MX342716B - Vacunas para su uso en la profilaxis y tratamiento de la enfermedad del virus de influenza. - Google Patents
Vacunas para su uso en la profilaxis y tratamiento de la enfermedad del virus de influenza.Info
- Publication number
- MX342716B MX342716B MX2012009581A MX2012009581A MX342716B MX 342716 B MX342716 B MX 342716B MX 2012009581 A MX2012009581 A MX 2012009581A MX 2012009581 A MX2012009581 A MX 2012009581A MX 342716 B MX342716 B MX 342716B
- Authority
- MX
- Mexico
- Prior art keywords
- vaccines
- influenza virus
- prophylaxis
- treatment
- virus disease
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/11—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6012—Haptens, e.g. di- or trinitrophenyl (DNP, TNP)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a una composición inmunogénica capaz de inducir anticuerpos que tienen reactividad cruzada entre subtipos de hemaglutinina (HA), en donde la composición inmunogénica comprende (a) un polipépitdo central inmunogénico, (b) un polipéptido de gripe (c) un virus que expresa un polipéptido central inmunogénico, (d) un virus que expresa un polipéptido de gripe, (e) un virus que comprende un polipéptido central inmunogénico, (f) un virus que comprende un polipéptido de gripe, (g) una partícula similar a virus que comprende un polipéptido central inmunogénico, o (h) una partícula similar a virus que comprende una partícula similar de gripe, y un portador farmacéuticamente aceptable, y en donde (A) el polipéptido central inmunogénico comprende la SEQ ID NO: 6.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30589810P | 2010-02-18 | 2010-02-18 | |
US12/788,103 US8673314B2 (en) | 2009-05-26 | 2010-05-26 | Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof |
US35416010P | 2010-06-11 | 2010-06-11 | |
US38508310P | 2010-09-21 | 2010-09-21 | |
PCT/US2011/025467 WO2011103453A2 (en) | 2010-02-18 | 2011-02-18 | Vaccines for use in the prophylaxis and treatment of influenza virus disease |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2012009581A MX2012009581A (es) | 2013-01-29 |
MX342716B true MX342716B (es) | 2016-10-11 |
Family
ID=44483593
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012009581A MX342716B (es) | 2010-02-18 | 2011-02-18 | Vacunas para su uso en la profilaxis y tratamiento de la enfermedad del virus de influenza. |
Country Status (10)
Country | Link |
---|---|
US (1) | US9701723B2 (es) |
EP (1) | EP2536425B1 (es) |
JP (3) | JP2013520172A (es) |
KR (1) | KR20120132506A (es) |
CN (1) | CN102939096B (es) |
AU (1) | AU2011217903B2 (es) |
BR (1) | BR112012020839A2 (es) |
CA (1) | CA2790380A1 (es) |
MX (1) | MX342716B (es) |
WO (1) | WO2011103453A2 (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
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CA2787099A1 (en) | 2009-03-30 | 2010-10-14 | Anice C. Lowen | Influenza virus hemagglutinin polypeptides containing stem domains, vaccines and uses thereof |
US8673314B2 (en) | 2009-05-26 | 2014-03-18 | Mount Sinai School Of Medicine | Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof |
KR20120132506A (ko) | 2010-02-18 | 2012-12-05 | 마운트 시나이 스쿨 오브 메디슨 | 인플루엔자 바이러스 질환의 예방 및 치료에 사용되는 백신 |
EP3900740A1 (en) | 2010-03-30 | 2021-10-27 | Icahn School of Medicine at Mount Sinai | Influenza virus vaccines and uses thereof |
EA201490659A1 (ru) | 2011-09-20 | 2014-11-28 | Маунт Синай Скул Оф Медсин | Вакцины против вируса гриппа и их применения |
WO2014099931A1 (en) | 2012-12-18 | 2014-06-26 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccines and uses thereof |
US9908930B2 (en) | 2013-03-14 | 2018-03-06 | Icahn School Of Medicine At Mount Sinai | Antibodies against influenza virus hemagglutinin and uses thereof |
US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
CA2974699A1 (en) | 2015-01-23 | 2016-07-28 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccination regimens |
KR101768600B1 (ko) * | 2015-05-18 | 2017-08-17 | 한국생명공학연구원 | 범용성 개 인플루엔자 바이러스 백신 조성물 |
JP6868763B2 (ja) * | 2016-04-01 | 2021-05-12 | パナソニックIpマネジメント株式会社 | インフルエンザウィルスに結合する抗体 |
BR112018075032A2 (pt) | 2016-06-15 | 2019-03-26 | Icahn School Of Medicine At Mount Sinai | proteínas de hemaglutinina do vírus influenza e seus uso |
US10478488B2 (en) | 2017-10-03 | 2019-11-19 | Southwest Research Institute | Liposomal flu vaccine formulation |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
CA3058652A1 (en) | 2017-04-07 | 2018-10-11 | Icahn School Of Medicine At Mount Sinai | Anti-influenza b virus neuraminidase antibodies and uses thereof |
RU2757013C2 (ru) * | 2017-12-19 | 2021-10-08 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт гриппа имени А.А. Смородинцева" Министерства здравоохранения Российской Федерации | Рекомбинантная противогриппозная вакцина с широким спектром защиты и способ ее получения |
CN108287235B (zh) * | 2018-02-07 | 2021-03-09 | 常州天地人和生物科技有限公司 | 一种高效、稳定的磁性免疫微球的制备和应用 |
CN108329379B (zh) * | 2018-04-08 | 2022-01-28 | 诺华生物科技(武汉)有限责任公司 | H7亚型流感病毒h7n9的普通型/嵌合型病毒样颗粒及制备方法、应用和疫苗 |
CN108840911B (zh) * | 2018-06-09 | 2021-03-30 | 西北农林科技大学 | 新城疫病毒基质蛋白的抗原表位、抗体、鉴定方法和应用 |
BR112021001188A8 (pt) | 2018-07-23 | 2022-12-06 | Japan As Represented By The Director General Of Nat Institute Of Infectious Diseases | Composição que contém vacina contra a influenza |
CN109097341B (zh) * | 2018-08-28 | 2021-09-24 | 青岛农业大学 | 一种同时表达ha和hef的复制缺陷型重组流感病毒 |
CN111363017B (zh) * | 2018-12-25 | 2022-03-15 | 中国科学院微生物研究所 | A型流感病毒核蛋白s69位突变序列及其突变体与应用 |
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-
2011
- 2011-02-18 KR KR1020127024205A patent/KR20120132506A/ko not_active Application Discontinuation
- 2011-02-18 JP JP2012554060A patent/JP2013520172A/ja not_active Withdrawn
- 2011-02-18 CA CA2790380A patent/CA2790380A1/en not_active Abandoned
- 2011-02-18 US US13/579,845 patent/US9701723B2/en active Active
- 2011-02-18 MX MX2012009581A patent/MX342716B/es active IP Right Grant
- 2011-02-18 CN CN201180019658.1A patent/CN102939096B/zh active Active
- 2011-02-18 EP EP11745345.6A patent/EP2536425B1/en active Active
- 2011-02-18 WO PCT/US2011/025467 patent/WO2011103453A2/en active Application Filing
- 2011-02-18 AU AU2011217903A patent/AU2011217903B2/en not_active Ceased
- 2011-02-18 BR BR112012020839A patent/BR112012020839A2/pt not_active Application Discontinuation
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2016
- 2016-05-24 JP JP2016103689A patent/JP2016196472A/ja not_active Withdrawn
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2018
- 2018-07-03 JP JP2018126633A patent/JP2018166515A/ja active Pending
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US20130209499A1 (en) | 2013-08-15 |
AU2011217903B2 (en) | 2017-03-02 |
US20170114103A9 (en) | 2017-04-27 |
AU2011217903A1 (en) | 2012-09-13 |
CN102939096A (zh) | 2013-02-20 |
CA2790380A1 (en) | 2011-08-25 |
WO2011103453A2 (en) | 2011-08-25 |
MX2012009581A (es) | 2013-01-29 |
EP2536425A2 (en) | 2012-12-26 |
WO2011103453A3 (en) | 2011-12-29 |
EP2536425B1 (en) | 2019-06-19 |
BR112012020839A2 (pt) | 2017-11-21 |
JP2013520172A (ja) | 2013-06-06 |
KR20120132506A (ko) | 2012-12-05 |
CN102939096B (zh) | 2016-03-02 |
US9701723B2 (en) | 2017-07-11 |
JP2018166515A (ja) | 2018-11-01 |
EP2536425A4 (en) | 2014-11-05 |
JP2016196472A (ja) | 2016-11-24 |
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