GT201200202A - Aminopirimidinas como inhibidores de syk - Google Patents

Aminopirimidinas como inhibidores de syk

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Publication number
GT201200202A
GT201200202A GT201200202A GT201200202A GT201200202A GT 201200202 A GT201200202 A GT 201200202A GT 201200202 A GT201200202 A GT 201200202A GT 201200202 A GT201200202 A GT 201200202A GT 201200202 A GT201200202 A GT 201200202A
Authority
GT
Guatemala
Prior art keywords
aminopirimidins
syk inhibitors
syk
inhibitors
aminopirimidines
Prior art date
Application number
GT201200202A
Other languages
English (en)
Inventor
Michael D Altman
Brian M Andresen
Kenneth L Arrington
Childers Kaleen Konrad
Di Francesco Maria Emilia
Donofrio Anthony
Ellis John Michael
Fischer Christian
Guerin David Joseph
Andrew M Haidle
Kattar Solomon
Knowles Sandra Lee
Li Chaomin
Lim Jongwon
Michelle R Machacek
Alan B Northrup
Brendan M O'boyle
Ryan D Otte
Petrocchi Alessia
Michael H Reutershan
Romeo Eric
Siu Tony
Brandon M Taoka
Trotter B Wesley
Zhou Hua
Burch Jason
Cote Bernard
Dupont-Gaudet Kristina
Fournier Jean-François
Gauthier Jacques Yves
Guay Daniel
Joel S Robichaud
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43502894&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GT201200202(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of GT201200202A publication Critical patent/GT201200202A/es

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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
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Abstract

LA PRESENTE INVENCIÓN PROPORCIONA NUEVAS AMINOPIRIMIDINAS LAS CUALES SON INHIBIDORAS DE TIROSINA QUINASA DEL BAZO (SYK) Y LA CUAL ES UNA PROTEÍNA TIROSINA QUINASA QUE SE HA DESCRITO COMO UN MEDIADOR CLAVE DE LA SEÑALIZACIÓN DE INMUNO-RECEPTORES POR LO QUE SON DE UTILIDAD EN CUADROS DE ASMA, COPD Y ARTRITIS REUMATOIDE
GT201200202A 2009-12-17 2012-06-15 Aminopirimidinas como inhibidores de syk GT201200202A (es)

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Application Number Priority Date Filing Date Title
US28726709P 2009-12-17 2009-12-17

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GT201200202A true GT201200202A (es) 2014-10-13

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US (3) US8759366B2 (es)
EP (1) EP2513098B1 (es)
JP (2) JP5242857B2 (es)
KR (1) KR101445012B1 (es)
CN (1) CN102858767B (es)
AR (1) AR080672A1 (es)
AU (1) AU2010331927B2 (es)
BR (1) BR112012014703B1 (es)
CA (1) CA2782889C (es)
CL (1) CL2012001627A1 (es)
CO (1) CO6551728A2 (es)
CR (1) CR20120331A (es)
DO (1) DOP2012000166A (es)
EA (1) EA022790B1 (es)
EC (1) ECSP12011982A (es)
ES (1) ES2609040T3 (es)
GE (1) GEP20146125B (es)
GT (1) GT201200202A (es)
MA (1) MA33926B1 (es)
MX (1) MX2012007154A (es)
NI (1) NI201200108A (es)
NZ (1) NZ600673A (es)
PE (1) PE20121480A1 (es)
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TN (1) TN2012000288A1 (es)
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Families Citing this family (79)

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Publication number Priority date Publication date Assignee Title
PE20121480A1 (es) 2009-12-17 2012-11-10 Merck Sharp & Dohme Aminopirimidinas como inhibidores de syk
US8735417B2 (en) 2009-12-17 2014-05-27 Merck Sharp & Dohme Corp. Aminopyrimidines as Syk inhibitors
GEP20156243B (en) 2009-12-23 2015-02-10 Takeda Pharmaceutical Fused heteroaromatic pyrrolidinones as syk inhibitors
NZ601143A (en) 2010-01-12 2014-10-31 Ab Science Thiazole and oxazole kinase inhibitors
US8754114B2 (en) 2010-12-22 2014-06-17 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
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