PL1802748T3 - Termostabilne mutanty dehydrogenazy glukozowej zależnej od pirolochinolinochinonu - Google Patents
Termostabilne mutanty dehydrogenazy glukozowej zależnej od pirolochinolinochinonuInfo
- Publication number
- PL1802748T3 PL1802748T3 PL05792997T PL05792997T PL1802748T3 PL 1802748 T3 PL1802748 T3 PL 1802748T3 PL 05792997 T PL05792997 T PL 05792997T PL 05792997 T PL05792997 T PL 05792997T PL 1802748 T3 PL1802748 T3 PL 1802748T3
- Authority
- PL
- Poland
- Prior art keywords
- gdh
- glucose dehydrogenase
- pyrroloquinoline quinone
- dependent glucose
- thermostable mutants
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04024593 | 2004-10-15 | ||
| EP05792997A EP1802748B1 (en) | 2004-10-15 | 2005-10-14 | Thermostable mutants of pyrroloquinoline quinone dependent glucose dehydrogenase |
| PCT/EP2005/011077 WO2006040172A1 (en) | 2004-10-15 | 2005-10-14 | Thermostable mutants of pyrroloquinoline quinone dependent glucose dehydrogenase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1802748T3 true PL1802748T3 (pl) | 2011-11-30 |
Family
ID=34926995
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10168981T PL2251420T3 (pl) | 2004-10-15 | 2005-10-14 | Termostabilne mutanty dehydrogenazy glukozowej zależnej od pirolochinolinochinonu |
| PL05792997T PL1802748T3 (pl) | 2004-10-15 | 2005-10-14 | Termostabilne mutanty dehydrogenazy glukozowej zależnej od pirolochinolinochinonu |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10168981T PL2251420T3 (pl) | 2004-10-15 | 2005-10-14 | Termostabilne mutanty dehydrogenazy glukozowej zależnej od pirolochinolinochinonu |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7781196B2 (pl) |
| EP (2) | EP2251420B1 (pl) |
| JP (1) | JP4782138B2 (pl) |
| CN (1) | CN101040044B (pl) |
| AT (1) | ATE511538T1 (pl) |
| CA (1) | CA2581226C (pl) |
| ES (2) | ES2366479T3 (pl) |
| HK (1) | HK1111723A1 (pl) |
| PL (2) | PL2251420T3 (pl) |
| WO (1) | WO2006040172A1 (pl) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2251420B1 (en) | 2004-10-15 | 2015-03-04 | Roche Diagnostics GmbH | Thermostable mutants of pyrroloquinoline quinone dependent glucose dehydrogenase |
| FR2948680B1 (fr) * | 2009-07-28 | 2013-10-04 | Centre Nat Rech Scient | Nouveaux mutants de la pqq s-gdh |
| EP2465936A1 (en) | 2010-12-20 | 2012-06-20 | LEK Pharmaceuticals d.d. | Enzymatic synthesis of statins and intermediates thereof |
| CA2822331A1 (en) | 2010-12-20 | 2012-07-19 | Lek Pharmaceuticals D.D. | Enzymatic synthesis of active pharmaceutical ingredient and intermediates thereof |
| CN102559624B (zh) * | 2012-03-05 | 2013-10-16 | 浙江德清汇宁生物科技有限公司 | 一种吡咯喹啉醌依赖型葡萄糖脱氢酶的热稳定性突变体及其高通量筛选方法 |
| WO2015063025A1 (en) | 2013-10-29 | 2015-05-07 | F. Hoffmann-La Roche Ag | Nano-enzyme containers for test elements |
| CN111073866B (zh) * | 2015-10-29 | 2024-03-19 | 英科隆生物技术（杭州）有限公司 | PQQ-sGDH突变体、聚核苷酸及其在葡萄糖检测中的应用 |
| KR20180087329A (ko) | 2015-12-21 | 2018-08-01 | 에프. 호프만-라 로슈 아게 | 알칼리게네스 파에칼리스로부터의 돌연변이체 3-히드록시부티레이트 탈수소효소 뿐만 아니라 이의 관련 방법 및 용도 |
| JP6989528B2 (ja) | 2016-02-09 | 2022-01-05 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | ロドバクター・スフェロイデス（Ｒｈｏｄｏｂａｃｔｅｒ ｓｐｈａｅｒｏｉｄｅｓ）由来の変異型３−ヒドロキシブチレート脱水素酵素及びそれを含む方法 |
| CN110494568B (zh) * | 2017-03-31 | 2024-03-19 | 龟甲万株式会社 | 使用fad依赖性葡糖脱氢酶的连续葡萄糖监测 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3716957A1 (de) | 1987-05-20 | 1988-12-01 | Boehringer Mannheim Gmbh | Expressionsvektor zur regulierbaren expression von fremdgenen in prokaryonten |
| DE4311464A1 (de) | 1993-04-08 | 1994-10-13 | Boehringer Mannheim Gmbh | Verfahren zur kolorimetrischen Bestimmung eines Analyten mit einer PQQ-abhängigen Dehydrogenase |
| DE19639169A1 (de) | 1996-09-24 | 1998-04-02 | Boehringer Mannheim Gmbh | Redoxaktive Verbindungen und deren Anwendung |
| JPH10243786A (ja) | 1997-03-03 | 1998-09-14 | Koji Hayade | 改変型グルコース脱水素酵素 |
| US5997817A (en) | 1997-12-05 | 1999-12-07 | Roche Diagnostics Corporation | Electrochemical biosensor test strip |
| JPH11243949A (ja) | 1998-03-03 | 1999-09-14 | Toyobo Co Ltd | Ｐｑｑを補欠分子族とするグルコースデヒドロゲナーゼおよびその製造方法 |
| JP2000350588A (ja) | 1999-04-08 | 2000-12-19 | Koji Hayade | グルコース脱水素酵素 |
| TWI224136B (en) | 1999-04-30 | 2004-11-21 | Koji Sode | Glucose dehydrogenase |
| CN1288246C (zh) | 2000-10-27 | 2006-12-06 | 霍夫曼-拉罗奇有限公司 | 可溶性吡咯并喹啉醌依赖性葡萄糖脱氢酶变异体 |
| US7476525B2 (en) | 2002-05-27 | 2009-01-13 | Toyo Boseki Kabushiki Kaisha | Modified pyrroloquinoline quinone (PQQ) dependent glucose dehydrogenase with superior substrate specificity and stability |
| JP2004173538A (ja) | 2002-11-25 | 2004-06-24 | Amano Enzyme Inc | ピロロキノリンキノン依存性グルコース脱水素酵素 |
| EP2251420B1 (en) | 2004-10-15 | 2015-03-04 | Roche Diagnostics GmbH | Thermostable mutants of pyrroloquinoline quinone dependent glucose dehydrogenase |
-
2005
- 2005-10-14 EP EP10168981.8A patent/EP2251420B1/en active Active
- 2005-10-14 WO PCT/EP2005/011077 patent/WO2006040172A1/en active Application Filing
- 2005-10-14 EP EP05792997A patent/EP1802748B1/en active Active
- 2005-10-14 US US11/665,437 patent/US7781196B2/en active Active
- 2005-10-14 CN CN200580034780.0A patent/CN101040044B/zh active Active
- 2005-10-14 CA CA2581226A patent/CA2581226C/en active Active
- 2005-10-14 ES ES05792997T patent/ES2366479T3/es active Active
- 2005-10-14 AT AT05792997T patent/ATE511538T1/de not_active IP Right Cessation
- 2005-10-14 ES ES10168981.8T patent/ES2537106T3/es active Active
- 2005-10-14 PL PL10168981T patent/PL2251420T3/pl unknown
- 2005-10-14 JP JP2007533967A patent/JP4782138B2/ja active Active
- 2005-10-14 PL PL05792997T patent/PL1802748T3/pl unknown
-
2008
- 2008-03-06 HK HK08102643.9A patent/HK1111723A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1802748B1 (en) | 2011-06-01 |
| US20090305316A1 (en) | 2009-12-10 |
| CN101040044A (zh) | 2007-09-19 |
| ATE511538T1 (de) | 2011-06-15 |
| US7781196B2 (en) | 2010-08-24 |
| JP2008515400A (ja) | 2008-05-15 |
| JP4782138B2 (ja) | 2011-09-28 |
| CN101040044B (zh) | 2014-06-11 |
| EP1802748A1 (en) | 2007-07-04 |
| CA2581226C (en) | 2011-06-14 |
| WO2006040172A1 (en) | 2006-04-20 |
| ES2366479T3 (es) | 2011-10-20 |
| CA2581226A1 (en) | 2006-04-20 |
| HK1111723A1 (en) | 2008-08-15 |
| ES2537106T3 (es) | 2015-06-02 |
| EP2251420B1 (en) | 2015-03-04 |
| EP2251420A1 (en) | 2010-11-17 |
| PL2251420T3 (pl) | 2015-08-31 |
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