HRP20050378A2 - Purine compounds and use thereof as cannabinoid receptor ligands - Google Patents

Purine compounds and use thereof as cannabinoid receptor ligands

Info

Publication number
HRP20050378A2
HRP20050378A2 HR20050378A HRP20050378A HRP20050378A2 HR P20050378 A2 HRP20050378 A2 HR P20050378A2 HR 20050378 A HR20050378 A HR 20050378A HR P20050378 A HRP20050378 A HR P20050378A HR P20050378 A2 HRP20050378 A2 HR P20050378A2
Authority
HR
Croatia
Prior art keywords
alkyl
alkylamino
partially
aryl
heteroaryl
Prior art date
Application number
HR20050378A
Other languages
English (en)
Croatian (hr)
Inventor
Andrew Griffith David
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of HRP20050378A2 publication Critical patent/HRP20050378A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

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  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
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  • Hematology (AREA)
  • Endocrinology (AREA)
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  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
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  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Child & Adolescent Psychology (AREA)
HR20050378A 2002-10-28 2003-10-21 Purine compounds and use thereof as cannabinoid receptor ligands HRP20050378A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42187402P 2002-10-28 2002-10-28
PCT/IB2003/004619 WO2004037823A1 (en) 2002-10-28 2003-10-21 Purine compounds and uses thereof as cannabinoid receptor ligands

Publications (1)

Publication Number Publication Date
HRP20050378A2 true HRP20050378A2 (en) 2005-12-31

Family

ID=32176739

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20050378A HRP20050378A2 (en) 2002-10-28 2003-10-21 Purine compounds and use thereof as cannabinoid receptor ligands

Country Status (44)

Country Link
US (2) US7129239B2 (enExample)
EP (1) EP1558615B8 (enExample)
JP (2) JP3954618B2 (enExample)
KR (1) KR100674560B1 (enExample)
CN (3) CN1955181A (enExample)
AP (1) AP1916A (enExample)
AR (1) AR041835A1 (enExample)
AT (1) ATE371658T1 (enExample)
AU (1) AU2003269368B2 (enExample)
BR (1) BR0314918A (enExample)
CA (1) CA2503900C (enExample)
CO (1) CO5560546A2 (enExample)
CR (1) CR7812A (enExample)
CU (1) CU23535A3 (enExample)
CY (1) CY1107505T1 (enExample)
DE (1) DE60316012T2 (enExample)
DK (1) DK1558615T3 (enExample)
DO (1) DOP2003000742A (enExample)
EA (1) EA008176B1 (enExample)
EC (1) ECSP055767A (enExample)
EG (1) EG24662A (enExample)
ES (1) ES2291669T3 (enExample)
GE (1) GEP20084325B (enExample)
GT (1) GT200300232A (enExample)
HR (1) HRP20050378A2 (enExample)
IS (1) IS2602B (enExample)
MA (1) MA27479A1 (enExample)
MX (1) MXPA05003882A (enExample)
MY (1) MY140010A (enExample)
NL (1) NL1024643C2 (enExample)
NO (1) NO332195B1 (enExample)
NZ (1) NZ539589A (enExample)
OA (1) OA13080A (enExample)
PE (1) PE20040781A1 (enExample)
PL (1) PL376311A1 (enExample)
PT (1) PT1558615E (enExample)
RS (2) RS20050306A (enExample)
SG (1) SG148071A1 (enExample)
TN (1) TNSN05121A1 (enExample)
TW (1) TWI327567B (enExample)
UA (1) UA79507C2 (enExample)
UY (1) UY28044A1 (enExample)
WO (1) WO2004037823A1 (enExample)
ZA (1) ZA200503378B (enExample)

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