DE122011100053I1 - Influenza vakzinzusammensetzungen zur intradermaler verabreichung. - Google Patents
Influenza vakzinzusammensetzungen zur intradermaler verabreichung.Info
- Publication number
- DE122011100053I1 DE122011100053I1 DE201112100053 DE122011100053C DE122011100053I1 DE 122011100053 I1 DE122011100053 I1 DE 122011100053I1 DE 201112100053 DE201112100053 DE 201112100053 DE 122011100053 C DE122011100053 C DE 122011100053C DE 122011100053 I1 DE122011100053 I1 DE 122011100053I1
- Authority
- DE
- Germany
- Prior art keywords
- vaccine compositions
- influenza vaccine
- intradermal administration
- influenza
- intradermal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Surgical Instruments (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0104538A GB0104538D0 (en) | 2001-02-23 | 2001-02-23 | Novel Vaccine |
GB0107511A GB0107511D0 (en) | 2001-03-26 | 2001-03-26 | Novel vaccine |
GB0108365A GB0108365D0 (en) | 2001-04-03 | 2001-04-03 | Novel compounds |
PCT/EP2002/001844 WO2002074336A2 (en) | 2001-02-23 | 2002-02-21 | Influenza vaccine formulations for intradermal delivery |
Publications (1)
Publication Number | Publication Date |
---|---|
DE122011100053I1 true DE122011100053I1 (de) | 2012-03-15 |
Family
ID=27256080
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60239594T Expired - Lifetime DE60239594D1 (de) | 2001-02-23 | 2002-02-21 | Influenza vakzinzusammensetzungen zur intradermaler verabreichung |
DE201112100054 Pending DE122011100054I1 (de) | 2001-02-23 | 2011-09-29 | Influenza vakzinzusammensetzungen zur intradermaler verabreichung. |
DE201112100053 Pending DE122011100053I1 (de) | 2001-02-23 | 2011-09-29 | Influenza vakzinzusammensetzungen zur intradermaler verabreichung. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60239594T Expired - Lifetime DE60239594D1 (de) | 2001-02-23 | 2002-02-21 | Influenza vakzinzusammensetzungen zur intradermaler verabreichung |
DE201112100054 Pending DE122011100054I1 (de) | 2001-02-23 | 2011-09-29 | Influenza vakzinzusammensetzungen zur intradermaler verabreichung. |
Country Status (11)
Country | Link |
---|---|
US (4) | US20040071734A1 (de) |
EP (3) | EP2281573A3 (de) |
JP (5) | JP5208347B2 (de) |
AT (1) | ATE503493T1 (de) |
AU (1) | AU2002254901A1 (de) |
CA (1) | CA2438942A1 (de) |
CY (1) | CY1111553T1 (de) |
DE (3) | DE60239594D1 (de) |
DK (1) | DK1361890T3 (de) |
PT (1) | PT1361890E (de) |
WO (1) | WO2002074336A2 (de) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2383105C (en) * | 1999-09-24 | 2010-01-26 | Smithkline Beecham Biologicals S.A. | Intranasal influenza virus vaccine |
JP2004536785A (ja) * | 2001-02-23 | 2004-12-09 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 新規なワクチン |
PT1361890E (pt) * | 2001-02-23 | 2011-06-07 | Glaxosmithkline Biolog Sa | Formulações vacinais de influenza para distribuição intradérmica |
CA2445120A1 (en) * | 2001-04-27 | 2002-11-07 | Glaxosmithkline Biologicals Sa | Devices for the intradermal administration of influenza vaccines |
CN1253220C (zh) * | 2001-06-29 | 2006-04-26 | 贝克顿迪肯森公司 | 通过微管在真皮内输入疫苗和基因治疗剂 |
US20060110406A1 (en) | 2003-02-25 | 2006-05-25 | Medimmune Vaccines, Inc. | Refrigerator-temperature stable influenza vaccine compositions |
JP4617300B2 (ja) | 2003-02-25 | 2011-01-19 | メディミューン,エルエルシー | インフルエンザワクチン組成物を生成する方法 |
US7588774B2 (en) | 2003-05-12 | 2009-09-15 | Becton, Dickinson And Company | Molecules enhancing dermal delivery of influenza vaccines |
US20050123550A1 (en) * | 2003-05-12 | 2005-06-09 | Laurent Philippe E. | Molecules enhancing dermal delivery of influenza vaccines |
WO2005018539A2 (en) * | 2003-06-16 | 2005-03-03 | Medimmune Vaccines, Inc. | Influenza hemagglutinin and neuraminidase variants |
WO2005107797A1 (en) | 2004-03-09 | 2005-11-17 | Chiron Corporation | Influenza virus vaccines |
EP2769735B1 (de) * | 2004-10-06 | 2017-04-19 | MedImmune, LLC | Kühlschranktemperaturstabile Grippeimpfstoff-zusammensetzungen |
AU2005314563B2 (en) * | 2004-11-03 | 2011-06-30 | Seqirus UK Limited | Influenza vaccination |
WO2006098901A2 (en) | 2005-03-08 | 2006-09-21 | Medimmune Vaccines, Inc. | Influenza hemagglutinin and neuraminidase variants |
KR20070116650A (ko) * | 2005-03-23 | 2007-12-10 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 조성물 |
JP4828189B2 (ja) * | 2005-09-14 | 2011-11-30 | 雅美 森山 | 分泌型IgA及びIgG抗体誘導剤 |
ATE494906T1 (de) | 2005-11-01 | 2011-01-15 | Novartis Vaccines & Diagnostic | Von zellen stammende virale impfstoffe mit geringen mengen an rest-zell-dna |
CN102755645A (zh) | 2005-11-04 | 2012-10-31 | 诺华疫苗和诊断有限公司 | 佐剂配制的包含细胞因子诱导剂的流感疫苗 |
AU2006310163B2 (en) | 2005-11-04 | 2011-09-15 | Seqirus UK Limited | Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant |
JP2009514838A (ja) | 2005-11-04 | 2009-04-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | 細胞培養物において増殖されたインフルエンザウイルスから調製された非ビリオン抗原を含むアジュバントワクチン |
DE202006021242U1 (de) | 2005-11-04 | 2014-01-29 | Novartis Vaccines And Diagnostics S.R.L. | Emulsionen mit freiem wässrigen Phasen Tensid als Adjuvans für Spalt-Grippeimpfstoffe |
ES2377884T3 (es) | 2005-11-04 | 2012-04-02 | Novartis Vaccines And Diagnostics S.R.L. | Vacunas contra la gripe que incluyen combinaciones de adyuvantes particulados e inmunopotenciadores |
DK2478916T3 (da) | 2006-01-27 | 2020-06-15 | Seqirus Uk Ltd | Influenzavacciner indeholdende hæmagglutinin og matrixproteiner |
CA2646349A1 (en) * | 2006-03-24 | 2007-10-04 | Novartis Vaccines And Diagnostics Gmbh & Co Kg | Storage of influenza vaccines without refrigeration |
WO2008009309A1 (en) | 2006-07-17 | 2008-01-24 | Glaxosmithkline Biologicals S.A. | Influenza vaccine |
GB0614460D0 (en) | 2006-07-20 | 2006-08-30 | Novartis Ag | Vaccines |
ES2694805T7 (es) | 2006-09-11 | 2021-10-21 | Seqirus Uk Ltd | Fabricación de vacunas contra virus de la gripe sin usar huevos |
US20080124355A1 (en) | 2006-09-22 | 2008-05-29 | David Gordon Bermudes | Live bacterial vaccines for viral infection prophylaxis or treatment |
SG177141A1 (en) | 2006-12-06 | 2012-01-30 | Novartis Ag | Vaccines including antigen from four strains of influenza virus |
PE20090146A1 (es) | 2007-04-20 | 2009-03-23 | Glaxosmithkline Biolog Sa | Composicion inmunogenica contra el virus influenza |
EP2175881B1 (de) * | 2007-06-14 | 2012-07-18 | Crucell Switzerland AG | Intradermaler grippeimpfstoff |
EP2185191B1 (de) | 2007-06-27 | 2012-09-12 | Novartis AG | Influenzaimpfstoffe mit geringem zusatz |
GB0810305D0 (en) | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
WO2009081172A1 (en) | 2007-12-24 | 2009-07-02 | Novartis Ag | Assays for adsorbed influenza vaccines |
US8506966B2 (en) | 2008-02-22 | 2013-08-13 | Novartis Ag | Adjuvanted influenza vaccines for pediatric use |
CN101998990B (zh) | 2008-03-18 | 2013-11-27 | 诺华股份有限公司 | 流感病毒疫苗抗原制备方法的改进 |
CN102149405A (zh) * | 2008-07-11 | 2011-08-10 | 米迪缪尼股份有限公司 | 流感血凝素和神经氨酸酶变体 |
JP5182753B2 (ja) * | 2008-09-01 | 2013-04-17 | 富士フイルム株式会社 | インフルエンザ罹患リスクの予測方法 |
EP2361304A2 (de) | 2008-11-05 | 2011-08-31 | GlaxoSmithKline Biologicals S.A. | Neues verfahren |
US20120093860A1 (en) | 2009-02-10 | 2012-04-19 | Novartis Ag | Influenza vaccines with increased amounts of h3 antigen |
JP5642712B2 (ja) | 2009-02-10 | 2014-12-17 | ノバルティス アーゲー | 少ない量のスクアレンを含むインフルエンザワクチン |
EA201171032A1 (ru) | 2009-02-10 | 2012-02-28 | Новартис Аг | Схемы лечения с помощью вакцины против гриппа, связанного с пандемическими штаммами |
USH2284H1 (en) | 2009-04-27 | 2013-09-03 | Novartis Ag | Vaccines for protecting against influenza |
KR101800245B1 (ko) | 2009-05-21 | 2017-11-22 | 노파르티스 아게 | 비-내인성 pol i 프로모터를 사용하는 역 유전학 |
WO2011012999A1 (en) | 2009-07-31 | 2011-02-03 | Novartis Ag | Reverse genetics systems |
KR20120081587A (ko) | 2009-09-10 | 2012-07-19 | 노파르티스 아게 | 기도 질병에 대한 조합 백신 |
EP2491117B2 (de) | 2009-10-20 | 2017-06-28 | Novartis AG | Verbesserte methoden reverser genetik zur gewinnung von viren |
GB0918830D0 (en) * | 2009-10-27 | 2009-12-09 | Glaxosmithkline Biolog Niederl | Process |
EP2566323A2 (de) | 2010-05-06 | 2013-03-13 | Novartis AG | Organische peroxidverbindungen zur inaktivierung von mikroorganismen |
CA2800150C (en) | 2010-05-21 | 2018-09-04 | Novartis Ag | Influenza virus reassortment method |
CA2801151A1 (en) | 2010-06-01 | 2011-12-08 | Novartis Ag | Concentration of vaccine antigens with lyophilization |
KR20220163497A (ko) | 2010-06-01 | 2022-12-09 | 노파르티스 아게 | 동결건조하지 않는 인플루엔자 백신 항원의 농축 |
WO2011154976A2 (en) | 2010-06-08 | 2011-12-15 | Panacea Biotec Limited | Improved influenza vaccine |
US9517205B2 (en) | 2010-08-20 | 2016-12-13 | Seqirus UK Limited | Soluble needle arrays for delivery of influenza vaccines |
GB201216121D0 (en) | 2012-09-10 | 2012-10-24 | Novartis Ag | Sample quantification by disc centrifugation |
WO2013057715A1 (en) | 2011-10-20 | 2013-04-25 | Novartis Ag | Adjuvanted influenza b virus vaccines for pediatric priming |
GB201120000D0 (en) * | 2011-11-20 | 2012-01-04 | Glaxosmithkline Biolog Sa | Vaccine |
JP6054883B2 (ja) | 2012-03-02 | 2016-12-27 | ノバルティス アーゲー | インフルエンザウイルスの再集合 |
WO2013131898A1 (en) | 2012-03-06 | 2013-09-12 | Crucell Holland B.V. | Improved vaccination against influenza |
EP2855701A1 (de) | 2012-06-04 | 2015-04-08 | Novartis AG | Verbesserte sicherheitsprüfung |
GB201218195D0 (en) | 2012-10-10 | 2012-11-21 | Istituto Zooprofilattico Sperimentale Delle Venezie | Composition |
AU2013354219A1 (en) | 2012-12-03 | 2015-07-02 | Novartis Ag | Reassortant influenza a viren |
UY34506A (es) * | 2012-12-10 | 2014-06-30 | Fernando Amaury Ferreira Chiesa | Adyuvante de vacunación, preparación y vacunas que lo contienen |
AU2014204826A1 (en) | 2013-01-10 | 2015-07-09 | Seqirus UK Limited | Influenza virus immunogenic compositions and uses thereof |
AU2014229255B2 (en) | 2013-03-13 | 2018-12-13 | Novartis Ag | Influenza B virus reassortment |
JP2016521282A (ja) | 2013-05-10 | 2016-07-21 | ノバルティス アーゲー | インフルエンザワクチンにおけるナルコレプシーのリスクの回避 |
DE202013005130U1 (de) | 2013-06-05 | 2013-09-10 | Novartis Ag | Influenza Virus Reassortierung |
DE202013005100U1 (de) | 2013-06-05 | 2013-08-26 | Novartis Ag | Influenza Virus Reassortierung |
CA2914604A1 (en) | 2013-06-06 | 2014-12-11 | Novartis Ag | Influenza virus reassortment |
JP6373376B2 (ja) | 2013-11-15 | 2018-08-15 | ノバルティス アーゲー | 残留細胞培養不純物の除去 |
CA2897038C (en) | 2014-07-14 | 2016-10-04 | Novicol International Holding Inc. | Microbicidal composition comprising an octoxynol and a quinolizidine alkaloid compound or a source thereof |
US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
JP6719388B2 (ja) * | 2014-12-25 | 2020-07-08 | テルモ株式会社 | 皮内投与インフルエンザワクチン組成物 |
KR20180035807A (ko) | 2015-06-26 | 2018-04-06 | 세퀴러스 유케이 리미티드 | 항원적으로 매치된 인플루엔자 백신 |
BR112018000296A2 (pt) | 2015-07-07 | 2018-09-04 | Seqirus UK Limited | ensaios de potência de influenza |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
US20220168413A1 (en) | 2019-02-25 | 2022-06-02 | Seqirus UK Limited | Adjuvanted multivalent influenza vaccines |
US11471497B1 (en) | 2019-03-13 | 2022-10-18 | David Gordon Bermudes | Copper chelation therapeutics |
CN114929270A (zh) | 2019-11-07 | 2022-08-19 | 塞其里斯英国有限公司 | 用于生产具有减小的颗粒大小的病毒疫苗的组合物和方法 |
JP2023502650A (ja) | 2019-11-18 | 2023-01-25 | セキラス ピーティーワイ リミテッド | 遺伝子再集合インフルエンザウイルスを産生するための方法 |
US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
Family Cites Families (101)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5520A (en) | 1848-04-18 | Oegan-pipb | ||
US639A (en) | 1838-03-17 | of boston | ||
US1274081A (en) * | 1917-05-10 | 1918-07-30 | Herman A Metz | Hypodermic needle. |
US1436707A (en) * | 1921-08-10 | 1922-11-28 | American Platinum Works | Adjustable and safety regulating device for hypodermic needles |
FR1001668A (fr) * | 1946-06-17 | 1952-02-26 | Seringue pour anesthésie tronculaire du maxillaire inférieur | |
US2559474A (en) * | 1950-03-09 | 1951-07-03 | Sonco Inc | Hypodermic and spinal syringe |
FR1072399A (fr) * | 1961-01-07 | 1954-09-13 | Injecteur intra-dermique | |
US3400715A (en) * | 1966-01-04 | 1968-09-10 | Halvard J. Pederson | Attachment for injection apparatus |
US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
BE795384A (fr) * | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
JPS52132590A (en) | 1976-04-27 | 1977-11-07 | Haabaato Bogeruman Jiyosefu | Injector |
US4270537A (en) | 1979-11-19 | 1981-06-02 | Romaine Richard A | Automatic hypodermic syringe |
JPS5695058A (en) | 1979-12-10 | 1981-08-01 | Toyo Jozo Kk | Microosyringe |
DD155875A1 (de) | 1980-12-31 | 1982-07-14 | Willy Nordheim | Verfahren zur herstellung eines ballaststoffarmen inaktivierten influenzaimpfstoffes |
US4436727A (en) | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
JPS6153226A (ja) * | 1984-08-24 | 1986-03-17 | Chemo Sero Therapeut Res Inst | 単純ヘルペスサブユニツトワクチンの精製方法 |
US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
JPH0688911B2 (ja) * | 1985-06-06 | 1994-11-09 | 国立予防衛生研究所長 | インフルエンザワクチン及びその製造方法 |
CA1283827C (en) | 1986-12-18 | 1991-05-07 | Giorgio Cirelli | Appliance for injection of liquid formulations |
GB8704027D0 (en) | 1987-02-20 | 1987-03-25 | Owen Mumford Ltd | Syringe needle combination |
CA1331443C (en) | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
US6056716A (en) * | 1987-06-08 | 2000-05-02 | D'antonio Consultants International Inc. | Hypodermic fluid dispenser |
US5569190A (en) * | 1987-06-08 | 1996-10-29 | D'antonio; Nicholas F. | Hypodermic fluid dispenser |
US5080648A (en) * | 1987-06-08 | 1992-01-14 | Antonio Nicholas F D | Hypodermic fluid dispenser |
US4941880A (en) | 1987-06-19 | 1990-07-17 | Bioject, Inc. | Pre-filled ampule and non-invasive hypodermic injection device assembly |
US4790824A (en) | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
US4940460A (en) | 1987-06-19 | 1990-07-10 | Bioject, Inc. | Patient-fillable and non-invasive hypodermic injection device assembly |
GB2206794A (en) | 1987-07-14 | 1989-01-18 | Richard Kiteley Power | Syringe |
DE3734306A1 (de) | 1987-10-10 | 1989-04-27 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung fuer fliessfaehige medien |
US5195526A (en) * | 1988-03-11 | 1993-03-23 | Michelson Gary K | Spinal marker needle |
US5339163A (en) | 1988-03-16 | 1994-08-16 | Canon Kabushiki Kaisha | Automatic exposure control device using plural image plane detection areas |
US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
FR2638359A1 (fr) | 1988-11-03 | 1990-05-04 | Tino Dalto | Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau |
US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
US5064413A (en) | 1989-11-09 | 1991-11-12 | Bioject, Inc. | Needleless hypodermic injection device |
DE4005528C2 (de) | 1990-02-22 | 1998-01-15 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für Medien |
US5279581A (en) | 1990-05-09 | 1994-01-18 | Firth John R | Disposable self-shielding hypodermic syringe |
US5190521A (en) | 1990-08-22 | 1993-03-02 | Tecnol Medical Products, Inc. | Apparatus and method for raising a skin wheal and anesthetizing skin |
US5527288A (en) | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
TW279133B (de) * | 1990-12-13 | 1996-06-21 | Elan Med Tech | |
DE4127887C1 (en) | 1991-08-22 | 1993-01-28 | Manfred Prof. Dr. 8520 Erlangen De Herbst | Subcutaneous medicine delivery device preventing needle from exceeding required depth - comprises tube attached with needle free to move on wedge shaped needle holder with needle penetration holes of different depth |
GB9118204D0 (en) | 1991-08-23 | 1991-10-09 | Weston Terence E | Needle-less injector |
SE9102652D0 (sv) | 1991-09-13 | 1991-09-13 | Kabi Pharmacia Ab | Injection needle arrangement |
JP3723231B2 (ja) | 1991-12-23 | 2005-12-07 | ディミナコ アクチェンゲゼルシャフト | アジュバント |
US5328483A (en) | 1992-02-27 | 1994-07-12 | Jacoby Richard M | Intradermal injection device with medication and needle guard |
IL101720A (en) * | 1992-04-29 | 1998-09-24 | Mali Tech Ltd | Needle for syringe or the like |
JP3755890B2 (ja) | 1992-06-25 | 2006-03-15 | スミスクライン・ビーチャム・バイオロジカルス(ソシエテ・アノニム) | アジュバント含有ワクチン組成物 |
US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
US5569189A (en) | 1992-09-28 | 1996-10-29 | Equidyne Systems, Inc. | hypodermic jet injector |
US5334144A (en) | 1992-10-30 | 1994-08-02 | Becton, Dickinson And Company | Single use disposable needleless injector |
WO1994019013A1 (en) * | 1993-02-19 | 1994-09-01 | Smithkline Beecham Corporation | Influenza vaccine compositions containing 3-o-deacylated monophosphoryl lipid a |
JPH08506592A (ja) * | 1993-02-19 | 1996-07-16 | スミスクライン・ビーチャム・コーポレイション | 3−o−脱アシル化モノホスホリル脂質A含有のインフルエンザワクチン組成物 |
CN1087176C (zh) | 1993-03-23 | 2002-07-10 | 史密斯克莱·比奇曼生物公司 | 含有3-o脱酰基单磷酰脂a的疫苗制剂 |
IE68890B1 (en) * | 1993-04-08 | 1996-07-24 | Elan Med Tech | Intradermal delivery device |
ES2370937T3 (es) * | 1993-09-13 | 2011-12-23 | Protein Sciences Corporation | Un método para producir vacunas antigripales polivalentes a base de hemaglutinina. |
US6485729B1 (en) * | 1993-09-13 | 2002-11-26 | Protein Sciences Corporation | Neuraminidase-supplemented compositions |
CA2171563A1 (en) | 1993-09-14 | 1995-03-23 | Eric Le Cheminant | Injection device |
US5997501A (en) * | 1993-11-18 | 1999-12-07 | Elan Corporation, Plc | Intradermal drug delivery device |
GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
WO1995024176A1 (en) | 1994-03-07 | 1995-09-14 | Bioject, Inc. | Ampule filling device |
US5466220A (en) | 1994-03-08 | 1995-11-14 | Bioject, Inc. | Drug vial mixing and transfer device |
JPH07299143A (ja) | 1994-05-09 | 1995-11-14 | Kenji Tsubota | 医科用注射針 |
AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
US5599302A (en) | 1995-01-09 | 1997-02-04 | Medi-Ject Corporation | Medical injection system and method, gas spring thereof and launching device using gas spring |
UA56132C2 (uk) * | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
GB9620795D0 (en) * | 1996-10-05 | 1996-11-20 | Smithkline Beecham Plc | Vaccines |
US5730723A (en) | 1995-10-10 | 1998-03-24 | Visionary Medical Products Corporation, Inc. | Gas pressured needle-less injection device and method |
US7223739B1 (en) * | 1995-06-07 | 2007-05-29 | Powderject Vaccines, Inc. | Adjuvanted genetic vaccines |
SE9502285D0 (sv) | 1995-06-22 | 1995-06-22 | Pharmacia Ab | Improvements related to injections |
US5893397A (en) | 1996-01-12 | 1999-04-13 | Bioject Inc. | Medication vial/syringe liquid-transfer apparatus |
GB9607549D0 (en) | 1996-04-11 | 1996-06-12 | Weston Medical Ltd | Spring-powered dispensing device |
BR9705023A (pt) * | 1996-10-12 | 1998-12-01 | Luk Getriebe Systeme Gmbh | Veículo automotor |
US5776107A (en) * | 1996-12-31 | 1998-07-07 | Delab | Injection device |
CN1326564C (zh) | 1997-04-01 | 2007-07-18 | 科里克萨有限公司 | 单磷酰基脂质a的水性免疫佐剂组合物 |
US5993412A (en) | 1997-05-19 | 1999-11-30 | Bioject, Inc. | Injection apparatus |
US5944700A (en) | 1997-09-26 | 1999-08-31 | Becton, Dickinson And Company | Adjustable injection length pen needle |
US6482176B1 (en) | 1997-11-27 | 2002-11-19 | Disetronic Licensing Ag | Method and device for controlling the introduction depth of an injection needle |
IT1298087B1 (it) * | 1998-01-08 | 1999-12-20 | Fiderm S R L | Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni |
JP4118399B2 (ja) | 1998-07-21 | 2008-07-16 | テルモ株式会社 | 注射針用穿刺調整具およびそれを備えた注射針組立体 |
US6309374B1 (en) | 1998-08-03 | 2001-10-30 | Insite Vision Incorporated | Injection apparatus and method of using same |
US6159472A (en) | 1998-11-16 | 2000-12-12 | Akzo Nobel N.V. | Intradermal Avian immunization with inactivated vaccines |
CA2365296A1 (en) | 1999-03-19 | 2000-09-28 | Pierre Michel Desmons | Vaccine |
WO2000074763A2 (en) | 1999-06-04 | 2000-12-14 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
US6623457B1 (en) * | 1999-09-22 | 2003-09-23 | Becton, Dickinson And Company | Method and apparatus for the transdermal administration of a substance |
CA2383105C (en) | 1999-09-24 | 2010-01-26 | Smithkline Beecham Biologicals S.A. | Intranasal influenza virus vaccine |
BR0014285A (pt) * | 1999-09-24 | 2002-05-21 | Smithkline Beecham Biolog | Adjuvantes compreendendo um éster ou éter de alquila de polioxietileno e pelo menos um tensoativo não-iÈnico |
US6569123B2 (en) * | 1999-10-14 | 2003-05-27 | Becton, Dickinson And Company | Prefillable intradermal injector |
US6776776B2 (en) * | 1999-10-14 | 2004-08-17 | Becton, Dickinson And Company | Prefillable intradermal delivery device |
US8465468B1 (en) | 2000-06-29 | 2013-06-18 | Becton, Dickinson And Company | Intradermal delivery of substances |
US6843781B2 (en) * | 1999-10-14 | 2005-01-18 | Becton, Dickinson And Company | Intradermal needle |
US20020193740A1 (en) * | 1999-10-14 | 2002-12-19 | Alchas Paul G. | Method of intradermally injecting substances |
US6494865B1 (en) * | 1999-10-14 | 2002-12-17 | Becton Dickinson And Company | Intradermal delivery device including a needle assembly |
US6569143B2 (en) * | 1999-10-14 | 2003-05-27 | Becton, Dickinson And Company | Method of intradermally injecting substances |
DE19950530A1 (de) | 1999-10-20 | 2001-06-13 | Frank Neveling | Spritze zur intrakutanen Injektion |
JP2004536785A (ja) * | 2001-02-23 | 2004-12-09 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 新規なワクチン |
PT1361890E (pt) | 2001-02-23 | 2011-06-07 | Glaxosmithkline Biolog Sa | Formulações vacinais de influenza para distribuição intradérmica |
GB0109297D0 (en) | 2001-04-12 | 2001-05-30 | Glaxosmithkline Biolog Sa | Vaccine |
CA2445120A1 (en) * | 2001-04-27 | 2002-11-07 | Glaxosmithkline Biologicals Sa | Devices for the intradermal administration of influenza vaccines |
CN1253220C (zh) * | 2001-06-29 | 2006-04-26 | 贝克顿迪肯森公司 | 通过微管在真皮内输入疫苗和基因治疗剂 |
-
2002
- 2002-02-21 PT PT02724176T patent/PT1361890E/pt unknown
- 2002-02-21 WO PCT/EP2002/001844 patent/WO2002074336A2/en active Application Filing
- 2002-02-21 EP EP20100178427 patent/EP2281573A3/de not_active Withdrawn
- 2002-02-21 AT AT02724176T patent/ATE503493T1/de active
- 2002-02-21 EP EP02724176A patent/EP1361890B1/de not_active Revoked
- 2002-02-21 US US10/469,191 patent/US20040071734A1/en not_active Abandoned
- 2002-02-21 JP JP2002573043A patent/JP5208347B2/ja not_active Expired - Fee Related
- 2002-02-21 AU AU2002254901A patent/AU2002254901A1/en not_active Abandoned
- 2002-02-21 DE DE60239594T patent/DE60239594D1/de not_active Expired - Lifetime
- 2002-02-21 CA CA002438942A patent/CA2438942A1/en not_active Abandoned
- 2002-02-21 DK DK02724176.9T patent/DK1361890T3/da active
- 2002-02-21 EP EP10178402.3A patent/EP2269639B1/de not_active Expired - Lifetime
-
2007
- 2007-06-13 US US11/762,488 patent/US8557251B2/en not_active Expired - Fee Related
-
2009
- 2009-03-17 JP JP2009063830A patent/JP5960380B2/ja not_active Expired - Fee Related
-
2011
- 2011-06-08 CY CY20111100550T patent/CY1111553T1/el unknown
- 2011-09-15 JP JP2011201447A patent/JP6076592B2/ja not_active Expired - Fee Related
- 2011-09-29 DE DE201112100054 patent/DE122011100054I1/de active Pending
- 2011-09-29 DE DE201112100053 patent/DE122011100053I1/de active Pending
- 2011-10-12 US US13/271,810 patent/US20120029437A1/en not_active Abandoned
- 2011-10-12 US US13/271,839 patent/US9138471B2/en not_active Expired - Fee Related
-
2015
- 2015-04-16 JP JP2015084294A patent/JP6211555B2/ja not_active Expired - Fee Related
-
2017
- 2017-07-10 JP JP2017134258A patent/JP2017186367A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
PT1361890E (pt) | 2011-06-07 |
JP2004532830A (ja) | 2004-10-28 |
JP2015134819A (ja) | 2015-07-27 |
EP2281573A2 (de) | 2011-02-09 |
US20120029437A1 (en) | 2012-02-02 |
EP1361890B1 (de) | 2011-03-30 |
DK1361890T3 (da) | 2011-06-27 |
JP2012046522A (ja) | 2012-03-08 |
ATE503493T1 (de) | 2011-04-15 |
WO2002074336A2 (en) | 2002-09-26 |
US20070237788A1 (en) | 2007-10-11 |
JP6076592B2 (ja) | 2017-02-08 |
US8557251B2 (en) | 2013-10-15 |
US20120039933A1 (en) | 2012-02-16 |
JP5960380B2 (ja) | 2016-08-02 |
EP2269639B1 (de) | 2018-11-28 |
DE122011100054I1 (de) | 2012-03-15 |
CY1111553T1 (el) | 2015-08-05 |
JP2017186367A (ja) | 2017-10-12 |
JP2009173664A (ja) | 2009-08-06 |
US20040071734A1 (en) | 2004-04-15 |
WO2002074336A3 (en) | 2003-08-14 |
US9138471B2 (en) | 2015-09-22 |
JP5208347B2 (ja) | 2013-06-12 |
JP6211555B2 (ja) | 2017-10-11 |
EP2269639A3 (de) | 2011-12-07 |
AU2002254901A1 (en) | 2002-10-03 |
EP2281573A3 (de) | 2011-12-07 |
DE60239594D1 (de) | 2011-05-12 |
EP1361890A2 (de) | 2003-11-19 |
CA2438942A1 (en) | 2002-09-26 |
EP2269639A2 (de) | 2011-01-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE122011100053I1 (de) | Influenza vakzinzusammensetzungen zur intradermaler verabreichung. | |
MY126588A (en) | Intranasal influenza virus vaccine | |
DE602005025342D1 (de) | Impfstoffzusammensetzungen mit virosomen und einem saponin-adjuvans | |
CY1112879T1 (el) | Συνθεση εμβολιου | |
WO2002087494A3 (en) | Novel vaccine | |
WO2002028422A3 (en) | Split enveloped virus preparation for intranasal delivery | |
NO20015073D0 (no) | Vaksiner | |
MXPA05009580A (es) | Vacuna contra el virus de la influenza. | |
DE60039198D1 (de) | Adjuvanszusammensetzungen zur Erhöhung der Immunantwort bezüglich Polynukleotid-basierenden Impfstoffen | |
NO20023829D0 (no) | Proteosom influensavaksine | |
CA2448208A1 (en) | Influenza vaccine composition | |
ATE527281T1 (de) | Impfstoffe gegen aids umfassend cmv/r nucleinsäurekonstrukte | |
CR11307A (es) | Vacunas | |
WO2008054535A3 (en) | Novel influenza m2 vaccines | |
BRPI0606614A2 (pt) | peptìdeos para distribuição de vacinas na mucosa | |
ATE416788T1 (de) | Verwendung von pflanzen-öl-körper in impfstoffverabreichungsysteme | |
EA201070014A1 (ru) | Внутрикожная вакцина против гриппа | |
WO2002030458A8 (en) | Yersinia adhesion protein as vaccine adjuvant | |
DK1490100T3 (da) | Kombinerede DNA/proteinvaccinepræparater |