HK1074217A1 - Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase - Google Patents

Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase

Info

Publication number
HK1074217A1
HK1074217A1 HK05106631A HK05106631A HK1074217A1 HK 1074217 A1 HK1074217 A1 HK 1074217A1 HK 05106631 A HK05106631 A HK 05106631A HK 05106631 A HK05106631 A HK 05106631A HK 1074217 A1 HK1074217 A1 HK 1074217A1
Authority
HK
Hong Kong
Prior art keywords
variants
gdh
pyrroloquinoline quinone
dependent glucose
glucose dehydrogenase
Prior art date
Application number
HK05106631A
Other languages
English (en)
Inventor
Peter Kratzsch
Rainer Schmuck
Daniela Bunk
Zhixin Shao
Detlef Thym
Wolfgang-Reinhold Knappe
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1074217A1 publication Critical patent/HK1074217A1/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK05106631A 2000-10-27 2005-08-02 Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase HK1074217A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00123512 2000-10-27
EP00127294 2000-12-19
PCT/EP2001/012148 WO2002034919A1 (en) 2000-10-27 2001-10-20 Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase

Publications (1)

Publication Number Publication Date
HK1074217A1 true HK1074217A1 (en) 2005-11-04

Family

ID=26071553

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05106631A HK1074217A1 (en) 2000-10-27 2005-08-02 Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase

Country Status (12)

Country Link
US (3) US20030104595A1 (pt)
EP (1) EP1332216B1 (pt)
JP (2) JP3845618B2 (pt)
KR (1) KR100519902B1 (pt)
CN (1) CN1288246C (pt)
AT (1) ATE520777T1 (pt)
AU (2) AU2002215966B2 (pt)
BR (1) BRPI0114962B8 (pt)
CA (1) CA2427029C (pt)
HK (1) HK1074217A1 (pt)
PL (1) PL205561B1 (pt)
WO (1) WO2002034919A1 (pt)

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US7604969B2 (en) 2005-06-20 2009-10-20 Arkray, Inc. Mutant glucose dehydrogenase
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EP2010649B1 (en) 2006-04-13 2017-03-08 Roche Diabetes Care GmbH Improved mutants of pyrroloquinoline quinone dependent soluble glucose dehydrogenase
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EP2465936A1 (en) 2010-12-20 2012-06-20 LEK Pharmaceuticals d.d. Enzymatic synthesis of statins and intermediates thereof
WO2012084194A1 (en) 2010-12-22 2012-06-28 Roche Diagnostics Gmbh Systems and methods to compensate for sources of error during electrochemical testing
CN102559624B (zh) * 2012-03-05 2013-10-16 浙江德清汇宁生物科技有限公司 一种吡咯喹啉醌依赖型葡萄糖脱氢酶的热稳定性突变体及其高通量筛选方法
EP2636750A1 (en) 2012-03-06 2013-09-11 Roche Diagniostics GmbH Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
EP2994536B1 (en) 2013-05-08 2017-06-14 Roche Diabetes Care GmbH Stabilization of enzymes by nicotinic acid
WO2015078899A1 (en) 2013-11-27 2015-06-04 Roche Diagnostics Gmbh Composition comprising up-converting phosphors for detecting an analyte
EP2927319A1 (en) 2014-03-31 2015-10-07 Roche Diagnostics GmbH High load enzyme immobilization by crosslinking
JP6522003B2 (ja) 2014-04-14 2019-05-29 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ フェナジニウムメディエーター
CN106573910B (zh) 2014-08-22 2020-08-28 豪夫迈·罗氏有限公司 氧化还原指示剂
CN105331591B (zh) * 2015-10-29 2020-02-28 英科隆生物技术（杭州）有限公司 PQQ-sGDH突变体、聚核苷酸及葡萄糖检测装置
CN109804240A (zh) 2016-10-05 2019-05-24 豪夫迈·罗氏有限公司 用于多分析物诊断测试元件的检测试剂和电极布置以及其使用方法
CN113234697B (zh) * 2021-04-28 2022-09-02 遵义医科大学珠海校区 一种葡萄糖脱氢酶变体及其制备方法与应用

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Also Published As

Publication number Publication date
CN1578836A (zh) 2005-02-09
US20030104595A1 (en) 2003-06-05
JP2004512047A (ja) 2004-04-22
CN1288246C (zh) 2006-12-06
EP1332216A1 (en) 2003-08-06
WO2002034919A1 (en) 2002-05-02
BR0114962A (pt) 2003-10-28
KR100519902B1 (ko) 2005-10-10
US20040005683A1 (en) 2004-01-08
EP1332216B1 (en) 2011-08-17
JP3845618B2 (ja) 2006-11-15
PL205561B1 (pl) 2010-05-31
BRPI0114962B8 (pt) 2021-07-27
ATE520777T1 (de) 2011-09-15
BRPI0114962B1 (pt) 2016-07-12
PL362548A1 (en) 2004-11-02
KR20030048447A (ko) 2003-06-19
US7132270B2 (en) 2006-11-07
CA2427029C (en) 2010-02-02
US20060148056A1 (en) 2006-07-06
JP3889434B2 (ja) 2007-03-07
AU2002215966B2 (en) 2006-05-04
US7547535B2 (en) 2009-06-16
AU1596602A (en) 2002-05-06
CA2427029A1 (en) 2002-05-02
JP2006314322A (ja) 2006-11-24

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Effective date: 20211019