EA201070014A1 - Внутрикожная вакцина против гриппа - Google Patents

Внутрикожная вакцина против гриппа

Info

Publication number
EA201070014A1
EA201070014A1 EA201070014A EA201070014A EA201070014A1 EA 201070014 A1 EA201070014 A1 EA 201070014A1 EA 201070014 A EA201070014 A EA 201070014A EA 201070014 A EA201070014 A EA 201070014A EA 201070014 A1 EA201070014 A1 EA 201070014A1
Authority
EA
Eurasian Patent Office
Prior art keywords
inlet
vaccine against
against influenza
relates
present
Prior art date
Application number
EA201070014A
Other languages
English (en)
Other versions
EA020953B1 (ru
Inventor
Кристиан Херцог
Хедвика Лазар
Original Assignee
Краселл Свитзерленд Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Краселл Свитзерленд Аг filed Critical Краселл Свитзерленд Аг
Publication of EA201070014A1 publication Critical patent/EA201070014A1/ru
Publication of EA020953B1 publication Critical patent/EA020953B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A61K39/135—Foot- and mouth-disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16123—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Настоящее изобретение относится к вакцинам против гриппа на виросомальной основе, используемым в производстве лекарств, которые вводят людям внутрикожно.. Настоящее изобретение относится к (тривалентной) композиции, содержащей низкие дозы антигена гемагглютинина (ГА) в виросомальной композиции, которая соответствует стандартам иммунного ответа в отношении уровней сероконверсии, кратности повышения GMT и уровней защиты, для ее применения в схемах вакцинации.
EA201070014A 2007-06-14 2008-06-11 Внутрикожная вакцина против гриппа EA020953B1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US94396707P 2007-06-14 2007-06-14
EP07110284 2007-06-14
US868807P 2007-12-21 2007-12-21
PCT/EP2008/057268 WO2008152052A1 (en) 2007-06-14 2008-06-11 Intradermal influenza vaccine

Publications (2)

Publication Number Publication Date
EA201070014A1 true EA201070014A1 (ru) 2010-04-30
EA020953B1 EA020953B1 (ru) 2015-03-31

Family

ID=38657168

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201070014A EA020953B1 (ru) 2007-06-14 2008-06-11 Внутрикожная вакцина против гриппа

Country Status (18)

Country Link
US (2) US20100136053A1 (ru)
EP (1) EP2175881B1 (ru)
JP (1) JP2010529166A (ru)
KR (1) KR20100045413A (ru)
CN (1) CN101754770B (ru)
AU (1) AU2008263970B2 (ru)
BR (1) BRPI0811459A8 (ru)
CA (1) CA2684699C (ru)
DK (1) DK2175881T3 (ru)
EA (1) EA020953B1 (ru)
ES (1) ES2391599T3 (ru)
HR (1) HRP20120825T1 (ru)
IL (1) IL202670A (ru)
MX (1) MX2009013118A (ru)
NZ (1) NZ580603A (ru)
PL (1) PL2175881T3 (ru)
PT (1) PT2175881E (ru)
WO (1) WO2008152052A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220163497A (ko) * 2010-06-01 2022-12-09 노파르티스 아게 동결건조하지 않는 인플루엔자 백신 항원의 농축
US20130039973A1 (en) * 2011-08-03 2013-02-14 Henry J. Smith Viral Immunogenic Compositions
US11523988B2 (en) 2018-11-29 2022-12-13 Catalent U.K. Swindon Zydis Limited Oral dispersible vaccine comprising virosomes

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Also Published As

Publication number Publication date
CN101754770A (zh) 2010-06-23
CN101754770B (zh) 2015-05-20
DK2175881T3 (da) 2012-10-22
NZ580603A (en) 2013-02-22
IL202670A (en) 2014-03-31
US20100136053A1 (en) 2010-06-03
AU2008263970B2 (en) 2014-01-30
ES2391599T3 (es) 2012-11-28
PT2175881E (pt) 2012-10-22
BRPI0811459A2 (pt) 2014-10-21
JP2010529166A (ja) 2010-08-26
EP2175881A1 (en) 2010-04-21
EA020953B1 (ru) 2015-03-31
US20130183340A1 (en) 2013-07-18
BRPI0811459A8 (pt) 2015-09-22
CA2684699A1 (en) 2008-12-18
EP2175881B1 (en) 2012-07-18
PL2175881T3 (pl) 2012-12-31
AU2008263970A1 (en) 2008-12-18
IL202670A0 (en) 2011-08-01
KR20100045413A (ko) 2010-05-03
CA2684699C (en) 2017-03-21
HRP20120825T1 (hr) 2012-11-30
WO2008152052A1 (en) 2008-12-18
MX2009013118A (es) 2010-03-04

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM