PT1362857E - (s)-4-amino-5-cloro-2-metoxi-n-[1-[1-(2-tetra-hidrofuril-carbonil)-4-piperidinilmetil[-4-piperidinil]-benzamida para o tratamento de disturbios da motilidade gastrintestinal - Google Patents

(s)-4-amino-5-cloro-2-metoxi-n-[1-[1-(2-tetra-hidrofuril-carbonil)-4-piperidinilmetil[-4-piperidinil]-benzamida para o tratamento de disturbios da motilidade gastrintestinal

Info

Publication number
PT1362857E
PT1362857E PT03250050T PT03250050T PT1362857E PT 1362857 E PT1362857 E PT 1362857E PT 03250050 T PT03250050 T PT 03250050T PT 03250050 T PT03250050 T PT 03250050T PT 1362857 E PT1362857 E PT 1362857E
Authority
PT
Portugal
Prior art keywords
gastrintestinal
piperidinylethyl
tetrahydrofuryl
motility
benzamide
Prior art date
Application number
PT03250050T
Other languages
English (en)
Inventor
Shiro Kato
Hiroshi Yamazaki
Yoshimi Hirokawa
Yoko Kan
Naoyuki Yoshida
Kazuo Morikage
Yukiko Morikage
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of PT1362857E publication Critical patent/PT1362857E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT03250050T 2002-05-16 2003-01-03 (s)-4-amino-5-cloro-2-metoxi-n-[1-[1-(2-tetra-hidrofuril-carbonil)-4-piperidinilmetil[-4-piperidinil]-benzamida para o tratamento de disturbios da motilidade gastrintestinal PT1362857E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002141262 2002-05-16

Publications (1)

Publication Number Publication Date
PT1362857E true PT1362857E (pt) 2004-11-30

Family

ID=29267809

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03250050T PT1362857E (pt) 2002-05-16 2003-01-03 (s)-4-amino-5-cloro-2-metoxi-n-[1-[1-(2-tetra-hidrofuril-carbonil)-4-piperidinilmetil[-4-piperidinil]-benzamida para o tratamento de disturbios da motilidade gastrintestinal

Country Status (27)

Country Link
US (1) US6696468B2 (pt)
EP (1) EP1362857B1 (pt)
JP (1) JP3643107B2 (pt)
KR (1) KR20040107520A (pt)
CN (1) CN1653063A (pt)
AR (1) AR040021A1 (pt)
AT (1) ATE273304T1 (pt)
AU (1) AU2003230245A1 (pt)
BR (1) BR0309933A (pt)
CA (1) CA2483368A1 (pt)
CZ (1) CZ20041084A3 (pt)
DE (1) DE60300021T2 (pt)
DK (1) DK1362857T3 (pt)
ES (1) ES2227500T3 (pt)
HK (1) HK1060118A1 (pt)
HU (1) HUP0501016A2 (pt)
IL (1) IL165012A0 (pt)
MX (1) MXPA04011332A (pt)
NO (1) NO20045469L (pt)
PL (1) PL372724A1 (pt)
PT (1) PT1362857E (pt)
RU (1) RU2004136853A (pt)
SK (1) SK50192004A3 (pt)
TR (1) TR200403020T2 (pt)
TW (1) TW200400186A (pt)
WO (1) WO2003097638A1 (pt)
ZA (1) ZA200409053B (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904377D0 (sv) * 1999-12-01 1999-12-01 Astra Pharma Prod Pharmaceutical combinations
SE0200844D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0200843D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0300957D0 (sv) 2003-04-01 2003-04-01 Astrazeneca Ab Chemical compounds
TW200533348A (en) * 2004-02-18 2005-10-16 Theravance Inc Indazole-carboxamide compounds as 5-ht4 receptor agonists
US8309575B2 (en) 2004-04-07 2012-11-13 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
TWI351282B (en) 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
US7728006B2 (en) * 2004-04-07 2010-06-01 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
WO2006052640A1 (en) * 2004-11-05 2006-05-18 Theravance, Inc. 5-ht4 receptor agonist compounds
EP1807423B1 (en) * 2004-11-05 2009-05-20 Theravance, Inc. Quinolinone-carboxamide compounds
BRPI0519708A2 (pt) * 2004-12-22 2009-03-10 Theravance Inc compostos de indazol-carboxamida
KR20070107807A (ko) * 2005-03-02 2007-11-07 세라밴스 인코포레이티드 5-ｈｔ4 수용체 아고니스트인 퀴놀리논 화합물
US7256294B2 (en) * 2005-05-25 2007-08-14 Theravance, Inc. Crystalline form of a benzimidazole-carboxamide medicinal compound
MY147756A (en) 2005-05-25 2013-01-15 Theravance Inc Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists
TW200722419A (en) * 2005-05-27 2007-06-16 Astrazeneca Ab Chemical compounds
WO2006126948A1 (en) * 2005-05-27 2006-11-30 Astrazeneca Ab Piperidines for the treatment of chemokine mediated diseases
BRPI0613563A2 (pt) 2005-07-21 2012-01-17 Astrazeneca Ab novos derivados de piperidina
GB0525068D0 (en) 2005-12-08 2006-01-18 Novartis Ag Organic compounds
TWI423967B (zh) * 2008-02-21 2014-01-21 Dainippon Sumitomo Pharma Co 醯胺衍生物及含有其之醫藥組合物
US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
AR080055A1 (es) 2010-02-01 2012-03-07 Novartis Ag Derivados de pirazolo-[5,1-b]-oxazol como antagonistas de los receptores de crf -1
WO2011092293A2 (en) 2010-02-01 2011-08-04 Novartis Ag Cyclohexyl amide derivatives as crf receptor antagonists
CN102753527B (zh) 2010-02-02 2014-12-24 诺华股份有限公司 用作crf受体拮抗剂的环己基酰胺衍生物
AR086554A1 (es) 2011-05-27 2014-01-08 Novartis Ag Derivados de la piperidina 3-espirociclica como agonistas de receptores de la ghrelina
EP2852591A1 (en) 2012-05-03 2015-04-01 Novartis AG L-malate salt of 2, 7 - diaza - spiro [4.5]dec- 7 - yle derivatives and crystalline forms thereof as ghrelin receptor agonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH111472A (ja) 1996-04-30 1999-01-06 Dainippon Pharmaceut Co Ltd ベンズアミド誘導体及びそれを含有する医薬組成物
RU2214400C2 (ru) * 1998-04-28 2003-10-20 Дайниппон Фармасьютикал Ко., Лтд. Производные 1-[(1-замещенного-4-пиперидинил)метил]-4-пиперидина, способы их получения, фармацевтическая композиция на их основе и промежуточные вещества
JP2000080081A (ja) 1998-06-24 2000-03-21 Dainippon Pharmaceut Co Ltd １―〔（１―置換―４―ピペリジニル）メチル〕―４―ピペリジン誘導体及びそれを含有する医薬組成物
JP2001122784A (ja) 1999-10-27 2001-05-08 Dainippon Pharmaceut Co Ltd １−［（１−置換−４−ピペリジニル）メチル］−４−ピペリジン誘導体からなる医薬

Also Published As

Publication number Publication date
SK50192004A3 (sk) 2005-04-01
ATE273304T1 (de) 2004-08-15
DE60300021T2 (de) 2005-09-08
ZA200409053B (en) 2005-07-12
TW200400186A (en) 2004-01-01
US20030216433A1 (en) 2003-11-20
CN1653063A (zh) 2005-08-10
ES2227500T3 (es) 2005-04-01
PL372724A1 (en) 2005-07-25
AR040021A1 (es) 2005-03-09
KR20040107520A (ko) 2004-12-20
US6696468B2 (en) 2004-02-24
RU2004136853A (ru) 2005-06-27
BR0309933A (pt) 2005-02-09
HUP0501016A2 (en) 2006-02-28
MXPA04011332A (es) 2005-02-14
CZ20041084A3 (cs) 2005-02-16
IL165012A0 (en) 2005-12-18
EP1362857A1 (en) 2003-11-19
WO2003097638A1 (en) 2003-11-27
HK1060118A1 (en) 2004-07-30
EP1362857B1 (en) 2004-08-11
AU2003230245A1 (en) 2003-12-02
NO20045469L (no) 2005-02-16
DE60300021D1 (de) 2004-09-16
TR200403020T2 (tr) 2005-05-23
DK1362857T3 (da) 2004-12-20
JP2004043453A (ja) 2004-02-12
JP3643107B2 (ja) 2005-04-27
CA2483368A1 (en) 2003-11-27

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