CL2008001806A1 - Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion. - Google Patents
Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion.Info
- Publication number
- CL2008001806A1 CL2008001806A1 CL200801806A CL2008001806A CL2008001806A1 CL 2008001806 A1 CL2008001806 A1 CL 2008001806A1 CL 200801806 A CL200801806 A CL 200801806A CL 2008001806 A CL2008001806 A CL 2008001806A CL 2008001806 A1 CL2008001806 A1 CL 2008001806A1
- Authority
- CL
- Chile
- Prior art keywords
- elaboration
- vaccine
- adjuster
- antigen
- oil
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 239000000839 emulsion Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16171—Demonstrated in vivo effect
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93657107P | 2007-06-20 | 2007-06-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2008001806A1 true CL2008001806A1 (es) | 2008-09-05 |
Family
ID=39720537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200801806A CL2008001806A1 (es) | 2007-06-20 | 2008-06-18 | Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion. |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US8980288B2 (es) |
| EP (1) | EP2164510B1 (es) |
| JP (2) | JP5457340B2 (es) |
| KR (1) | KR101569218B1 (es) |
| CN (2) | CN105148268A (es) |
| AR (1) | AR067087A1 (es) |
| AU (1) | AU2008265745B2 (es) |
| BR (1) | BRPI0812856A2 (es) |
| CA (1) | CA2692098C (es) |
| CL (1) | CL2008001806A1 (es) |
| CO (1) | CO6251273A2 (es) |
| CY (1) | CY1114451T1 (es) |
| DK (1) | DK2164510T3 (es) |
| ES (1) | ES2429296T3 (es) |
| HK (1) | HK1218717A1 (es) |
| HR (1) | HRP20130939T1 (es) |
| ME (1) | ME01527B (es) |
| MX (1) | MX2009014070A (es) |
| NZ (1) | NZ582132A (es) |
| PL (1) | PL2164510T3 (es) |
| PT (1) | PT2164510E (es) |
| RS (1) | RS52947B (es) |
| SI (1) | SI2164510T1 (es) |
| TW (1) | TWI507214B (es) |
| WO (1) | WO2008157659A1 (es) |
| ZA (1) | ZA200909173B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CL2008001806A1 (es) * | 2007-06-20 | 2008-09-05 | Wyeth Corp | Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion. |
| CN104001170B (zh) | 2008-06-27 | 2016-08-24 | 硕腾有限责任公司 | 新颖的佐剂组合物 |
| WO2010114169A1 (en) * | 2009-03-31 | 2010-10-07 | Japan As Represented By The Director-General Of National Institute Of Infectious Diseases | Method for prophylaxis of influenza using vaccine for intranasal administration |
| DE112011100387B4 (de) | 2010-01-29 | 2022-07-14 | Donaldson Company, Inc. | Wasserabscheider-Aufbau zur Verwendung mit einem Luftfilter, Motorluftstrom-Einlassanordnung, Fahrzeug und Verfahren |
| CN101829323A (zh) * | 2010-04-28 | 2010-09-15 | 洛阳普莱柯生物工程有限公司 | 一种禽用油乳剂疫苗及其制备方法 |
| US20140113817A1 (en) | 2011-04-12 | 2014-04-24 | Unaio Brasiliense De Educaco E Cultura-Ubec | Peptides with antimicrobial activity, drug compositions for the treatment and prophylaxis of animals, compositions for the treatment and prophylaxis of plants, uses of said peptides, and uses of paenibacillus elgil ourofinensis extract |
| NZ757210A (en) | 2013-09-19 | 2022-12-23 | Zoetis Services Llc | Oil-based adjuvants |
| MX2016007356A (es) * | 2013-12-06 | 2016-10-03 | Advanced Bionutrition Corp | Composicion para administracion oral de agentes bioactivos. |
| LT3244920T (lt) | 2015-01-16 | 2023-08-25 | Zoetis Services Llc | Snukio ir nagų ligos vakcina |
| GB201506948D0 (en) * | 2015-04-23 | 2015-06-10 | Croda Int Plc | Emulsions for injectable formulations |
| CN106177939B (zh) * | 2015-06-01 | 2021-01-19 | 普莱柯生物工程股份有限公司 | 一种疫苗用佐剂及其应用 |
| CN106344920B (zh) * | 2015-07-16 | 2020-11-27 | 普莱柯生物工程股份有限公司 | 一种疫苗用佐剂及其应用 |
| CN107281482B (zh) * | 2016-04-05 | 2021-06-11 | 普莱柯生物工程股份有限公司 | 一种免疫佐剂组合物及其制备方法 |
| US11351249B2 (en) * | 2018-03-13 | 2022-06-07 | Capsular Technologies Pty Ltd | Vaccine compositions comprising a water-in-oil emulsion, immunogen-loaded hydrogel particles, and cationic polymer |
| CN110404065B (zh) * | 2018-04-27 | 2023-06-16 | 洛阳赛威生物科技有限公司 | 一种猪用佐剂组合物及其制备方法 |
| CA3106341A1 (en) * | 2018-07-13 | 2020-01-16 | Biomune Company | New vaccines against avian reoviruses |
| WO2020023950A1 (en) | 2018-07-27 | 2020-01-30 | Research Development Foundation | Chimeric immunogenic polypeptides |
| CN114306585A (zh) * | 2021-12-30 | 2022-04-12 | 广西壮族自治区水产科学研究院 | 一种鱼类高纯度抗原乳剂的制备方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3639577A (en) * | 1968-02-23 | 1972-02-01 | Haver Lockhart Lab Inc | Injectable adjuvant,method of preparing same and compositions including such adjuvant |
| NZ221306A (en) * | 1986-08-15 | 1990-02-26 | Commw Scient Ind Res Org | 2-component immunoadjuvant comprising a mycobacterial free immunoadjuvant oil and a polycationic polyelectrolyte immunoadjuvant and vaccines thereof |
| ES2037072T3 (es) * | 1986-12-19 | 1993-06-16 | Duphar International Research B.V | Suspension coadyuvante estabilizada que comprende bromuro de dimetil-dioctadecil-amonio. |
| US5951988A (en) * | 1993-03-30 | 1999-09-14 | University Of Saskatchewan | Adjuvant formulation with enhanced immunogenic activity, and related compositions and methods |
| BE1008977A5 (fr) * | 1994-12-27 | 1996-10-01 | Solvay | Adjuvants pour vaccins. |
| US5744137A (en) * | 1995-02-06 | 1998-04-28 | The United States Of America As Represented By The Secretary Of The Agriculture | Oil emulsion vaccines prepared with animal, vegetable, and synthetic oils using a mixture of nonionic surfactants |
| JP4918188B2 (ja) * | 1997-12-16 | 2012-04-18 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | サブミクロンの水中油型エマルジョンと合わせた微粒子の使用 |
| FR2775601B1 (fr) * | 1998-03-03 | 2001-09-21 | Merial Sas | Vaccins vivants recombines et adjuves |
| FR2776928B1 (fr) * | 1998-04-03 | 2000-06-23 | Merial Sas | Vaccins adn adjuves |
| WO2001089559A2 (en) * | 2000-05-24 | 2001-11-29 | Merial | Porcine reproductive and respiratory syndrome virus (prrsv) recombinant avipoxvirus vaccine |
| FR2810888B1 (fr) * | 2000-06-29 | 2004-07-30 | Merial Sas | Vaccin contre la fievre aphteuse |
| US6585978B1 (en) * | 2000-09-09 | 2003-07-01 | Akzo Nobel | EIA vaccine and diagnostic |
| US7018638B2 (en) * | 2000-12-19 | 2006-03-28 | Wyeth | Mycoplasma hyopneumoniae bacterin vaccine |
| US6676958B2 (en) * | 2001-06-19 | 2004-01-13 | Advanced Bioadjuvants, Llc | Adjuvant composition for mucosal and injection delivered vaccines |
| US20030129161A1 (en) * | 2001-09-17 | 2003-07-10 | Hsien-Jue Chu | Interleukin-12 as a veterinary vaccine adjuvant |
| JP3812814B2 (ja) * | 2001-10-19 | 2006-08-23 | 株式会社微生物化学研究所 | 動物用多価オイルアジュバントワクチン |
| US7862821B2 (en) * | 2006-06-01 | 2011-01-04 | Merial Limited | Recombinant vaccine against bluetongue virus |
| CL2008001806A1 (es) * | 2007-06-20 | 2008-09-05 | Wyeth Corp | Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion. |
-
2008
- 2008-06-18 CL CL200801806A patent/CL2008001806A1/es unknown
- 2008-06-19 BR BRPI0812856-1A2A patent/BRPI0812856A2/pt not_active IP Right Cessation
- 2008-06-19 WO PCT/US2008/067433 patent/WO2008157659A1/en active Application Filing
- 2008-06-19 AU AU2008265745A patent/AU2008265745B2/en active Active
- 2008-06-19 MX MX2009014070A patent/MX2009014070A/es active IP Right Grant
- 2008-06-19 DK DK08771428.3T patent/DK2164510T3/da active
- 2008-06-19 PL PL08771428T patent/PL2164510T3/pl unknown
- 2008-06-19 EP EP08771428.3A patent/EP2164510B1/en active Active
- 2008-06-19 JP JP2010513396A patent/JP5457340B2/ja not_active Expired - Fee Related
- 2008-06-19 ME MEP-2013-101A patent/ME01527B/me unknown
- 2008-06-19 PT PT87714283T patent/PT2164510E/pt unknown
- 2008-06-19 RS RS20130408A patent/RS52947B/en unknown
- 2008-06-19 NZ NZ582132A patent/NZ582132A/en not_active IP Right Cessation
- 2008-06-19 CA CA2692098A patent/CA2692098C/en not_active Expired - Fee Related
- 2008-06-19 US US12/142,160 patent/US8980288B2/en active Active
- 2008-06-19 KR KR1020107001106A patent/KR101569218B1/ko not_active IP Right Cessation
- 2008-06-19 SI SI200831038T patent/SI2164510T1/sl unknown
- 2008-06-19 CN CN201510450651.5A patent/CN105148268A/zh active Pending
- 2008-06-19 CN CN200880024112A patent/CN101790378A/zh active Pending
- 2008-06-19 ES ES08771428T patent/ES2429296T3/es active Active
- 2008-06-20 AR ARP080102641A patent/AR067087A1/es not_active Application Discontinuation
- 2008-06-20 TW TW097123236A patent/TWI507214B/zh not_active IP Right Cessation
-
2009
- 2009-12-17 CO CO09144676A patent/CO6251273A2/es not_active Application Discontinuation
- 2009-12-22 ZA ZA200909173A patent/ZA200909173B/xx unknown
-
2010
- 2010-11-09 HK HK16106725.1A patent/HK1218717A1/zh unknown
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2013
- 2013-10-03 CY CY20131100855T patent/CY1114451T1/el unknown
- 2013-10-07 HR HRP20130939AT patent/HRP20130939T1/hr unknown
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2014
- 2014-01-09 JP JP2014002096A patent/JP5802285B2/ja not_active Expired - Fee Related
-
2015
- 2015-02-10 US US14/618,628 patent/US9545439B2/en active Active
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