DK1362857T3 - (S)-4-amino-5-chlor-2-methoxy-N-[1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamid til behandling af gastrointestinale motilitetslidelser - Google Patents
(S)-4-amino-5-chlor-2-methoxy-N-[1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamid til behandling af gastrointestinale motilitetslidelserInfo
- Publication number
- DK1362857T3 DK1362857T3 DK03250050T DK03250050T DK1362857T3 DK 1362857 T3 DK1362857 T3 DK 1362857T3 DK 03250050 T DK03250050 T DK 03250050T DK 03250050 T DK03250050 T DK 03250050T DK 1362857 T3 DK1362857 T3 DK 1362857T3
- Authority
- DK
- Denmark
- Prior art keywords
- tetrahydrofurylcarbonyl
- piperidinylmethyl
- benzamide
- piperidinyl
- chloro
- Prior art date
Links
- MMAHZLJRNLZQCI-NRFANRHFSA-N 4-amino-5-chloro-2-methoxy-n-[1-[[1-[(2s)-oxolane-2-carbonyl]piperidin-4-yl]methyl]piperidin-4-yl]benzamide Chemical compound COC1=CC(N)=C(Cl)C=C1C(=O)NC1CCN(CC2CCN(CC2)C(=O)[C@H]2OCCC2)CC1 MMAHZLJRNLZQCI-NRFANRHFSA-N 0.000 title 1
- 208000017228 Gastrointestinal motility disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002141262 | 2002-05-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1362857T3 true DK1362857T3 (da) | 2004-12-20 |
Family
ID=29267809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03250050T DK1362857T3 (da) | 2002-05-16 | 2003-01-03 | (S)-4-amino-5-chlor-2-methoxy-N-[1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamid til behandling af gastrointestinale motilitetslidelser |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6696468B2 (da) |
| EP (1) | EP1362857B1 (da) |
| JP (1) | JP3643107B2 (da) |
| KR (1) | KR20040107520A (da) |
| CN (1) | CN1653063A (da) |
| AR (1) | AR040021A1 (da) |
| AT (1) | ATE273304T1 (da) |
| AU (1) | AU2003230245A1 (da) |
| BR (1) | BR0309933A (da) |
| CA (1) | CA2483368A1 (da) |
| CZ (1) | CZ20041084A3 (da) |
| DE (1) | DE60300021T2 (da) |
| DK (1) | DK1362857T3 (da) |
| ES (1) | ES2227500T3 (da) |
| HU (1) | HUP0501016A2 (da) |
| IL (1) | IL165012A0 (da) |
| MX (1) | MXPA04011332A (da) |
| NO (1) | NO20045469L (da) |
| PL (1) | PL372724A1 (da) |
| PT (1) | PT1362857E (da) |
| RU (1) | RU2004136853A (da) |
| SK (1) | SK50192004A3 (da) |
| TR (1) | TR200403020T2 (da) |
| TW (1) | TW200400186A (da) |
| WO (1) | WO2003097638A1 (da) |
| ZA (1) | ZA200409053B (da) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9904377D0 (sv) * | 1999-12-01 | 1999-12-01 | Astra Pharma Prod | Pharmaceutical combinations |
| SE0200843D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
| SE0200844D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
| SE0300957D0 (sv) | 2003-04-01 | 2003-04-01 | Astrazeneca Ab | Chemical compounds |
| TW200533348A (en) * | 2004-02-18 | 2005-10-16 | Theravance Inc | Indazole-carboxamide compounds as 5-ht4 receptor agonists |
| US7728006B2 (en) * | 2004-04-07 | 2010-06-01 | Theravance, Inc. | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
| TWI351282B (en) | 2004-04-07 | 2011-11-01 | Theravance Inc | Quinolinone-carboxamide compounds as 5-ht4 recepto |
| US8309575B2 (en) | 2004-04-07 | 2012-11-13 | Theravance, Inc. | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
| ES2332808T3 (es) * | 2004-11-05 | 2010-02-12 | Theravance, Inc. | Compuestos agonistas del receptor 5-ht4. |
| EP1807423B1 (en) * | 2004-11-05 | 2009-05-20 | Theravance, Inc. | Quinolinone-carboxamide compounds |
| MX2007007818A (es) * | 2004-12-22 | 2007-09-11 | Theravance Inc | Compuestos de indazol-carboxamida. |
| ES2523851T3 (es) * | 2005-03-02 | 2014-12-02 | Theravance Biopharma R&D Ip, Llc | Compuestos de quinolinona como agonistas de los receptores 5-HT4 |
| US7256294B2 (en) * | 2005-05-25 | 2007-08-14 | Theravance, Inc. | Crystalline form of a benzimidazole-carboxamide medicinal compound |
| MY147756A (en) * | 2005-05-25 | 2013-01-15 | Theravance Inc | Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists |
| WO2006126948A1 (en) * | 2005-05-27 | 2006-11-30 | Astrazeneca Ab | Piperidines for the treatment of chemokine mediated diseases |
| TW200722419A (en) * | 2005-05-27 | 2007-06-16 | Astrazeneca Ab | Chemical compounds |
| EP2402316A1 (en) | 2005-07-21 | 2012-01-04 | AstraZeneca AB (Publ) | Piperidine derivatives |
| GB0525068D0 (en) | 2005-12-08 | 2006-01-18 | Novartis Ag | Organic compounds |
| TWI423967B (zh) * | 2008-02-21 | 2014-01-21 | Dainippon Sumitomo Pharma Co | 醯胺衍生物及含有其之醫藥組合物 |
| US8349852B2 (en) | 2009-01-13 | 2013-01-08 | Novartis Ag | Quinazolinone derivatives useful as vanilloid antagonists |
| CN102762572A (zh) | 2010-02-01 | 2012-10-31 | 诺瓦提斯公司 | 作为CRF-1受体拮抗剂的吡唑并[5,1b]*唑衍生物 |
| AR080056A1 (es) | 2010-02-01 | 2012-03-07 | Novartis Ag | Derivados de ciclohexil-amida como antagonistas de los receptores de crf |
| JP5748777B2 (ja) | 2010-02-02 | 2015-07-15 | ノバルティス アーゲー | Ｃｒｆ受容体アンタゴニストとしてのシクロヘキシルアミド誘導体 |
| US8546416B2 (en) | 2011-05-27 | 2013-10-01 | Novartis Ag | 3-spirocyclic piperidine derivatives as ghrelin receptor agonists |
| CA2867043A1 (en) | 2012-05-03 | 2013-11-07 | Novartis Ag | L-malate salt of 2,7-diaza-spiro[4.5]dec-7-yle derivatives and crystalline forms thereof as ghrelin receptor agonists |
| MY210588A (en) * | 2020-05-04 | 2025-10-01 | Takeda Pharmaceuticals Co | Luminally-acting n-(piperidin-4-yl)benzamide derivatives |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH111472A (ja) | 1996-04-30 | 1999-01-06 | Dainippon Pharmaceut Co Ltd | ベンズアミド誘導体及びそれを含有する医薬組成物 |
| HUP0101511A3 (en) * | 1998-04-28 | 2002-12-28 | Dainippon Pharmaceutical Co | 1-[(1-substituted-4-piperidinyl)methyl]-4-piperidine derivatives, process for producing the same, medicinal compositions containing the same and intermediates of these compounds |
| JP2000080081A (ja) | 1998-06-24 | 2000-03-21 | Dainippon Pharmaceut Co Ltd | １―〔（１―置換―４―ピペリジニル）メチル〕―４―ピペリジン誘導体及びそれを含有する医薬組成物 |
| JP2001122784A (ja) | 1999-10-27 | 2001-05-08 | Dainippon Pharmaceut Co Ltd | １−［（１−置換−４−ピペリジニル）メチル］−４−ピペリジン誘導体からなる医薬 |
-
2002
- 2002-12-18 US US10/321,615 patent/US6696468B2/en not_active Expired - Fee Related
-
2003
- 2003-01-03 AT AT03250050T patent/ATE273304T1/de not_active IP Right Cessation
- 2003-01-03 PT PT03250050T patent/PT1362857E/pt unknown
- 2003-01-03 DK DK03250050T patent/DK1362857T3/da active
- 2003-01-03 DE DE60300021T patent/DE60300021T2/de not_active Expired - Fee Related
- 2003-01-03 EP EP03250050A patent/EP1362857B1/en not_active Expired - Lifetime
- 2003-01-03 ES ES03250050T patent/ES2227500T3/es not_active Expired - Lifetime
- 2003-05-08 TW TW092112525A patent/TW200400186A/zh unknown
- 2003-05-15 TR TR2004/03020T patent/TR200403020T2/xx unknown
- 2003-05-15 PL PL03372724A patent/PL372724A1/xx not_active Application Discontinuation
- 2003-05-15 CZ CZ20041084A patent/CZ20041084A3/cs unknown
- 2003-05-15 MX MXPA04011332A patent/MXPA04011332A/es unknown
- 2003-05-15 BR BR0309933-4A patent/BR0309933A/pt not_active Application Discontinuation
- 2003-05-15 SK SK5019-2004A patent/SK50192004A3/sk unknown
- 2003-05-15 JP JP2003137413A patent/JP3643107B2/ja not_active Expired - Fee Related
- 2003-05-15 HU HU0501016A patent/HUP0501016A2/hu unknown
- 2003-05-15 CA CA002483368A patent/CA2483368A1/en not_active Abandoned
- 2003-05-15 CN CNA03811089XA patent/CN1653063A/zh active Pending
- 2003-05-15 KR KR10-2004-7018158A patent/KR20040107520A/ko not_active Withdrawn
- 2003-05-15 AU AU2003230245A patent/AU2003230245A1/en not_active Abandoned
- 2003-05-15 WO PCT/JP2003/006051 patent/WO2003097638A1/en not_active Ceased
- 2003-05-15 IL IL16501203A patent/IL165012A0/xx unknown
- 2003-05-15 AR ARP030101702A patent/AR040021A1/es unknown
- 2003-05-15 RU RU2004136853/04A patent/RU2004136853A/ru not_active Application Discontinuation
-
2004
- 2004-11-09 ZA ZA200409035A patent/ZA200409053B/en unknown
- 2004-12-15 NO NO20045469A patent/NO20045469L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003230245A1 (en) | 2003-12-02 |
| AR040021A1 (es) | 2005-03-09 |
| CZ20041084A3 (cs) | 2005-02-16 |
| ZA200409053B (en) | 2005-07-12 |
| EP1362857B1 (en) | 2004-08-11 |
| JP3643107B2 (ja) | 2005-04-27 |
| HK1060118A1 (en) | 2004-07-30 |
| EP1362857A1 (en) | 2003-11-19 |
| NO20045469L (no) | 2005-02-16 |
| TW200400186A (en) | 2004-01-01 |
| PL372724A1 (en) | 2005-07-25 |
| PT1362857E (pt) | 2004-11-30 |
| DE60300021D1 (de) | 2004-09-16 |
| ATE273304T1 (de) | 2004-08-15 |
| SK50192004A3 (sk) | 2005-04-01 |
| HUP0501016A2 (en) | 2006-02-28 |
| DE60300021T2 (de) | 2005-09-08 |
| ES2227500T3 (es) | 2005-04-01 |
| CA2483368A1 (en) | 2003-11-27 |
| US6696468B2 (en) | 2004-02-24 |
| BR0309933A (pt) | 2005-02-09 |
| IL165012A0 (en) | 2005-12-18 |
| JP2004043453A (ja) | 2004-02-12 |
| TR200403020T2 (tr) | 2005-05-23 |
| US20030216433A1 (en) | 2003-11-20 |
| MXPA04011332A (es) | 2005-02-14 |
| KR20040107520A (ko) | 2004-12-20 |
| CN1653063A (zh) | 2005-08-10 |
| WO2003097638A1 (en) | 2003-11-27 |
| RU2004136853A (ru) | 2005-06-27 |
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