HRP20190876T1 - Novi adjuvantirani pripravci - Google Patents
Novi adjuvantirani pripravci Download PDFInfo
- Publication number
- HRP20190876T1 HRP20190876T1 HRP20190876TT HRP20190876T HRP20190876T1 HR P20190876 T1 HRP20190876 T1 HR P20190876T1 HR P20190876T T HRP20190876T T HR P20190876TT HR P20190876 T HRP20190876 T HR P20190876T HR P20190876 T1 HRP20190876 T1 HR P20190876T1
- Authority
- HR
- Croatia
- Prior art keywords
- virus
- accordance
- felv
- antigen
- avian influenza
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 4
- 239000002671 adjuvant Substances 0.000 title claims 3
- 239000000427 antigen Substances 0.000 claims 6
- 102000036639 antigens Human genes 0.000 claims 6
- 108091007433 antigens Proteins 0.000 claims 6
- 241000712461 unidentified influenza virus Species 0.000 claims 4
- 241000714165 Feline leukemia virus Species 0.000 claims 3
- 241000700605 Viruses Species 0.000 claims 3
- 241000282326 Felis catus Species 0.000 claims 2
- 208000002979 Influenza in Birds Diseases 0.000 claims 2
- 229920002125 Sokalan® Polymers 0.000 claims 2
- 229930182558 Sterol Natural products 0.000 claims 2
- UZQJVUCHXGYFLQ-AYDHOLPZSA-N [(2s,3r,4s,5r,6r)-4-[(2s,3r,4s,5r,6r)-4-[(2r,3r,4s,5r,6r)-4-[(2s,3r,4s,5r,6r)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-6-(hy Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O)O[C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O)O[C@H]1CC[C@]2(C)[C@H]3CC=C4[C@@]([C@@]3(CC[C@H]2[C@@]1(C=O)C)C)(C)CC(O)[C@]1(CCC(CC14)(C)C)C(=O)O[C@H]1[C@@H]([C@@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O[C@H]4[C@@H]([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O)[C@H](O)[C@@H](CO)O4)O)[C@H](O)[C@@H](CO)O3)O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UZQJVUCHXGYFLQ-AYDHOLPZSA-N 0.000 claims 2
- 230000000890 antigenic effect Effects 0.000 claims 2
- 206010064097 avian influenza Diseases 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 150000003432 sterols Chemical class 0.000 claims 2
- 235000003702 sterols Nutrition 0.000 claims 2
- 101800001467 Envelope glycoprotein E2 Proteins 0.000 claims 1
- 101900302604 Feline leukemia virus Surface protein Proteins 0.000 claims 1
- 101800001271 Surface protein Proteins 0.000 claims 1
- PSLWZOIUBRXAQW-UHFFFAOYSA-M dimethyl(dioctadecyl)azanium;bromide Chemical compound [Br-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC PSLWZOIUBRXAQW-UHFFFAOYSA-M 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Classifications
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- C12N2740/10011—Retroviridae
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- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
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- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16151—Methods of production or purification of viral material
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- C12N2770/00011—Details
- C12N2770/20011—Coronaviridae
- C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
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- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2770/00011—Details
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7623208P | 2008-06-27 | 2008-06-27 | |
| US21455709P | 2009-04-24 | 2009-04-24 | |
| EP15197967.1A EP3056214B1 (en) | 2008-06-27 | 2009-06-24 | Novel adjuvant compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20190876T1 true HRP20190876T1 (hr) | 2019-07-12 |
Family
ID=41445049
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20190876TT HRP20190876T1 (hr) | 2008-06-27 | 2019-05-13 | Novi adjuvantirani pripravci |
Country Status (29)
| Country | Link |
|---|---|
| US (6) | US8580280B2 (https=) |
| EP (4) | EP3552625A1 (https=) |
| JP (5) | JP5659332B2 (https=) |
| KR (1) | KR101333852B1 (https=) |
| CN (4) | CN104758929B (https=) |
| AR (1) | AR072378A1 (https=) |
| AU (1) | AU2009263759B2 (https=) |
| BR (2) | BRPI0913954B1 (https=) |
| CA (3) | CA2960846C (https=) |
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Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8444989B1 (en) * | 2008-04-18 | 2013-05-21 | Boehringer Ingelheim Vetmedica Gmbh | One dose vaccination against mycoplasma infections of pigs |
| MX2010014026A (es) * | 2008-06-27 | 2011-02-15 | Pfizer | Composiciones adyuvantes novedosas. |
| TWI351288B (en) * | 2008-07-04 | 2011-11-01 | Univ Nat Pingtung Sci & Tech | Cpg dna adjuvant in avian vaccines |
| US8552165B2 (en) * | 2008-12-09 | 2013-10-08 | Heather Davis | Immunostimulatory oligonucleotides |
| HUE027823T2 (hu) | 2008-12-09 | 2016-11-28 | Coley Pharm Group Inc | Immunstimuláló oligonukleotidok |
| CN107582526A (zh) * | 2009-08-12 | 2018-01-16 | 希格默伊德药业有限公司 | 包含聚合物基质和油相的免疫调节组合物 |
| FR2957803B1 (fr) * | 2010-03-24 | 2012-06-01 | Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic | Diluants adjuvants de vaccins vivants pour maladies porcines |
| NZ603527A (en) * | 2010-05-28 | 2014-10-31 | Zoetis Belgium S A | Vaccines comprising cholesterol and cpg as sole adjuvant - carrier molecules |
| MX345704B (es) | 2011-06-10 | 2017-02-10 | Novartis Tiergesundheit Ag | Vacuna bovinas y métodos. |
| US10047116B2 (en) * | 2011-10-03 | 2018-08-14 | Mx Adjuvac Ab | Nanoparticles, process for preparation and use thereof as carrier for amphipatic and hydrophobic molecules in fields of medicine including cancer treatment and food related compounds |
| CA2866170A1 (en) | 2012-03-12 | 2013-09-19 | Advanced Bioadjuvants, Llc | Adjuvant and vaccine compositions |
| AU2013370982C9 (en) * | 2012-12-28 | 2019-01-24 | Boehringer Ingelheim Vetmedica Gmbh | Immunogenic composition comprising mycoplasma antigens |
| MX361273B (es) | 2012-12-28 | 2018-12-03 | Boehringer Ingelheim Vetmedica Gmbh | Metodo para obtener una vacuna de mycoplasma. |
| CN103127495B (zh) * | 2013-01-28 | 2015-04-08 | 重庆市畜牧科学院 | 二联灭活苗的制剂及其制备方法 |
| MX2016002903A (es) * | 2013-09-05 | 2016-06-06 | Zoetis Services Llc | Composiciones inmunogenas de la glicoproteina g de los virus hendra y nipah. |
| KR101943171B1 (ko) | 2013-09-19 | 2019-01-29 | 조에티스 서비시즈 엘엘씨 | 유성 아쥬반트 |
| AU2014337452A1 (en) | 2013-10-17 | 2016-04-21 | Zoetis Services Llc | Methods and compositions for treatment of S. equi infection |
| EP4241853B1 (en) | 2013-11-26 | 2026-02-11 | Zoetis Services LLC | Compositions for induction of immune response |
| PL3223846T3 (pl) * | 2014-11-26 | 2024-03-11 | Huvepharma, Inc. | Kompozycje adiuwantowe i powiązane sposoby |
| US10195261B2 (en) | 2014-11-26 | 2019-02-05 | VaxLiant, LLC | Adjuvant compositions and related methods |
| DK3244920T5 (da) | 2015-01-16 | 2024-10-07 | Zoetis Services Llc | Mund- og klovsyge-vaccine |
| US9636397B2 (en) * | 2015-03-24 | 2017-05-02 | VaxLiant, LLC | Adjuvant compositions and related methods |
| CN104771754B (zh) * | 2015-04-02 | 2018-02-13 | 武汉科前生物股份有限公司 | 一种猪圆环病毒2型灭活疫苗水性佐剂及应用 |
| CN106267183B (zh) * | 2015-06-09 | 2023-02-28 | 普莱柯生物工程股份有限公司 | 含有佐剂的活疫苗组合物及其制备方法和应用 |
| CN106344920B (zh) * | 2015-07-16 | 2020-11-27 | 普莱柯生物工程股份有限公司 | 一种疫苗用佐剂及其应用 |
| US10456459B2 (en) | 2015-07-20 | 2019-10-29 | Zoetis Services Llc | Liposomal adjuvant compositions |
| AU2016297529B2 (en) * | 2015-07-20 | 2021-09-09 | Zoetis Services Llc | Liposomal adjuvant compositions |
| SG10201913547YA (en) * | 2015-10-19 | 2020-02-27 | Cadila Healthcare Ltd | New adjuvant and vaccine composition containing the same |
| EP3402878A1 (en) | 2016-01-11 | 2018-11-21 | Zoetis Services LLC | Novel cross protective vaccine compositions for porcine epidemic diarrhea virus |
| EP3432922B1 (en) | 2016-03-21 | 2020-02-19 | South Dakota Board of Regents | Orf virus-based platform for vaccine delivery |
| MX2018014857A (es) | 2016-06-02 | 2019-03-07 | Zoetis Services Llc | Vacuna contra la bronquitis infecciosa. |
| WO2018119142A1 (en) | 2016-12-21 | 2018-06-28 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| GB201703529D0 (en) | 2017-03-06 | 2017-04-19 | Cambridge Entpr Ltd | Vaccine composition |
| US10092604B1 (en) * | 2017-12-21 | 2018-10-09 | Bioceuticals Pte. Ltd. | Methods for treatment of skin infectious diseases using microorganisms |
| AU2019236328B2 (en) | 2018-03-16 | 2025-10-09 | Zoetis Services Llc | Peptide vaccines against Interleukin-31 |
| CN108853493A (zh) * | 2018-07-26 | 2018-11-23 | 中国人民解放军陆军军医大学 | 麦冬皂苷d及其纳米乳在制备疫苗佐剂中的应用 |
| WO2020023950A1 (en) | 2018-07-27 | 2020-01-30 | Research Development Foundation | Chimeric immunogenic polypeptides |
| WO2020055503A1 (en) * | 2018-09-14 | 2020-03-19 | Massachusetts Institute Of Technology | Nanoparticle vaccine adjuvant and methods of use thereof |
| CN109675028A (zh) * | 2019-03-01 | 2019-04-26 | 龙阔（苏州）生物工程有限公司 | 疫苗佐剂及其制备方法和应用及猪繁殖与呼吸综合征疫苗 |
| AU2020314625A1 (en) * | 2019-07-12 | 2022-02-03 | Research Development Foundation | Ehrlichia vaccines and immunogenic compositions |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| US20230263815A1 (en) | 2020-06-19 | 2023-08-24 | Kimberly-Clark Worldwide, Inc. | Saponin containing extracts prepared from hesperaloe useful in the treatment of non-human animals |
| CA3182453A1 (en) * | 2020-06-19 | 2021-12-23 | Ning Wei | Saponin containing extracts prepared from hesperaloe useful in the treatment of non-human animals |
| US12537071B1 (en) | 2020-07-22 | 2026-01-27 | David Gordon Bermudes | Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins |
| TWI884296B (zh) * | 2020-08-11 | 2025-05-21 | 美商碩騰服務公司 | 抗冠狀病毒疫苗 |
| CN114848807A (zh) * | 2021-02-04 | 2022-08-05 | 洛阳赛威生物科技有限公司 | 一种蜂胶佐剂组合物、及其制备方法以及应用 |
| US20230109193A1 (en) * | 2021-10-02 | 2023-04-06 | Massachusetts Institute Of Technology | Synergistic Combination of Alum and Non-Liposome, Non-Micelle Particle Vaccine Adjuvants |
| CN120712079A (zh) * | 2023-02-16 | 2025-09-26 | 瓦希纳诺公司 | 包含用于在没有任何佐剂的情况下经由阳离子多糖纳米颗粒递送灭活的完整细菌的系统的疫苗组合物 |
| WO2025006564A1 (en) | 2023-06-26 | 2025-01-02 | Research Development Foundation | Immunoreactive peptides |
| CN116747312B (zh) * | 2023-07-21 | 2025-08-08 | 辽宁成大生物股份有限公司 | 一种疫苗冻干保护剂、制剂及制备方法 |
| CN121360223A (zh) * | 2024-07-19 | 2026-01-20 | 硕腾服务有限责任公司 | 流感疫苗 |
Family Cites Families (98)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4264587A (en) * | 1979-08-01 | 1981-04-28 | Pedersen Niels C | Vaccine for preventing persistent feline leukemia viremia in cats |
| NZ221306A (en) * | 1986-08-15 | 1990-02-26 | Commw Scient Ind Res Org | 2-component immunoadjuvant comprising a mycobacterial free immunoadjuvant oil and a polycationic polyelectrolyte immunoadjuvant and vaccines thereof |
| US5084269A (en) | 1986-11-06 | 1992-01-28 | Kullenberg Fred W | Adjuvant for dose treatment with antigens |
| ES2037072T3 (es) | 1986-12-19 | 1993-06-16 | Duphar International Research B.V | Suspension coadyuvante estabilizada que comprende bromuro de dimetil-dioctadecil-amonio. |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| NZ230747A (en) * | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
| RU1615918C (ru) | 1989-05-22 | 1995-07-09 | Всероссийский научно-исследовательский институт защиты животных | Адъювант |
| JPH07502897A (ja) * | 1992-01-06 | 1995-03-30 | ファイザー・インコーポレイテッド | ネコ白血病ウイルスワクチン |
| ZA936095B (en) | 1992-08-21 | 1994-03-14 | Univ Melbourne | Cytokine applications. |
| US6764682B1 (en) | 1994-06-16 | 2004-07-20 | Aventis Pasteur Limited | Adjuvant compositions containing more than one adjuvant |
| US7935675B1 (en) | 1994-07-15 | 2011-05-03 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6846489B1 (en) * | 1995-04-25 | 2005-01-25 | Smithkline Beecham Biologicals S.A. | Vaccines containing a saponin and a sterol |
| ES2241042T3 (es) | 1996-10-11 | 2005-10-16 | The Regents Of The University Of California | Conjugados de polinucleotido inmunoestimulador/ molecula inmunomoduladora. |
| EP0855184A1 (en) | 1997-01-23 | 1998-07-29 | Grayson B. Dr. Lipford | Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination |
| WO1998037919A1 (en) | 1997-02-28 | 1998-09-03 | University Of Iowa Research Foundation | USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE IN THE TREATMENT OF LPS-ASSOCIATED DISORDERS |
| AU753688B2 (en) | 1997-03-10 | 2002-10-24 | Ottawa Civic Loeb Research Institute | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| US6406705B1 (en) * | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| BR9809426A (pt) | 1997-04-30 | 2000-06-13 | Merieux Oravax | Composição de vacina anti-helicobacter para uso pela via sistêmica subdiafragmática e método de imunização mucosal/parenteral combinado |
| CA2289702C (en) | 1997-05-14 | 2008-02-19 | Inex Pharmaceuticals Corp. | High efficiency encapsulation of charged therapeutic agents in lipid vesicles |
| WO1998055495A2 (en) | 1997-06-06 | 1998-12-10 | Dynavax Technologies Corporation | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof |
| EP1032416B1 (en) * | 1997-10-20 | 2007-01-24 | Bayer Corporation | Neospora vaccines |
| EP0953641A3 (en) * | 1998-03-26 | 2002-03-13 | Pfizer Products Inc. | Polynucleotide molecules encoding neospora proteins |
| ATE305507T1 (de) | 1998-05-14 | 2005-10-15 | Coley Pharm Gmbh | Verfahren zur regulierung der hematopoiese mit hilfe von cpg oligonukleotide |
| PT1077722E (pt) | 1998-05-22 | 2006-12-29 | Coley Pharm Group Inc | Produtos e composições para utilização na indução da imunidade mucosal |
| US20040247662A1 (en) | 1998-06-25 | 2004-12-09 | Dow Steven W. | Systemic immune activation method using nucleic acid-lipid complexes |
| US7049302B1 (en) | 1998-08-10 | 2006-05-23 | Antigenics Inc. | Compositions of CPG and saponin adjuvants and uses thereof |
| AU769539B2 (en) | 1999-01-29 | 2004-01-29 | Zoetis Services Llc | Adjuvants for use in vaccines |
| US8206749B1 (en) | 1999-02-26 | 2012-06-26 | Novartis Vaccines And Diagnostics, Inc. | Microemulsions with adsorbed macromolecules and microparticles |
| WO2000061184A2 (en) | 1999-04-08 | 2000-10-19 | Glenn Gregory M | Dry formulation for transcutaneous immunization |
| US6977245B2 (en) | 1999-04-12 | 2005-12-20 | The United States Of America As Represented By The Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| DE60014076T2 (de) | 1999-04-19 | 2005-10-13 | Glaxosmithkline Biologicals S.A. | Adjuvans-zusammensetzung, enthaltend saponin und ein immunstimulatorisches oligonukleotid |
| WO2000067023A1 (en) | 1999-04-29 | 2000-11-09 | Coley Pharmaceutical Gmbh | Screening for immunostimulatory dna functional modifyers |
| EP1322655B1 (en) | 2000-01-14 | 2007-11-14 | The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| EP1311288A1 (en) | 2000-01-20 | 2003-05-21 | Ottawa Health Research Institute | Immunostimulatory nucleic acids for inducing a th2 immune response |
| AT409085B (de) | 2000-01-28 | 2002-05-27 | Cistem Biotechnologies Gmbh | Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen |
| ES2248283T3 (es) | 2000-02-21 | 2006-03-16 | Pharmexa A/S | Nuevo procedimiento para reducir los niveles de amiloide. |
| AU5736601A (en) | 2000-05-01 | 2001-11-12 | Hybridon Inc | Modulation of oligonucleotide cpg-mediated immune stimulation by positional modification of nucleosides |
| AT410173B (de) | 2000-06-08 | 2003-02-25 | Cistem Biotechnologies Gmbh | Antigene zusammensetzung |
| GB0025577D0 (en) | 2000-10-18 | 2000-12-06 | Smithkline Beecham Biolog | Vaccine |
| ATE398175T1 (de) | 2000-12-08 | 2008-07-15 | Coley Pharmaceuticals Gmbh | Cpg-artige nukleinsäuren und verfahren zu ihrer verwendung |
| US7244438B2 (en) | 2001-01-05 | 2007-07-17 | Intercell Ag | Uses for polycationic compounds |
| US7713942B2 (en) | 2001-04-04 | 2010-05-11 | Nordic Vaccine Technology A/S | Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides |
| CA2439111A1 (en) | 2001-04-05 | 2002-10-17 | Chiron Corporation | Mucosal boosting following parenteral priming |
| US7105495B2 (en) | 2001-04-30 | 2006-09-12 | Idera Pharmaceuticals, Inc. | Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides |
| JP4188092B2 (ja) | 2001-05-21 | 2008-11-26 | インターツェル・アクチェンゲゼルシャフト | 免疫促進性オリゴデオキシ核酸分子 |
| EP1395262A4 (en) * | 2001-06-15 | 2006-04-12 | Ribapharm Corp | NUCLEOSIDE-VACCINE-ADJUVANTS |
| EP2027873B8 (en) * | 2001-07-02 | 2015-11-11 | Zoetis Services LLC | One dose vaccination with mycoplasma hyopneumoniae |
| CN1612749A (zh) * | 2001-07-02 | 2005-05-04 | 辉瑞产品公司 | 用于减弱牲畜体内牛支原体肺炎的猪肺炎支原体疫苗和方法 |
| US7666674B2 (en) | 2001-07-27 | 2010-02-23 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo |
| EP1501359A4 (en) | 2001-08-03 | 2007-04-18 | Celldex Therapeutics Inc | IMMUNOSTIMULATING OLIGONUCLEOTIDE-CONTAINING COMPOSITIONS AND USES THEREOF FOR IMPROVING FC-RECEPTOR-MEDIATED IMMUNOTHERAPIES |
| JP4607452B2 (ja) | 2001-08-07 | 2011-01-05 | ダイナバックス テクノロジーズ コーポレイション | 免疫調節性組成物、製剤およびその使用方法 |
| US20030138434A1 (en) | 2001-08-13 | 2003-07-24 | Campbell Robert L. | Agents for enhancing the immune response |
| IL160157A0 (en) | 2001-08-17 | 2004-07-25 | Coley Pharm Group Inc | Combination motif immune stimulation oligonucleotides with improved activity |
| CA2457514A1 (en) | 2001-08-28 | 2003-03-06 | Pfizer Products Inc. | Mycoplasma bovis challenge model, methods for administering m.bovis and methods for inducing pneumonic lung lesions |
| AU2002339224B2 (en) | 2001-09-14 | 2008-10-09 | Kuros Us Llc | Packaging of immunostimulatory substances into virus-like particles: method of preparation and use |
| WO2004012669A2 (en) | 2002-08-01 | 2004-02-12 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method of treating inflammatory arthropathies with suppressors of cpg oligonucleotides |
| US20030119774A1 (en) | 2001-09-25 | 2003-06-26 | Marianna Foldvari | Compositions and methods for stimulating an immune response |
| GB0123580D0 (en) | 2001-10-01 | 2001-11-21 | Glaxosmithkline Biolog Sa | Vaccine |
| JP2005508945A (ja) | 2001-10-06 | 2005-04-07 | メリアル リミテッド | Ｃｐｇ配合物及び関連方法 |
| US7276489B2 (en) | 2002-10-24 | 2007-10-02 | Idera Pharmaceuticals, Inc. | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends |
| JP2005516897A (ja) | 2001-11-07 | 2005-06-09 | イネックス ファーマシューティカルズ コーポレイション | 改善された粘膜のワクチン及びその使用方法 |
| JP2005519035A (ja) | 2001-12-07 | 2005-06-30 | インターツェル・アクチェンゲゼルシャフト | 免疫促進性オリゴデオキシヌクレオチド |
| EP1474432A1 (en) | 2002-02-04 | 2004-11-10 | Biomira Inc. | Immunostimulatory, covalently lipidated oligonucleotides |
| US8088388B2 (en) | 2002-02-14 | 2012-01-03 | United Biomedical, Inc. | Stabilized synthetic immunogen delivery system |
| CA2476854A1 (en) | 2002-02-19 | 2003-08-28 | Syntherica Corporation | Surrogate antibodies and methods of preparation and use thereof |
| US8153141B2 (en) | 2002-04-04 | 2012-04-10 | Coley Pharmaceutical Gmbh | Immunostimulatory G, U-containing oligoribonucleotides |
| AU2003262379A1 (en) | 2002-04-16 | 2003-11-03 | Auburn University | TRANSIENT AND/OR PERMANENT MODIFICATION OF SEXUAL BEHAVIOR AND/OR FERTILITY USING RECOMBINANT CHIMERIC GnRH |
| CN101160399A (zh) | 2002-04-22 | 2008-04-09 | 拜奥尼茨生命科学公司 | 寡核苷酸组合物及其在调节免疫应答中的应用 |
| KR100456681B1 (ko) | 2002-05-22 | 2004-11-10 | 주식회사 대웅 | 박테리아의 염색체 ｄｎａ 파쇄물과 비독성리포폴리사카라이드를 포함하는 면역강화 및 조절 조성물 |
| JP2005528899A (ja) | 2002-05-28 | 2005-09-29 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | 抗原提示細胞の生成方法 |
| CA2388049A1 (en) | 2002-05-30 | 2003-11-30 | Immunotech S.A. | Immunostimulatory oligonucleotides and uses thereof |
| SE0201701D0 (sv) | 2002-06-05 | 2002-06-05 | Gotovax Ab | Treatment of epithelial tumors and infections |
| WO2003103586A2 (en) | 2002-06-05 | 2003-12-18 | Coley Pharmaceutical Group, Inc. | Method for treating autoimmune or inflammatory diseases with combinations of inhibitory oligonucleotides and small molecule antagonists of immunostimulatory cpg nucleic acids |
| NZ539746A (en) | 2002-11-05 | 2008-03-28 | James Hardie Int Finance Bv | Method and apparatus for producing calcium silicate hydrate |
| PL378001A1 (pl) * | 2003-01-29 | 2006-02-20 | Pfizer Products Inc. | Szczepionki przeciw Bordetella bronchiseptica dla psów |
| AU2003900767A0 (en) * | 2003-02-21 | 2003-03-13 | St Vincent's Hospital Sydney Limited | Idiotypic vaccine |
| EP1605972A2 (en) | 2003-03-26 | 2005-12-21 | Cytos Biotechnology AG | Hiv-peptide-carrier-conjugates |
| KR100720213B1 (ko) | 2003-04-04 | 2007-05-21 | 화이자 프로덕츠 인코포레이티드 | 미세 유동화된 수중 유적형 유화액 및 백신 조성물 |
| SE0301998D0 (sv) * | 2003-07-07 | 2003-07-07 | Isconova Ab | Quil A fraction with low toxicity and use thereof |
| GB0323965D0 (en) * | 2003-10-13 | 2003-11-19 | Glaxosmithkline Biolog Sa | Immunogenic compositions |
| WO2005107797A1 (en) | 2004-03-09 | 2005-11-17 | Chiron Corporation | Influenza virus vaccines |
| AU2005230708B2 (en) * | 2004-04-05 | 2009-01-15 | Zoetis Services Llc | Microfluidized oil-in-water emulsions and vaccine compositions |
| CA2583061C (en) * | 2004-10-06 | 2015-02-17 | Kwang Guan Tay | Antibody production method |
| GB0426481D0 (en) * | 2004-12-02 | 2005-01-05 | Vaccine Technology Ltd | Composition |
| AU2006231916A1 (en) * | 2005-04-07 | 2006-10-12 | Pharmacia & Upjohn Company Llc | Formulations and process for production of Bordetella bronchiseptica p68 antigen and vaccines |
| WO2006116458A2 (en) * | 2005-04-26 | 2006-11-02 | Coley Pharmaceutical Gmbh | Modified oligoribonucleotide analogs with enhances immunostimulatory activity |
| PH12011502633A1 (en) * | 2005-10-07 | 2012-11-12 | Zoetis P Llc | Vaccines and methods to treat canine influenza |
| WO2008051245A2 (en) * | 2005-12-02 | 2008-05-02 | Novartis Ag | Nanoparticles for use in immunogenic compositions |
| ME00045B (me) * | 2006-01-26 | 2010-10-10 | Zoetis Services Llc | Nove kompozicije glikolipidnog adjuvansa |
| CA2637837A1 (en) * | 2006-01-26 | 2007-08-09 | Hx Diagnostics, Inc. | Monoclonal antibodies binding to avian influenza virus subtype h5 haemagglutinin and uses thereof |
| KR20090088944A (ko) * | 2006-12-15 | 2009-08-20 | 쉐링-프라우 리미티드 | 배양물 속에서 인플루엔자 바이러스를 복제하는 방법 |
| WO2008074487A2 (en) * | 2006-12-19 | 2008-06-26 | Novosom Ag | Lipids and lipid assemblies comprising transfection enhancer elements |
| US20080292663A1 (en) | 2007-05-22 | 2008-11-27 | Gerber Jay D | Adjuvant compositions and methods for delivering vaccines |
| CL2008001806A1 (es) | 2007-06-20 | 2008-09-05 | Wyeth Corp | Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion. |
| MX2010014026A (es) * | 2008-06-27 | 2011-02-15 | Pfizer | Composiciones adyuvantes novedosas. |
| JP6008345B2 (ja) | 2009-02-27 | 2016-10-19 | 東レ株式会社 | 免疫原性組成物 |
| US10456459B2 (en) * | 2015-07-20 | 2019-10-29 | Zoetis Services Llc | Liposomal adjuvant compositions |
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