HRP20202033T1 - Sastavi koji sadrže bakterijske sojeve - Google Patents
Sastavi koji sadrže bakterijske sojeve Download PDFInfo
- Publication number
- HRP20202033T1 HRP20202033T1 HRP20202033TT HRP20202033T HRP20202033T1 HR P20202033 T1 HRP20202033 T1 HR P20202033T1 HR P20202033T T HRP20202033T T HR P20202033TT HR P20202033 T HRP20202033 T HR P20202033T HR P20202033 T1 HRP20202033 T1 HR P20202033T1
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- Croatia
- Prior art keywords
- composition
- disease
- bacterial strain
- use according
- parkinson
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 22
- 230000001580 bacterial effect Effects 0.000 title claims 14
- 208000018737 Parkinson disease Diseases 0.000 claims 7
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 6
- 208000010877 cognitive disease Diseases 0.000 claims 6
- 230000002265 prevention Effects 0.000 claims 5
- 108020004465 16S ribosomal RNA Proteins 0.000 claims 4
- 208000024827 Alzheimer disease Diseases 0.000 claims 3
- 208000028698 Cognitive impairment Diseases 0.000 claims 3
- 208000011990 Corticobasal Degeneration Diseases 0.000 claims 3
- 206010012289 Dementia Diseases 0.000 claims 3
- 208000023105 Huntington disease Diseases 0.000 claims 3
- 208000024777 Prion disease Diseases 0.000 claims 3
- 241000872832 Roseburia hominis Species 0.000 claims 3
- 241000398180 Roseburia intestinalis Species 0.000 claims 3
- 208000009415 Spinocerebellar Ataxias Diseases 0.000 claims 3
- 208000027061 mild cognitive impairment Diseases 0.000 claims 3
- 208000005264 motor neuron disease Diseases 0.000 claims 3
- 208000001282 primary progressive aphasia Diseases 0.000 claims 3
- 201000002212 progressive supranuclear palsy Diseases 0.000 claims 3
- 208000002320 spinal muscular atrophy Diseases 0.000 claims 3
- 241000894006 Bacteria Species 0.000 claims 2
- 201000006474 Brain Ischemia Diseases 0.000 claims 2
- 206010008120 Cerebral ischaemia Diseases 0.000 claims 2
- 206010034010 Parkinsonism Diseases 0.000 claims 2
- 241000605947 Roseburia Species 0.000 claims 2
- 241000872831 Roseburia faecis Species 0.000 claims 2
- 206010008118 cerebral infarction Diseases 0.000 claims 2
- 230000002792 vascular Effects 0.000 claims 2
- 102000014461 Ataxins Human genes 0.000 claims 1
- 108010078286 Ataxins Proteins 0.000 claims 1
- 206010008025 Cerebellar ataxia Diseases 0.000 claims 1
- 201000011240 Frontotemporal dementia Diseases 0.000 claims 1
- 208000016988 Hemorrhagic Stroke Diseases 0.000 claims 1
- 208000032382 Ischaemic stroke Diseases 0.000 claims 1
- 208000009829 Lewy Body Disease Diseases 0.000 claims 1
- 201000002832 Lewy body dementia Diseases 0.000 claims 1
- 208000026072 Motor neurone disease Diseases 0.000 claims 1
- 208000027089 Parkinsonian disease Diseases 0.000 claims 1
- 208000006011 Stroke Diseases 0.000 claims 1
- 201000004810 Vascular dementia Diseases 0.000 claims 1
- 201000004562 autosomal dominant cerebellar ataxia Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 208000020658 intracerebral hemorrhage Diseases 0.000 claims 1
- 210000004558 lewy body Anatomy 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 201000003077 normal pressure hydrocephalus Diseases 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 208000014670 posterior cortical atrophy Diseases 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Claims (15)
1. Sastav koja sadrži soj bakterija roda Roseburia, za upotrebu u postupku liječenja ili prevencije Parkinsonove bolesti, koja uključuje progresivnu supranuklearnu paralizu, progresivnu supranuklearnu paralizu, Steele-Richardson-Olszewski sindrom, hidrocefalus normalnog pritiska, vaskularni ili arteriosklerotski parkinsonizam i parkinsonizam izazvan lijekovima; Alzheimerove bolesti, koja uključuje Bensonov sindrom; Hantingtonove bolesti; amiotrofične lateralne skleroze; Lu Gerigove bolesti; bolesti motornih neurona; prionske bolesti; spinocerebelarne ataksije; spinalne mišićne atrofije; demencije, koja uključuje Levijevo tijelo, vaskularnu i frontotemporalnu demenciju; primarne progresivne afazije; blagog kognitivnog oštećenja; kognitivnog oštećenja povezanog sa HIV-om; ili kortikobazalne degeneracije.
2. Sastav za upotrebu prema patentnom zahtjevu 1, pri čemu je sastav za upotrebu u postupku liječenja ili prevencije Parkinsonove bolesti.
3. Sastav za upotrebu prema bilo kojem od patentnih zahtjeva 1 ili 2, gdje se (a) Parkinsonova bolest; Alzheimerova bolest; Hantingtonova bolest; amiotrofična lateralna skleroza; Lu Gerigova bolest; bolest motornih neurona; prionska bolest; spinocerebelarna ataksija; spinalna mišićna atrofija; demencija; primarna progresivna afazija; blago kognitivno oštećenje; kognitivno oštećenje povezano sa HIV-om; ili kortikobazalna degeneracija; rano javlјa; i/ili u kome (b) je sastav za upotrebu u postupku sprječavanja ili odlaganja početka ili progresije Parkinsonove bolesti; Alzheimerove bolesti, Hantingtonove bolesti; amiotrofične lateralne skleroze; Lu Gerigove bolesti; bolesti motornih neurona; prionske bolesti; spinocerebelarne ataksije; spinalne mišićne atrofije; demencije; primarne progresivne afazije; blagog kognitivnog oštećenja; kognitivnog oštećenja povezanog sa HIV-om; ili kortikobazalne degeneracije.
4. Sastav koji sadrži soj bakterija roda Roseburia, za upotrebu u postupku liječenja moždanog udara, poput cerebralne ishemije, fokalne cerebralne ishemije, ishemijskog moždanog udara ili hemoragijskog moždanog udara.
5. Sastav za upotrebu prema bilo kojem od prethodnih patentnih zahtjeva, u kome je bakterijski soj Roseburia hominis, opcionalno pri čemu bakterijski soj ima sekvencu 16s rRNK koja je najmanje 96%, 97%, 98%, 99%, 99,5% ili 99,9% identična SEQ ID NO:3, ili gdje bakterijski soj ima 16s rRNK sekvencu koja je predstavlјena u SEQ ID NO:3.
6. Sastav za upotrebu prema patentnom zahtjevu 1, pri čemu sastav sadrži bakterijski soj vrste Roseburia hominis, za upotrebu u postupku liječenja ili prevencije Parkinsonove bolesti.
7. Sastav za upotrebu prema bilo kojem od patentnih zahtjeva 5-6, pri čemu je bakterijski soj Roseburia hominis deponiran pod pristupnim brojem NCIMB 42383.
8. Sastav za upotrebu prema patentnim zahtjevima 1-4, pri čemu je bakterijski soj vrste Roseburia intestinalis, opcionalno pri čemu bakterijski soj ima sekvencu 16s rRNK koja je najmanje 99%, 99,5% ili 99,9% identična SEQ ID NO:5.
9. Sastav za upotrebu prema patentnim zahtjevima 1-3, pri čemu sadrži bakterijski soj vrste Roseburia intestinalis, za upotrebu u postupku liječenja ili prevencije Parkinsonove bolesti.
10. Sastav za upotrebu prema bilo kojem od patentnih zahtjeva 8 ili 9, pri čemu je bakterijski soj Roseburia intestinalis deponiran pod pristupnim brojem NCIMB 43043.
11. Sastav za upotrebu prema patentnim zahtjevima 1-4, pri čemu je bakterijski soj vrste Roseburia faecis, opcionalno pri čemu bakterijski soj ima sekvencu 16s rRNK koja je najmanje 99%, 99,5% ili 99,9% identična SEQ ID NO:6.
12. Sastav za upotrebu prema patentnim zahtjevima 1-3, pri čemu sastav sadrži bakterijski soj vrste Roseburia faecis, za upotrebu u postupku liječenja ili prevencije Parkinsonove bolesti.
13. Sastav za upotrebu prema bilo kojem od prethodnih patentnih zahtjeva, pri čemu je sastav za oralnu primjenu; i ili gdje sastav sadrži jedan ili više farmaceutski prihvatljivih pomoćnih tvari ili nosača.
14. Sastav za upotrebu prema bilo kojem od prethodnih patentnih zahtjeva, pri čemu je soj bakterija liofiliziran.
15. Prehrambeni proizvod koji sadrži sastav iz bilo kojeg prethodnog patentnih zahtjeva, za upotrebu u skladu sa bilo kojim od prethodnih patentnih zahtjeva.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1709466.5A GB201709466D0 (en) | 2017-06-14 | 2017-06-14 | Compositions comprising bacterial strains |
GBGB1709533.2A GB201709533D0 (en) | 2017-06-15 | 2017-06-15 | Compositions comprising bacterial strains |
PCT/EP2018/065808 WO2018229188A1 (en) | 2017-06-14 | 2018-06-14 | Compositions comprising bacterial strains |
EP18731444.8A EP3638271B1 (en) | 2017-06-14 | 2018-06-14 | Compositions comprising bacterial strains |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20202033T1 true HRP20202033T1 (hr) | 2021-02-19 |
Family
ID=62620889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20202033TT HRP20202033T1 (hr) | 2017-06-14 | 2020-12-18 | Sastavi koji sadrže bakterijske sojeve |
Country Status (16)
Country | Link |
---|---|
US (2) | US11123379B2 (hr) |
EP (1) | EP3638271B1 (hr) |
JP (1) | JP6884889B2 (hr) |
CY (1) | CY1123890T1 (hr) |
DK (1) | DK3638271T3 (hr) |
ES (1) | ES2841902T3 (hr) |
HR (1) | HRP20202033T1 (hr) |
HU (1) | HUE052319T2 (hr) |
LT (1) | LT3638271T (hr) |
MA (1) | MA49373B1 (hr) |
MD (1) | MD3638271T2 (hr) |
PT (1) | PT3638271T (hr) |
RS (1) | RS61210B1 (hr) |
SI (1) | SI3638271T1 (hr) |
TW (1) | TW201919670A (hr) |
WO (1) | WO2018229188A1 (hr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2841902T3 (es) | 2017-06-14 | 2021-07-12 | 4D Pharma Res Ltd | Composiciones que comprenden cepas bacterianas |
CN112351786A (zh) * | 2018-06-14 | 2021-02-09 | 4D制药研究有限公司 | 包含细菌菌株的组合物 |
CN116211898A (zh) * | 2020-11-26 | 2023-06-06 | 内蒙古伊利实业集团股份有限公司 | 调节睡眠的乳双歧杆菌bl-99及其应用 |
NL2032642B1 (en) * | 2022-07-29 | 2024-02-06 | Academisch Ziekenhuis Leiden | Improvement of muscle mass and strength |
KR102547039B1 (ko) * | 2023-01-10 | 2023-06-26 | 주식회사 바이오뱅크힐링 | 로제부리아 파에시스를 유효성분으로 포함하는 퇴행성 뇌질환 예방 또는 치료용 조성물 |
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IT201600091033A1 (it) | 2016-09-08 | 2018-03-08 | Bioimmunizer Sagl | Ceppi di batteri probiotici appartenenti al genere Bifidobacterium e loro estratti di cellule probiotiche (ECP) aventi proprietà immunostimolanti. |
GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
WO2018112363A1 (en) | 2016-12-16 | 2018-06-21 | Evelo Biosciences, Inc. | Methods of treating cancer using parabacteroides |
WO2018112365A2 (en) | 2016-12-16 | 2018-06-21 | Evelo Biosciences, Inc. | Methods of treating colorectal cancer and melanoma using parabacteroides goldsteinii |
MA41708A (fr) | 2017-05-24 | 2020-04-08 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
ES2841902T3 (es) | 2017-06-14 | 2021-07-12 | 4D Pharma Res Ltd | Composiciones que comprenden cepas bacterianas |
BR112019028301A2 (pt) | 2017-07-05 | 2020-07-14 | Evelo Biosciences, Inc. | composições e métodos para tratar câncer com o uso de bifidobacterium animalis ssp. lactis |
-
2018
- 2018-06-14 ES ES18731444T patent/ES2841902T3/es active Active
- 2018-06-14 MA MA49373A patent/MA49373B1/fr unknown
- 2018-06-14 WO PCT/EP2018/065808 patent/WO2018229188A1/en active Search and Examination
- 2018-06-14 PT PT187314448T patent/PT3638271T/pt unknown
- 2018-06-14 RS RS20201540A patent/RS61210B1/sr unknown
- 2018-06-14 SI SI201830151T patent/SI3638271T1/sl unknown
- 2018-06-14 LT LTEP18731444.8T patent/LT3638271T/lt unknown
- 2018-06-14 MD MDE20200411T patent/MD3638271T2/ro unknown
- 2018-06-14 EP EP18731444.8A patent/EP3638271B1/en active Active
- 2018-06-14 JP JP2019568210A patent/JP6884889B2/ja active Active
- 2018-06-14 DK DK18731444.8T patent/DK3638271T3/da active
- 2018-06-14 HU HUE18731444A patent/HUE052319T2/hu unknown
- 2018-06-14 TW TW107120604A patent/TW201919670A/zh unknown
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2019
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2020
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- 2020-12-30 CY CY20201101232T patent/CY1123890T1/el unknown
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2021
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LT3638271T (lt) | 2021-01-11 |
MD3638271T2 (ro) | 2021-03-31 |
PT3638271T (pt) | 2021-01-05 |
MA49373B1 (fr) | 2021-02-26 |
CY1123890T1 (el) | 2022-03-24 |
US20220096565A1 (en) | 2022-03-31 |
RS61210B1 (sr) | 2021-01-29 |
EP3638271B1 (en) | 2020-10-14 |
WO2018229188A1 (en) | 2018-12-20 |
MA49373A (fr) | 2020-04-22 |
HUE052319T2 (hu) | 2021-04-28 |
EP3638271A1 (en) | 2020-04-22 |
US20200179459A1 (en) | 2020-06-11 |
SI3638271T1 (sl) | 2021-01-29 |
ES2841902T3 (es) | 2021-07-12 |
JP6884889B2 (ja) | 2021-06-09 |
JP2020523341A (ja) | 2020-08-06 |
US11123379B2 (en) | 2021-09-21 |
TW201919670A (zh) | 2019-06-01 |
DK3638271T3 (da) | 2020-12-07 |
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