2003-01-03 que-

Country Status (27)

Country Link
US (1) US6696468B2 (de)
EP (1) EP1362857B1 (de)
JP (1) JP3643107B2 (de)
KR (1) KR20040107520A (de)
CN (1) CN1653063A (de)
AR (1) AR040021A1 (de)
AT (1) ATE273304T1 (de)
AU (1) AU2003230245A1 (de)
BR (1) BR0309933A (de)
CA (1) CA2483368A1 (de)
CZ (1) CZ20041084A3 (de)
DE (1) DE60300021T2 (de)
DK (1) DK1362857T3 (de)
ES (1) ES2227500T3 (de)
HK (1) HK1060118A1 (de)
HU (1) HUP0501016A2 (de)
IL (1) IL165012A0 (de)
MX (1) MXPA04011332A (de)
NO (1) NO20045469L (de)
PL (1) PL372724A1 (de)
PT (1) PT1362857E (de)
RU (1) RU2004136853A (de)
SK (1) SK50192004A3 (de)
TR (1) TR200403020T2 (de)
TW (1) TW200400186A (de)
WO (1) WO2003097638A1 (de)
ZA (1) ZA200409053B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904377D0 (sv) * 1999-12-01 1999-12-01 Astra Pharma Prod Pharmaceutical combinations
SE0200843D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0200844D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0300957D0 (sv) 2003-04-01 2003-04-01 Astrazeneca Ab Chemical compounds
TW200533348A (en) * 2004-02-18 2005-10-16 Theravance Inc Indazole-carboxamide compounds as 5-ht4 receptor agonists
TWI351282B (en) 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
US7728006B2 (en) * 2004-04-07 2010-06-01 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
US8309575B2 (en) 2004-04-07 2012-11-13 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
US7396933B2 (en) * 2004-11-05 2008-07-08 Theravance, Inc. Quinolinone-carboxamide compounds
EP1807422B1 (de) * 2004-11-05 2009-09-02 Theravance, Inc. 5-HT4-Rezeptoragonistenverbindungen
ATE469897T1 (de) * 2004-12-22 2010-06-15 Theravance Inc Indazolcarbonsäureamidverbindungen
BRPI0608392A2 (pt) * 2005-03-02 2009-12-29 Theravance Inc compostos de quinolinona como agonistas do receptor 5-ht4
MY147756A (en) 2005-05-25 2013-01-15 Theravance Inc Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists
US7256294B2 (en) * 2005-05-25 2007-08-14 Theravance, Inc. Crystalline form of a benzimidazole-carboxamide medicinal compound
US20080200505A1 (en) * 2005-05-27 2008-08-21 Astrazeneca Ab Piperidines for the Treatment of Chemokine Mediated Diseases
TW200722419A (en) * 2005-05-27 2007-06-16 Astrazeneca Ab Chemical compounds
US8314127B2 (en) 2005-07-21 2012-11-20 Astrazeneca Ab Piperidine derivatives
GB0525068D0 (en) 2005-12-08 2006-01-18 Novartis Ag Organic compounds
TWI423967B (zh) * 2008-02-21 2014-01-21 Dainippon Sumitomo Pharma Co 醯胺衍生物及含有其之醫藥組合物
US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
WO2011092293A2 (en) 2010-02-01 2011-08-04 Novartis Ag Cyclohexyl amide derivatives as crf receptor antagonists
AR080055A1 (es) 2010-02-01 2012-03-07 Novartis Ag Derivados de pirazolo-[5,1-b]-oxazol como antagonistas de los receptores de crf -1
JP5748777B2 (ja) 2010-02-02 2015-07-15 ノバルティス アーゲー Ｃｒｆ受容体アンタゴニストとしてのシクロヘキシルアミド誘導体
US8546416B2 (en) 2011-05-27 2013-10-01 Novartis Ag 3-spirocyclic piperidine derivatives as ghrelin receptor agonists
AU2013255458A1 (en) 2012-05-03 2014-10-09 Novartis Ag L-malate salt of 2, 7 - diaza - spiro [4.5 ] dec- 7 - yle derivatives and crystalline forms thereof as ghrelin receptor agonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH111472A (ja) 1996-04-30 1999-01-06 Dainippon Pharmaceut Co Ltd ベンズアミド誘導体及びそれを含有する医薬組成物
US6294555B1 (en) * 1998-04-28 2001-09-25 Dainippon Pharmaceutical Co., Ltd. 1-[(1-Substituted-4-piperidinyl)methyl]-4-piperidine derivative, process for producing the same, medicinal compositions containing the same and intermediates of these compounds
JP2000080081A (ja) 1998-06-24 2000-03-21 Dainippon Pharmaceut Co Ltd １―〔（１―置換―４―ピペリジニル）メチル〕―４―ピペリジン誘導体及びそれを含有する医薬組成物
JP2001122784A (ja) 1999-10-27 2001-05-08 Dainippon Pharmaceut Co Ltd １−［（１−置換−４−ピペリジニル）メチル］−４−ピペリジン誘導体からなる医薬

Also Published As

Publication number Publication date
CZ20041084A3 (cs) 2005-02-16
RU2004136853A (ru) 2005-06-27
NO20045469L (no) 2005-02-16
TR200403020T2 (tr) 2005-05-23
PT1362857E (pt) 2004-11-30
EP1362857A1 (de) 2003-11-19
DK1362857T3 (da) 2004-12-20
DE60300021T2 (de) 2005-09-08
US20030216433A1 (en) 2003-11-20
HK1060118A1 (en) 2004-07-30
AR040021A1 (es) 2005-03-09
US6696468B2 (en) 2004-02-24
WO2003097638A1 (en) 2003-11-27
EP1362857B1 (de) 2004-08-11
KR20040107520A (ko) 2004-12-20
SK50192004A3 (sk) 2005-04-01
MXPA04011332A (es) 2005-02-14
ATE273304T1 (de) 2004-08-15
JP2004043453A (ja) 2004-02-12
ES2227500T3 (es) 2005-04-01
ZA200409053B (en) 2005-07-12
TW200400186A (en) 2004-01-01
BR0309933A (pt) 2005-02-09
IL165012A0 (en) 2005-12-18
CN1653063A (zh) 2005-08-10
PL372724A1 (en) 2005-07-25
HUP0501016A2 (en) 2006-02-28
CA2483368A1 (en) 2003-11-27
JP3643107B2 (ja) 2005-04-27
AU2003230245A1 (en) 2003-12-02

Similar Documents

Publication Publication Date Title
DE60300021D1 (de) (S)-4-Amino-5-Chloro-2-Methoxy-N-[1-[1-(2-Tetrahydrofuryl-Carbonyl)-4-Piperidinylmethyl]-4-Piperidinyl]benzamid zur Behandlung von Magen-Darmbewegungskrankheiten
ATE350375T1 (de) 17beta-hydroxysteroid dehydrogenase type 3 inhibitoren zur behandlung von androgen- abhängigen erkrankungen
DE602004020072D1 (de) 1,2,3,4-tetrasubstituiertes indol zur behandlung von atemwegserkrankungen
ATE297917T1 (de) 4-(aminomethyl)-piperidinbenzamide zur behandlung von gastrointestinalen störungen
CY2013021I1 (el) Συνθεσεις για τη θεραπευτικη αγωγη γαστροεντερικων διαταραχων
ATE410430T1 (de) 2,3-dihydro-6-nitroimidazoä2,1- büoxazolverbindungen zur behandlung von tuberkulose
ATE420866T1 (de) 4-(phenylpiperazinylmethyl) benzamidderivate und deren verwendung zur behandlung von schmerzen, angst oder gastrointestinalen störungen
EA200500098A1 (ru) Лекарственное средство и способ лечения патологического синдрома
DE60204951D1 (de) Ccr5 antagonisten verwendbar für die behandlung von aids
DE60208221D1 (de) Heterozyklische verbindungen zur behandlung von harnwegserkrankungen
NO20045554L (no) Fremgangsmate for behandling av diabetes
DE60236743D1 (de) Zur behandlung androgenabhängiger krankheiten
ATE303379T1 (de) 4-(phenyl-piperidin-4-ylidenmethyl)-benzamid- derivate und deren verwendung zur behandlung von schmerzen, angst oder gastrointestinalen störungen
DE60238765D1 (de) Carbamatverbindungen zur behandlung von schmerz
DE50303208D1 (de) Osteosyntheseeinrichtung
ATE362923T1 (de) 4-(phenylpiperazinylmethyl)benzamidderivate und deren verwendung zur behandlung von schmerzen oder gastrointestinalen erkrankungen
FR2837224B1 (fr) Bonde traitante
ATE287400T1 (de) 4-(phenylpiperidin-4-ylidenmethyl) benzamidderivate und deren verwendung zur behandlung von schmerzen, angst oder gastrointestinalen störungen
DE50308460D1 (de) Verwendung von ambroxol zur behandlung von chronischen schmerzen
IL158630A0 (en) 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
ATE313528T1 (de) 4-(phenyl(piperidin-4-yl)amino) benzamidderivate und deren verwendung zur behandlung von schmerzen,angst oder gastrointestinalen störungen
ATE313529T1 (de) 4-(phenyl(piperidin-4-yl)amino) benzamidderivate und deren verwendung zur behandlung von schmerzen,angst oder gastrointestinalen störungen
IL158700A0 (en) 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
DE50211298D1 (de) N-(indolcarbonyl-)piperazinderivaten zur behandlung von fettsucht
DE60115831D1 (de) Gugulipid zur Behandlung von kognitiven Störungen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee