HUP0303576A2 - Microprotrusion member retainer for impact applicator - Google Patents

Microprotrusion member retainer for impact applicator

Info

Publication number
HUP0303576A2
HUP0303576A2 HU0303576A HUP0303576A HUP0303576A2 HU P0303576 A2 HUP0303576 A2 HU P0303576A2 HU 0303576 A HU0303576 A HU 0303576A HU P0303576 A HUP0303576 A HU P0303576A HU P0303576 A2 HUP0303576 A2 HU P0303576A2
Authority
HU
Hungary
Prior art keywords
microprotrusions
epithelium
applicator
microprotrusion member
member retainer
Prior art date
Application number
HU0303576A
Other languages
English (en)
Inventor
Richard L Keenan
Joseph C Trautman
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of HUP0303576A2 publication Critical patent/HUP0303576A2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205Vaccinating by means of needles or other puncturing devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00747Dermatology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles

Abstract

A találmány tárgya szerkezet gyógyszert a bőrön keresztül bevezetőrendszerhez és eljárás a szerkezet használatára. A találmány szerintiszerkezet mikrokiemelkedéseket tartalmazó tagot (44) tartalmaz,amelyen hámréteget átlyukasztó mikrokiemelkedések vannak. Amikrokiemelkedések úgy vannak kiképezve, hogy megnövelik atranszdermális anyagáramot a hámrétegben. A szerkezet továbbá olyanrögzítőgyűrűt (34) tartalmaz, amely oldhatóan van rögzítve amikrokiemelkedéseket tartalmazó taghoz (44) és amely egy tapasztóberendezéshez csatlakoztatható. A találmány szerinti eljárás hatóanyagtranszdermális bevitelére vagy testnedv mintavételére szolgál. Azeljárás során elővesznek egy lezárt csomagolásban lévő,mikrokiemelkedéseket tartalmazó tagot (44) tartó rögzítőgyűrűt (34);felnyitják a csomagolást; a rögzítőgyűrűt (34) csatlakoztatják egyaplikátorhoz; és a mikrokiemelkedéseket tartalmazó tagot (44) azaplikátor segítségével a hámrétegre tapasztják. Ó
HU0303576A 2000-10-13 2001-10-12 Microprotrusion member retainer for impact applicator HUP0303576A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24037900P 2000-10-13 2000-10-13
PCT/US2001/031837 WO2002030300A2 (en) 2000-10-13 2001-10-12 Microprotrusion member retainer for impact applicator

Publications (1)

Publication Number Publication Date
HUP0303576A2 true HUP0303576A2 (en) 2004-01-28

Family

ID=22906291

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303576A HUP0303576A2 (en) 2000-10-13 2001-10-12 Microprotrusion member retainer for impact applicator

Country Status (25)

Country Link
US (3) US6855131B2 (hu)
EP (1) EP1341452B1 (hu)
JP (1) JP4104975B2 (hu)
KR (1) KR20030068137A (hu)
CN (1) CN1479589A (hu)
AT (1) ATE416692T1 (hu)
AU (2) AU9681701A (hu)
BR (1) BR0114628A (hu)
CA (1) CA2425312C (hu)
CZ (1) CZ20031302A3 (hu)
DE (1) DE60136951D1 (hu)
DK (1) DK1341452T3 (hu)
ES (1) ES2317940T3 (hu)
HK (1) HK1058890A1 (hu)
HU (1) HUP0303576A2 (hu)
IL (1) IL155389A0 (hu)
MA (1) MA26058A1 (hu)
MX (1) MXPA03003303A (hu)
NO (1) NO20031680L (hu)
NZ (1) NZ525295A (hu)
PL (1) PL360977A1 (hu)
PT (1) PT1341452E (hu)
RU (1) RU2278623C2 (hu)
WO (1) WO2002030300A2 (hu)
ZA (1) ZA200303631B (hu)

Families Citing this family (153)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6230051B1 (en) * 1996-06-18 2001-05-08 Alza Corporation Device for enhancing transdermal agent delivery or sampling
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
CN1250171C (zh) * 2000-10-13 2006-04-12 阿尔扎公司 利用微凸起刺入皮肤的装置和方法
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
MXPA03003303A (es) * 2000-10-13 2004-12-13 Johnson & Johnson Retenedor del miembro de microprotrusion para aplicador de impacto.
US7108681B2 (en) 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
ATE428466T1 (de) * 2000-10-26 2009-05-15 Alza Corp Transdermales arzneistoffverabreichungssytem mit beschichteten mikrovorsprüngen
WO2002074173A1 (en) * 2001-03-16 2002-09-26 Alza Corporation Method and apparatus for coating skin piercing microprojections
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
MXPA03009603A (es) * 2001-04-20 2004-12-06 Johnson & Johnson Arreglo de microproyeccion que tiene un agente benefico que contiene un recubrimiento.
US6881203B2 (en) * 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
JP2005511248A (ja) * 2001-10-29 2005-04-28 ベクトン・ディキンソン・アンド・カンパニー 物質を送達するための方法およびデバイス
US20040120964A1 (en) * 2001-10-29 2004-06-24 Mikszta John A. Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
EP1485317A2 (en) * 2001-11-30 2004-12-15 Alza Corporation Methods and apparatuses for forming microprojection arrays
DE60223844T2 (de) * 2001-12-20 2008-08-28 Alza Corp., Mountain View Mikrovorsprünge zum durchstechen der haut mit stechtiefensteuerung
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
CA2497154C (en) * 2002-08-29 2012-01-03 Becton, Dickinson And Company Substance delivery via a rotating microabrading surface
US20040115167A1 (en) * 2002-09-30 2004-06-17 Michel Cormier Drug delivery device and method having coated microprojections incorporating vasoconstrictors
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
ES2293273T3 (es) * 2003-06-12 2008-03-16 Disetronic Licensing Ag Dispositivo de insercion para equipos de infusion.
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
CA2530531A1 (en) * 2003-06-30 2005-01-20 Alza Corporation Formulations for coated microprojections containing non-volatile counterions
AR044985A1 (es) * 2003-07-02 2005-10-12 Alza Corp Metodo y parche de inmunizacion por disposicion de microproyeccion
US20050049549A1 (en) * 2003-08-04 2005-03-03 Wong Patrick S.L. Method and device for enhancing transdermal agent flux
US20050070876A1 (en) * 2003-09-26 2005-03-31 Penjet Corporation Method and apparatus for administering a vaccine or other pharmaceutical
WO2005042702A2 (en) * 2003-10-23 2005-05-12 Alza Corporation Compositions of stabilized dna for coating microprojections
JP2007508914A (ja) * 2003-10-24 2007-04-12 アルザ・コーポレーシヨン 経皮薬剤送達を促進するための装置及び方法
JP2007510445A (ja) * 2003-10-24 2007-04-26 アルザ・コーポレーシヨン 経皮薬剤送達促進用の前処置法及びシステム
BRPI0415986A (pt) * 2003-10-28 2007-01-23 Alza Corp método e aparelho para reduzir a incidência do uso de tabaco
AU2004287059A1 (en) * 2003-10-28 2005-05-19 Alza Corporation Delivery of polymer conjugates of therapeutic peptides and proteins via coated microporjections
JP4682144B2 (ja) * 2003-10-31 2011-05-11 アルザ・コーポレーシヨン 微小突起列のための自己−作動性アプリケーター
MXPA06005677A (es) * 2003-11-21 2006-12-14 Johnson & Johnson Metodo y sistema de suministro transdermico de vacuna asistido por ultrasonido.
EP1706171A1 (en) * 2003-12-29 2006-10-04 3M Innovative Properties Company Medical devices and kits including same
DE502004005579D1 (de) * 2003-12-30 2008-01-03 Disetronic Licensing Ag INSERTIONSVORRICHTUNG FüR DURCHSTECHVORRICHTUNGEN
WO2005094526A2 (en) 2004-03-24 2005-10-13 Corium International, Inc. Transdermal delivery device
JP4971133B2 (ja) * 2004-04-01 2012-07-11 ザ ジェネラル ホスピタル コーポレイション 皮膚科治療のための装置
CN101027045A (zh) * 2004-04-13 2007-08-29 阿尔扎公司 基于芬太尼药物的透皮释放装置和方法
KR20070011481A (ko) * 2004-04-13 2007-01-24 알자 코포레이션 다중 백신의 경피 전달용 기구 및 방법
AU2005244734A1 (en) 2004-05-13 2005-12-01 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
WO2005123173A1 (en) * 2004-06-10 2005-12-29 3M Innovative Properties Company Patch application device and kit
US20060030811A1 (en) * 2004-08-03 2006-02-09 Wong Patrick S Method and device for enhancing transdermal agent flux
TW200618830A (en) * 2004-08-10 2006-06-16 Alza Corp Micorprojection apparatus and system with low infection potential
AR050608A1 (es) * 2004-08-19 2006-11-08 Alza Corp Aparato y metodo para administracion transdermica de factores de crecimiento endotelial vascular
KR20070099540A (ko) * 2004-09-08 2007-10-09 알자 코포레이션 향상된 피부 점착성 및 순응도를 갖는 미세돌출부 어레이
US20060093658A1 (en) * 2004-10-26 2006-05-04 Gayatri Sathyan Apparatus and method for transdermal delivery of desmopressin
JP2008520367A (ja) * 2004-11-18 2008-06-19 スリーエム イノベイティブ プロパティズ カンパニー 皮膚非接触型のマイクロニードルアレイアプリケータ
KR101224257B1 (ko) * 2004-11-18 2013-01-18 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로니들 어레이를 코팅하기 위한 마스킹 방법
BRPI0517749A (pt) 2004-11-18 2008-10-21 3M Innovative Properties Co dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação
US9174035B2 (en) 2004-11-18 2015-11-03 3M Innovative Properties Company Microneedle array applicator and retainer
JP5015787B2 (ja) 2004-11-18 2012-08-29 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの接触コーティング法
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
AU2006214236A1 (en) * 2005-02-16 2006-08-24 Alza Corporation Apparatus and method for transdermal delivery of erythropoetin-based agents
WO2006108185A1 (en) 2005-04-07 2006-10-12 3M Innovative Properties Company System and method for tool feedback sensing
WO2006130869A1 (en) * 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices
US20060280644A1 (en) * 2005-06-02 2006-12-14 Scott Sellers Method for terminal sterilization of transdermal delivery devices
EP1904158B1 (en) * 2005-06-24 2013-07-24 3M Innovative Properties Company Collapsible patch with microneedle array
ATE477833T1 (de) * 2005-06-27 2010-09-15 3M Innovative Properties Co Mikronadelkartuschenanordnung
JP5144510B2 (ja) 2005-06-27 2013-02-13 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイ適用装置
US20070078414A1 (en) * 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
CN101242869B (zh) * 2005-09-02 2010-05-26 Iomai公司 经皮递送疫苗和透皮递送药物的装置及其应用
CN101267896A (zh) * 2005-09-12 2008-09-17 阿尔扎公司 可涂覆的透皮给药微突起组合件
WO2007064486A1 (en) 2005-11-30 2007-06-07 3M Innovative Properties Company Microneedle arrays and methods of use thereof
AU2006336187A1 (en) * 2005-12-28 2007-07-26 Alza Corporation Stable therapeutic formulations
US7658728B2 (en) * 2006-01-10 2010-02-09 Yuzhakov Vadim V Microneedle array, patch, and applicator for transdermal drug delivery
JP4963849B2 (ja) 2006-03-13 2012-06-27 シスメックス株式会社 微細孔形成システム
AU2007225056A1 (en) * 2006-03-15 2007-09-20 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia
WO2007124411A1 (en) * 2006-04-20 2007-11-01 3M Innovative Properties Company Device for applying a microneedle array
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
WO2007127815A2 (en) * 2006-04-25 2007-11-08 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
WO2008091602A2 (en) 2007-01-22 2008-07-31 Corium International, Inc. Applicators for microneedle arrays
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
WO2008130587A2 (en) 2007-04-16 2008-10-30 Corium International, Inc. Solvent-cast microneedle arrays containing active
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
WO2009107806A2 (ja) * 2008-02-29 2009-09-03 株式会社メドレックス マイクロニードルの皮膚内への挿入方法及び該方法に使用する補助器具
EP2429627B1 (en) * 2009-04-24 2017-06-14 Corium International, Inc. Methods for manufacturing microprojection arrays
WO2011005894A1 (en) * 2009-07-07 2011-01-13 Naya Touch, Inc. Dermal roller with therapeutic microstructures
AU2011248108B2 (en) 2010-05-04 2016-05-26 Corium Pharma Solutions, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
US9687640B2 (en) 2010-05-04 2017-06-27 Corium International, Inc. Applicators for microneedles
JP5562138B2 (ja) * 2010-06-24 2014-07-30 シスメックス株式会社 微細孔形成装置
US8540672B2 (en) 2010-12-22 2013-09-24 Valeritas, Inc. Microneedle patch applicator
JP5687170B2 (ja) * 2011-03-30 2015-03-18 コスメディ製薬株式会社 マイクロニードルパッチ収納容器
WO2012170497A2 (en) * 2011-06-09 2012-12-13 3M Innovative Properties Company Microstructure device with removable microstructure patch
JP6265740B2 (ja) 2011-10-06 2018-01-24 久光製薬株式会社 アプリケータ
IN2014CN02637A (hu) * 2011-10-12 2015-08-07 3M Innovative Properties Co
JP6226862B2 (ja) * 2012-04-05 2017-11-08 久光製薬株式会社 穿刺装置及びその製造方法
JP5903016B2 (ja) 2012-06-27 2016-04-13 コスメディ製薬株式会社 マイクロニードルパッチの保護離型シート
JP6091818B2 (ja) * 2012-08-28 2017-03-08 コスメディ製薬株式会社 マイクロニードルパッチ投与装置
JP6009302B2 (ja) * 2012-09-27 2016-10-19 シスメックス株式会社 微細孔形成装置、微細針チップおよびチップホルダ
JP5719005B2 (ja) * 2012-09-27 2015-05-13 コスメディ製薬株式会社 マイクロニードルパッチ収納容器2
WO2014059104A1 (en) 2012-10-10 2014-04-17 3M Innovative Properties Company Applicator and method for applying a microneedle device to skin
EP2906284B8 (en) 2012-10-10 2021-01-20 Kindeva Drug Delivery L.P. Force-controlled applicator for applying a microneedle device to skin
EP2919849B1 (en) * 2012-11-16 2021-01-06 Kindeva Drug Delivery L.P. Force-controlled applicator for applying a microneedle device to skin
KR102378235B1 (ko) 2012-12-14 2022-03-25 민데라 코포레이션 바이오마커의 검출 및 취득을 위한 방법 및 디바이스
CN105073178B (zh) 2012-12-21 2019-07-30 考里安国际公司 用于治疗剂递送的微阵列及其使用方法
KR102236575B1 (ko) 2012-12-21 2021-04-05 쓰리엠 이노베이티브 프로퍼티즈 컴파니 접착제 조립체 및 이를 포함하는 마이크로니들 주사 장치
EP2937111B1 (en) * 2012-12-21 2020-03-18 Hisamitsu Pharmaceutical Co., Inc. Applicator
CA2901568C (en) * 2013-02-28 2021-02-16 Kimberly-Clark Worldwide, Inc. Transdermal drug delivery device
WO2014164314A1 (en) 2013-03-12 2014-10-09 Corium International, Inc. Microprojection applicators
JP2016512754A (ja) 2013-03-15 2016-05-09 コリウム インターナショナル, インコーポレイテッド 治療剤の送達のためのマイクロアレイ、使用方法および製造方法
EP2968116A1 (en) 2013-03-15 2016-01-20 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
WO2014150285A2 (en) 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
EP2968118B1 (en) 2013-03-15 2022-02-09 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
JP6251298B2 (ja) 2013-05-31 2017-12-20 スリーエム イノベイティブ プロパティズ カンパニー 逆作動アクチュエータを備えるマイクロニードル注射装置
SG11201509810TA (en) 2013-05-31 2015-12-30 3M Innovative Properties Co Microneedle injection and infusion apparatus and method of using same
SG11201509722PA (en) 2013-05-31 2015-12-30 3M Innovative Properties Co Microneedle injection apparatus comprising a dual cover
EP3011992B1 (en) 2013-06-18 2019-10-16 Hisamitsu Pharmaceutical Co., Inc. Applicator
US10039911B2 (en) * 2013-06-19 2018-08-07 Hisamitsu Pharmaceutical Co., Inc. Applicator
US9782344B2 (en) 2013-08-22 2017-10-10 Zp Opco, Inc. Stable glucagon peptide formulations
US9173924B2 (en) 2013-08-22 2015-11-03 Zp Opco, Inc. Stable glucagon peptide formulations
CA2924447C (en) 2013-09-18 2020-08-04 Cosmed Pharmaceutical Co., Ltd. Microneedle patch application device and patch holder
EP3067088B1 (en) 2013-11-05 2019-09-04 Hisamitsu Pharmaceutical Co., Inc. Applicator
AU2015253258B9 (en) * 2014-04-30 2019-09-05 Sorrento Therapeutics, Inc. Receptacle portion of transdermal drug delivery apparatus and methods
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP2017023404A (ja) * 2015-07-22 2017-02-02 日本写真印刷株式会社 マイクロニードルパッチ用インパクト付加型アプリケータ及び先端部材
WO2017038499A1 (ja) 2015-09-02 2017-03-09 久光製薬株式会社 アプリケータ
WO2017079611A1 (en) 2015-11-02 2017-05-11 Zp Opco, Inc. Stable glucagon peptide formulations
ES2928981T3 (es) 2015-12-21 2022-11-23 Medrx Co Ltd Alojamiento para aplicador de parches de microagujas
WO2017143345A1 (en) 2016-02-19 2017-08-24 Zp Opco, Inc. Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines
WO2017159779A1 (ja) 2016-03-16 2017-09-21 コスメディ製薬株式会社 マイクロニードルパッチケース
CA3046795A1 (en) 2016-12-16 2018-06-21 Sorrento Therapeutics, Inc. Attachment band for a fluid delivery apparatus and method of use
AU2017376502B2 (en) 2016-12-16 2023-10-05 Sorrento Therapeutics, Inc. Method for administering a medicament suitable for treating a migraine or cluster headache
JP7008709B2 (ja) 2016-12-16 2022-01-25 ソレント・セラピューティクス・インコーポレイテッド 制御アセンブリを有する流体送達装置及びその使用方法
US10569010B2 (en) 2016-12-16 2020-02-25 Sorrento Therapeutics, Inc. Fluid delivery apparatus having a gas extraction device and method of use
WO2018111616A1 (en) 2016-12-16 2018-06-21 Kimberly-Clark Worldwide, Inc. Application device for a fluid delivery apparatus and method of use
CA3046799A1 (en) 2016-12-16 2018-06-21 Sorrento Therapeutics, Inc. Fluid delivery apparatus and method of assembly
CN110167625B (zh) 2017-01-25 2023-03-03 考司美德制药株式会社 微针贴应用装置
JP6931217B2 (ja) 2017-03-28 2021-09-01 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ
US11660264B2 (en) 2017-08-23 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
KR20210155817A (ko) 2017-08-23 2021-12-23 조사노 파마 코포레이션 편두통 및 군발성 두통의 치료를 위한 졸미트립탄의 치료적 농도를 신속하게 달성하는 방법
DK3675935T3 (da) 2017-08-30 2021-11-08 Pirouette Medical Inc Kompakt autoinjektor
US10441714B2 (en) 2017-10-05 2019-10-15 Pirouette Medical LLC Protective case for an auto-injector
MX2020003699A (es) * 2017-10-17 2020-08-13 Kindeva Drug Delivery Lp Aplicador para aplicar una matriz de microagujas a la piel.
WO2019092957A1 (ja) * 2017-11-07 2019-05-16 ニプロ株式会社 穿刺用器具
BR112020012573A2 (pt) 2017-12-19 2021-03-23 Kindeva Drug Delivery L.P. aplicador de micromatriz
JP7319979B2 (ja) * 2017-12-19 2023-08-02 キンデーバ ドラッグ デリバリー リミティド パートナーシップ マイクロアレイアプリケータ
CN111629772A (zh) 2018-01-24 2020-09-04 考司美德制药株式会社 微针用张紧器具
JP7377818B2 (ja) * 2018-05-01 2023-11-10 シーエスピー テクノロジーズ,インコーポレイティド 薬剤送達デバイス、ならびに薬剤送達デバイスの使用および作製方法
US11660265B2 (en) 2018-06-28 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
DE102019200558A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Mikroarrayaufnahme
DE102019200557A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Applikator
BR112021012283A2 (pt) * 2019-02-28 2021-09-08 Radius Health, Inc. Sistema transdérmico para a administração de abaloparatida e método de uso
JP2020179168A (ja) 2019-04-25 2020-11-05 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ2
JP1664520S (hu) * 2019-09-19 2020-07-27
JP1664599S (hu) * 2019-09-19 2020-07-27
JP1664598S (hu) * 2019-09-19 2020-07-27
US20230028295A1 (en) * 2019-12-18 2023-01-26 Uprax Microsolutions B.V. Applicators and methods for applying a microneedle patch to a skin of a subject, and microneedle patches
US20220062606A1 (en) * 2020-08-28 2022-03-03 City University Of Hong Kong Cryo formulation-based microneedle device for transdermal delivery of bioactive therapeutic agents and cancer immunotherapy using a cryo-microneedle patch
US11951272B2 (en) * 2020-08-28 2024-04-09 City University Of Hong Kong Cryo formulation-based microneedle device for ocular delivery of bioactive therapeutic agents using a cryo-microneedle patch
US11904126B2 (en) * 2020-08-28 2024-02-20 City University Of Hong Kong Cryo formulation-based microneedle device for transdermal delivery of bioactive therapeutic agents and performing vaccination using a cryo-microneedle patch
EP4301225A1 (en) 2021-09-28 2024-01-10 Biolinq Incorporated Microneedle enclosure and applicator device for microneedle array based continuous analyte monitoring device
WO2024059151A1 (en) * 2022-09-13 2024-03-21 Georgia Tech Research Corporation Microneedle application tools and methods

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) 1964-09-08 Means for vaccinating
GB1080986A (en) 1964-09-02 1967-08-31 Allen And Hanburys Surgical En Multiple puncture apparatus
US3322121A (en) * 1965-11-26 1967-05-30 Oscar H Banker Skin-puncturing unit with a collapsible protective cover
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
OA05448A (fr) * 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
GB2064329B (en) * 1979-11-01 1983-06-22 Matburn Holdings Ltd Multiple puncture apparatus
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US5402798A (en) * 1991-07-18 1995-04-04 Swierczek; Remi Disposable skin perforator and blood testing device
NZ291205A (en) 1994-08-18 1997-12-19 Nmt Group Plc Syringe with self retracting offset needle
DE59505328D1 (de) 1994-12-09 1999-04-15 Novartis Ag Transdermales system
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
WO1996037256A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical patch for enhancing the delivery of compounds through the skin
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US5613978A (en) 1996-06-04 1997-03-25 Palco Laboratories Adjustable tip for lancet device
US6230051B1 (en) 1996-06-18 2001-05-08 Alza Corporation Device for enhancing transdermal agent delivery or sampling
DE69722414T2 (de) 1996-07-03 2004-05-19 Altea Therapeutics Corp. Mehrfache mechanische mikroperforierung von haut oder schleimhäuten
GB2317113B (en) 1996-09-13 1998-11-11 Hsiao Ray Ling Skin allergy test assembly
US5983136A (en) * 1996-09-17 1999-11-09 Deka Products Limited Partnership System for delivery of drugs by transport
CN1133472C (zh) 1996-12-20 2004-01-07 阿尔萨公司 增加经皮样剂流量的装置
DE19654391A1 (de) 1996-12-27 1998-07-02 Basf Ag Katalysator zur selektiven Herstellung von Propylen aus Propan
BR9714113A (pt) 1996-12-31 2000-03-21 Shell Int Research Plataforma de tirante
US5986136A (en) * 1997-04-15 1999-11-16 President And Fellows Of Harvard College Photolabeling reagent
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
ATE221400T1 (de) 1997-12-11 2002-08-15 Alza Corp Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
JP2001525227A (ja) 1997-12-11 2001-12-11 アルザ・コーポレーション 経皮的薬剤流量を高めるための装置
DK1037686T3 (da) 1997-12-11 2006-01-02 Alza Corp Apparat til forögelse af transdermal gennemströmning af midler
WO1999064580A1 (en) 1998-06-10 1999-12-16 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
MXPA03003303A (es) 2000-10-13 2004-12-13 Johnson & Johnson Retenedor del miembro de microprotrusion para aplicador de impacto.
CN1250171C (zh) 2000-10-13 2006-04-12 阿尔扎公司 利用微凸起刺入皮肤的装置和方法
ATE428466T1 (de) 2000-10-26 2009-05-15 Alza Corp Transdermales arzneistoffverabreichungssytem mit beschichteten mikrovorsprüngen
WO2002074173A1 (en) 2001-03-16 2002-09-26 Alza Corporation Method and apparatus for coating skin piercing microprojections
MXPA03009603A (es) 2001-04-20 2004-12-06 Johnson & Johnson Arreglo de microproyeccion que tiene un agente benefico que contiene un recubrimiento.
EP1485317A2 (en) 2001-11-30 2004-12-15 Alza Corporation Methods and apparatuses for forming microprojection arrays
DE60223844T2 (de) 2001-12-20 2008-08-28 Alza Corp., Mountain View Mikrovorsprünge zum durchstechen der haut mit stechtiefensteuerung
JP2006500974A (ja) 2002-06-28 2006-01-12 アルザ・コーポレーシヨン 被覆され微細突起物を有する経皮的薬物送達装置
AR042815A1 (es) 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
CA2530531A1 (en) 2003-06-30 2005-01-20 Alza Corporation Formulations for coated microprojections containing non-volatile counterions
AU2004287059A1 (en) 2003-10-28 2005-05-19 Alza Corporation Delivery of polymer conjugates of therapeutic peptides and proteins via coated microporjections
JP4682144B2 (ja) 2003-10-31 2011-05-11 アルザ・コーポレーシヨン 微小突起列のための自己−作動性アプリケーター
EP1682012A4 (en) 2003-11-13 2008-09-24 Alza Corp COMPOSITION AND APPARATUS FOR TRANSDERMAL DELIVERY

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