ZA200409053B - (S)-4-Amino-5-chloro-2-methoxy-N-[1-[1-(2-tetrahydrofuryl-carbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamin de, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor. - Google Patents

(S)-4-Amino-5-chloro-2-methoxy-N-[1-[1-(2-tetrahydrofuryl-carbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamin de, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor. Download PDF

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Publication number
ZA200409053B
ZA200409053B ZA200409035A ZA200409053A ZA200409053B ZA 200409053 B ZA200409053 B ZA 200409053B ZA 200409035 A ZA200409035 A ZA 200409035A ZA 200409053 A ZA200409053 A ZA 200409053A ZA 200409053 B ZA200409053 B ZA 200409053B
Authority
ZA
South Africa
Prior art keywords
compound
amino
pharmaceutically acceptable
addition salt
piperidinylmethyl
Prior art date
Application number
ZA200409035A
Other languages
English (en)
Inventor
Shiro Kato
Hiroshi Yamazaki
Yoshimi Hirokawa
Yoko Kan
Naoyuki Yoshida
Kazuo Morikage
Yukiko Morikage
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of ZA200409053B publication Critical patent/ZA200409053B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200409035A 2002-05-16 2004-11-09 (S)-4-Amino-5-chloro-2-methoxy-N-[1-[1-(2-tetrahydrofuryl-carbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamin de, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor. ZA200409053B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002141262 2002-05-16

Publications (1)

Publication Number Publication Date
ZA200409053B true ZA200409053B (en) 2005-07-12

Family

ID=29267809

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200409035A ZA200409053B (en) 2002-05-16 2004-11-09 (S)-4-Amino-5-chloro-2-methoxy-N-[1-[1-(2-tetrahydrofuryl-carbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamin de, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor.

Country Status (27)

Country Link
US (1) US6696468B2 (da)
EP (1) EP1362857B1 (da)
JP (1) JP3643107B2 (da)
KR (1) KR20040107520A (da)
CN (1) CN1653063A (da)
AR (1) AR040021A1 (da)
AT (1) ATE273304T1 (da)
AU (1) AU2003230245A1 (da)
BR (1) BR0309933A (da)
CA (1) CA2483368A1 (da)
CZ (1) CZ20041084A3 (da)
DE (1) DE60300021T2 (da)
DK (1) DK1362857T3 (da)
ES (1) ES2227500T3 (da)
HK (1) HK1060118A1 (da)
HU (1) HUP0501016A2 (da)
IL (1) IL165012A0 (da)
MX (1) MXPA04011332A (da)
NO (1) NO20045469L (da)
PL (1) PL372724A1 (da)
PT (1) PT1362857E (da)
RU (1) RU2004136853A (da)
SK (1) SK50192004A3 (da)
TR (1) TR200403020T2 (da)
TW (1) TW200400186A (da)
WO (1) WO2003097638A1 (da)
ZA (1) ZA200409053B (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904377D0 (sv) * 1999-12-01 1999-12-01 Astra Pharma Prod Pharmaceutical combinations
SE0200844D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0200843D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0300957D0 (sv) 2003-04-01 2003-04-01 Astrazeneca Ab Chemical compounds
TW200533348A (en) * 2004-02-18 2005-10-16 Theravance Inc Indazole-carboxamide compounds as 5-ht4 receptor agonists
US8309575B2 (en) 2004-04-07 2012-11-13 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
TWI351282B (en) * 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
US7728006B2 (en) * 2004-04-07 2010-06-01 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
DE602005014566D1 (de) * 2004-11-05 2009-07-02 Theravance Inc Chinolinon-carboxamid-verbindungen
DE602005016446D1 (de) * 2004-11-05 2009-10-15 Theravance Inc 5-HT4-Rezeptoragonistenverbindungen
CA2588037A1 (en) * 2004-12-22 2006-06-29 Theravance, Inc. Indazole-carboxamide compounds
NZ560828A (en) * 2005-03-02 2011-01-28 Theravance Inc Quinolinone compounds as 5-HT4 receptor agonists
MY147756A (en) 2005-05-25 2013-01-15 Theravance Inc Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists
US7256294B2 (en) * 2005-05-25 2007-08-14 Theravance, Inc. Crystalline form of a benzimidazole-carboxamide medicinal compound
EP1888527A1 (en) * 2005-05-27 2008-02-20 AstraZeneca AB Piperidines for the treatment of chemokine mediated diseases
TW200722419A (en) * 2005-05-27 2007-06-16 Astrazeneca Ab Chemical compounds
RU2008105987A (ru) 2005-07-21 2009-08-27 Астразенека Аб (Se) Новые пиперидиновые производные
GB0525068D0 (en) 2005-12-08 2006-01-18 Novartis Ag Organic compounds
TWI423967B (zh) * 2008-02-21 2014-01-21 Dainippon Sumitomo Pharma Co 醯胺衍生物及含有其之醫藥組合物
US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
WO2011092293A2 (en) 2010-02-01 2011-08-04 Novartis Ag Cyclohexyl amide derivatives as crf receptor antagonists
JP2013518085A (ja) 2010-02-01 2013-05-20 ノバルティス アーゲー CRF−1受容体アンタゴニストとしてのピラゾロ[5,1b]オキサゾール誘導体
WO2011095450A1 (en) 2010-02-02 2011-08-11 Novartis Ag Cyclohexyl amide derivatives as crf receptor antagonists
UY34094A (es) 2011-05-27 2013-01-03 Novartis Ag Derivados de la piperidina 3-espirocíclica como agonistas de receptores de la ghrelina
AU2013255458A1 (en) 2012-05-03 2014-10-09 Novartis Ag L-malate salt of 2, 7 - diaza - spiro [4.5 ] dec- 7 - yle derivatives and crystalline forms thereof as ghrelin receptor agonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH111472A (ja) 1996-04-30 1999-01-06 Dainippon Pharmaceut Co Ltd ベンズアミド誘導体及びそれを含有する医薬組成物
EP1076055B1 (en) * 1998-04-28 2004-11-24 Dainippon Pharmaceutical Co., Ltd. 1- (1-substituted-4-piperidinyl)methyl]-4-piperidine derivatives, process for producing the same, medicinal compositions containing the same and intermediates of these compounds
JP2000080081A (ja) 1998-06-24 2000-03-21 Dainippon Pharmaceut Co Ltd 1―〔(1―置換―4―ピペリジニル)メチル〕―4―ピペリジン誘導体及びそれを含有する医薬組成物
JP2001122784A (ja) 1999-10-27 2001-05-08 Dainippon Pharmaceut Co Ltd 1−[(1−置換−4−ピペリジニル)メチル]−4−ピペリジン誘導体からなる医薬

Also Published As

Publication number Publication date
TR200403020T2 (tr) 2005-05-23
AR040021A1 (es) 2005-03-09
US6696468B2 (en) 2004-02-24
ATE273304T1 (de) 2004-08-15
US20030216433A1 (en) 2003-11-20
DK1362857T3 (da) 2004-12-20
JP3643107B2 (ja) 2005-04-27
NO20045469L (no) 2005-02-16
KR20040107520A (ko) 2004-12-20
IL165012A0 (en) 2005-12-18
HK1060118A1 (en) 2004-07-30
EP1362857A1 (en) 2003-11-19
DE60300021T2 (de) 2005-09-08
DE60300021D1 (de) 2004-09-16
MXPA04011332A (es) 2005-02-14
RU2004136853A (ru) 2005-06-27
WO2003097638A1 (en) 2003-11-27
CZ20041084A3 (cs) 2005-02-16
EP1362857B1 (en) 2004-08-11
SK50192004A3 (sk) 2005-04-01
CN1653063A (zh) 2005-08-10
AU2003230245A1 (en) 2003-12-02
HUP0501016A2 (en) 2006-02-28
PL372724A1 (en) 2005-07-25
BR0309933A (pt) 2005-02-09
JP2004043453A (ja) 2004-02-12
ES2227500T3 (es) 2005-04-01
TW200400186A (en) 2004-01-01
PT1362857E (pt) 2004-11-30
CA2483368A1 (en) 2003-11-27

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