HU183646B - Vagina ring containing holding ring and coating consists of effective agent - Google Patents
Vagina ring containing holding ring and coating consists of effective agent Download PDFInfo
- Publication number
- HU183646B HU183646B HU813156A HU315681A HU183646B HU 183646 B HU183646 B HU 183646B HU 813156 A HU813156 A HU 813156A HU 315681 A HU315681 A HU 315681A HU 183646 B HU183646 B HU 183646B
- Authority
- HU
- Hungary
- Prior art keywords
- layer
- ring
- drug
- active agent
- active ingredient
- Prior art date
Links
- 239000003795 chemical substances by application Substances 0.000 title description 2
- 239000011248 coating agent Substances 0.000 title description 2
- 238000000576 coating method Methods 0.000 title description 2
- 210000001215 vagina Anatomy 0.000 title 1
- 239000004480 active ingredient Substances 0.000 claims abstract description 16
- 239000006213 vaginal ring Substances 0.000 claims abstract description 11
- 229940044953 vaginal ring Drugs 0.000 claims abstract description 10
- 239000013543 active substance Substances 0.000 claims abstract description 8
- 150000003431 steroids Chemical class 0.000 claims abstract 2
- 229920002379 silicone rubber Polymers 0.000 abstract description 9
- 230000007774 longterm Effects 0.000 abstract 1
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 26
- -1 polyethylene Polymers 0.000 description 22
- 239000000203 mixture Substances 0.000 description 16
- 229940079593 drug Drugs 0.000 description 13
- 239000003814 drug Substances 0.000 description 13
- 229910052697 platinum Inorganic materials 0.000 description 13
- 239000004205 dimethyl polysiloxane Substances 0.000 description 11
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 11
- VMAWODUEPLAHOE-UHFFFAOYSA-N 2,4,6,8-tetrakis(ethenyl)-2,4,6,8-tetramethyl-1,3,5,7,2,4,6,8-tetraoxatetrasilocane Chemical compound C=C[Si]1(C)O[Si](C)(C=C)O[Si](C)(C=C)O[Si](C)(C=C)O1 VMAWODUEPLAHOE-UHFFFAOYSA-N 0.000 description 8
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 7
- 239000003054 catalyst Substances 0.000 description 6
- WWYNJERNGUHSAO-XUDSTZEESA-N (+)-Norgestrel Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 WWYNJERNGUHSAO-XUDSTZEESA-N 0.000 description 5
- 229960004400 levonorgestrel Drugs 0.000 description 5
- 239000004033 plastic Substances 0.000 description 5
- 229920003023 plastic Polymers 0.000 description 5
- 229920001971 elastomer Polymers 0.000 description 4
- 239000004698 Polyethylene Substances 0.000 description 3
- 239000006185 dispersion Substances 0.000 description 3
- 239000000806 elastomer Substances 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 229920000573 polyethylene Polymers 0.000 description 3
- 239000000377 silicon dioxide Substances 0.000 description 3
- 230000003068 static effect Effects 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 239000008186 active pharmaceutical agent Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 229940088679 drug related substance Drugs 0.000 description 2
- 150000003057 platinum Chemical class 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000004073 vulcanization Methods 0.000 description 2
- BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 description 1
- 241000282560 Macaca mulatta Species 0.000 description 1
- ICTXHFFSOAJUMG-SLHNCBLASA-N Norethynodrel Chemical compound C1CC(=O)CC2=C1[C@H]1CC[C@](C)([C@](CC3)(O)C#C)[C@@H]3[C@@H]1CC2 ICTXHFFSOAJUMG-SLHNCBLASA-N 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000001076 estrogenic effect Effects 0.000 description 1
- 229960002568 ethinylestradiol Drugs 0.000 description 1
- CHNXZKVNWQUJIB-CEGNMAFCSA-N ethisterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 CHNXZKVNWQUJIB-CEGNMAFCSA-N 0.000 description 1
- 229960000445 ethisterone Drugs 0.000 description 1
- 230000004720 fertilization Effects 0.000 description 1
- 230000003152 gestagenic effect Effects 0.000 description 1
- SIGSPDASOTUPFS-XUDSTZEESA-N gestodene Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](C=C4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 SIGSPDASOTUPFS-XUDSTZEESA-N 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229940053934 norethindrone Drugs 0.000 description 1
- VIKNJXKGJWUCNN-XGXHKTLJSA-N norethisterone Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 VIKNJXKGJWUCNN-XGXHKTLJSA-N 0.000 description 1
- 229960001858 norethynodrel Drugs 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 229920002631 room-temperature vulcanizate silicone Polymers 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000003270 steroid hormone Substances 0.000 description 1
- 230000003637 steroidlike Effects 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- General Induction Heating (AREA)
- Control And Safety Of Cranes (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803040978 DE3040978A1 (de) | 1980-10-28 | 1980-10-28 | Vaginalring |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU183646B true HU183646B (en) | 1984-05-28 |
Family
ID=6115593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU813156A HU183646B (en) | 1980-10-28 | 1981-10-27 | Vagina ring containing holding ring and coating consists of effective agent |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4822616A (enExample) |
| EP (1) | EP0050867B1 (enExample) |
| JP (2) | JPS5799954A (enExample) |
| AT (1) | ATE31875T1 (enExample) |
| AU (1) | AU7670981A (enExample) |
| BG (1) | BG42182A3 (enExample) |
| CA (1) | CA1165239A (enExample) |
| CS (1) | CS253564B2 (enExample) |
| DD (1) | DD201645A5 (enExample) |
| DE (2) | DE3040978A1 (enExample) |
| DK (1) | DK151529C (enExample) |
| EG (1) | EG15347A (enExample) |
| ES (2) | ES527301A0 (enExample) |
| FI (1) | FI78389C (enExample) |
| GR (1) | GR75367B (enExample) |
| HU (1) | HU183646B (enExample) |
| IE (1) | IE54581B1 (enExample) |
| IL (1) | IL64139A (enExample) |
| NO (1) | NO153753C (enExample) |
| PL (1) | PL127941B1 (enExample) |
| PT (1) | PT73886B (enExample) |
| RO (1) | RO88674A (enExample) |
| SU (1) | SU1440326A3 (enExample) |
| YU (1) | YU252281A (enExample) |
| ZA (1) | ZA817477B (enExample) |
| ZW (1) | ZW26081A1 (enExample) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3347125A1 (de) * | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | Mehrstufenkombinationspraeparat und seine verwendung zur oralen kontrazeption |
| GB8430703D0 (en) * | 1984-12-05 | 1985-01-16 | Lrc Products | Drug release devices |
| FR2618329B1 (fr) * | 1987-07-22 | 1997-03-28 | Dow Corning Sa | Procede de fabrication d'un anneau capable d'assurer la liberation d'un agent therapeutique, et anneau fabrique par ce procede |
| US5295984A (en) | 1989-12-07 | 1994-03-22 | Ultrafem, Inc. | Vaginal discharge collection device and intravaginal drug delivery system |
| US6264638B1 (en) * | 1989-12-07 | 2001-07-24 | Ultrafem, Inc. | Intravaginal drug delivery system and discharge collection device |
| WO1992018101A1 (en) * | 1991-04-12 | 1992-10-29 | The Upjohn Company | Vaginal drug delivery device |
| FI95768C (fi) * | 1993-06-17 | 1996-03-25 | Leiras Oy | Emättimensisäinen antosysteemi |
| GB9326255D0 (en) * | 1993-12-23 | 1994-02-23 | Roussel Lab Ltd | Medical device for the prevention and treatment of cancer |
| ATE207736T1 (de) | 1995-07-04 | 2001-11-15 | Akzo Nobel Nv | Ringförmige vorrichtung |
| GB9522403D0 (en) * | 1995-11-01 | 1996-01-03 | Hoechst Roussel Ltd | Intravaginal drug delivery device |
| US6030375A (en) * | 1996-03-29 | 2000-02-29 | Iotek, Inc. | Compressible vaginal insert and method for treating urogenital disorders |
| US5988169A (en) * | 1996-03-29 | 1999-11-23 | Iotek, Inc. | Vaginal insert and method for treating urogenital disorders |
| US5816248A (en) * | 1996-03-29 | 1998-10-06 | Iotek, Inc. | Channeled vaginal insert and method for treating urogenital disorders |
| WO1998000184A1 (en) | 1996-07-03 | 1998-01-08 | Ultrafem, Inc. | Method and system for manufacturing elastomeric articles |
| US5972372A (en) * | 1996-07-31 | 1999-10-26 | The Population Council, Inc. | Intravaginal rings with insertable drug-containing core |
| TW358031B (en) * | 1997-04-11 | 1999-05-11 | Akze Nobel N V | Drug delivery system for 2 or more active substances |
| US6039968A (en) * | 1997-06-24 | 2000-03-21 | Hoechst Marion Roussel | Intravaginal drug delivery device |
| DE69929055T2 (de) * | 1998-05-01 | 2006-07-20 | Duramed Pharmaceuticals Inc., Cincinnati | Verfahren zur spritzgussherstellung von vorrichtungen mit kontrollierter wirkstofffreisetzung und damit hergestellte vorrichtung |
| AU8672601A (en) | 2000-08-24 | 2002-03-04 | Cornell Res Foundation Inc | Non-hormonal vaginal contraceptive |
| US7226442B2 (en) * | 2000-10-10 | 2007-06-05 | Microchips, Inc. | Microchip reservoir devices using wireless transmission of power and data |
| CN1289064C (zh) * | 2001-08-31 | 2006-12-13 | 先灵有限责任公司 | 药物输送体系 |
| WO2004022033A1 (en) * | 2002-09-04 | 2004-03-18 | Microchips, Inc. | Method and device for the controlled delivery of parathyroid hormone |
| US7357046B2 (en) | 2002-12-16 | 2008-04-15 | N. V. Organon | Method for dissolution testing of a pharmaceutical delivery device |
| AU2004233997C1 (en) * | 2003-04-29 | 2014-01-30 | Massachusetts Institiute Of Technology | Methods and devices for the sustained release of multiple drugs |
| TWI336627B (en) | 2003-05-23 | 2011-02-01 | Organon Nv | Drug delivery system,and use and manufacturing method thereof |
| JP2007530500A (ja) | 2004-03-24 | 2007-11-01 | ナームローゼ・フエンノートチヤツプ・オルガノン | ポリエチレン酢酸ビニル共重合体に基づく薬物送達システム |
| EP1843783B1 (en) * | 2005-01-25 | 2012-05-30 | MicroCHIPS, Inc. | Control of drug release by transient modification of local microenvironments |
| US20080076975A1 (en) * | 2005-01-25 | 2008-03-27 | Microchips, Inc. | Method and implantable device with reservoir array for pre-clinical in vivo testing |
| CN1899643B (zh) * | 2005-07-20 | 2010-12-29 | 上海市计划生育科学研究所 | 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途 |
| US8399012B2 (en) | 2006-04-17 | 2013-03-19 | Kimberly-Clark Worldwide, Inc. | Degradable therapeutic delivery device |
| US8741329B2 (en) | 2007-09-21 | 2014-06-03 | Merck Sharp & Dohme B.V. | Drug delivery system |
| TW200927141A (en) * | 2007-11-22 | 2009-07-01 | Bayer Schering Pharma Oy | Vaginal delivery system |
| JP5507467B2 (ja) | 2008-02-04 | 2014-05-28 | テバ ウィメンズ ヘルス インコーポレイテッド | プロゲステロンを含むモノリシック膣内リングならびにそれらの製造方法および使用 |
| US20100040671A1 (en) * | 2008-08-12 | 2010-02-18 | Ahmed Salah U | Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof |
| US8420153B2 (en) * | 2008-09-19 | 2013-04-16 | Mentor Worldwide Llc | Coating with antimicrobial agents |
| US8419793B2 (en) * | 2008-09-19 | 2013-04-16 | Mentor Worldwide Llc | Coating with antimicrobial agents |
| AU2010256558B2 (en) | 2009-06-03 | 2013-10-03 | Forsight Labs, Llc | Anterior segment drug delivery |
| CA2767967C (en) | 2009-07-21 | 2014-10-21 | The Population Council, Inc. | Multi-layered gradient vaginal ring |
| CA2798220A1 (en) | 2010-05-05 | 2011-11-10 | Teva Women's Health, Inc. | Methods of reducing symptoms in subjects using single dosage forms with tapering release rates |
| US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
| DE202012012713U1 (de) | 2011-03-04 | 2014-01-23 | Arstat, Inc. | Intravaginale Arzneimittelabgabevorrichtung |
| DE202011110355U1 (de) | 2011-03-09 | 2014-01-15 | Arstat, Inc. | Behandlung von Uterusmyomen durch intravaginale Verabreichung einer niedrigen Dosis eines selektiven Progesteronrezeptormodulators, eines Antigestagens oder eines Antigestagen-Wirkstoffes |
| DE202011110356U1 (de) | 2011-03-10 | 2014-01-15 | Arstat, Inc. | Behandlung von Endometriose durch intravaginale Verabreichung einer niedrigen Dosis eines selektiven Progesteronrezeptormodulators, eines Antigestagens oder eines Antigestagen-Wirkstoffes |
| WO2012138542A1 (en) * | 2011-04-07 | 2012-10-11 | Arstat, Inc. | Treatment of menstrual pain and excessive menstrual blood loss by intravaginal administration of a low dose of antifibrinolytic or hemostatic agent in combination with non- steroidal anti-inflammatory drug |
| WO2012170578A1 (en) * | 2011-06-06 | 2012-12-13 | Oak Crest Institute Of Science | Drug delivery device employing wicking release window |
| RU2740680C2 (ru) | 2011-09-14 | 2021-01-19 | Форсайт Вижн5, Инк. | Глазное вкладочное устройство и способы |
| MX365818B (es) | 2011-11-23 | 2019-05-30 | Therapeuticsmd Inc | Formulaciones y terapias de reemplazo hormonal de combinacion naturales. |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| ES2752028T3 (es) | 2012-10-26 | 2020-04-02 | Forsight Vision5 Inc | Sistema oftálmico para la liberación sostenida del fármaco en el ojo |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| WO2015055789A1 (en) | 2013-10-17 | 2015-04-23 | Bayer Pharma Aktiengesellschaft | INTRAVAGINAL USE OF 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, INTRAVAGINAL RINGS COMPRISING 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, AND USE THEREOF IN CONTRACEPTION |
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| WO2015086489A1 (en) | 2013-12-11 | 2015-06-18 | Merck Sharp & Dohme B.V. | Drug delivery system for delivery of anti-virals |
| US10413504B2 (en) | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
| DE102014004388A1 (de) * | 2014-03-26 | 2015-10-01 | Angela Kayser | Verfahren und System zum intravaginalen Verabreichen von Progesteron |
| MX2016014281A (es) | 2014-05-22 | 2017-02-22 | Therapeuticsmd Inc | Formulaciones y terapias de reemplazo de combinación de hormonas naturales. |
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| FI3294300T3 (fi) | 2015-05-13 | 2025-03-06 | Bayer Oy | Pitkävaikutteinen lääkkeenantolaite implantin tai kierukan muodossa, joka käsittää levonorgestreelia ja etinyyliestradiolia |
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| ES2928873T3 (es) | 2016-03-23 | 2022-11-23 | Univ North Carolina Chapel Hill | Anillos intravaginales geométricamente complejos, sistemas y métodos para hacerlos |
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| EP3435977A4 (en) | 2016-04-01 | 2019-10-16 | Therapeuticsmd, Inc. | PHARMACEUTICAL COMPOSITION OF STEROID HORMONE |
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| DE102017113166A1 (de) | 2017-06-14 | 2018-12-20 | Amw Gmbh | Depotform zur Abgabe eines Östrogen-Wirkstoffs |
| EP4628016A3 (en) | 2017-10-27 | 2025-12-17 | Axena Health, Inc. | Devices, systems, and methods for training pelvic floor muscles |
| CN114727953B (zh) * | 2019-11-12 | 2024-05-14 | 聚合-医药有限公司 | 避孕医疗装置 |
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Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3279996A (en) * | 1962-08-28 | 1966-10-18 | Jr David M Long | Polysiloxane carrier for controlled release of drugs and other agents |
| US3545439A (en) * | 1968-01-04 | 1970-12-08 | Upjohn Co | Medicated devices and methods |
| US3854480A (en) * | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
| CA988849A (en) * | 1969-06-16 | 1976-05-11 | Antonio Scommegna | Anti-fertility device |
| GB1264731A (enExample) * | 1969-11-10 | 1972-02-23 | ||
| US3845761A (en) * | 1970-06-02 | 1974-11-05 | Alza Corp | Intrauterine contraceptive anti-fertility device for the management of reproduction |
| US3920805A (en) * | 1971-12-09 | 1975-11-18 | Upjohn Co | Pharmaceutical devices and method |
| US3851648A (en) * | 1973-10-11 | 1974-12-03 | Mead Johnson & Co | Zero-order release device |
| FR2270899A1 (en) * | 1974-05-16 | 1975-12-12 | Groves Harvey | Vaginal medicator with long medicament-carrying stem - having anchor to correctly position stem |
| DE2445971A1 (de) * | 1974-09-24 | 1976-04-08 | Schering Ag | Arzneimittelwirkstofftraeger ii |
| DE2450107A1 (de) * | 1974-10-18 | 1976-04-29 | Schering Ag | Vaginalring |
| IL48277A (en) * | 1974-10-18 | 1978-03-10 | Schering Ag | Vaginal ring |
| US4155991A (en) * | 1974-10-18 | 1979-05-22 | Schering Aktiengesellschaft | Vaginal ring |
| US4215691A (en) * | 1978-10-11 | 1980-08-05 | Alza Corporation | Vaginal contraceptive system made from block copolymer |
| US4292965A (en) * | 1978-12-29 | 1981-10-06 | The Population Council, Inc. | Intravaginal ring |
-
1980
- 1980-10-28 DE DE19803040978 patent/DE3040978A1/de not_active Withdrawn
-
1981
- 1981-10-22 DD DD81234288A patent/DD201645A5/de not_active IP Right Cessation
- 1981-10-22 AU AU76709/81A patent/AU7670981A/en not_active Abandoned
- 1981-10-22 YU YU02522/81A patent/YU252281A/xx unknown
- 1981-10-23 GR GR66351A patent/GR75367B/el unknown
- 1981-10-24 EP EP81108872A patent/EP0050867B1/en not_active Expired
- 1981-10-24 DE DE8181108872T patent/DE3176606D1/de not_active Expired
- 1981-10-24 AT AT81108872T patent/ATE31875T1/de active
- 1981-10-26 DK DK471481A patent/DK151529C/da not_active IP Right Cessation
- 1981-10-26 JP JP56170262A patent/JPS5799954A/ja active Pending
- 1981-10-27 SU SU813347855A patent/SU1440326A3/ru active
- 1981-10-27 IE IE2503/81A patent/IE54581B1/en not_active IP Right Cessation
- 1981-10-27 CA CA000388832A patent/CA1165239A/en not_active Expired
- 1981-10-27 ES ES527301A patent/ES527301A0/es active Granted
- 1981-10-27 ES ES1981261058U patent/ES261058U/es active Pending
- 1981-10-27 NO NO813625A patent/NO153753C/no unknown
- 1981-10-27 PT PT73886A patent/PT73886B/pt not_active IP Right Cessation
- 1981-10-27 FI FI813360A patent/FI78389C/fi not_active IP Right Cessation
- 1981-10-27 EG EG81625A patent/EG15347A/xx active
- 1981-10-27 HU HU813156A patent/HU183646B/hu unknown
- 1981-10-28 BG BG053982A patent/BG42182A3/xx unknown
- 1981-10-28 RO RO81105663A patent/RO88674A/ro unknown
- 1981-10-28 ZW ZW260/81A patent/ZW26081A1/xx unknown
- 1981-10-28 CS CS817905A patent/CS253564B2/cs unknown
- 1981-10-28 PL PL1981233606A patent/PL127941B1/pl unknown
- 1981-10-28 IL IL64139A patent/IL64139A/xx not_active IP Right Cessation
- 1981-10-28 ZA ZA817477A patent/ZA817477B/xx unknown
-
1987
- 1987-02-13 US US07/014,316 patent/US4822616A/en not_active Expired - Fee Related
-
1990
- 1990-02-19 JP JP1990014821U patent/JPH048893Y2/ja not_active Expired
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 |