HUT53128A - Process for producing hyaluronic acid metal complexes and pharmaceutical compositions comprising such active ingredient - Google Patents
Process for producing hyaluronic acid metal complexes and pharmaceutical compositions comprising such active ingredientInfo
- Publication number
- HUT53128A HUT53128A HU89891A HU89189A HUT53128A HU T53128 A HUT53128 A HU T53128A HU 89891 A HU89891 A HU 89891A HU 89189 A HU89189 A HU 89189A HU T53128 A HUT53128 A HU T53128A
- Authority
- HU
- Hungary
- Prior art keywords
- active ingredient
- pharmaceutical compositions
- hyaluronic acid
- metal complexes
- acid metal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/58—Metal complex; Coordination compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Priority Applications (42)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU89891A HU203372B (en) | 1989-02-24 | 1989-02-24 | Process for producing hyaluronic associates and pharmaceutical compositions and cosmetics comprising such active ingredient |
JP2503644A JP2571312B2 (ja) | 1989-02-24 | 1990-02-20 | ヒアルロン酸会合物を含む新規組成物及びそれを調製するための方法 |
CA002027596A CA2027596C (en) | 1989-02-24 | 1990-02-20 | Compositions containing hyaluronic acid complexes with zinc or cobalt |
ES90903397T ES2061016T3 (es) | 1989-02-24 | 1990-02-20 | Nuevas composiciones que contienen asociados de acido hialuronico y procedimiento para su preparacion. |
KR1019900702327A KR960015624B1 (ko) | 1989-02-24 | 1990-02-20 | 히알루론산 회합체를 함유하는 신규 조성물 및 그 제조방법 |
UA4895005A UA26324A (uk) | 1989-02-24 | 1990-02-20 | Спосіб одержаhhя біологічhо активhої композиції |
AT90903397T ATE98964T1 (de) | 1989-02-24 | 1990-02-20 | Zusammensetzungen welche komplexe von hyaluronsaeure enthalten und verfahren zu deren herstellung. |
AU51088/90A AU623232B2 (en) | 1989-02-24 | 1990-02-20 | Novel compositions containing hyaluronic acid associates and a process for preparing same |
EP90903397A EP0413016B1 (en) | 1989-02-24 | 1990-02-20 | Novel compositions containing hyaluronic acid associates and a process for preparing same |
UA94061636A UA39174C2 (uk) | 1989-02-24 | 1990-02-20 | Асоціати депротонованої гіалуронової кислоти, спосіб одержання асоціатів депротонованої гіалуронової кислоти, фармацевтична композиція та спосіб одержання фармацевтичної композиції |
PCT/HU1990/000013 WO1990010020A1 (en) | 1989-02-24 | 1990-02-20 | Novel compositions containing hyaluronic acid associates and a process for preparing same |
DK90903397.9T DK0413016T3 (da) | 1989-02-24 | 1990-02-20 | Hidtil ukendte kompositioner indeholdende hyaluronnsyreassociater og fremgangsmåde til fremstilling heraf |
SU904831382A RU2099350C1 (ru) | 1989-02-24 | 1990-02-20 | Ассоциаты депротонированной гиалуроновой кислоты, способ их получения, фармацевтическая композиция, содержащая ассоциаты депротонированной гиалуроновой кислоты, и способ ее получения |
DE69005394T DE69005394T2 (de) | 1989-02-24 | 1990-02-20 | Zusammensetzungen welche komplexe von hyaluronsäure enthalten und verfahren zu deren herstellung. |
CS90857A CZ281000B6 (cs) | 1989-02-24 | 1990-02-22 | Nové prostředky obsahující asociáty kyseliny hyaluronové a způsob jejich přípravy |
PT93237A PT93237B (pt) | 1989-02-24 | 1990-02-22 | Processo para a preparacao de novos sais complexos derivados de acido hialuronico desprotonizado e de metais de transicao do 4 periodo da tabela periodica e de composicoes farmaceuticas e/ou cosmeticas que os contem |
GR900100137A GR1000869B (el) | 1989-02-24 | 1990-02-22 | Νέες συν?έσεις που περιέχουν συνδυασμούς (συζευγμένους εταίρους)υαλουρονικού οξέος και μέ?οδος για την παρασκευή τους. |
SK857-90A SK279530B6 (sk) | 1989-02-24 | 1990-02-22 | Asociáty deprotonovanej kyseliny hyalurónovej, spô |
MYPI90000280A MY105168A (en) | 1989-02-24 | 1990-02-22 | Novel compositions containing hyaluronic acid associates and a process for preparing same. |
DD90338061A DD292263A5 (de) | 1989-02-24 | 1990-02-22 | Verfahren zur herstellung neuer assoziate der hyaluronsaeure |
IL9348990A IL93489A (en) | 1989-02-24 | 1990-02-22 | Protons of hyaluronic acid without protons with ions of D3 metals of the fourth cycle of the periodic table, their preparation and preparations containing them |
IE63790A IE62408B1 (en) | 1989-02-24 | 1990-02-22 | Novel compositions containing hyaluronic acid associates and a process for preparing same |
ZA901357A ZA901357B (en) | 1989-02-24 | 1990-02-22 | Novel compositions containing hyaluronic acid associates and a process for preparing same |
PL90283942A PL163417B1 (pl) | 1989-02-24 | 1990-02-23 | Sposób wytwarzania nowych kompleksów deprotonowanego kwasu hialuronowego z jonami metalu 3d czwartego okresu ukladu okresowego pierwiastkówUrzad Patentowy Rzeczypospolitej Polskiej PL PL PL PL PL PL PL |
CN93109689A CN1051228C (zh) | 1989-02-24 | 1990-02-23 | 含透明质酸配合物的药物组合物的制备方法 |
CN90100904A CN1024557C (zh) | 1989-02-24 | 1990-02-23 | 透明质酸配合物的制备方法 |
AR90316230A AR243538A1 (es) | 1989-02-24 | 1990-02-23 | Preparacion de complejos de acido hialuronico desprotonado con iones metalicos y composiciones que lo contienen |
FI905109A FI101707B (fi) | 1989-02-24 | 1990-10-17 | Menetelmä uusien terapeuttisesti aktiivisten, deprotonoidusta hyaluron ihaposta ja sinkki- tai koboltti-ioneista muodostuvien tuotteiden valm istamiseksi |
NO904584A NO301169B1 (no) | 1989-02-24 | 1990-10-23 | Analogifremgangsmåte for fremstilling av terapeutisk aktive komplekser av deprotonisert hyaluronsyre |
SU914895005A RU2021304C1 (ru) | 1989-02-24 | 1991-04-11 | Способ получения биологически активной композиции |
US07/928,154 US5554598A (en) | 1989-02-24 | 1992-08-10 | Method of treating crural or decubitus ulcer with zinc hyaluroric acid complex |
US07/949,030 US5472950A (en) | 1989-02-24 | 1992-09-22 | Compositions containing cobalt hyaluronic acid complex |
LVP-92-687A LV10112B (en) | 1989-02-24 | 1992-12-30 | Associations of deprotonated hyaluronic acid, compositions containing it, method for preparing thereof, process for preparing water solution of hyaluronic acid zinc salt |
GEAP1993894A GEP19981358B (en) | 1989-02-24 | 1993-06-17 | Associates of Deprotonated Hyaluronic Acid with Zinc and Cobolt Ions, Method for theirs Production, CompositionCon¬taining the Same and Method for Ob¬taining Medicinal Composition |
LVP-93-747A LV10965B (en) | 1989-02-24 | 1993-06-29 | Process for producing of compositions conteining hyaluronic acid associate |
GEAP19931400A GEP19971015B (en) | 1989-02-24 | 1993-08-12 | Novel compositions containing hyaluronic acid associates and a process for preparing same |
LTIP1418A LT3806B (en) | 1989-02-24 | 1993-10-26 | Hyaluronic acid associates, composition containing them, process for preparing the composition, process for preparing zinc hyaluronate aqueous solution |
LTIP1474A LT3873B (en) | 1989-02-24 | 1993-11-18 | Compositions containing deprotonated hyaluronic acid associates and procrss for preparing same |
BG098631A BG61515B2 (bg) | 1989-02-24 | 1994-03-01 | Нови състави,съдържащи асоциати на хиалуроновата киселина и метод за получаването им |
US08/345,233 US6458774B1 (en) | 1989-02-24 | 1994-11-25 | Compositions containing hyaluronic acid associates and a process for preparing same |
HU95P/P00167P HU211465A9 (en) | 1989-02-24 | 1995-06-07 | Novel compositions containing hyaluronic acid associates and a process for preparing the same |
HK98102052A HK1003003A1 (en) | 1989-02-24 | 1998-03-12 | Novel compositions containing hyaluronic acid associates and a process for preparing same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU89891A HU203372B (en) | 1989-02-24 | 1989-02-24 | Process for producing hyaluronic associates and pharmaceutical compositions and cosmetics comprising such active ingredient |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT53128A true HUT53128A (en) | 1990-09-28 |
HU203372B HU203372B (en) | 1991-07-29 |
Family
ID=10951903
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU89891A HU203372B (en) | 1989-02-24 | 1989-02-24 | Process for producing hyaluronic associates and pharmaceutical compositions and cosmetics comprising such active ingredient |
HU95P/P00167P HU211465A9 (en) | 1989-02-24 | 1995-06-07 | Novel compositions containing hyaluronic acid associates and a process for preparing the same |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU95P/P00167P HU211465A9 (en) | 1989-02-24 | 1995-06-07 | Novel compositions containing hyaluronic acid associates and a process for preparing the same |
Country Status (33)
Country | Link |
---|---|
US (1) | US5554598A (hu) |
EP (1) | EP0413016B1 (hu) |
JP (1) | JP2571312B2 (hu) |
KR (1) | KR960015624B1 (hu) |
CN (2) | CN1024557C (hu) |
AR (1) | AR243538A1 (hu) |
AT (1) | ATE98964T1 (hu) |
AU (1) | AU623232B2 (hu) |
BG (1) | BG61515B2 (hu) |
CA (1) | CA2027596C (hu) |
CZ (1) | CZ281000B6 (hu) |
DD (1) | DD292263A5 (hu) |
DE (1) | DE69005394T2 (hu) |
DK (1) | DK0413016T3 (hu) |
ES (1) | ES2061016T3 (hu) |
FI (1) | FI101707B (hu) |
GE (2) | GEP19981358B (hu) |
GR (1) | GR1000869B (hu) |
HK (1) | HK1003003A1 (hu) |
HU (2) | HU203372B (hu) |
IE (1) | IE62408B1 (hu) |
IL (1) | IL93489A (hu) |
LT (2) | LT3806B (hu) |
LV (2) | LV10112B (hu) |
MY (1) | MY105168A (hu) |
NO (1) | NO301169B1 (hu) |
PL (1) | PL163417B1 (hu) |
PT (1) | PT93237B (hu) |
RU (2) | RU2099350C1 (hu) |
SK (1) | SK279530B6 (hu) |
UA (2) | UA26324A (hu) |
WO (1) | WO1990010020A1 (hu) |
ZA (1) | ZA901357B (hu) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR920100122A (el) * | 1991-04-05 | 1993-03-16 | Ethicon Inc | Πολυσακχαρίτες οι οποίοι περιέχουν καρβοξύλιο με σταυροειδείς δεσμούς δια την πρόληψιν της προσφύσεως. |
DE4115454A1 (de) * | 1991-05-11 | 1992-11-12 | Basf Ag | Eisen-(iii)-hyaluronate |
US5531716A (en) * | 1993-09-29 | 1996-07-02 | Hercules Incorporated | Medical devices subject to triggered disintegration |
IT1273742B (it) * | 1994-08-01 | 1997-07-09 | Lifegroup Spa | Composizioni ad elevata bioadesivita' e mucoadesivita' utili per il trattamento di epitali e mucose |
CN1064372C (zh) * | 1994-08-26 | 2001-04-11 | 顾其胜 | 透明质酸钠制剂的制备方法 |
US6368356B1 (en) | 1996-07-11 | 2002-04-09 | Scimed Life Systems, Inc. | Medical devices comprising hydrogel polymers having improved mechanical properties |
HU225329B1 (en) * | 1996-09-12 | 2006-09-28 | Richter Gedeon Vegyeszet | Use of zinc or cobalt hyaluronate associate for the manufacture of pharmaceutical compositions of antimicrobial activity |
HU225991B1 (en) * | 1997-04-29 | 2008-02-28 | Richter Gedeon Nyrt | Use of the zinc hyaluronate associate (complex) for the preparation of pharmaceutical compositions for oral use against peptic ulcer |
US5906997A (en) * | 1997-06-17 | 1999-05-25 | Fzio Med, Inc. | Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions |
US7192984B2 (en) | 1997-06-17 | 2007-03-20 | Fziomed, Inc. | Compositions of polyacids and polyethers and methods for their use as dermal fillers |
US6869938B1 (en) | 1997-06-17 | 2005-03-22 | Fziomed, Inc. | Compositions of polyacids and polyethers and methods for their use in reducing adhesions |
JP2003089647A (ja) | 1999-03-10 | 2003-03-28 | Takada Seiyaku Kk | 関節性疾患治療剤 |
US6566345B2 (en) | 2000-04-28 | 2003-05-20 | Fziomed, Inc. | Polyacid/polyalkylene oxide foams and gels and methods for their delivery |
US6913765B2 (en) | 2001-03-21 | 2005-07-05 | Scimed Life Systems, Inc. | Controlling resorption of bioresorbable medical implant material |
CZ12015U1 (cs) * | 2002-01-18 | 2002-02-25 | Cpn Spol. S R.O. | Přípravek pro prevenci adheze bandáľe na ránu |
GB2392913B (en) * | 2002-09-11 | 2007-04-04 | Johnson & Johnson Medical Ltd | Wound dressings comprising complexes of oxidised celluloses with silver |
WO2004024197A1 (en) | 2002-09-11 | 2004-03-25 | Johnson & Johnson Medical Limited | Wound dressing materials comprising complexes of anionic polysaccharides with silver |
HUP0303779A2 (en) * | 2003-11-20 | 2006-02-28 | Richter Gedeon Vegyeszet | Pharmaceutical compositions containing hyaluronan complex for the treatment of sclerosis multiplex |
JPWO2006121209A1 (ja) * | 2005-05-13 | 2008-12-18 | 高田製薬株式会社 | 湿疹・皮膚炎群治療剤 |
WO2006121210A1 (ja) * | 2005-05-13 | 2006-11-16 | Takata Seiyaku Co., Ltd. | 皮膚状態改善剤 |
JP4220513B2 (ja) * | 2005-12-01 | 2009-02-04 | 株式会社資生堂 | カチオン化ヒアルロン酸 |
CN100348621C (zh) | 2005-12-02 | 2007-11-14 | 凌沛学 | 透明质酸铋及其制备方法和应用 |
CN1329414C (zh) * | 2005-12-02 | 2007-08-01 | 凌沛学 | 透明质酸铋钾及其制备方法和应用 |
FR2918565B1 (fr) * | 2007-07-12 | 2009-10-30 | Biopharmex Holding Sa | Hydrogel de carboxyalkylamide de chitosan, sa preparation et son utilisation cosmetique et dermatologique |
ES2326721B1 (es) * | 2008-01-04 | 2010-07-16 | Endor Nanotechnologies, S.L. | Conjugado de acido hialuronico para el tratamiento cosmetico y procedimiento de preparacion. |
TWI383796B (zh) | 2009-08-14 | 2013-02-01 | Holy Stone Healthcare Co Ltd | Use of hyaluronic acid mixture for the treatment and prevention of peptic ulcer and duodenal ulcer |
TWI516269B (zh) | 2009-08-14 | 2016-01-11 | 禾伸堂生技股份有限公司 | 使用於炎症性腸疾病(ibd)治療和預防之透明質酸混合物 |
HUP0900717A3 (en) | 2009-11-18 | 2012-02-28 | Richter Gedeon Nyrt | Pharmaceutical composition for urological use containing zinc hyaluronate |
WO2011129370A1 (ja) | 2010-04-14 | 2011-10-20 | キユーピー株式会社 | ヒアルロン酸金属塩の製造方法、ヒアルロン酸金属塩を含む化粧品の製造方法、ならびにヒアルロン酸亜鉛およびその製造方法 |
ES2376680B8 (es) | 2010-08-16 | 2013-04-30 | Nylstar, S.A. | Fibra textil cosmética, procedimiento de obtención y su empleo. |
CN102552309B (zh) * | 2010-12-15 | 2013-06-05 | 北京理工大学 | 一种透明质酸金的用途及其制备方法 |
JP5763953B2 (ja) * | 2011-03-31 | 2015-08-12 | ロート製薬株式会社 | 外用組成物 |
CN102961396A (zh) * | 2012-12-17 | 2013-03-13 | 程玉李 | 透明质酸金属盐在制备治疗皮肤病药物中的应用、其药物组合物及其制备方法 |
JP2016535781A (ja) | 2013-11-03 | 2016-11-17 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 経皮薬物送達のためのイオン性液体 |
JP7179354B2 (ja) * | 2016-08-29 | 2022-11-29 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 皮膚処置のためのイオン種に基づく局所処方物 |
EP3515511A1 (en) | 2016-09-21 | 2019-07-31 | Nestlé Skin Health SA | Hyaluronic acid gel with a divalent zinc cation |
WO2019001784A1 (en) | 2017-06-28 | 2019-01-03 | Nestlé Skin Health Sa | HYALURONIC ACID GEL WITH A DIVALENT CATION |
KR102665710B1 (ko) | 2017-08-24 | 2024-05-14 | 노보 노르디스크 에이/에스 | Glp-1 조성물 및 그 용도 |
US20230082544A1 (en) | 2020-02-18 | 2023-03-16 | Novo Nordisk A/S | Pharmaceutical formulations |
CN111647100B (zh) * | 2020-07-14 | 2022-03-01 | 山东华熙海御生物医药有限公司 | 一种高分子量透明质酸锌的制备方法 |
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US441973A (en) | 1890-12-02 | rapieff | ||
US3074927A (en) * | 1960-04-12 | 1963-01-22 | Paul D Saltman | Metallic complexes of reducing sugars |
US4141973A (en) * | 1975-10-17 | 1979-02-27 | Biotrics, Inc. | Ultrapure hyaluronic acid and the use thereof |
HU172831B (hu) * | 1976-03-31 | 1978-12-28 | Egyt Gyogyszervegyeszeti Gyar | Sposob poluchenija kompleksov oligo- i poligalakturonnyk kislot s ionami zhiznenno vazhnykh metallov |
US4303676A (en) | 1980-03-21 | 1981-12-01 | Balazs Endre A | Hyaluronate based compositions and cosmetic formulations containing same |
IT1229075B (it) | 1985-04-05 | 1991-07-17 | Fidia Farmaceutici | Medicamenti per uso topico, ottenuti tramite l'impiego dell'acido ialuronico |
US4623539A (en) | 1983-02-04 | 1986-11-18 | Tunc Deger C | Nutrient barrier polysaccharide compositions and method of use |
NO161573C (no) | 1983-11-25 | 1989-08-30 | Miles Inc | Fremgangsmaate til fremstilling av hyaluronsyre. |
JPS61286310A (ja) * | 1985-06-10 | 1986-12-16 | Kanebo Ltd | メ−クアツプ化粧料 |
US4746504A (en) * | 1986-03-14 | 1988-05-24 | Bio-Technology General Corp. | Heavy metal salts of hyaluronic acid and their use as antimicrobial agents |
WO1987005517A1 (en) * | 1986-03-14 | 1987-09-24 | Bio-Technology General Corp. | Heavy metal salts of hyaluronic acid useful as antimicrobial agents |
US4742215A (en) * | 1986-05-07 | 1988-05-03 | Personal Computer Card Corporation | IC card system |
JP2511829B2 (ja) * | 1987-03-19 | 1996-07-03 | アースロファーム ピーティーワイ.リミティッド | 抗炎症作用のある化合物および組成物 |
-
1989
- 1989-02-24 HU HU89891A patent/HU203372B/hu unknown
-
1990
- 1990-02-20 DK DK90903397.9T patent/DK0413016T3/da not_active Application Discontinuation
- 1990-02-20 DE DE69005394T patent/DE69005394T2/de not_active Expired - Lifetime
- 1990-02-20 UA UA4895005A patent/UA26324A/uk unknown
- 1990-02-20 JP JP2503644A patent/JP2571312B2/ja not_active Expired - Lifetime
- 1990-02-20 RU SU904831382A patent/RU2099350C1/ru active
- 1990-02-20 AT AT90903397T patent/ATE98964T1/de not_active IP Right Cessation
- 1990-02-20 KR KR1019900702327A patent/KR960015624B1/ko not_active IP Right Cessation
- 1990-02-20 AU AU51088/90A patent/AU623232B2/en not_active Expired
- 1990-02-20 ES ES90903397T patent/ES2061016T3/es not_active Expired - Lifetime
- 1990-02-20 EP EP90903397A patent/EP0413016B1/en not_active Expired - Lifetime
- 1990-02-20 WO PCT/HU1990/000013 patent/WO1990010020A1/en active IP Right Grant
- 1990-02-20 CA CA002027596A patent/CA2027596C/en not_active Expired - Lifetime
- 1990-02-20 UA UA94061636A patent/UA39174C2/uk unknown
- 1990-02-22 GR GR900100137A patent/GR1000869B/el not_active IP Right Cessation
- 1990-02-22 IL IL9348990A patent/IL93489A/en not_active IP Right Cessation
- 1990-02-22 PT PT93237A patent/PT93237B/pt active IP Right Grant
- 1990-02-22 SK SK857-90A patent/SK279530B6/sk not_active IP Right Cessation
- 1990-02-22 ZA ZA901357A patent/ZA901357B/xx unknown
- 1990-02-22 DD DD90338061A patent/DD292263A5/de not_active IP Right Cessation
- 1990-02-22 IE IE63790A patent/IE62408B1/en not_active IP Right Cessation
- 1990-02-22 MY MYPI90000280A patent/MY105168A/en unknown
- 1990-02-22 CZ CS90857A patent/CZ281000B6/cs not_active IP Right Cessation
- 1990-02-23 PL PL90283942A patent/PL163417B1/pl unknown
- 1990-02-23 CN CN90100904A patent/CN1024557C/zh not_active Expired - Lifetime
- 1990-02-23 AR AR90316230A patent/AR243538A1/es active
- 1990-02-23 CN CN93109689A patent/CN1051228C/zh not_active Expired - Lifetime
- 1990-10-17 FI FI905109A patent/FI101707B/fi active IP Right Grant
- 1990-10-23 NO NO904584A patent/NO301169B1/no not_active IP Right Cessation
-
1991
- 1991-04-11 RU SU914895005A patent/RU2021304C1/ru active
-
1992
- 1992-08-10 US US07/928,154 patent/US5554598A/en not_active Expired - Lifetime
- 1992-12-30 LV LVP-92-687A patent/LV10112B/lv unknown
-
1993
- 1993-06-17 GE GEAP1993894A patent/GEP19981358B/en unknown
- 1993-06-29 LV LVP-93-747A patent/LV10965B/lv unknown
- 1993-08-12 GE GEAP19931400A patent/GEP19971015B/en unknown
- 1993-10-26 LT LTIP1418A patent/LT3806B/lt not_active IP Right Cessation
- 1993-11-18 LT LTIP1474A patent/LT3873B/lt not_active IP Right Cessation
-
1994
- 1994-03-01 BG BG098631A patent/BG61515B2/bg unknown
-
1995
- 1995-06-07 HU HU95P/P00167P patent/HU211465A9/hu unknown
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1998
- 1998-03-12 HK HK98102052A patent/HK1003003A1/xx not_active IP Right Cessation
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HC9A | Change of name, address |
Owner name: RICHTER GEDEON NYRT., HU Free format text: FORMER OWNER(S): RICHTER GEDEON VEGYESZETI GYAR RT., HU |