MX2007013021A - Derivados de benzofuranil-alcanamina y usos de los mismos como agonistas de 5-ht2c. - Google Patents
Derivados de benzofuranil-alcanamina y usos de los mismos como agonistas de 5-ht2c.Info
- Publication number
- MX2007013021A MX2007013021A MX2007013021A MX2007013021A MX2007013021A MX 2007013021 A MX2007013021 A MX 2007013021A MX 2007013021 A MX2007013021 A MX 2007013021A MX 2007013021 A MX2007013021 A MX 2007013021A MX 2007013021 A MX2007013021 A MX 2007013021A
- Authority
- MX
- Mexico
- Prior art keywords
- sup
- benzofuranyl
- compounds
- ht2c agonists
- agonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se proporciona un compuesto de la formula I o sales farmaceuticamente aceptables de los mismos; en donde cada uno de R1, R1??, R2, R3, R4, n y Ar son como se definen en la descripcion que son agonistas o agonistas parciales del subtipo 2C de receptores cerebrales de serotonina. Los compuestos, y composiciones que contienen los compuestos, se pueden usar para tratar una variedad de trastornos del sistema nervioso central tal como esquizofrenia.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67412905P | 2005-04-22 | 2005-04-22 | |
PCT/US2006/015193 WO2006116151A1 (en) | 2005-04-22 | 2006-04-21 | Benzofuranyl alkanamine derivatives and uses thereof as 5-ht2c agonists |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2007013021A true MX2007013021A (es) | 2008-01-11 |
Family
ID=36699265
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2007013021A MX2007013021A (es) | 2005-04-22 | 2006-04-21 | Derivados de benzofuranil-alcanamina y usos de los mismos como agonistas de 5-ht2c. |
Country Status (9)
Country | Link |
---|---|
US (2) | US7368477B2 (es) |
EP (1) | EP1871358A1 (es) |
JP (1) | JP2008538573A (es) |
CN (1) | CN101203218A (es) |
AU (1) | AU2006239922A1 (es) |
BR (1) | BRPI0610036A2 (es) |
CA (1) | CA2605554A1 (es) |
MX (1) | MX2007013021A (es) |
WO (1) | WO2006116151A1 (es) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
GT200500297A (es) * | 2004-10-21 | 2006-10-27 | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
GT200500296A (es) * | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
US7396857B2 (en) * | 2005-04-22 | 2008-07-08 | Wyeth | Therapeutic combinations for the treatment or prevention of depression |
CN101203218A (zh) * | 2005-04-22 | 2008-06-18 | 惠氏公司 | 苯并呋喃基链烷胺衍生物和其作为5-ht2c激动剂的用途 |
WO2006116136A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Dihydrobenzofuran derivatives and uses thereof |
US20060258713A1 (en) * | 2005-04-22 | 2006-11-16 | Wyeth | Treatment of pain |
MX2007013151A (es) * | 2005-04-22 | 2008-01-16 | Wyeth Corp | Derivados de benzodioxano y benzodioxolano y usos de los mismos. |
TW200718692A (en) * | 2005-04-22 | 2007-05-16 | Wyeth Corp | Dihydrobenzofuran derivatives and uses thereof |
CN101203216A (zh) * | 2005-04-22 | 2008-06-18 | 惠氏公司 | 二氢苯并呋喃衍生物及其用途 |
CN101198323A (zh) * | 2005-04-22 | 2008-06-11 | 惠氏公司 | 用于治疗或预防精神障碍的治疗组合 |
EP1874756A1 (en) * | 2005-04-22 | 2008-01-09 | Wyeth | Chromane and chromene derivatives and uses thereof |
MX2007013064A (es) * | 2005-04-24 | 2008-01-16 | Wyeth Corp | Metodo para modular la funcion de la vejiga. |
CN101448492A (zh) * | 2006-03-24 | 2009-06-03 | 惠氏公司 | 治疗认知障碍和其它障碍的方法 |
EP2018863B9 (en) | 2006-05-16 | 2015-02-18 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound and use thereof |
KR101522747B1 (ko) | 2007-08-06 | 2015-05-26 | 알레간 인코포레이티드 | 데스모프레신 약물 전달을 위한 방법 및 장치 |
US20100266504A1 (en) | 2007-11-15 | 2010-10-21 | Takahiro Matsumoto | Condensed pyridine derivative and use thereof |
EP2116618A1 (en) | 2008-05-09 | 2009-11-11 | Agency for Science, Technology And Research | Diagnosis and treatment of Kawasaki disease |
PT2712622T (pt) | 2008-05-21 | 2016-10-13 | Ferring Bv | Desmopressina orodispersível para aumentar o período inicial de sono tranquilo |
US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
US20130267500A1 (en) | 2010-09-01 | 2013-10-10 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level |
CN102267989B (zh) * | 2011-06-03 | 2014-06-11 | 浙江工业大学 | 一种2-甲基苯并呋喃类化合物及其制备与应用 |
WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
JPWO2019131902A1 (ja) | 2017-12-27 | 2020-12-10 | 武田薬品工業株式会社 | 腹圧性尿失禁および便失禁の治療薬 |
WO2020072675A1 (en) | 2018-10-02 | 2020-04-09 | Northwestern University | Beta-carbolines as positive allosteric modulators of the human serotonin receptor 2c (5-ht2c) |
EP3878447A1 (en) * | 2020-03-11 | 2021-09-15 | InterAx Biotech AG | Beta adrenergic receptor antagonists |
KR20230066313A (ko) | 2020-06-08 | 2023-05-15 | 탁토젠 인크 | 정신 장애 또는 정신적 증강에 유리한 벤조푸란 조성물 |
CN116253704A (zh) * | 2021-12-10 | 2023-06-13 | 中国科学院昆明植物研究所 | Paeoveitol D衍生物及其药物组合物和其制备方法与其应用 |
WO2024108179A2 (en) * | 2022-11-18 | 2024-05-23 | Tactogen Inc | 2-ethylamine substituted benzofuran and benzothiophene compositions for mental disorders or enhancement |
Family Cites Families (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2554736A (en) * | 1951-05-29 | Tertiary aminoalkyl-iminodibenzyls | ||
GB1422263A (en) | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
US4314081A (en) | 1974-01-10 | 1982-02-02 | Eli Lilly And Company | Arloxyphenylpropylamines |
NL7503310A (nl) | 1975-03-20 | 1976-09-22 | Philips Nv | Verbindingen met antidepressieve werking. |
GB1526331A (en) | 1976-01-14 | 1978-09-27 | Kefalas As | Phthalanes |
US4210754A (en) * | 1977-02-01 | 1980-07-01 | Hoffmann-La Roche Inc. | Morpholino containing benzamides |
IL56369A (en) * | 1978-01-20 | 1984-05-31 | Erba Farmitalia | Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them |
US4536518A (en) | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
FR2508035A1 (fr) * | 1981-06-23 | 1982-12-24 | Fabre Sa Pierre | Derives d'aryl-1-aminomethyl-2 cyclopropanes carboxamides (z), leur preparation et leur application en tant que medicaments utiles dans le traitement des troubles du systeme nerveux central |
US4535186A (en) * | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
GB8814057D0 (en) * | 1988-06-14 | 1988-07-20 | Lundbeck & Co As H | New enantiomers & their isolation |
DE4200259A1 (de) * | 1992-01-08 | 1993-07-15 | Asta Medica Ag | Neue 1,2,4-triaminobenzol-derivate und verfahren zu deren herstellung |
US6765008B1 (en) * | 1992-12-17 | 2004-07-20 | Pfizer Inc | Pyrrolopyrimidines as CRF antagonists |
TW370529B (en) * | 1992-12-17 | 1999-09-21 | Pfizer | Pyrazolopyrimidines |
WO1994013643A1 (en) * | 1992-12-17 | 1994-06-23 | Pfizer Inc. | Pyrazoles and pyrazolopyrimidines having crf antagonist activity |
SG47711A1 (en) * | 1993-06-28 | 1998-04-17 | American Home Prod | New treatments using phenehylamine derivatives |
US5705646A (en) * | 1993-09-30 | 1998-01-06 | Pfizer Inc. | Substituted pyrazoles as CRF antagonists |
US5668145A (en) * | 1993-11-12 | 1997-09-16 | Pfizer Inc. | Amino-substituted pyrazoles having CRF antagonistic activity |
WO1995034540A1 (en) * | 1994-06-15 | 1995-12-21 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic derivatives useful as vasopressin or oxytocin modulators |
US5565483A (en) * | 1995-06-07 | 1996-10-15 | Bristol-Myers Squibb Company | 3-substituted oxindole derivatives as potassium channel modulators |
TW359669B (en) * | 1995-12-15 | 1999-06-01 | Otsuka Pharma Co Ltd | Benzazepine derivatives |
US6274171B1 (en) * | 1996-03-25 | 2001-08-14 | American Home Products Corporation | Extended release formulation of venlafaxine hydrochloride |
US6194407B1 (en) * | 1997-07-30 | 2001-02-27 | American Home Products Corporation | Tricyclic pyrido vasopressin agonists |
US6090803A (en) * | 1998-07-24 | 2000-07-18 | American Home Products Corporation | Tricyclic vasopressin agonists |
US6403102B1 (en) * | 1998-10-29 | 2002-06-11 | Connaught Laboratories Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
US7045545B1 (en) * | 1999-01-27 | 2006-05-16 | Eli Lilly And Company | Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists |
EP1149085A1 (en) * | 1999-01-27 | 2001-10-31 | Eli Lilly And Company | Aminoalkylbenzofurans as serotonin (5-ht(2c)) agonists |
ES2203498T3 (es) * | 1999-07-29 | 2004-04-16 | Eli Lilly And Company | Benzofurilpiperazinas: agonistas de receptor 5-ht2c de la serotonina. |
AU2002338333A1 (en) * | 2001-04-04 | 2002-10-21 | Wyeth | Methods for treating hyperactive gastric motility |
US20040235856A1 (en) * | 2003-04-25 | 2004-11-25 | Pfizer Inc | Treatment of incontinence |
US7728155B2 (en) * | 2003-10-24 | 2010-06-01 | Wyeth Llc | Dihydrobenzofuranyl alkanamines and methods for using same as cns agents |
US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
WO2006000902A1 (en) | 2004-06-25 | 2006-01-05 | Pfizer Products Inc. | Dihydrobenzofuran compounds and uses thereof |
GT200500297A (es) * | 2004-10-21 | 2006-10-27 | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
GT200500296A (es) * | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
CN101203216A (zh) * | 2005-04-22 | 2008-06-18 | 惠氏公司 | 二氢苯并呋喃衍生物及其用途 |
US20060258713A1 (en) * | 2005-04-22 | 2006-11-16 | Wyeth | Treatment of pain |
CN101203218A (zh) | 2005-04-22 | 2008-06-18 | 惠氏公司 | 苯并呋喃基链烷胺衍生物和其作为5-ht2c激动剂的用途 |
EP1874756A1 (en) * | 2005-04-22 | 2008-01-09 | Wyeth | Chromane and chromene derivatives and uses thereof |
WO2006116136A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Dihydrobenzofuran derivatives and uses thereof |
MX2007013151A (es) * | 2005-04-22 | 2008-01-16 | Wyeth Corp | Derivados de benzodioxano y benzodioxolano y usos de los mismos. |
CN101163689A (zh) * | 2005-04-22 | 2008-04-16 | 惠氏公司 | {[(2r)-7-(2,6-二氯苯基)-5-氟-2,3-二氢-1-苯并呋喃-2-基]甲基}胺盐酸盐的晶形 |
TW200718692A (en) * | 2005-04-22 | 2007-05-16 | Wyeth Corp | Dihydrobenzofuran derivatives and uses thereof |
BRPI0610509A2 (pt) * | 2005-04-22 | 2010-06-29 | Wyeth Corp | tratamento de dependência a drogas |
CN101198323A (zh) * | 2005-04-22 | 2008-06-11 | 惠氏公司 | 用于治疗或预防精神障碍的治疗组合 |
US7396857B2 (en) * | 2005-04-22 | 2008-07-08 | Wyeth | Therapeutic combinations for the treatment or prevention of depression |
MX2007013064A (es) * | 2005-04-24 | 2008-01-16 | Wyeth Corp | Metodo para modular la funcion de la vejiga. |
-
2006
- 2006-04-21 CN CNA2006800225704A patent/CN101203218A/zh active Pending
- 2006-04-21 AU AU2006239922A patent/AU2006239922A1/en not_active Abandoned
- 2006-04-21 MX MX2007013021A patent/MX2007013021A/es unknown
- 2006-04-21 JP JP2008507945A patent/JP2008538573A/ja active Pending
- 2006-04-21 BR BRPI0610036-8A patent/BRPI0610036A2/pt not_active Application Discontinuation
- 2006-04-21 WO PCT/US2006/015193 patent/WO2006116151A1/en active Application Filing
- 2006-04-21 US US11/408,319 patent/US7368477B2/en not_active Expired - Fee Related
- 2006-04-21 CA CA002605554A patent/CA2605554A1/en not_active Abandoned
- 2006-04-21 EP EP06751045A patent/EP1871358A1/en not_active Withdrawn
-
2008
- 2008-04-18 US US12/105,804 patent/US20080200541A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN101203218A (zh) | 2008-06-18 |
CA2605554A1 (en) | 2006-11-02 |
WO2006116151A1 (en) | 2006-11-02 |
AU2006239922A1 (en) | 2006-11-02 |
JP2008538573A (ja) | 2008-10-30 |
US7368477B2 (en) | 2008-05-06 |
US20060247276A1 (en) | 2006-11-02 |
US20080200541A1 (en) | 2008-08-21 |
EP1871358A1 (en) | 2008-01-02 |
BRPI0610036A2 (pt) | 2010-05-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2007013021A (es) | Derivados de benzofuranil-alcanamina y usos de los mismos como agonistas de 5-ht2c. | |
TW200720266A (en) | Benzodioxane and benzodioxolan derivatives and uses thereof | |
TW200716595A (en) | Chromane and chromene derivatives and uses thereof | |
MX2007012883A (es) | Derivados de dihidrobenzofurano y usos de los mismos. | |
NO20062139L (no) | Dihydrobenzofuranyl-alkanaminderivater som 5HT2C-agonister | |
WO2006050007A3 (en) | Substituted indolizines and derivatives as cns agents | |
MX2007012936A (es) | Derivados de dihidrobenzofurano y usos de los mismos. | |
MX2007013065A (es) | Derivados de dihidrobenzofurano y usos de los mismos. | |
MY133238A (en) | Monoamine reuptake inhibitors for treatment for cns disorders | |
WO2007140439A3 (en) | Compounds as cannabinoid receptor ligands and uses thereof | |
MX2009011205A (es) | Derivados de 2-iminoisotiazol como ligandos del receptor canabinoide. | |
MXPA06014721A (es) | Derivados de alquinilo como moduladores de los receptores de glutamato metabotropico. | |
CA2387517A1 (en) | Novel biaryl ether derivatives useful as monoamine reuptake inhibitors | |
MX2007004699A (es) | Derivados de indol y bencimidazol. | |
BRPI0607532A2 (pt) | derivados de alcanamina de diidrobenzofuranila como agonistas de 5ht2c | |
TW200600506A (en) | Substituted morpholine compounds for the treatment of central nervous system disorders | |
MX2010001486A (es) | Derivados de tetrahidropiridin carboxamida como antagonistas de trpvl. | |
BRPI0415769A (pt) | alcanaminas de diidrobenzofuranila e composições farmacêuticas contendo-as | |
PL1831152T3 (pl) | Pochodne tetraliny i indanu oraz ich zastosowanie jako antagonistów 5-HT | |
WO2008020306A3 (en) | Isoindole derivatives | |
TW200800962A (en) | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | |
MX2009012374A (es) | Compuestos novedosos como ligandos del receptor de canabinoides. | |
MY140835A (en) | Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists | |
SE0401465D0 (sv) | New substituted piperdines as modulators of dopamine neurotransmission | |
WO2008052088A8 (en) | Chromane derivatives, synthesis thereof, and intermediates thereto |