HK1065537A1 - Isoxazoline derivatives as anti-depressants - Google Patents

Isoxazoline derivatives as anti-depressants

Info

Publication number
HK1065537A1
HK1065537A1 HK04108329.1A HK04108329A HK1065537A1 HK 1065537 A1 HK1065537 A1 HK 1065537A1 HK 04108329 A HK04108329 A HK 04108329A HK 1065537 A1 HK1065537 A1 HK 1065537A1
Authority
HK
Hong Kong
Prior art keywords
depressants
isoxazoline derivatives
isoxazoline
derivatives
Prior art date
Application number
HK04108329.1A
Other languages
English (en)
Inventor
Jose Ignacio Andres-Gil
Francisco Javier Fernandez-Gadea
Manuel Jesus Alcazar-Vaca
Jose Maria Cid-Nunez
Joaquin Pastor Fernandez
Antonius Adrianus Hendrikus Petrus Megens
Godelieve Irma Christin Heylen
Xavier Jean Michile Langlois
Margaretha Hendrica Maria Bakker
Thomas Horst Wolfgang Steckler
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1065537A1 publication Critical patent/HK1065537A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK04108329.1A 2001-02-21 2004-10-25 Isoxazoline derivatives as anti-depressants HK1065537A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01200611 2001-02-21
EP01201264 2001-04-05
PCT/EP2002/001567 WO2002066484A1 (en) 2001-02-21 2002-02-13 Isoxazoline derivatives as anti-depressants

Publications (1)

Publication Number Publication Date
HK1065537A1 true HK1065537A1 (en) 2005-02-25

Family

ID=26076836

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04108329.1A HK1065537A1 (en) 2001-02-21 2004-10-25 Isoxazoline derivatives as anti-depressants

Country Status (33)

Country Link
US (1) US7169786B2 (et)
EP (1) EP1368358B1 (et)
JP (1) JP3953424B2 (et)
KR (1) KR100848898B1 (et)
CN (1) CN100400540C (et)
AR (1) AR035685A1 (et)
AT (1) ATE337322T1 (et)
AU (1) AU2002244717B2 (et)
BG (1) BG107984A (et)
BR (1) BR0207433A (et)
CA (1) CA2437505C (et)
CY (1) CY1106448T1 (et)
CZ (1) CZ20032515A3 (et)
DE (1) DE60214138T2 (et)
DK (1) DK1368358T3 (et)
EA (1) EA006747B1 (et)
EE (1) EE200300398A (et)
EG (1) EG23929A (et)
ES (1) ES2271230T3 (et)
HK (1) HK1065537A1 (et)
HR (1) HRP20030647A2 (et)
HU (1) HUP0303270A3 (et)
IL (2) IL157470A0 (et)
MX (1) MXPA03007432A (et)
MY (1) MY137836A (et)
NO (1) NO20033700L (et)
NZ (1) NZ526741A (et)
PL (1) PL208593B1 (et)
PT (1) PT1368358E (et)
SI (1) SI1368358T1 (et)
SK (1) SK11612003A3 (et)
TW (1) TWI257392B (et)
WO (1) WO2002066484A1 (et)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203299D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel compounds
EP1492796B1 (en) * 2002-04-02 2007-09-05 Janssen Pharmaceutica N.V. Substituted amino isoxazoline derivatives and their use as anti-depressants.
AR040967A1 (es) * 2002-08-12 2005-04-27 Janssen Pharmaceutica Nv Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos
CA2494557C (en) * 2002-08-15 2011-10-18 Janssen Pharmaceutica N.V. Fused heterocyclic isoxazoline derivatives and their use as anti-depressants
WO2004018482A2 (en) * 2002-08-21 2004-03-04 Janssen Pharmaceutica N.V. C6- and c9-substituted chromeno[4, 3-c]isoxazoline derivatives and their use as anti-depressants
WO2004078715A1 (ja) * 2003-03-07 2004-09-16 Astellas Pharma Inc. 2,6-ジ置換スチリルを有する含窒素へテロ環誘導体
EP1944306A1 (en) * 2003-09-17 2008-07-16 Janssen Pharmaceutica, N.V. Fused heterocyclic compounds as serotonin receptor modulators
EA200801812A1 (ru) 2003-09-17 2009-06-30 Янссен Фармацевтика Н.В. Сопряженные гетероциклические соединения
ES2331144T3 (es) * 2004-11-26 2009-12-22 Janssen Pharmaceutica Nv Derivados de isoxazolina-indol con actividad antipsicotica y ansiolitica mejorada.
AU2008226649B2 (en) * 2007-03-09 2013-08-01 Sanofi Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof
JP2010529144A (ja) * 2007-06-08 2010-08-26 ヘリコン・セラピューティクス・インコーポレーテッド 治療用ピラゾロキノリン尿素誘導体
WO2009082268A2 (ru) 2007-12-21 2009-07-02 Alla Chem, Llc ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ
AR078171A1 (es) 2009-09-15 2011-10-19 Sanofi Aventis Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0361577B1 (en) * 1988-09-19 1993-05-05 Akzo N.V. Tetrahydronaphthalene and indane derivatives
US5880121A (en) * 1996-01-05 1999-03-09 Hoechst Marion Roussel Inc. 4,5-dihydronaphth (1,2-c) isoxazoles and derivatives thereof
NZ329954A (en) * 1996-04-12 1999-07-29 Janssen Pharmaceutica Nv Isoxazolidine tetracyclic and tricyclic ring system derivatives and medicaments
HUP9602763A3 (en) * 1996-10-09 1999-05-28 Egyt Gyogyszervegyeszeti Gyar 3-phenyl isoxazole derivatives, process for producing them and pharmaceutical compositions containing the same
ATE259803T1 (de) * 1998-10-09 2004-03-15 Janssen Pharmaceutica Nv 4,5-dehydroisoxazole derivate und ihre pharmazeutische verwendung

Also Published As

Publication number Publication date
PL363264A1 (en) 2004-11-15
EE200300398A (et) 2003-12-15
NO20033700D0 (no) 2003-08-20
SI1368358T1 (sl) 2007-02-28
BR0207433A (pt) 2004-06-01
AR035685A1 (es) 2004-06-23
CA2437505A1 (en) 2002-08-29
NZ526741A (en) 2004-04-30
EP1368358A1 (en) 2003-12-10
DK1368358T3 (da) 2007-01-02
SK11612003A3 (sk) 2004-04-06
IL157470A (en) 2008-07-08
IL157470A0 (en) 2004-03-28
KR100848898B1 (ko) 2008-07-29
JP3953424B2 (ja) 2007-08-08
EP1368358B1 (en) 2006-08-23
EG23929A (en) 2008-01-14
ES2271230T3 (es) 2007-04-16
CZ20032515A3 (cs) 2003-12-17
AU2002244717B2 (en) 2007-07-19
HRP20030647A2 (en) 2005-06-30
CN1492871A (zh) 2004-04-28
MXPA03007432A (es) 2003-11-18
ATE337322T1 (de) 2006-09-15
EA006747B1 (ru) 2006-04-28
JP2004518748A (ja) 2004-06-24
NO20033700L (no) 2003-10-21
DE60214138D1 (de) 2006-10-05
CN100400540C (zh) 2008-07-09
TWI257392B (en) 2006-07-01
HUP0303270A2 (hu) 2004-01-28
KR20030076590A (ko) 2003-09-26
US7169786B2 (en) 2007-01-30
PT1368358E (pt) 2007-01-31
CY1106448T1 (el) 2011-10-12
BG107984A (bg) 2004-09-30
HUP0303270A3 (en) 2007-03-28
EA200300915A1 (ru) 2004-06-24
CA2437505C (en) 2010-02-09
PL208593B1 (pl) 2011-05-31
MY137836A (en) 2009-03-31
DE60214138T2 (de) 2007-03-29
WO2002066484A1 (en) 2002-08-29
US20040122037A1 (en) 2004-06-24

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130213