HUP0501016A2 - (s)-4-amino-5-chloro-2-methoxy-n-{1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl}benzamide, process for the preparation thereof pharmaceutical composition containing the same and intermediate therefor - Google Patents

(s)-4-amino-5-chloro-2-methoxy-n-{1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl}benzamide, process for the preparation thereof pharmaceutical composition containing the same and intermediate therefor

Info

Publication number
HUP0501016A2
HUP0501016A2 HU0501016A HUP0501016A HUP0501016A2 HU P0501016 A2 HUP0501016 A2 HU P0501016A2 HU 0501016 A HU0501016 A HU 0501016A HU P0501016 A HUP0501016 A HU P0501016A HU P0501016 A2 HUP0501016 A2 HU P0501016A2
Authority
HU
Hungary
Prior art keywords
tetrahydrofurylcarbonyl
piperidinylmethyl
benzamide
piperidinyl
chloro
Prior art date
Application number
HU0501016A
Other languages
English (en)
Inventor
Shiro Kato
Hiroshi Yamazaki
Yoshimi Hirokawa
Yoko Kan
Naoyuki Yoshida
Kazuo Morikage
Yukiko Morikage
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of HUP0501016A2 publication Critical patent/HUP0501016A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU0501016A 2002-05-16 2003-05-15 (s)-4-amino-5-chloro-2-methoxy-n-{1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl}benzamide, process for the preparation thereof pharmaceutical composition containing the same and intermediate therefor HUP0501016A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002141262 2002-05-16
PCT/JP2003/006051 WO2003097638A1 (en) 2002-05-16 2003-05-15 (s)-4-amino-5-chloro-2-methoxy-n-[1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamide, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor

Publications (1)

Publication Number Publication Date
HUP0501016A2 true HUP0501016A2 (en) 2006-02-28

Family

ID=29267809

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0501016A HUP0501016A2 (en) 2002-05-16 2003-05-15 (s)-4-amino-5-chloro-2-methoxy-n-{1-[1-(2-tetrahydrofurylcarbonyl)-4-piperidinylmethyl]-4-piperidinyl}benzamide, process for the preparation thereof pharmaceutical composition containing the same and intermediate therefor

Country Status (27)

Country Link
US (1) US6696468B2 (hu)
EP (1) EP1362857B1 (hu)
JP (1) JP3643107B2 (hu)
KR (1) KR20040107520A (hu)
CN (1) CN1653063A (hu)
AR (1) AR040021A1 (hu)
AT (1) ATE273304T1 (hu)
AU (1) AU2003230245A1 (hu)
BR (1) BR0309933A (hu)
CA (1) CA2483368A1 (hu)
CZ (1) CZ20041084A3 (hu)
DE (1) DE60300021T2 (hu)
DK (1) DK1362857T3 (hu)
ES (1) ES2227500T3 (hu)
HK (1) HK1060118A1 (hu)
HU (1) HUP0501016A2 (hu)
IL (1) IL165012A0 (hu)
MX (1) MXPA04011332A (hu)
NO (1) NO20045469L (hu)
PL (1) PL372724A1 (hu)
PT (1) PT1362857E (hu)
RU (1) RU2004136853A (hu)
SK (1) SK50192004A3 (hu)
TR (1) TR200403020T2 (hu)
TW (1) TW200400186A (hu)
WO (1) WO2003097638A1 (hu)
ZA (1) ZA200409053B (hu)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904377D0 (sv) * 1999-12-01 1999-12-01 Astra Pharma Prod Pharmaceutical combinations
SE0200843D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0200844D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0300957D0 (sv) 2003-04-01 2003-04-01 Astrazeneca Ab Chemical compounds
TW200533348A (en) * 2004-02-18 2005-10-16 Theravance Inc Indazole-carboxamide compounds as 5-ht4 receptor agonists
US7728006B2 (en) * 2004-04-07 2010-06-01 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
US8309575B2 (en) 2004-04-07 2012-11-13 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
TWI351282B (en) 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
WO2006052640A1 (en) * 2004-11-05 2006-05-18 Theravance, Inc. 5-ht4 receptor agonist compounds
ES2327142T3 (es) * 2004-11-05 2009-10-26 Theravance, Inc. Compuestos de quinolinona-carboxamida.
NZ555180A (en) * 2004-12-22 2010-09-30 Theravance Inc Indazole-carboxamide compounds useful as 5-HT4 receptor agonists
NZ560828A (en) * 2005-03-02 2011-01-28 Theravance Inc Quinolinone compounds as 5-HT4 receptor agonists
MY147756A (en) 2005-05-25 2013-01-15 Theravance Inc Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists
US7256294B2 (en) * 2005-05-25 2007-08-14 Theravance, Inc. Crystalline form of a benzimidazole-carboxamide medicinal compound
TW200722419A (en) * 2005-05-27 2007-06-16 Astrazeneca Ab Chemical compounds
EP1888527A1 (en) * 2005-05-27 2008-02-20 AstraZeneca AB Piperidines for the treatment of chemokine mediated diseases
ES2397418T3 (es) 2005-07-21 2013-03-06 Astrazeneca Ab Derivados de piperidina
GB0525068D0 (en) 2005-12-08 2006-01-18 Novartis Ag Organic compounds
TWI423967B (zh) * 2008-02-21 2014-01-21 Dainippon Sumitomo Pharma Co 醯胺衍生物及含有其之醫藥組合物
US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
WO2011092293A2 (en) 2010-02-01 2011-08-04 Novartis Ag Cyclohexyl amide derivatives as crf receptor antagonists
US20120295942A1 (en) 2010-02-01 2012-11-22 Nicholas James Devereux Pyrazolo[5,1b]oxazole Derivatives as CRF-1 Receptor Antagonists
JP5748777B2 (ja) 2010-02-02 2015-07-15 ノバルティス アーゲー Ｃｒｆ受容体アンタゴニストとしてのシクロヘキシルアミド誘導体
US8546416B2 (en) 2011-05-27 2013-10-01 Novartis Ag 3-spirocyclic piperidine derivatives as ghrelin receptor agonists
JP2015525202A (ja) 2012-05-03 2015-09-03 ノバルティス アーゲー グレリン受容体アゴニストとしての２，７−ジアザ−スピロ［４，５］デカ−７−イル誘導体のｌ−リンゴ酸塩およびその結晶形態

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH111472A (ja) 1996-04-30 1999-01-06 Dainippon Pharmaceut Co Ltd ベンズアミド誘導体及びそれを含有する医薬組成物
KR20010043032A (ko) * 1998-04-28 2001-05-25 도모따께 다께시 1-[(1-치환-4-피페리디닐)메틸]-4-피페리딘 유도체, 그의제조방법, 그것을 함유하는의약조성물 및 이 화합물의중간체
JP2000080081A (ja) 1998-06-24 2000-03-21 Dainippon Pharmaceut Co Ltd １―〔（１―置換―４―ピペリジニル）メチル〕―４―ピペリジン誘導体及びそれを含有する医薬組成物
JP2001122784A (ja) 1999-10-27 2001-05-08 Dainippon Pharmaceut Co Ltd １−［（１−置換−４−ピペリジニル）メチル］−４−ピペリジン誘導体からなる医薬

Also Published As

Publication number Publication date
EP1362857A1 (en) 2003-11-19
SK50192004A3 (sk) 2005-04-01
DK1362857T3 (da) 2004-12-20
MXPA04011332A (es) 2005-02-14
IL165012A0 (en) 2005-12-18
US20030216433A1 (en) 2003-11-20
AR040021A1 (es) 2005-03-09
CZ20041084A3 (cs) 2005-02-16
CN1653063A (zh) 2005-08-10
AU2003230245A1 (en) 2003-12-02
HK1060118A1 (en) 2004-07-30
KR20040107520A (ko) 2004-12-20
DE60300021T2 (de) 2005-09-08
EP1362857B1 (en) 2004-08-11
NO20045469L (no) 2005-02-16
JP2004043453A (ja) 2004-02-12
CA2483368A1 (en) 2003-11-27
JP3643107B2 (ja) 2005-04-27
BR0309933A (pt) 2005-02-09
DE60300021D1 (de) 2004-09-16
PT1362857E (pt) 2004-11-30
ES2227500T3 (es) 2005-04-01
TW200400186A (en) 2004-01-01
PL372724A1 (en) 2005-07-25
WO2003097638A1 (en) 2003-11-27
RU2004136853A (ru) 2005-06-27
ZA200409053B (en) 2005-07-12
US6696468B2 (en) 2004-02-24
ATE273304T1 (de) 2004-08-15
TR200403020T2 (tr) 2005-05-23

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Legal Events

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