BR0114962A - Variações da glicose desidrogenase solúvel dependente de pirroloquinolina quinona - Google Patents

Variações da glicose desidrogenase solúvel dependente de pirroloquinolina quinona

Info

Publication number
BR0114962A
BR0114962A BR0114962-8A BR0114962A BR0114962A BR 0114962 A BR0114962 A BR 0114962A BR 0114962 A BR0114962 A BR 0114962A BR 0114962 A BR0114962 A BR 0114962A
Authority
BR
Brazil
Prior art keywords
gdh
pyrroloquinoline
variations
glucose dehydrogenase
soluble glucose
Prior art date
Application number
BR0114962-8A
Other languages
English (en)
Other versions
BRPI0114962B8 (pt
BRPI0114962B1 (pt
Inventor
Peter Kratzsch
Rainer Schmuck
Daniela Bunk
Zhixin Shao
Detlef Thym
Wolfgang-Reinhold Knappe
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR0114962A publication Critical patent/BR0114962A/pt
Publication of BRPI0114962B1 publication Critical patent/BRPI0114962B1/pt
Publication of BRPI0114962B8 publication Critical patent/BRPI0114962B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

"VARIAçõES DA GLICOSE DESIDROGENASE SOLúVEL DEPENDENTE DE PIRROLOQUINOLINA QUINONA". A presente invenção refere-se a variações melhoradas das glicose desidrogenases solúveis (s-GDH) dependentes de pirroloquinolina quinona (PQQ), aos genes que codificam a S-GDH mutada, às proteínas mutantes de S-GDH com maior especificidade ao substrato pela glicose e às diferentes aplicações destas variações da S-GDH, particularmente para a determinação das concentrações de açúcar, especialmente da glicose em uma amostra.
BRPI0114962A 2000-10-27 2001-10-20 mutante de glicose desidrogenase solúvel (s-gdh) dependente de pirroloquinolina quinona (pqq), processo para detecção, determinação ou medição da glicose em uma amostra, e dispositivo para realização do mesmo BRPI0114962B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00123512 2000-10-27
EP00127294 2000-12-19
PCT/EP2001/012148 WO2002034919A1 (en) 2000-10-27 2001-10-20 Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase

Publications (3)

Publication Number Publication Date
BR0114962A true BR0114962A (pt) 2003-10-28
BRPI0114962B1 BRPI0114962B1 (pt) 2016-07-12
BRPI0114962B8 BRPI0114962B8 (pt) 2021-07-27

Family

ID=26071553

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0114962A BRPI0114962B8 (pt) 2000-10-27 2001-10-20 mutante de glicose desidrogenase solúvel (s-gdh) dependente de pirroloquinolina quinona (pqq), processo para detecção, determinação ou medição da glicose em uma amostra, e dispositivo para realização do mesmo

Country Status (12)

Country Link
US (3) US20030104595A1 (pt)
EP (1) EP1332216B1 (pt)
JP (2) JP3845618B2 (pt)
KR (1) KR100519902B1 (pt)
CN (1) CN1288246C (pt)
AT (1) ATE520777T1 (pt)
AU (2) AU1596602A (pt)
BR (1) BRPI0114962B8 (pt)
CA (1) CA2427029C (pt)
HK (1) HK1074217A1 (pt)
PL (1) PL205561B1 (pt)
WO (1) WO2002034919A1 (pt)

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HUE049911T2 (hu) 2006-04-13 2020-11-30 Hoffmann La Roche Pirrolokinolin-kinon-függõ, oldható glükóz-dehidrogenáz javított mutánsai
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EP2927319A1 (en) 2014-03-31 2015-10-07 Roche Diagnostics GmbH High load enzyme immobilization by crosslinking
CN106164054B (zh) 2014-04-14 2019-05-07 豪夫迈·罗氏有限公司 吩嗪介导剂
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Also Published As

Publication number Publication date
PL205561B1 (pl) 2010-05-31
JP3889434B2 (ja) 2007-03-07
JP2004512047A (ja) 2004-04-22
JP2006314322A (ja) 2006-11-24
US20060148056A1 (en) 2006-07-06
US7547535B2 (en) 2009-06-16
EP1332216A1 (en) 2003-08-06
US7132270B2 (en) 2006-11-07
PL362548A1 (en) 2004-11-02
CN1288246C (zh) 2006-12-06
BRPI0114962B8 (pt) 2021-07-27
BRPI0114962B1 (pt) 2016-07-12
AU1596602A (en) 2002-05-06
CN1578836A (zh) 2005-02-09
CA2427029A1 (en) 2002-05-02
WO2002034919A1 (en) 2002-05-02
CA2427029C (en) 2010-02-02
JP3845618B2 (ja) 2006-11-15
ATE520777T1 (de) 2011-09-15
AU2002215966B2 (en) 2006-05-04
US20030104595A1 (en) 2003-06-05
KR100519902B1 (ko) 2005-10-10
HK1074217A1 (en) 2005-11-04
KR20030048447A (ko) 2003-06-19
EP1332216B1 (en) 2011-08-17
US20040005683A1 (en) 2004-01-08

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

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B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 12/07/2016, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 20/10/2001, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 21A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2693 DE 16-08-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.