GT200500296A - Sintesis asimetrica de derivados del dehidrobenzofurano - Google Patents

Sintesis asimetrica de derivados del dehidrobenzofurano

Info

Publication number
GT200500296A
GT200500296A GT200500296A GT200500296A GT200500296A GT 200500296 A GT200500296 A GT 200500296A GT 200500296 A GT200500296 A GT 200500296A GT 200500296 A GT200500296 A GT 200500296A GT 200500296 A GT200500296 A GT 200500296A
Authority
GT
Guatemala
Prior art keywords
derivatives
dehydrobenzofuran
asymmetric synthesis
asymmetric
synthesis
Prior art date
Application number
GT200500296A
Other languages
English (en)
Inventor
Dahui Zhou
Gary Paul Stack
Alexander V Gontcharov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200500296A publication Critical patent/GT200500296A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Abstract

ESTA INVENCION SE REFIERE A UN PROCESO PARA LA PREPARACION DE DERIVADOS DE BENZOFURANO. EN ALGUNOS ASPECTOS, ESTOS COMPUESTOS SON DE LA FORMULA I, DONDE R1, R2, R3 Y R 4 SON DEFINIDOS.
GT200500296A 2004-10-21 2005-10-19 Sintesis asimetrica de derivados del dehidrobenzofurano GT200500296A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62102304P 2004-10-21 2004-10-21

Publications (1)

Publication Number Publication Date
GT200500296A true GT200500296A (es) 2006-10-02

Family

ID=35965910

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200500296A GT200500296A (es) 2004-10-21 2005-10-19 Sintesis asimetrica de derivados del dehidrobenzofurano

Country Status (14)

Country Link
US (1) US20060089405A1 (es)
EP (1) EP1802598A2 (es)
JP (1) JP2008517929A (es)
CN (1) CN101107238A (es)
AR (1) AR053980A1 (es)
AU (1) AU2005299757A1 (es)
BR (1) BRPI0516236A (es)
CA (1) CA2584775A1 (es)
GT (1) GT200500296A (es)
MX (1) MX2007004637A (es)
PA (1) PA8650501A1 (es)
PE (1) PE20061033A1 (es)
TW (1) TW200619215A (es)
WO (1) WO2006047288A2 (es)

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US7435837B2 (en) * 2003-10-24 2008-10-14 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US20050261347A1 (en) * 2003-10-24 2005-11-24 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
GT200500297A (es) * 2004-10-21 2006-10-27 Sintesis asimetrica de dehidrobenzofuranos sustituidos
PE20071432A1 (es) * 2005-04-22 2007-01-24 Wyeth Corp Derivados de dihidrobenzofurano como agonistas o agonistas parciales de receptores metaloninergicos
US7365095B2 (en) * 2005-04-22 2008-04-29 Wyeth Chromane and chromene derivatives and uses thereof
MX2007013023A (es) * 2005-04-22 2007-12-13 Wyeth Corp Tratamiento del dolor.
PE20061335A1 (es) * 2005-04-22 2006-12-29 Wyeth Corp Compuestos derivados de benzodioxano y benzodioxolano como moduladores del receptor 5-ht2c
BRPI0610037A2 (pt) * 2005-04-22 2010-05-25 Wyeth Corp derivados de dihidrobenzofurano e uso dos mesmos
GT200600163A (es) * 2005-04-22 2007-03-14 Nuevas combinaciones terapeuticas para el tratamiento o la prevencion de la depresion
CA2604916A1 (en) * 2005-04-22 2006-11-02 Wyeth Dihydrobenzofuran derivatives and uses thereof
MX2007013026A (es) * 2005-04-22 2008-01-11 Wyeth Corp Combinaciones terapeuticas para el tratamiento o prevencion de trastornos psicoticos.
US7368477B2 (en) * 2005-04-22 2008-05-06 Wyeth Benzofuranyl alkanamine derivatives and uses thereof
EP1879875A1 (en) * 2005-04-22 2008-01-23 Wyeth Crystal forms opf {[(2r)-7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methyl}amine hydrochloride
GT200600162A (es) * 2005-04-24 2007-03-14 Metodos para modular la funcion de la vejiga
CL2007000775A1 (es) * 2006-03-24 2008-01-25 Wyeth Corp Uso de compuestos derivados de benzofurano para el tratamiento de un desorden cognitivo.
WO2012030953A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level
GB2486631A (en) * 2010-12-01 2012-06-27 Univ Sheffield Phenol/quinone boronic acids/esters and method of preparation thereof
WO2015066344A1 (en) 2013-11-01 2015-05-07 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use
CN109776465B (zh) * 2019-03-22 2023-06-06 国网湖南省电力有限公司 一种具有c2季碳中心的苯并二氢呋喃衍生物的合成方法
CN110283150A (zh) * 2019-07-12 2019-09-27 南开大学 一类手性二氢苯并呋喃的不对称合成方法
EP3878447A1 (en) 2020-03-11 2021-09-15 InterAx Biotech AG Beta adrenergic receptor antagonists
CN114560754A (zh) * 2022-02-25 2022-05-31 滁州学院 一种烷基醇的制备方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100327264B1 (ko) * 1993-10-29 2002-07-02 요시히로 미와 인돌유도체,그의염및이를함유하는심질환치료제
KR100186661B1 (ko) * 1994-07-07 1999-05-01 유미꾸라 레이이찌 신규 2,3-디히드로벤조푸란 유도체, 그의 제조 방법 및 용도
JPH09227562A (ja) * 1996-02-23 1997-09-02 Kowa Co インドール誘導体の製造法
JP2000007671A (ja) * 1998-06-25 2000-01-11 Asahi Chem Ind Co Ltd ２，３−ジヒドロベンゾフラン誘導体
JP2000080091A (ja) * 1998-06-26 2000-03-21 Asahi Chem Ind Co Ltd ２，３―ジヒドロベンゾフラン誘導体の製造方法
MXPA04003086A (es) * 2001-10-05 2004-09-06 Wyeth Corp Proceso para sintesis estereoselectiva de 2-hidroximetil-cromanos.
US7435837B2 (en) * 2003-10-24 2008-10-14 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US7728155B2 (en) * 2003-10-24 2010-06-01 Wyeth Llc Dihydrobenzofuranyl alkanamines and methods for using same as cns agents
US20050261347A1 (en) * 2003-10-24 2005-11-24 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US7516224B2 (en) * 2004-10-21 2009-04-07 Cisco Technology, Inc. Pseudowire termination directly on a router
GT200500297A (es) * 2004-10-21 2006-10-27 Sintesis asimetrica de dehidrobenzofuranos sustituidos
US7365095B2 (en) * 2005-04-22 2008-04-29 Wyeth Chromane and chromene derivatives and uses thereof
US7368477B2 (en) * 2005-04-22 2008-05-06 Wyeth Benzofuranyl alkanamine derivatives and uses thereof
PE20071432A1 (es) * 2005-04-22 2007-01-24 Wyeth Corp Derivados de dihidrobenzofurano como agonistas o agonistas parciales de receptores metaloninergicos
GT200600163A (es) * 2005-04-22 2007-03-14 Nuevas combinaciones terapeuticas para el tratamiento o la prevencion de la depresion
CA2604916A1 (en) * 2005-04-22 2006-11-02 Wyeth Dihydrobenzofuran derivatives and uses thereof
MX2007013026A (es) * 2005-04-22 2008-01-11 Wyeth Corp Combinaciones terapeuticas para el tratamiento o prevencion de trastornos psicoticos.
BRPI0610037A2 (pt) * 2005-04-22 2010-05-25 Wyeth Corp derivados de dihidrobenzofurano e uso dos mesmos
EP1879875A1 (en) * 2005-04-22 2008-01-23 Wyeth Crystal forms opf {[(2r)-7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methyl}amine hydrochloride
BRPI0610509A2 (pt) * 2005-04-22 2010-06-29 Wyeth Corp tratamento de dependência a drogas
PE20061335A1 (es) * 2005-04-22 2006-12-29 Wyeth Corp Compuestos derivados de benzodioxano y benzodioxolano como moduladores del receptor 5-ht2c
MX2007013023A (es) * 2005-04-22 2007-12-13 Wyeth Corp Tratamiento del dolor.
GT200600162A (es) * 2005-04-24 2007-03-14 Metodos para modular la funcion de la vejiga
US7593398B2 (en) * 2005-09-08 2009-09-22 Cisco Technology, Inc. Layer-two interworking applied to L2-L3 pseudowires

Also Published As

Publication number Publication date
AU2005299757A1 (en) 2006-05-04
BRPI0516236A (pt) 2008-08-26
CN101107238A (zh) 2008-01-16
PA8650501A1 (es) 2006-07-03
WO2006047288A2 (en) 2006-05-04
TW200619215A (en) 2006-06-16
CA2584775A1 (en) 2006-05-04
PE20061033A1 (es) 2006-11-08
EP1802598A2 (en) 2007-07-04
JP2008517929A (ja) 2008-05-29
US20060089405A1 (en) 2006-04-27
AR053980A1 (es) 2007-05-30
WO2006047288A3 (en) 2007-03-15
MX2007004637A (es) 2007-06-08

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