HK1090639A1 - Immunosuppressant compounds and compositions - Google Patents
Immunosuppressant compounds and compositionsInfo
- Publication number
- HK1090639A1 HK1090639A1 HK06111345.3A HK06111345A HK1090639A1 HK 1090639 A1 HK1090639 A1 HK 1090639A1 HK 06111345 A HK06111345 A HK 06111345A HK 1090639 A1 HK1090639 A1 HK 1090639A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- compositions
- immunosuppressant compounds
- immunosuppressant
- compounds
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61P17/08—Antiseborrheics
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- A—HUMAN NECESSITIES
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- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Otolaryngology (AREA)
- AIDS & HIV (AREA)
- Obesity (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47193103P | 2003-05-19 | 2003-05-19 | |
US56218304P | 2004-04-14 | 2004-04-14 | |
PCT/US2004/015702 WO2005000833A1 (en) | 2003-05-19 | 2004-05-19 | Immunosuppressant compounds and compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1090639A1 true HK1090639A1 (en) | 2006-12-29 |
Family
ID=33555317
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06111345.3A HK1090639A1 (en) | 2003-05-19 | 2006-10-17 | Immunosuppressant compounds and compositions |
Country Status (14)
Country | Link |
---|---|
US (2) | US7417065B2 (es) |
EP (2) | EP2644195A1 (es) |
JP (1) | JP4944613B2 (es) |
AR (1) | AR044402A1 (es) |
AU (2) | AU2004251146A1 (es) |
BR (1) | BRPI0410439A (es) |
CA (1) | CA2524048C (es) |
CL (1) | CL2004001120A1 (es) |
ES (1) | ES2467160T3 (es) |
HK (1) | HK1090639A1 (es) |
MX (1) | MXPA05012461A (es) |
PE (1) | PE20050158A1 (es) |
TW (1) | TW200505442A (es) |
WO (1) | WO2005000833A1 (es) |
Families Citing this family (111)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY150088A (en) * | 2003-05-19 | 2013-11-29 | Irm Llc | Immunosuppressant compounds and compositions |
AU2004268455B2 (en) * | 2003-08-29 | 2009-12-17 | Ono Pharmaceutical Co., Ltd. | Compound capable of binding S1P receptor and pharmaceutical use thereof |
GB0500020D0 (en) | 2005-01-04 | 2005-02-09 | Novartis Ag | Organic compounds |
TW200538433A (en) | 2004-02-24 | 2005-12-01 | Irm Llc | Immunosuppressant compounds and compositiions |
AU2005272619A1 (en) | 2004-08-13 | 2006-02-23 | Praecis Pharmaceuticals, Inc. | Methods and compositions for modulating sphingosine-1-phosphate (SIP) receptor activity |
KR20070085465A (ko) | 2004-11-29 | 2007-08-27 | 노파르티스 아게 | S1p 수용체 효능제의 투여 용법 |
CA2595960A1 (en) * | 2005-02-08 | 2006-08-17 | Novartis Ag | Antilymphocyte antibody induction by combination of an s1p receptor agonist/modulator and of immunosuppressive drugs |
GB0504544D0 (en) | 2005-03-04 | 2005-04-13 | Novartis Ag | Organic compounds |
WO2006104668A2 (en) * | 2005-03-11 | 2006-10-05 | Temple University - Of The Commonwealth System Of Higher Education | Composition and methods for the treatment of proliferative diseases |
KR20070121013A (ko) * | 2005-04-22 | 2007-12-26 | 다이이찌 산쿄 가부시키가이샤 | 헤테로 고리 화합물 |
ATE533485T1 (de) * | 2005-10-31 | 2011-12-15 | Merck Sharp & Dohme | Cetp-inhibitoren |
CA2630714C (en) * | 2005-11-23 | 2014-01-14 | Epix Delaware, Inc. | S1p receptor modulating compounds and use thereof |
US7919519B2 (en) * | 2005-11-23 | 2011-04-05 | Epix Pharmaceuticals Inc. | S1P receptor modulating compounds and use thereof |
TW200806633A (en) * | 2006-03-21 | 2008-02-01 | Epix Pharm Inc | S1P receptor modulating compounds and use thereof |
WO2007129473A1 (ja) * | 2006-05-09 | 2007-11-15 | Daiichi Sankyo Company, Limited | 二環性アリール誘導体 |
JPWO2007129745A1 (ja) | 2006-05-09 | 2009-09-17 | 第一三共株式会社 | ヘテロアリールアミド低級カルボン酸誘導体 |
GB0612721D0 (en) | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
JP2009269819A (ja) * | 2006-08-25 | 2009-11-19 | Asahi Kasei Pharma Kk | アミン化合物 |
MX2009010060A (es) * | 2007-03-21 | 2010-01-20 | Epix Pharm Inc | Compuestos moduladores del receptor de esfingosin-1-fosfato y uso de los mismos. |
EP2188252B1 (en) * | 2007-09-20 | 2011-04-13 | Amgen Inc. | 1-(4-(4-benzylbenzamido)-benzyl)azetidine-3-carboxylic acid derivatives and related compounds as s1p receptor modulators for the treatment of immune disorders |
KR101600098B1 (ko) | 2007-10-12 | 2016-03-04 | 노파르티스 아게 | 스핑고신 1 포스페이트 (s1p) 수용체 조절제를 포함하는 조성물 |
GB0725101D0 (en) * | 2007-12-21 | 2008-01-30 | Glaxo Group Ltd | Compounds |
GB0807910D0 (en) * | 2008-04-30 | 2008-06-04 | Glaxo Group Ltd | Compounds |
TW201000099A (en) * | 2008-06-20 | 2010-01-01 | Amgen Inc | S1P1 receptor agonists and use thereof |
NZ590377A (en) | 2008-07-15 | 2011-11-25 | Sanofi Aventis | Oxazolopyrimidines as edg-1 receptor agonists |
AU2013209344B2 (en) * | 2008-07-23 | 2015-12-24 | Novartis Ag | Sphingosine 1 phosphate receptor modulators and their use to treat muscle inflammation |
SI2307007T1 (sl) | 2008-07-23 | 2014-11-28 | Novartis Ag | Modulatorji sfingozin 1 fosfatnega receptorja in njihova uporaba za zdravljenje mišičnega vnetja |
NZ590474A (en) | 2008-07-23 | 2012-10-26 | Arena Pharm Inc | SUBSTITUTED 1,2,3,4- TETRAHYDROCYCLOPENTA[b]INDOL-3-YL) ACETIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS |
CN102197038B (zh) | 2008-08-27 | 2016-04-20 | 艾尼纳制药公司 | 用于治疗自身免疫性病症和炎性病症的作为s1p1受体激动剂的经取代的三环酸衍生物 |
JP5578083B2 (ja) | 2008-12-05 | 2014-08-27 | アステラス製薬株式会社 | 2h−クロメン化合物及びその誘導体 |
SI2379069T1 (sl) | 2008-12-22 | 2015-07-31 | Novartis Ag | Režim odmerjanja agonista receptorja S1P |
EP2389377B1 (en) | 2009-01-23 | 2014-07-16 | Bristol-Myers Squibb Company | Substituted oxadiazole derivatives as s1p agonists in the treatment of autoimmune and inflammatory diseases |
CN102361867A (zh) | 2009-01-23 | 2012-02-22 | 百时美施贵宝公司 | 在治疗自身免疫疾病和炎性疾病中作为s1p激动剂的取代的噁二唑衍生物 |
US8389509B2 (en) | 2009-01-23 | 2013-03-05 | Bristol-Myers Squibb Company | Substituted pyrazole compounds |
UA107360C2 (en) | 2009-08-05 | 2014-12-25 | Biogen Idec Inc | Bicyclic aryl sphingosine 1-phosphate analogs |
US8399451B2 (en) | 2009-08-07 | 2013-03-19 | Bristol-Myers Squibb Company | Heterocyclic compounds |
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- 2004-05-19 ES ES04752679.3T patent/ES2467160T3/es not_active Expired - Lifetime
- 2004-05-19 CA CA2524048A patent/CA2524048C/en not_active Expired - Fee Related
- 2004-05-19 AR ARP040101735A patent/AR044402A1/es unknown
- 2004-05-19 WO PCT/US2004/015702 patent/WO2005000833A1/en active Application Filing
- 2004-05-19 EP EP13173514.4A patent/EP2644195A1/en not_active Withdrawn
- 2004-05-19 MX MXPA05012461A patent/MXPA05012461A/es active IP Right Grant
- 2004-05-19 BR BRPI0410439-0A patent/BRPI0410439A/pt not_active IP Right Cessation
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- 2004-05-19 EP EP04752679.3A patent/EP1628967B1/en not_active Expired - Lifetime
- 2004-05-19 TW TW093114152A patent/TW200505442A/zh unknown
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2006
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US7750021B2 (en) | 2010-07-06 |
JP2006528698A (ja) | 2006-12-21 |
EP1628967A4 (en) | 2011-04-27 |
EP2644195A1 (en) | 2013-10-02 |
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BRPI0410439A (pt) | 2006-06-06 |
MXPA05012461A (es) | 2006-02-22 |
CA2524048A1 (en) | 2005-01-06 |
US20090131400A1 (en) | 2009-05-21 |
EP1628967A1 (en) | 2006-03-01 |
CL2004001120A1 (es) | 2005-04-15 |
WO2005000833A1 (en) | 2005-01-06 |
TW200505442A (en) | 2005-02-16 |
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