HK1069168A1 - Improved process for preparing benzimidazole-type compounds - Google Patents

Improved process for preparing benzimidazole-type compounds

Info

Publication number
HK1069168A1
HK1069168A1 HK05101607A HK05101607A HK1069168A1 HK 1069168 A1 HK1069168 A1 HK 1069168A1 HK 05101607 A HK05101607 A HK 05101607A HK 05101607 A HK05101607 A HK 05101607A HK 1069168 A1 HK1069168 A1 HK 1069168A1
Authority
HK
Hong Kong
Prior art keywords
improved process
type compounds
benzimidazole
preparing benzimidazole
preparing
Prior art date
Application number
HK05101607A
Other languages
English (en)
Inventor
Rudy Laurent Maria Broeckx
Dirk De Smaele
Stefan Marcel Herman Leurs
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1069168A1 publication Critical patent/HK1069168A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
  • Extraction Or Liquid Replacement (AREA)
HK05101607A 2001-07-16 2005-02-25 Improved process for preparing benzimidazole-type compounds HK1069168A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01202696 2001-07-16
PCT/EP2002/007693 WO2003008406A1 (en) 2001-07-16 2002-07-09 Improved process for preparing benzimidazole-type compounds

Publications (1)

Publication Number Publication Date
HK1069168A1 true HK1069168A1 (en) 2005-05-13

Family

ID=8180641

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05101607A HK1069168A1 (en) 2001-07-16 2005-02-25 Improved process for preparing benzimidazole-type compounds

Country Status (23)

Country Link
US (1) US6919459B2 (ru)
EP (1) EP1409478B1 (ru)
JP (1) JP4320250B2 (ru)
KR (1) KR100914175B1 (ru)
CN (1) CN1235899C (ru)
AT (1) ATE321758T1 (ru)
AU (1) AU2002321204B2 (ru)
BR (1) BRPI0211101B8 (ru)
CA (1) CA2450433C (ru)
CZ (1) CZ304526B6 (ru)
DE (1) DE60210292T2 (ru)
EA (1) EA005773B1 (ru)
EE (1) EE05402B1 (ru)
ES (1) ES2261703T3 (ru)
HK (1) HK1069168A1 (ru)
HU (1) HU230155B1 (ru)
IL (2) IL159854A0 (ru)
MX (1) MXPA04000433A (ru)
NO (1) NO324257B1 (ru)
NZ (1) NZ530168A (ru)
PL (1) PL208291B1 (ru)
SK (1) SK287245B6 (ru)
WO (1) WO2003008406A1 (ru)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA200500673A1 (ru) * 2002-10-22 2005-12-29 Рэнбакси Лабораториз Лимитед Аморфная форма соли эзомепразола, способ ее получения и фармацевтическая композиция на её основе
US7683177B2 (en) 2003-06-10 2010-03-23 Teva Pharmaceutical Industries Ltd Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
WO2006019151A1 (ja) * 2004-08-20 2006-02-23 Eisai R & D Management Co., Ltd. ベンズイミダゾール誘導体の製造方法
WO2006049486A1 (en) * 2004-11-08 2006-05-11 Dishman Pharmaceuticals And Chemicals Ltd. A PREPARATION METHOD FOR SUBSTITUTED 2-(2-PYRIDYLMETHOYLSULPHINYL)-l-H-BENZIMID AZOLES
EP1681056A1 (en) 2005-01-14 2006-07-19 Krka Tovarna Zdravil, D.D., Novo Mesto Process for preparing lansoprazole
GB0525710D0 (en) * 2005-12-17 2006-01-25 Pliva Hrvatska D O O An improved process for preparing of substituted 2-benzimidazolesulfoxide compounds
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
EP1818331A1 (en) 2006-02-14 2007-08-15 EOS Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ti Caret A.S. Process for the preparation of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole substantially free of sulfone impurity
WO2007129328A2 (en) * 2006-05-09 2007-11-15 Cadila Healthcare Limited Process for preparing 2-[pyridinyl]sulfinyl-substituted benzimidazoles
WO2007138468A2 (en) * 2006-06-01 2007-12-06 Wockhardt Ltd Processes for the preparation of lansoprazole
WO2008017020A2 (en) * 2006-08-03 2008-02-07 Dr. Reddy's Laboratories Limited Process for preparing proton pump inhibitors
EP2069329A4 (en) * 2006-10-06 2010-04-07 Reddys Lab Ltd Dr PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND THEIR SALTS
EP1947099A1 (en) 2007-01-18 2008-07-23 LEK Pharmaceuticals D.D. Process for solvent removal from omeprazole salts
EA016297B1 (ru) * 2007-06-15 2012-03-30 Эмкьюр Фармасьютикалз Лимитед Способ сульфоксидирования биологически активных соединений
WO2008155780A2 (en) * 2007-06-21 2008-12-24 Matrix Laboratories Ltd Improved process for the preparation of pure rabeprazole
EP2022789A1 (en) * 2007-08-06 2009-02-11 Farmaprojects, S.A. Process for the preparation of a gastric acid secretion inhibitor
WO2009066317A2 (en) * 2007-08-20 2009-05-28 Macleods Pharmaceuticals Limited Process for the preparation of pantoprazole sodium
EP2030973A1 (en) * 2007-08-31 2009-03-04 KRKA, tovarna zdravil, d.d., Novo mesto Process for preparing 2-sulfinyl-1H-benzimidazoles
US8071781B2 (en) 2008-11-11 2011-12-06 Syn-Tech Chem. & Pharm. Co., Ltd. Process for preparing rabeprazole sodium
US9725500B2 (en) * 2010-03-02 2017-08-08 Seattle Genetics, Inc. Methods for screening antibodies
CN104418837A (zh) * 2013-08-19 2015-03-18 长沙市如虹医药科技有限公司 一种氧化硫醚成亚砜的方法
CN104402866A (zh) * 2014-11-07 2015-03-11 烟台万润精细化工股份有限公司 一种制备埃索美拉唑杂质j和k的方法
CN104402867A (zh) * 2014-11-07 2015-03-11 烟台万润精细化工股份有限公司 一种制备埃索美拉唑杂质h和b的方法
CN104530006B (zh) * 2015-01-06 2018-05-11 江苏奥赛康药业股份有限公司 兰索拉唑的制备方法
CN104744440B (zh) * 2015-03-12 2016-09-07 常州康丽制药有限公司 雷贝拉唑硫醚的回收方法
CN110487918B (zh) * 2018-05-14 2022-02-08 中国医学科学院药物研究所 泮托拉唑钠及其起始原料中基因毒性杂质的分析方法
CN109354587B (zh) * 2018-10-18 2020-09-18 成都天台山制药有限公司 泮托拉唑钠的制备方法和泮托拉唑钠

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9002043D0 (sv) * 1990-06-07 1990-06-07 Astra Ab Improved method for synthesis
NZ244301A (en) * 1991-09-20 1994-08-26 Merck & Co Inc Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds
KR960002912B1 (ko) * 1993-02-19 1996-02-28 영진약품공업주식회사 신규한 벤즈이미다졸 유도체
ES2094694B1 (es) 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
CN1053444C (zh) * 1996-03-20 2000-06-14 常州市第四制药厂 奥美拉唑的一种精制方法
SK283805B6 (sk) * 1996-09-09 2004-02-03 Slovakofarma, A. S. Spôsob prípravy omeprazolu
SI20019A (sl) 1998-07-13 2000-02-29 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola

Also Published As

Publication number Publication date
MXPA04000433A (es) 2004-03-18
PL367006A1 (en) 2005-02-07
CN1525970A (zh) 2004-09-01
CZ304526B6 (cs) 2014-06-18
EE200400052A (et) 2004-04-15
PL208291B1 (pl) 2011-04-29
ES2261703T3 (es) 2006-11-16
JP2005500333A (ja) 2005-01-06
IL159854A0 (en) 2004-06-20
NO324257B1 (no) 2007-09-17
EP1409478A1 (en) 2004-04-21
JP4320250B2 (ja) 2009-08-26
BR0211101B1 (pt) 2013-12-17
EA005773B1 (ru) 2005-06-30
EP1409478B1 (en) 2006-03-29
KR100914175B1 (ko) 2009-08-27
AU2002321204B2 (en) 2008-05-08
KR20040016877A (ko) 2004-02-25
SK287245B6 (sk) 2010-04-07
BR0211101A (pt) 2004-06-22
HUP0400610A2 (hu) 2004-08-30
NZ530168A (en) 2004-08-27
ATE321758T1 (de) 2006-04-15
WO2003008406A1 (en) 2003-01-30
IL159854A (en) 2008-11-03
DE60210292D1 (de) 2006-05-18
BRPI0211101B8 (pt) 2021-05-25
CA2450433C (en) 2010-05-25
CA2450433A1 (en) 2003-01-30
CZ2004208A3 (cs) 2005-03-16
NO20040074L (no) 2004-01-08
EE05402B1 (et) 2011-04-15
HUP0400610A3 (en) 2012-09-28
DE60210292T2 (de) 2006-12-07
EA200400185A1 (ru) 2004-06-24
HU230155B1 (hu) 2015-09-28
CN1235899C (zh) 2006-01-11
US6919459B2 (en) 2005-07-19
US20040209918A1 (en) 2004-10-21
SK922004A3 (en) 2004-08-03

Similar Documents

Publication Publication Date Title
HK1069168A1 (en) Improved process for preparing benzimidazole-type compounds
MXPA02011458A (es) Derivados de acilfenilurea, metodos para su produccion y uso de los mismos como farmacos.
MY125399A (en) Benzimidazole compound crystal.
CA2384283A1 (en) Process for preparing 4-trifluoromethylsulphinylpyrazole derivative
WO2002096457A3 (en) Stable liquid formulations of antibodies
EP0997461A4 (en) PROCESSES FOR THE PREPARATION OF PYRIDINIC DERIVATIVES
MX2009000080A (es) Derivados de bencimidazol como inhibidores selectivos de la bomba de acido.
HK1052137A1 (en) Stabilized ascorbic acid solutions.
RU2002113104A (ru) Способы стабилизации соединений на основе бензимидазола
PL371127A1 (en) 6-aminomorphinane derivatives, method for the production and use thereof
MXPA03006904A (es) Procesos para la produccion de 2-(2-piridilmetil) sulfinil - 1h - bencimidazoles sustituidos.
IL176915A0 (en) Cycloalkyl substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, method for the production thereof and their use as medicaments
NO20040604L (no) Trisykliske imidazolpyridiner
AU2002368496A1 (en) Process for the preparation of sulphinyl derivatives by oxidation of the corresponding sulfides
WO2004111029A3 (en) Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
AU2003208686A1 (en) Alkylammonium salts of omeprazole and esomeprazole
NO20054418L (no) Substituert benzoylureidopyridylpiperidin- og -pyrrolidinkarboksylsyrederivater, deres fremstilling og anvendelse
WO2009066321A3 (en) Process for optically active sulfoxide compounds
SE0302382D0 (sv) New salts II
ITMI20031813A1 (it) Procedimento per la preparazione di pantoprazolo e suoi sali.
CY1105987T1 (el) Παραγωγα πυριδινο-2-υλο-μεθυλαμινης για την θepαπεια της εξαρτησης απο τα οπιοειδη
DE60029493D1 (de) Neues verfahren zur herstellung von 1-phenyl-2-(2-pyridyl)ethanamin
NO20040423L (no) Salter av substituerte 1,2,3,4-tetrahydroisokinolin-2-karboksylsyrederivater.
RS20100110A (en) Process for preparing 4- trifluoromethylsulphinylpyrazole derivative
RS20100109A (en) Process for preparing 4-trifluoromethzlsulphinylpyrazole derivative

Legal Events

Date Code Title Description
PE Patent expired

Effective date: 20220708