HRP20090516T1 - Formulation of a thienopyridine platelet aggregation inhibitor - Google Patents

Formulation of a thienopyridine platelet aggregation inhibitor

Info

Publication number
HRP20090516T1
HRP20090516T1 HR20090516T HRP20090516T HRP20090516T1 HR P20090516 T1 HRP20090516 T1 HR P20090516T1 HR 20090516 T HR20090516 T HR 20090516T HR P20090516 T HRP20090516 T HR P20090516T HR P20090516 T1 HRP20090516 T1 HR P20090516T1
Authority
HR
Croatia
Prior art keywords
formulation
platelet aggregation
aggregation inhibitor
thienopyridine
thienopyridine platelet
Prior art date
Application number
HR20090516T
Other languages
English (en)
Croatian (hr)
Inventor
Brian Dziennik David
Beth Edelman Tamara
Lloyd Oren Peter
Louis Ternik Robert
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37198935&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20090516(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of HRP20090516T1 publication Critical patent/HRP20090516T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HR20090516T 2005-06-10 2009-09-25 Formulation of a thienopyridine platelet aggregation inhibitor HRP20090516T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68918305P 2005-06-10 2005-06-10
PCT/US2006/021860 WO2006135605A2 (en) 2005-06-10 2006-06-06 Formulation of a thienopyridine platelet aggregation inhibitor

Publications (1)

Publication Number Publication Date
HRP20090516T1 true HRP20090516T1 (en) 2009-10-31

Family

ID=37198935

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20090516T HRP20090516T1 (en) 2005-06-10 2009-09-25 Formulation of a thienopyridine platelet aggregation inhibitor

Country Status (35)

Country Link
US (1) US20080176893A1 (no)
EP (1) EP1896019B1 (no)
JP (1) JP2008543755A (no)
KR (2) KR20100076050A (no)
CN (1) CN101193633B (no)
AR (1) AR054283A1 (no)
AT (1) ATE441413T1 (no)
AU (1) AU2006258102B2 (no)
BR (1) BRPI0611350B8 (no)
CA (1) CA2611668C (no)
CY (1) CY1109502T1 (no)
DE (1) DE602006008942D1 (no)
DK (1) DK1896019T3 (no)
DO (1) DOP2006000126A (no)
EA (1) EA011693B1 (no)
EC (1) ECSP077984A (no)
ES (1) ES2330373T3 (no)
HK (1) HK1116422A1 (no)
HR (1) HRP20090516T1 (no)
IL (1) IL187830A0 (no)
MA (1) MA29688B1 (no)
MX (1) MX2007015431A (no)
MY (1) MY151038A (no)
NO (1) NO20076317L (no)
NZ (1) NZ564003A (no)
PE (1) PE20070320A1 (no)
PL (1) PL1896019T3 (no)
PT (1) PT1896019E (no)
RS (1) RS51194B (no)
SI (1) SI1896019T1 (no)
TN (1) TNSN07466A1 (no)
TW (1) TWI318571B (no)
UA (1) UA91051C2 (no)
WO (1) WO2006135605A2 (no)
ZA (1) ZA200710697B (no)

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JP2010512182A (ja) * 2006-12-07 2010-04-22 イーライ リリー アンド カンパニー プラスグレルのための製品
BRPI0719529B8 (pt) * 2006-12-07 2021-05-25 Daiichi Sankyo Co Ltd método para produzir uma preparação sólida
BRPI0719393B8 (pt) * 2006-12-07 2021-05-25 Daiichi Sankyo Co Ltd composição farmacêutica
US20100280064A1 (en) * 2006-12-07 2010-11-04 Tomoyuki Watanabe Pharmaceutical composition having improved storage stability
JP5289975B2 (ja) * 2006-12-07 2013-09-11 第一三共株式会社 マンニトール又は乳糖を含有する固形製剤
US20090291138A1 (en) * 2006-12-07 2009-11-26 Daiichi Sankyo Company, Limited Film-coated preparation having improved stability
WO2008108291A1 (ja) * 2007-03-02 2008-09-12 Daiichi Sankyo Company, Limited 高純度のプラスグレル塩酸塩の製造方法
KR20160033792A (ko) 2007-04-27 2016-03-28 사이덱스 파마슈티칼스, 인크. 클로피도그렐 및 설포알킬 에테르 사이클로덱스트린을 함유하는 제형 및 사용 방법
GB2450117A (en) * 2007-06-13 2008-12-17 Reckitt Benckiser Healthcare A water- and oxygen-occlusive blister tablet pack
DE112009000268T5 (de) 2008-02-06 2011-06-01 Helm Ag Prasugrel-Salze mit verbesserten Eigenschaften
EP2107061A1 (en) * 2008-04-02 2009-10-07 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of optically enriched clopidogrel
ATE482961T1 (de) 2008-04-25 2010-10-15 Sandoz Ag Hydrogensulfat von 2-acetoxy-5-(a- cyclopropylcarbonyl-2-fluorbenzyl)-4,5,6,7- tetrahydrothienoä3,2-cüpyridin und dessen zubereitung
EP2398468B1 (en) 2009-02-17 2016-11-30 KRKA, D.D., Novo Mesto Pharmaceutical compositions comprising prasugrel base or its pharmaceutically acceptable acid addition salts and processes for their preparation
EP2429291B1 (en) 2009-05-13 2016-07-06 Cydex Pharmaceuticals, Inc. Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same
DE102009036646A1 (de) 2009-08-07 2011-02-10 Ratiopharm Gmbh Prasugrel in nicht-kristalliner Form und pharmazeutische Zusammensetzung davon
WO2011052499A1 (ja) * 2009-10-28 2011-05-05 第一三共株式会社 貯蔵安定性が改善された医薬組成物
JP2013032289A (ja) * 2009-10-28 2013-02-14 Daiichi Sankyo Co Ltd ワックス安定製剤
WO2011092720A2 (en) * 2010-02-01 2011-08-04 Msn Laboratories Limited Pharmaceutical composition of prasugrel and its pharmaceutically acceptable salts
TR201007926A1 (tr) 2010-07-19 2012-02-21 Sanovel İlaç San.Ve Ti̇c.A.Ş. Prasugrel tablet formülasyonları.
TR201005900A1 (tr) 2010-07-19 2012-02-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Geliştirilmiş stabiliteye sahip prasugrel granülleri.
EP2409685A3 (en) 2010-07-19 2012-02-01 Sanovel Ilac Sanayi ve Ticaret A.S. Orally-disintegrating formulations of prasugrel
TR201006802A1 (tr) * 2010-08-17 2012-03-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Prasugrelin oral yolla dağılan formülasyonları.
CZ2011872A3 (cs) 2011-12-22 2013-07-03 Zentiva, K.S. Farmaceutická formulace prasugrelu hydrobromidu
US8603537B2 (en) 2012-04-02 2013-12-10 Egis Pharmaceuticals Plc Prasugrel containing quickly released stable oral pharmaceutical compositions
WO2014060560A1 (en) 2012-10-19 2014-04-24 Sanovel Ilac Sanayi Ve Ticaret A.S. Solid oral formulations of prasugrel
WO2014060554A1 (en) 2012-10-19 2014-04-24 Sanovel Ilac Sanayi Ve Ticaret A.S. Prasugrel formulations
CN102993210A (zh) * 2012-12-19 2013-03-27 苏春华 一种吡啶并噻吩的新化合物
EP2979693A1 (en) 2014-08-01 2016-02-03 Zaklady Farmaceutyczne Polpharma SA Pharmaceutical composition comprising prasugrel or pharmaceutically acceptable salt thereof and process for its preparation
WO2016122421A1 (en) 2015-01-29 2016-08-04 Pharmactive Ilaç Sanayi Ve Ticaret A.Ş. Stable pharmaceutical compositions containing prasugrel base
EP3158993A1 (en) 2015-10-22 2017-04-26 Zaklady Farmaceutyczne Polpharma SA Process for preparing a tablet comprising prasugrel or pharmaceutically acceptable salt thereof
CN107304216A (zh) * 2016-04-20 2017-10-31 陕西合成药业股份有限公司 噻吩吡啶类衍生物及其制备方法和用途
HU231079B1 (hu) 2016-06-23 2020-06-29 Richter Gedeon Nyrt. Eljárás nagytisztaságú Prasugrel előállítására bromopentil szennyezés eltávolításával
GR1009230B (el) 2016-10-12 2018-02-22 Φαρματεν Αβεε Φαρμακευτικο σκευασμα που περιλαμβανει βεσυλικη πρασουγρελη

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* Cited by examiner, † Cited by third party
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FI101150B (fi) * 1991-09-09 1998-04-30 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi
JP4001199B2 (ja) * 2000-07-06 2007-10-31 第一三共株式会社 ヒドロピリジン誘導体酸付加塩
KR20030014294A (ko) * 2000-07-06 2003-02-15 상꾜 가부시키가이샤 히드로피리딘 유도체 산부가염
EP1243524A3 (en) * 2001-03-16 2004-04-07 Pfizer Products Inc. Pharmaceutical kit for oxygen-sensitive drugs
JP4394873B2 (ja) * 2001-12-19 2010-01-06 武田薬品工業株式会社 酸素に不安定な化合物を含有する固形組成物およびその安定化方法
SI21302A (sl) * 2002-10-11 2004-04-30 LEK farmacevtska dru�ba d.d. Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino
US20050020554A1 (en) * 2003-06-06 2005-01-27 Ahmed Salah U. Stability of hormone formulations
RS20060081A (en) * 2003-08-05 2008-06-05 Zentiva A.S., Methods for the stabilization of atorvastatin

Also Published As

Publication number Publication date
WO2006135605A3 (en) 2007-04-12
AU2006258102B2 (en) 2011-09-15
MA29688B1 (fr) 2008-08-01
RS51194B (sr) 2010-10-31
JP2008543755A (ja) 2008-12-04
CA2611668A1 (en) 2006-12-21
EA011693B1 (ru) 2009-04-28
US20080176893A1 (en) 2008-07-24
UA91051C2 (ru) 2010-06-25
ES2330373T3 (es) 2009-12-09
DOP2006000126A (es) 2006-12-15
DE602006008942D1 (en) 2009-10-15
AR054283A1 (es) 2007-06-13
PE20070320A1 (es) 2007-05-12
BRPI0611350B8 (pt) 2021-05-25
ATE441413T1 (de) 2009-09-15
TWI318571B (en) 2009-12-21
CN101193633A (zh) 2008-06-04
BRPI0611350B1 (pt) 2020-09-15
CA2611668C (en) 2013-10-15
PL1896019T3 (pl) 2010-01-29
WO2006135605A2 (en) 2006-12-21
EP1896019A2 (en) 2008-03-12
TNSN07466A1 (en) 2009-03-17
SI1896019T1 (sl) 2010-01-29
KR20080008413A (ko) 2008-01-23
ECSP077984A (es) 2008-01-23
AU2006258102A1 (en) 2006-12-21
MY151038A (en) 2014-03-31
PT1896019E (pt) 2009-11-19
NZ564003A (en) 2011-07-29
KR20100076050A (ko) 2010-07-05
DK1896019T3 (da) 2009-10-26
ZA200710697B (en) 2009-08-26
MX2007015431A (es) 2008-02-21
CN101193633B (zh) 2011-12-14
CY1109502T1 (el) 2014-08-13
IL187830A0 (en) 2008-04-13
NO20076317L (no) 2008-02-29
EP1896019B1 (en) 2009-09-02
BRPI0611350A2 (pt) 2010-12-07
HK1116422A1 (en) 2008-12-24
TW200718420A (en) 2007-05-16
EA200702670A1 (ru) 2008-04-28

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