HRP20191854T1 - Orodisperzibilni dezmopresin za povećanje početnog razdoblja sna neometanog s nokturijom - Google Patents
Orodisperzibilni dezmopresin za povećanje početnog razdoblja sna neometanog s nokturijom Download PDFInfo
- Publication number
- HRP20191854T1 HRP20191854T1 HRP20191854TT HRP20191854T HRP20191854T1 HR P20191854 T1 HRP20191854 T1 HR P20191854T1 HR P20191854T T HRP20191854T T HR P20191854TT HR P20191854 T HRP20191854 T HR P20191854T HR P20191854 T1 HRP20191854 T1 HR P20191854T1
- Authority
- HR
- Croatia
- Prior art keywords
- desmopressin
- preparation
- use according
- dose
- increase
- Prior art date
Links
- 108010000437 Deamino Arginine Vasopressin Proteins 0.000 title claims 11
- 229960004281 desmopressin Drugs 0.000 title claims 10
- NFLWUMRGJYTJIN-NXBWRCJVSA-N desmopressin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSCCC(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O)=O)CCC(=O)N)C1=CC=CC=C1 NFLWUMRGJYTJIN-NXBWRCJVSA-N 0.000 title claims 10
- 206010029446 nocturia Diseases 0.000 title claims 5
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 3
- 239000012458 free base Substances 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- FIEYHAAMDAPVCH-UHFFFAOYSA-N 2-methyl-1h-quinazolin-4-one Chemical compound C1=CC=C2NC(C)=NC(=O)C2=C1 FIEYHAAMDAPVCH-UHFFFAOYSA-N 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- 108010010803 Gelatin Proteins 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- 159000000021 acetate salts Chemical class 0.000 claims 1
- 239000002585 base Substances 0.000 claims 1
- 235000015165 citric acid Nutrition 0.000 claims 1
- 229960002845 desmopressin acetate Drugs 0.000 claims 1
- 229920000159 gelatin Polymers 0.000 claims 1
- 239000008273 gelatin Substances 0.000 claims 1
- 235000019322 gelatine Nutrition 0.000 claims 1
- 235000011852 gelatine desserts Nutrition 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 239000000594 mannitol Substances 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Claims (11)
1. Pripravak koji sadrži dezmopresin za uporabu u liječenju nokturije ili noćne poliurije za povećanje početnog razdoblja nesmetanog spavanja kod ženskog pacijenta kojem je potreban, naznačen time da pripravak sadrži orodisperzibilnu dozu od 25 mikrograma dezmopresina pri čemu se doza mjeri kao slobodna baza dezmopresina i koja se daje pacijentu prije spavanja.
2. Pripravak koji sadrži dezmopresin za uporabu u liječenju nokturije ili noćne poliurije za povećanje početnog razdoblja nesmetanog spavanja kod muškog pacijenta, naznačen time da pripravak sadrži orodisperzibilnu dozu od 50 mikrograma dezmopresina pri čemu se doza mjeri kao slobodna baza dezmopresina i koja se daje pacijentu prije spavanja.
3. Pripravak za uporabu prema patentnom zahtjevu 1, naznačen time da je povećanje u početnom periodu nesmetanog spavanja od 37 do 114 minuta, poželjno od 76 do 114 minuta.
4. Pripravak za uporabu prema patentnom zahtjevu 1 ili 3, naznačen time da se doza uzima jednom dnevno.
5. Pripravak za uporabu prema bilo kojem od patentnih zahtjeva 1 do 4, naznačen time da se doza dezmopresin baze daje u obliku acetatne soli dezmopresina.
6. Pripravak za uporabu prema bilo kojem od zahtjeva 1 do 5, naznačen time da je orodisperzibilna doza dezmopresina tableta koja se brzo otapa, a sadrži dezmopresin acetat, želatinu, manitol i limunsku kiselinu.
7. Pripravak za upotrebu prema bilo kojem od zahtjeva 1 do 6, naznačen time da razdoblje liječenja iznosi 28 dana.
8. Pripravak za uporabu prema bilo kojem od patentnom zahtjevu 1 i 4 do 7, naznačen time da je ženski pacijent stariji od 50 godina.
9. Pripravak za uporabu prema patentnom zahtjevu 8, naznačen time da porast početnog nesmetanog spavanja iznosi od 77 do 115 minuta.
10. Pripravak za upotrebu prema bilo kojem od zahtjeva 1 do i 4 do 7, naznačen time da je ženski pacijent stariji od 65 godina.
11. Pripravak za uporabu u skladu s patentnim zahtjevom 10, naznačen time da se porast početnog nesmetanog spavanja kreće od 90 do 136 minuta.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5512008P | 2008-05-21 | 2008-05-21 | |
EP17171155.9A EP3225250B1 (en) | 2008-05-21 | 2009-05-21 | Orodispersible desmopressin for increasing initial period of sleep undisturbed by nocturia |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20191854T1 true HRP20191854T1 (hr) | 2019-12-27 |
Family
ID=41100519
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20161066TT HRP20161066T1 (hr) | 2008-05-21 | 2016-08-22 | Orodisperzibilni dezmopresin za povećanje početnog razdoblja sna neometanog s nokturijom |
HRP20180774TT HRP20180774T1 (hr) | 2008-05-21 | 2018-05-17 | Orodisperzibilni dezmopresin za povećanje početnog razdoblja sna neometanog s nokturijom |
HRP20190114TT HRP20190114T1 (hr) | 2008-05-21 | 2019-01-18 | Orodisperzibilni dezmopresin za povećanje početnog razdoblja sna neometanog s nokturijom |
HRP20191854TT HRP20191854T1 (hr) | 2008-05-21 | 2019-10-14 | Orodisperzibilni dezmopresin za povećanje početnog razdoblja sna neometanog s nokturijom |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20161066TT HRP20161066T1 (hr) | 2008-05-21 | 2016-08-22 | Orodisperzibilni dezmopresin za povećanje početnog razdoblja sna neometanog s nokturijom |
HRP20180774TT HRP20180774T1 (hr) | 2008-05-21 | 2018-05-17 | Orodisperzibilni dezmopresin za povećanje početnog razdoblja sna neometanog s nokturijom |
HRP20190114TT HRP20190114T1 (hr) | 2008-05-21 | 2019-01-18 | Orodisperzibilni dezmopresin za povećanje početnog razdoblja sna neometanog s nokturijom |
Country Status (16)
Country | Link |
---|---|
US (2) | US9974826B2 (hr) |
EP (5) | EP3225250B1 (hr) |
JP (5) | JP5767103B2 (hr) |
CA (1) | CA2724653A1 (hr) |
DK (5) | DK3225250T3 (hr) |
ES (5) | ES2677548T3 (hr) |
HR (4) | HRP20161066T1 (hr) |
HU (5) | HUE041370T2 (hr) |
LT (5) | LT3225249T (hr) |
LU (1) | LUC00015I2 (hr) |
NO (3) | NO3085381T3 (hr) |
PL (5) | PL2296686T5 (hr) |
PT (5) | PT2712622T (hr) |
SI (4) | SI3085381T1 (hr) |
TR (2) | TR201819189T4 (hr) |
WO (1) | WO2009143356A1 (hr) |
Families Citing this family (7)
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US20100286045A1 (en) * | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
LT3225249T (lt) * | 2008-05-21 | 2019-01-10 | Ferring B.V. | Burnoje disperguojamas desmopresinas, skirtas pirminio miego periodo, nepertraukiamo nikturija, pailginimui |
US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
WO2015063602A1 (en) * | 2013-10-29 | 2015-05-07 | Ferring B.V. | Desmopressin and blood glucose |
US20210393562A1 (en) * | 2018-10-17 | 2021-12-23 | Nippon Chemiphar Co., Ltd. | Therapeutic or prophylactic agent for nocturnal polyuria |
EP4137206A1 (en) * | 2020-04-14 | 2023-02-22 | Nippon Chemiphar Co., Ltd. | Agent for improving quality of sleep |
US11672761B2 (en) | 2020-11-16 | 2023-06-13 | Orcosa Inc. | Rapidly infusing platform and compositions for therapeutic treatment in humans |
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