ID28696A - Penggunaan medis suatu modulator reseptor estrogen selektif dalam kombinasi dengan prekursor-prekursor steroid kelamin - Google Patents

Penggunaan medis suatu modulator reseptor estrogen selektif dalam kombinasi dengan prekursor-prekursor steroid kelamin

Info

Publication number
ID28696A
ID28696A IDW20010032A ID20010032A ID28696A ID 28696 A ID28696 A ID 28696A ID W20010032 A IDW20010032 A ID W20010032A ID 20010032 A ID20010032 A ID 20010032A ID 28696 A ID28696 A ID 28696A
Authority
ID
Indonesia
Prior art keywords
estrogent
gold
selective
combination
medical use
Prior art date
Application number
IDW20010032A
Other languages
English (en)
Indonesian (id)
Inventor
Fernand Labrie
Original Assignee
Endorech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endorech Inc filed Critical Endorech Inc
Publication of ID28696A publication Critical patent/ID28696A/id

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26Androgens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IDW20010032A 1998-06-11 1999-06-10 Penggunaan medis suatu modulator reseptor estrogen selektif dalam kombinasi dengan prekursor-prekursor steroid kelamin ID28696A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/096,284 US6465445B1 (en) 1998-06-11 1998-06-11 Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors

Publications (1)

Publication Number Publication Date
ID28696A true ID28696A (id) 2001-06-28

Family

ID=22256661

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20010032A ID28696A (id) 1998-06-11 1999-06-10 Penggunaan medis suatu modulator reseptor estrogen selektif dalam kombinasi dengan prekursor-prekursor steroid kelamin

Country Status (29)

Country Link
US (6) US6465445B1 (pt)
EP (5) EP2386305B9 (pt)
JP (3) JP2002517433A (pt)
KR (6) KR20090018227A (pt)
CN (2) CN1636566A (pt)
AR (1) AR043075A1 (pt)
AT (1) ATE308326T1 (pt)
AU (1) AU4253099A (pt)
BR (1) BR9911116A (pt)
CA (7) CA2768682C (pt)
CY (4) CY1113712T1 (pt)
DE (1) DE69928104T2 (pt)
DK (5) DK2386304T3 (pt)
ES (5) ES2253922T3 (pt)
HK (1) HK1040367B (pt)
HU (2) HU230495B1 (pt)
ID (1) ID28696A (pt)
IL (3) IL140178A0 (pt)
MX (1) MXPA00012306A (pt)
MY (3) MY151187A (pt)
NO (2) NO331022B1 (pt)
NZ (1) NZ508801A (pt)
PL (4) PL203343B1 (pt)
PT (4) PT2386304E (pt)
RU (1) RU2246947C2 (pt)
TR (5) TR200100551T2 (pt)
TW (2) TWI371279B (pt)
WO (1) WO1999063974A2 (pt)
ZA (1) ZA200007297B (pt)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2234060A1 (en) * 1995-10-06 1997-04-10 Arch Development Corporation Methods and compositions for viral enhancement of cell killing
US7005428B1 (en) * 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US6465445B1 (en) * 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
EP1104414B1 (en) * 1998-08-14 2003-02-12 Schering Corporation Enantioselective synthesis
US20030060425A1 (en) * 1998-11-24 2003-03-27 Ahlem Clarence N. Immune modulation method using steroid compounds
WO2000037083A1 (en) * 1998-12-18 2000-06-29 Schering Corporation Oral antiestrogen pharmaceutical composition
CA2376797C (en) 1999-06-11 2011-03-22 Watson Pharmaceuticals, Inc. Administration of non oral androgenic steroids to women
TR200403328T2 (tr) 1999-07-06 2005-03-21 Endorecherche, Inc. Kilo alımını tedavi ve/veya önleme metotları.
AU7896100A (en) * 1999-10-14 2001-04-23 Endorecherche Inc. Selective estrogen receptor modulators in the treatment or reduction of the riskof acquiring hypertension, cardiovascular diseases, and insulin resistance
TW593256B (en) * 1999-11-16 2004-06-21 Hormos Medical Oy Ltd Triphenylalkene derivatives and their use as selective estrogen receptor modulators
WO2001054699A1 (en) * 2000-01-28 2001-08-02 Endorecherche, Inc. Selective estrogen receptor modulators in combination with estrogens
US7241753B2 (en) 2000-02-25 2007-07-10 Loria Roger M Method of treatment of prostate cancer
EP1282615B1 (en) * 2000-03-01 2011-10-19 N.V. Organon Chroman derivatives as estrogenic compounds
JP2004502730A (ja) * 2000-07-06 2004-01-29 ワイス ビスホスホネート、エストロゲン剤および所望によるエストロゲンの組み合わせ
JP2004502734A (ja) * 2000-07-06 2004-01-29 ワイス 一酸化窒素シンターゼ活性の増強方法
AU2001273144A1 (en) * 2000-07-06 2002-01-21 Wyeth Use of substituted indole compounds for treating neuropeptide y-related conditions
ES2228932T3 (es) 2000-08-11 2005-04-16 Wyeth Procedimiento de tratamiento del carcinoma positivo de estrogenos.
EP1192945A3 (en) * 2000-09-21 2004-03-03 Pfizer Products Inc. Use of an estrogen agonist/antagonist for treating osteoarthritis
TWI303990B (en) * 2000-10-17 2008-12-11 Pfizer Prod Inc New use of estrogen agonists/antagonists for improving vascular health
AU781168B2 (en) * 2001-01-26 2005-05-12 Pfizer Products Inc. Method of treating certain cancers using an estrogen agonist/antagonist
FR2827764B1 (fr) * 2001-07-27 2005-08-19 Oreal Composition, notamment cosmetique, renfermant un steroide et un glycol
EP1411922A1 (en) 2001-07-31 2004-04-28 Pfizer Products Inc. Pharmaceutical compositions, kits and methods comprising combinations of estrogen agonists/antagonists, estrogens and progestins
US20040044226A1 (en) * 2001-10-15 2004-03-04 Dininno Frank P. Estrogen receptor modulators
JP4554219B2 (ja) * 2002-04-24 2010-09-29 メルク・シャープ・エンド・ドーム・コーポレイション エストロゲン受容体調節剤
US20040248989A1 (en) 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
CA2536946A1 (en) * 2003-08-26 2005-03-03 Board Of Regents, The University Of Texas System Estrogen receptor modulators and uses thereof
US8080675B2 (en) 2004-09-21 2011-12-20 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
EP2407462B1 (en) 2004-09-21 2014-07-30 Marshall Edwards, Inc. Substituted chroman derivatives, medicaments and use in therapy
US8941594B2 (en) * 2004-10-01 2015-01-27 Nvidia Corporation Interface, circuit and method for interfacing with an electronic device
CN106038572A (zh) * 2004-10-20 2016-10-26 恩多研究公司 性甾体前体单独或与选择性雌激素受体调节剂联合用于预防和治疗绝经后女性的性功能障碍
DK1871433T3 (da) 2005-03-24 2009-08-10 Nolabs Ab Kosmetisk behandling med nitrogenoxid, anordning til udförelse af denne behandling samt fremstillingsproces dertil
WO2007135547A2 (en) 2006-05-22 2007-11-29 Hormos Medical Ltd. Selective estrogen receptor modulators or aromatase inhibitors for treating chronic nonbacterial prostatitis
KR20090029237A (ko) 2006-06-02 2009-03-20 피어 트리 파머슈티칼스 인코포레이티드 위축성 질염을 치료하는 방법
US7504530B2 (en) 2007-02-14 2009-03-17 Hormos Medical Ltd. Methods for the preparation of fispemifene from ospemifene
ES2590262T3 (es) 2007-02-14 2016-11-21 Hormos Medical Ltd. Método para la preparación de derivados de trifenilbuteno con valor terapéutico
US8268806B2 (en) * 2007-08-10 2012-09-18 Endorecherche, Inc. Pharmaceutical compositions
AU2012204083C1 (en) * 2007-08-10 2015-02-05 Myriel Pharmaceuticals, Llc DHEA compositions for treating menopause
US20100048913A1 (en) 2008-03-14 2010-02-25 Angela Brodie Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity
US20100075937A1 (en) * 2008-09-24 2010-03-25 Hollis-Eden Pharmaceuticals, Inc. Patient populations and treatment methods
US20110312916A1 (en) 2009-02-05 2011-12-22 Tokai Pharmaceuticals, Inc. Novel prodrugs of steroidal cyp17 inhibitors/antiandrogens
US20120142645A1 (en) * 2009-03-17 2012-06-07 Marx Christine E Neuroactive steroid compositions and methods of use for lowering cholesterol
US20100317635A1 (en) 2009-06-16 2010-12-16 Endorecherche, Inc. Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators
AU2014201406B2 (en) * 2009-06-16 2016-08-11 Endorecherche, Inc. Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators
ES2627692T3 (es) * 2010-06-10 2017-07-31 Aragon Pharmaceuticals, Inc. Moduladores de receptores de estrógenos y usos de los mismos
KR20150039882A (ko) * 2010-06-16 2015-04-13 앙도르쉐르슈 인코포레이티드 에스트로겐-관련 질병의 치료 또는 예방 방법
CA2816319C (en) 2010-11-01 2020-06-30 Marshall Edwards, Inc. Isoflavonoid compounds and methods for the treatment of cancer
JP6277124B2 (ja) * 2011-07-05 2018-02-07 ノヴァン,インコーポレイテッド 局所用組成物
WO2013006613A1 (en) 2011-07-05 2013-01-10 Novan, Inc. Methods of manufacturing topical compositions and apparatus for same
WO2013012326A1 (en) * 2011-07-19 2013-01-24 Pantarhei Bioscience B.V. Tablet containing dehydroepiandrosterone (dhea)
US9320744B2 (en) 2011-10-19 2016-04-26 Dhea Llc DHEA bioadhesive controlled release gel
CA2856520C (en) 2011-11-23 2021-04-06 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
CA2857057A1 (en) 2011-12-14 2013-06-20 Seragon Pharmaceuticals, Inc. Fluorinated estrogen receptor modulators and uses thereof
CA2857061A1 (en) 2011-12-16 2013-06-20 Olema Pharmaceuticals, Inc. Novel benzopyran compounds, compositions and uses thereof
CN102631677A (zh) * 2012-04-19 2012-08-15 中国农业大学 一种预防和/或治疗动脉粥样硬化的药物组合物
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
WO2014060639A1 (en) 2012-10-19 2014-04-24 Fermion Oy A process for the preparation of ospemifene
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9855211B2 (en) 2013-02-28 2018-01-02 Novan, Inc. Topical compositions and methods of using the same
US9884067B2 (en) 2013-03-14 2018-02-06 University Of Maryland, Baltimore Androgen receptor down-regulating agents and uses thereof
WO2014203129A1 (en) 2013-06-19 2014-12-24 Olema Pharmaceuticals, Inc. Combinations of benzopyran compounds, compositions and uses thereof
WO2014203132A1 (en) 2013-06-19 2014-12-24 Olema Pharmaceuticals, Inc. Substituted benzopyran compounds, compositions and uses thereof
CN105979969B (zh) 2013-08-08 2020-09-11 诺万公司 局部用组合物和使用所述组合物的方法
US10206947B2 (en) 2013-08-08 2019-02-19 Novan, Inc. Topical compositions and methods of using the same
WO2015023710A1 (en) 2013-08-12 2015-02-19 Tokai Pharmaceuticals, Inc. Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies
US9744177B2 (en) * 2014-03-10 2017-08-29 Endorecherche, Inc. Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with SERM
AU2015264003A1 (en) 2014-05-22 2016-11-17 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP3698775A1 (en) 2014-07-11 2020-08-26 Novan Inc. Topical antiviral compositions and methods of using the same
US10322082B2 (en) 2014-07-11 2019-06-18 Novan, Inc. Topical antiviral compositions and methods of using the same
KR20170040209A (ko) 2014-07-29 2017-04-12 쎄러퓨틱스엠디, 인코퍼레이티드 경피 크림
GB201416186D0 (en) * 2014-09-12 2014-10-29 Redx Pharma Ltd Compounds
PT3253208T (pt) 2015-02-02 2021-06-17 The Spanish National Cancer Res Centre Terapêuticas de combinação para utilização no tratamento do cancro da mama
US10452661B2 (en) * 2015-06-18 2019-10-22 Microsoft Technology Licensing, Llc Automated database schema annotation
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10912743B2 (en) 2016-03-02 2021-02-09 Novan, Inc. Compositions for treating inflammation and methods of treating the same
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
CA3020153A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
WO2017180822A1 (en) 2016-04-13 2017-10-19 Novan, Inc. Compositions, systems, kits, and methods for treating an infection
FR3052805B1 (fr) 2016-06-20 2020-06-26 Safran Aircraft Engines Disque aubage monobloc ameliore, partie tournante d'une turbomachine comprenant un tel disque et turbomachine associee
CN109224029A (zh) * 2018-09-30 2019-01-18 泓博元生命科技(深圳)有限公司 含有nmn的降血脂组合物、制剂及其制备方法与应用
WO2021067600A1 (en) * 2019-10-03 2021-04-08 Caren Pharmaceuticals, Inc. Combination hormone formulations and therapies
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
AU2021314955A1 (en) 2020-07-28 2023-03-30 Jazz Pharmaceuticals Ireland Limited Fused bicyclic Raf inhibitors and methods for use thereof
WO2023156803A1 (en) * 2022-02-17 2023-08-24 Debreceni Egyetem Dhea-derived steroids
CN115554403B (zh) * 2022-08-16 2024-03-08 山东大学 类固醇激素dhea作为受体adgrg2激动剂配体的应用

Family Cites Families (106)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US536220A (en) * 1895-03-26 Puzzle
US550107A (en) * 1895-11-19 Thirds to henry zervas and julius wegert
DK122125B (da) 1967-10-04 1972-01-24 Schering Ag Analogifremgangsmåde til fremstilling af terapeutisk aktive carboxylsyreestere af 3β-hydroxy-5-androstan-17-on(dehydroepiandrosteron) med 7-11 carbonatomer i esterresten.
US3797494A (en) 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US3797444A (en) 1971-04-19 1974-03-19 H Stubbs Towing guide
US3742951A (en) 1971-08-09 1973-07-03 Alza Corp Bandage for controlled release of vasodilators
US4005200A (en) * 1975-07-17 1977-01-25 Kanebo, Ltd. Method for improving the maturity of the parturient canal and the sensitivity to oxytocin
US4496556A (en) 1982-08-16 1985-01-29 Norman Orentreich Topical applications for preventing dry skin
US4542129A (en) 1982-08-16 1985-09-17 Norman Orentreich DHEA Formulations and methods for treating dry skin
DE3333240A1 (de) 1983-09-12 1985-03-28 Schering AG, 1000 Berlin und 4709 Bergkamen Mittel zur transdermalen applikation von arzneimittelwirkstoffen
US4725439A (en) 1984-06-29 1988-02-16 Alza Corporation Transdermal drug delivery device
ATE75947T1 (de) 1984-08-02 1992-05-15 Labrie Fernand Pharmazeutische zusammensetzung fuer die kombinationstherapie von hormonabhaengigem krebs.
US4624665A (en) 1984-10-01 1986-11-25 Biotek, Inc. Method of transdermal drug delivery
US4568343A (en) 1984-10-09 1986-02-04 Alza Corporation Skin permeation enhancer compositions
US4666441A (en) 1985-12-17 1987-05-19 Ciba-Geigy Corporation Multicompartmentalized transdermal patches
IE60941B1 (en) 1986-07-10 1994-09-07 Elan Transdermal Ltd Transdermal drug delivery device
US4816258A (en) 1987-02-26 1989-03-28 Alza Corporation Transdermal contraceptive formulations
JP2551590B2 (ja) * 1987-06-26 1996-11-06 株式会社リコー 複写機光学系の速度制御方法
JPS6440428A (en) 1987-08-07 1989-02-10 Daiichi Yakuhin Sangyo Kk Antihyperlipemia
US5064654A (en) 1989-01-11 1991-11-12 Ciba-Geigy Corporation Mixed solvent mutually enhanced transdermal therapeutic system
US5162037A (en) 1988-04-01 1992-11-10 Whitson Laboratories, Inc. Magnetically influenced homeopathic pharmaceutical formulations, methods of their preparation and methods of their administration
US5393785A (en) 1988-10-31 1995-02-28 Endorecherche, Inc. Therapeutic antiestrogens
US5395842A (en) 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
US5686465A (en) 1988-10-31 1997-11-11 Endorecherche Inc. Sex steroid activity inhibitors
HU208150B (en) 1988-10-31 1993-08-30 Endorecherche Inc Process for producing new estrogen derivatives having steroid hormone inhibitor activity and pharmaceutical compositions comprising such derivatives
KR900701242A (ko) 1988-12-01 1990-12-01 스타이너 브이. 캔스타드 에스트라디올의 경피전달용 조성물
US4920115A (en) * 1988-12-28 1990-04-24 Virginia Commonwealth University Method of lowering LDL cholesterol in blood
DE69022722T2 (de) 1989-03-10 1996-05-02 Endorecherche Inc Kombinationstherapie zur behandlung von estrogenempfindlichen erkrankungen.
US5071644A (en) 1990-08-07 1991-12-10 Mediventures, Inc. Topical drug delivery with thermo-irreversible gels
HU222501B1 (hu) 1991-06-28 2003-07-28 Endorecherche Inc. MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
ZA924811B (en) 1991-06-28 1993-12-29 Endorecherche Inc Controlled release systems and low dose androgens
US6060503A (en) * 1991-12-02 2000-05-09 Endorecherche, Inc. Benzopyran-containing compounds and method for their use
TW366342B (en) 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
HUT64815A (en) 1992-09-04 1994-03-28 Berki An external correcting and fixing apparatus for treatment of fractures and defomities of bones as well as correcting unit preferably for external correcting and fixing units
US5354861A (en) 1992-11-04 1994-10-11 National University Of Singapore 2-(benzyl)-3-arylbenzofurans as antitumour and hypocholesterolemic agents
TW383306B (en) * 1992-12-22 2000-03-01 Lilly Co Eli New use of 2-phenyl-3-aroylbenzothiophenes in lowering serum cholesterol
US5776923A (en) 1993-01-19 1998-07-07 Endorecherche, Inc. Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone
ATE275957T1 (de) 1993-01-19 2004-10-15 Endorech Inc Therapeutische verwendungen und verabreichungsysteme von dehydroepiandrosteron
DE4401554A1 (de) 1993-02-16 1994-08-18 Freund Andreas Präparat zur Therapie und Prophylaxe von Erkrankungen, die bei Imbalancen von Plasmalipiden auftreten
ZA944377B (en) 1993-06-24 1995-12-20 Lilly Co Eli Hypoglycemic agents
US5441964A (en) 1993-10-15 1995-08-15 Eli Lilly And Company Methods for inhibiting bone loss using substituted benzothiophene
US5418252A (en) 1993-10-15 1995-05-23 Eli Lilly And Company Method for inhibiting cartilage degradation
US5482950A (en) 1993-10-15 1996-01-09 Eli Lilly And Company Methods for lowering serum cholesterol
US5391557A (en) 1993-10-15 1995-02-21 Eli Lilly And Company Methods for the treatment of peri-menopausal syndrome
US5407947A (en) * 1993-11-05 1995-04-18 Eli Lilly And Company Methods for inhibiting bone loss using pyrolidine and piperidine substituted benzopyrans
US5446061A (en) 1993-11-05 1995-08-29 Eli Lilly And Company Methods for lowering serum cholesterol
PT654267E (pt) * 1993-11-19 2002-09-30 Jenapharm Gmbh Carcinoestaticos para terapia hormonal contendo dienogest como componente eficaz
US5389646A (en) 1993-12-30 1995-02-14 Zymogenetics, Inc. Methods for treatment and prevention of bone loss using 2,3-benzopyrans
US5591753A (en) 1994-01-28 1997-01-07 Eli Lilly And Company Combination treatment for osteoporosis
US5478847A (en) 1994-03-02 1995-12-26 Eli Lilly And Company Methods of use for inhibiting bone loss and lowering serum cholesterol
US5425429A (en) * 1994-06-16 1995-06-20 Thompson; Michael C. Method and apparatus for forming lateral boreholes
US5681308A (en) 1994-06-24 1997-10-28 Stuart D. Edwards Ablation apparatus for cardiac chambers
UA41909C2 (uk) 1994-07-22 2001-10-15 Елі Ліллі Енд Компані Використання комбінації сполук для інгібірування остеопорозу, фармацевтичний препарат
CZ51897A3 (en) 1994-08-22 1997-06-11 Lilly Co Eli Inhibition method of endometrial cancer
US5550123A (en) 1994-08-22 1996-08-27 Eli Lilly And Company Methods for inhibiting bone prosthesis degeneration
US5502074A (en) 1994-08-22 1996-03-26 Eli Lilly And Company Benzothiophenes for bone healing and fracture repair
EP0769946A4 (en) 1994-08-22 1997-11-05 Lilly Co Eli METHOD FOR MAINTAINING THE TEETH AND BONE IN THE ORAL AREA
GB9418067D0 (en) 1994-09-07 1994-10-26 Orion Yhtymae Oy Triphenylethylenes for the prevention and treatment of osteoporosis
US6703407B1 (en) 1994-09-20 2004-03-09 Eli Lilly And Company Benzofuran compounds, compositions, and methods
US5484798A (en) 1994-09-20 1996-01-16 Eli Lilly And Company Benzothiopene compounds, compositions, and method of inhibiting restenosis
US5446071A (en) * 1994-11-18 1995-08-29 Eli Lilly And Company Methods for lowering serum cholesterol
US5637598A (en) 1994-11-18 1997-06-10 Eli Lilly And Company Methods of inhibiting bone loss
JPH10509962A (ja) 1994-11-29 1998-09-29 ヘキスト・マリオン・ルセル・インコーポレイテツド 骨粗鬆症の治療および予防におけるトリアリール−エチレン誘導体の使用方法
EP0804189A1 (en) * 1995-01-13 1997-11-05 Novo Nordisk A/S Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of hyperlipoproteinaemia, hypertriglyceridaemia, hyperlipidaemia or hypercholesterolaemia or arteriosclerosis or for anticoagulative treatment
US5489587A (en) 1995-01-20 1996-02-06 Eli Lilly And Company Benzofurans used to inhibit bone loss
US5571808A (en) 1995-01-31 1996-11-05 Eli Lilly And Company Method for treating smoking-related bone loss
US5552401A (en) 1995-02-28 1996-09-03 Eli Lilly And Company 2-benzyl-3-arylbenzothiophenes
US5523309A (en) 1995-03-10 1996-06-04 Eli Lilly And Company Benzofuran pharmaceutical compounds
US5567828A (en) 1995-06-07 1996-10-22 Eli Lilly And Company Compounds and compositions with nitrogen-containing non-basic side
DE69600709T2 (de) 1995-06-07 1999-03-18 Lilly Co Eli Verbindungen mit N-Acyliertem Piperidin in der Seitenkette und Zusammensetzungen
US5883118A (en) 1996-01-11 1999-03-16 Nova Nordisk A/S Prostatic carcinoma
WO1997025035A1 (en) 1996-01-11 1997-07-17 Novo Nordisk A/S Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of menopausal symptoms
US5747059A (en) 1996-01-11 1998-05-05 Novo Nordisk A/S Atrophy of skin/mucous membrane
BR9706966A (pt) 1996-01-11 1999-05-04 Novo Nordisk As Utilização do enanciômero-l de um composto e processo para tratamento ou profilaxia de câncer da mama
US5726202A (en) 1996-01-11 1998-03-10 Novo Nordisk A/S Benign prostatic hypertrophy
PT880540E (pt) * 1996-02-14 2002-10-31 Aventis Pharma Inc 17-beta-ciclopropil-(amino/oxi)-4-azaesteroides como inibidores activos de 5-alfa-redutase e c17-c20-liase de testosterona
US6432982B1 (en) 1996-02-21 2002-08-13 Eli Lilly And Company Benzothiophenes, and formulations and methods using same
IL125863A (en) 1996-02-22 2000-10-31 Lilly Co Eli Benzothiophenes and formulations containing same
IL120262A (en) 1996-02-28 2001-01-28 Pfizer Droloxifene and derivatives thereof for use in increasing serum testosterone levels
WO1997032837A1 (fr) 1996-03-06 1997-09-12 Sumitomo Pharmaceuticals Co., Ltd. Derives estrogenes non steroidiens
EP0801066A1 (en) 1996-03-12 1997-10-15 Eli Lilly And Company Heterocyclic substituted benzothiophenes and pharmaceutical compositions
ATE311886T1 (de) * 1996-04-11 2005-12-15 Roger M Loria Verwendung einer zusammensetzung enthaltend 5- androsten-3beta,17alpha-diol
TW397821B (en) 1996-04-19 2000-07-11 American Home Produits Corp 3-[4-(2-phenyl-indole-1-ylmethyl)-phenyl]-acrylamides and 2-phenyl-1-[4-(amino-1-yl-alk-1-ynyl)-benzyl]-1H-indol-5-ol as well as pharmaceutical compositions of estrogenic agents thereof
PT802183E (pt) 1996-04-19 2002-03-28 American Home Prod Agentes estrogenicos
US5843984A (en) 1996-05-09 1998-12-01 Eli Lilly And Company Sulfated benzothiophene derivatives, methods of use and formulations containing same
GB9616700D0 (en) * 1996-08-09 1996-09-25 Carey Beverly J Hormone supplement
NZ333839A (en) * 1996-08-28 2001-06-29 Lilly Co Eli Amorphous benzothiophenes
US6511970B1 (en) * 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6069175A (en) * 1996-11-15 2000-05-30 Pfizer Inc. Estrogen agonist/antagonists treatment of atherosclerosis
US5855920A (en) * 1996-12-13 1999-01-05 Chein; Edmund Y. M. Total hormone replacement therapy
US5861391A (en) * 1997-01-29 1999-01-19 Research Development Foundation Use of dehydroepiandrosterone to treat primary adrenal insufficiency and Addison's disease
CA2280033A1 (en) * 1997-02-07 1998-08-13 Susan Rako Composition and method for supplementing testosterone in women with symptoms of testosterone deficiency
GB9708716D0 (en) * 1997-04-29 1997-06-18 Imperial College Chronic heart failure
UA53716C2 (uk) 1997-06-25 2003-02-17 Пфайзер Продактс Інк. Тартратна сіль заміщеного дипептиду, спосіб її одержання, проміжні сполуки та спосіб їх одержання, фармацевтична композиція (варіанти), спосіб підвищення рівнів ендогенного гормону росту та спосіб лікування або профілактики захворювань (варіанти)
CO4940467A1 (es) * 1997-06-27 2000-07-24 Smithkline Beecham Corp Nuevos metodos
US5908859A (en) * 1997-08-11 1999-06-01 Eli Lilly And Company Benzothiophenes for inhibiting hyperlipidemia
JP2001520999A (ja) * 1997-10-28 2001-11-06 アシビ, エルエルシー 女性の性的機能不全の処置
CZ299334B6 (cs) 1998-05-15 2008-06-25 Wyeth Farmaceutický prostredek
NZ536787A (en) * 1998-06-11 2006-03-31 Endorech Inc Pharmaceutical compositions and uses for androst-5-ene-3beta,17beta diol
US6465445B1 (en) * 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US7005428B1 (en) * 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
HUP9900284A2 (hu) 1999-02-09 2001-02-28 János Váradi Háromfázisú, hidraulikus rugózó elem közúti és vasúti járművek számára
TR200403328T2 (tr) 1999-07-06 2005-03-21 Endorecherche, Inc. Kilo alımını tedavi ve/veya önleme metotları.
AU7896100A (en) * 1999-10-14 2001-04-23 Endorecherche Inc. Selective estrogen receptor modulators in the treatment or reduction of the riskof acquiring hypertension, cardiovascular diseases, and insulin resistance
CN106038572A (zh) * 2004-10-20 2016-10-26 恩多研究公司 性甾体前体单独或与选择性雌激素受体调节剂联合用于预防和治疗绝经后女性的性功能障碍
US8268806B2 (en) * 2007-08-10 2012-09-18 Endorecherche, Inc. Pharmaceutical compositions

Also Published As

Publication number Publication date
KR20090018871A (ko) 2009-02-23
PL203343B1 (pl) 2009-09-30
HUP0103345A2 (hu) 2002-02-28
CY1113712T1 (el) 2016-06-22
EP1623712A2 (en) 2006-02-08
EP2386305A3 (en) 2011-12-07
PL203704B1 (pl) 2009-11-30
JP2013049703A (ja) 2013-03-14
US8188066B2 (en) 2012-05-29
HK1040367B (zh) 2006-09-29
DE69928104D1 (de) 2005-12-08
ZA200007297B (en) 2002-02-08
MXPA00012306A (es) 2003-07-28
DK2386304T3 (da) 2014-05-12
HU230495B1 (hu) 2016-09-28
CY1115069T1 (el) 2016-12-14
TW200810763A (en) 2008-03-01
US20070027124A1 (en) 2007-02-01
BR9911116A (pt) 2001-02-28
TR200103456T2 (tr) 2002-06-21
CA2768773C (en) 2013-08-13
CA2334577A1 (en) 1999-12-16
TR200103455T2 (tr) 2002-06-21
DK1083905T3 (da) 2006-03-20
EP2386304B9 (en) 2014-11-05
PT2386304E (pt) 2014-05-26
NO332187B1 (no) 2012-07-23
KR20090018226A (ko) 2009-02-19
PT2399582E (pt) 2014-06-25
NO331022B1 (no) 2011-09-12
CA2768682C (en) 2014-03-18
EP1623712A3 (en) 2009-12-16
KR20090018227A (ko) 2009-02-19
CY1115317T1 (el) 2017-01-04
AU4253099A (en) 1999-12-30
KR20090016771A (ko) 2009-02-17
IL140178A0 (en) 2002-02-10
CA2768828A1 (en) 1999-12-16
US7943603B2 (en) 2011-05-17
MY151187A (en) 2014-04-30
HK1040367A1 (en) 2002-06-07
HUP0103345A3 (en) 2002-11-28
CA2768841C (en) 2013-08-13
ES2458218T3 (es) 2014-04-30
CA2768773A1 (en) 1999-12-16
EP2386305A2 (en) 2011-11-16
EP2386305B9 (en) 2014-12-17
PL195772B1 (pl) 2007-10-31
ES2253922T3 (es) 2006-06-01
ES2463868T3 (es) 2014-05-29
NO20006254L (no) 2001-02-01
CN1312718A (zh) 2001-09-12
IL185087A0 (en) 2007-12-03
NO20006254D0 (no) 2000-12-08
EP1083905A2 (en) 2001-03-21
KR100944261B1 (ko) 2010-02-24
CA2768682A1 (en) 1999-12-16
EP2386304A3 (en) 2011-12-07
AR043075A1 (es) 2005-07-20
IL140178A (en) 2008-07-08
CA2334577C (en) 2008-08-05
DK2386305T3 (da) 2014-04-14
JP2002517433A (ja) 2002-06-18
TWI258369B (en) 2006-07-21
DK1623712T3 (da) 2013-01-21
US20070027122A1 (en) 2007-02-01
JP2007191484A (ja) 2007-08-02
NZ508801A (en) 2003-08-29
CA2768882C (en) 2015-01-27
EP2386305B1 (en) 2014-02-12
CY1115231T1 (el) 2017-01-04
ES2458218T9 (es) 2014-06-24
CA2632567C (en) 2012-04-10
PL345887A1 (en) 2002-01-14
CN1240388C (zh) 2006-02-08
EP1083905B1 (en) 2005-11-02
US6465445B1 (en) 2002-10-15
RU2246947C2 (ru) 2005-02-27
TR200103454T2 (tr) 2002-06-21
ES2399051T3 (es) 2013-03-25
US20040157812A1 (en) 2004-08-12
PT1623712E (pt) 2013-02-13
US7429576B2 (en) 2008-09-30
EP2399582B1 (en) 2014-03-26
US20070027123A1 (en) 2007-02-01
NO20092730L (no) 2001-02-01
EP1623712B1 (en) 2012-12-12
US6670346B1 (en) 2003-12-30
TR200103453T2 (tr) 2002-06-21
MY157030A (en) 2016-04-15
ATE308326T1 (de) 2005-11-15
EP2399582B9 (en) 2014-09-10
CN1636566A (zh) 2005-07-13
WO1999063974A2 (en) 1999-12-16
US7884092B2 (en) 2011-02-08
MY125047A (en) 2006-07-31
PL199798B1 (pl) 2008-10-31
ES2463868T9 (es) 2014-06-24
TWI371279B (en) 2012-09-01
CA2768841A1 (en) 1999-12-16
CA2768882A1 (en) 1999-12-16
TR200100551T2 (tr) 2001-07-23
HU1600307D0 (hu) 2002-02-28
DE69928104T2 (de) 2006-08-24
EP2386304B1 (en) 2014-03-19
ES2473040T3 (es) 2014-07-03
CA2768828C (en) 2013-08-13
DK2399582T3 (da) 2014-07-07
KR20090018870A (ko) 2009-02-23
WO1999063974A3 (en) 2000-06-29
EP2399582A1 (en) 2011-12-28
PT2386305E (pt) 2014-04-17
EP2386304A2 (en) 2011-11-16
CA2632567A1 (en) 1999-12-16
KR20010052763A (ko) 2001-06-25

Similar Documents

Publication Publication Date Title
ID28696A (id) Penggunaan medis suatu modulator reseptor estrogen selektif dalam kombinasi dengan prekursor-prekursor steroid kelamin
NO20023484L (no) Selektive östrogenreseptormodulatorer i kombinasjon med östrogener
HUP0204029A3 (en) Triphenylalkene derivatives and their use as selective estrogen receptor modulators
HK1043788A1 (zh) 四環黃體酮受體調節劑化合物及方法
CY2009015I1 (el) Φαρμακευτικος συνδυασμος αιθινυλεστραδιολης και δροπιρενονης για χρηση ως αντισυλληπτικο
IL154425A0 (en) Selective androgen receptor modulators and methods of use thereof
NO20020912L (no) Bicykliske androgen- og progesteronreseptorer- modulatorforbindelser og fremgangsmåter
DK0938368T3 (da) Integreret knoglecementblande- og dispenseringssystem
ATE304359T1 (de) Anti-östrogen- und progestin-enthaltende orale kontrazeptiva
HUP0103993A3 (en) Ecdysone receptors and methods for their use
MXPA01011294A (es) Compuestos moduladores de receptor de progesterona tetraciclicos y metodos.
DE29610683U1 (de) Toilettenpapier mit Befeuchtung und Toilettenpapierspender zur Abgabe desselben
GB9420036D0 (en) Flushing device of toilet
DE69908592D1 (de) Kontinuierliche Misch- und Zuführvorrichtung
TWI293247B (en) Pharmaceutical compositions of a selective estrogen receptor modulator in combination with sex steroid precursors (2)
DE29615834U1 (de) Doppel-Einhebel-Wannen-Füll und Brause-Armatur
DE29821160U1 (de) Toilettenspülungs-Aktivierungsvorrichtung
SI1235776T1 (sl) Trifenilalkenski derivati in njihova uporaba kot selektivni estrogenski receptorski modulatorji
BR9502979A (pt) Manta higiênica flexivel e descartável para assento em vasos sanitários
IT238335Y1 (it) Scopino igienico usa-e-getta
HU9800209V0 (en) Multilayer and reusable higienic water-closet seat
FR2774282B3 (fr) Urinaux a usage medical et paramedical concus et equipes pour une utilisation parfaitement hygienique
PL56385Y1 (en) Lavatory bowl flushing device
KR970049011U (ko) 일회용 변기 깔게
KR970039435U (ko) 변기용 세정수 공급장치 구조