BR112013007441A2 - produção de alfa-olefinas usando sintases de policetídeo - Google Patents

produção de alfa-olefinas usando sintases de policetídeo

Info

Publication number
BR112013007441A2
BR112013007441A2 BR112013007441A BR112013007441A BR112013007441A2 BR 112013007441 A2 BR112013007441 A2 BR 112013007441A2 BR 112013007441 A BR112013007441 A BR 112013007441A BR 112013007441 A BR112013007441 A BR 112013007441A BR 112013007441 A2 BR112013007441 A2 BR 112013007441A2
Authority
BR
Brazil
Prior art keywords
alpha olefin
olefin production
polyketide synthases
olefin
polyketide
Prior art date
Application number
BR112013007441A
Other languages
English (en)
Inventor
J Steen Eric
D Keasling Jay
L Fortman Jeffrey
Katz Leonard
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of BR112013007441A2 publication Critical patent/BR112013007441A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/002—Preparation of hydrocarbons or halogenated hydrocarbons cyclic
    • C12P5/005—Preparation of hydrocarbons or halogenated hydrocarbons cyclic aromatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)

Abstract

produção de alfa-olefinas usando sintases de policetídeo. a presente invenção refere-se a uma sintase de policetídeo (pks) capaz de sintetizar uma <244>-olefina, tal como 1-hexano ou butadieno. a presente invenção também refere-se a uma célula hospedeira que compreende pks e quando cultivado produz <244>-olefina.
BR112013007441A 2010-09-28 2011-09-28 produção de alfa-olefinas usando sintases de policetídeo BR112013007441A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38743510P 2010-09-28 2010-09-28
PCT/US2011/053787 WO2012050931A2 (en) 2010-09-28 2011-09-28 Producing alpha-olefins using polyketide synthases

Publications (1)

Publication Number Publication Date
BR112013007441A2 true BR112013007441A2 (pt) 2017-07-04

Family

ID=45938883

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013007441A BR112013007441A2 (pt) 2010-09-28 2011-09-28 produção de alfa-olefinas usando sintases de policetídeo

Country Status (11)

Country Link
US (2) US20130267696A1 (pt)
EP (1) EP2622085A4 (pt)
JP (1) JP2013544500A (pt)
KR (1) KR20130123388A (pt)
CN (1) CN103249837A (pt)
AU (1) AU2011314084B2 (pt)
BR (1) BR112013007441A2 (pt)
CA (1) CA2812763A1 (pt)
MX (1) MX2013003439A (pt)
SG (2) SG10201508018SA (pt)
WO (1) WO2012050931A2 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
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MX2012000170A (es) 2009-06-22 2012-05-23 Joule Unltd Technologies Inc Biositesis de 1-alquenos en microorganismos de ingenieria.
US20120107894A1 (en) * 2010-10-28 2012-05-03 Joule Unlimited Technologies, Inc. Methods and Compositions for the Recombinant Biosynthesis of Terminal Olefins
JP6010343B2 (ja) * 2012-05-21 2016-10-19 株式会社ブリヂストン イソプレン−ブタジエン共重合体、イソプレン−ブタジエン共重合体の製造方法、ゴム組成物及びタイヤ
JP6010342B2 (ja) * 2012-05-21 2016-10-19 株式会社ブリヂストン イソプレン−ブタジエン共重合体、イソプレン−ブタジエン共重合体の製造方法、ゴム組成物及びタイヤ
JP6074161B2 (ja) * 2012-05-22 2017-02-01 株式会社ブリヂストン ゴム組成物およびタイヤの製造方法
JP6074160B2 (ja) * 2012-05-22 2017-02-01 株式会社ブリヂストン ゴム組成物およびタイヤの製造方法
KR20150040359A (ko) 2012-08-10 2015-04-14 오피엑스 바이오테크놀로지스, 인크. 지방산 및 지방산 유도된 산물의 생산을 위한 미생물 및 방법
JP5536840B2 (ja) 2012-09-07 2014-07-02 住友ゴム工業株式会社 タイヤ用ゴム組成物、タイヤ部材、及び空気入りタイヤ
US20150057465A1 (en) 2013-03-15 2015-02-26 Opx Biotechnologies, Inc. Control of growth-induction-production phases
WO2014207113A1 (en) 2013-06-26 2014-12-31 Abengoa Bioenergia Nuevas Tecnologias S.A. Yeasts engineered for the production of valuable chemicals from sugars
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
CN106795483A (zh) 2013-07-19 2017-05-31 嘉吉公司 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法
US10233431B2 (en) 2014-02-26 2019-03-19 The Regents Of The University Of California Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases
JP6532192B2 (ja) * 2014-04-24 2019-06-19 住友ゴム工業株式会社 タイヤ用ゴム組成物、タイヤ部材、及び空気入りタイヤ
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
WO2017011407A2 (en) * 2015-07-10 2017-01-19 The Regents Of The University Of California Producing adipic acid and related compounds using hybrid polyketide synthases
CN105176942A (zh) * 2015-08-04 2015-12-23 北京农学院 来源于树莓的聚酮合酶RinPKS1及其相关生物材料与应用
JP2020506702A (ja) 2017-02-02 2020-03-05 カーギル インコーポレイテッド Ｃ６−ｃ１０脂肪酸誘導体を生成する遺伝子組み換え細胞
CA3097110A1 (en) 2018-01-30 2019-08-08 Inolex Investment Corporation Natural 1,2-alkanediols, compositions having natural 1,2-alkanediols and processes for making the same
US11884620B2 (en) 2020-12-11 2024-01-30 The Regents Of The University Of California Use of polyamines in the pretreatment of biomass

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6558942B1 (en) * 1994-05-06 2003-05-06 The Leland Stanford Junior University Combinatorial polyketide libraries produced using a modular PKS gene cluster as scaffold
US6410301B1 (en) * 1998-11-20 2002-06-25 Kosan Biosciences, Inc. Myxococcus host cells for the production of epothilones
US6998256B2 (en) * 2000-04-28 2006-02-14 Kosan Biosciences, Inc. Methods of obtaining epothilone D using crystallization and /or by the culture of cells in the presence of methyl oleate
EP1307579A2 (en) * 2000-08-09 2003-05-07 Kosan Biosciences, Inc. Bio-intermediates for use in the chemical synthesis of polyketides
AU1981802A (en) * 2000-11-20 2002-06-03 Cargill Inc 3-hydroxypropionic acid and other organic compounds
US20050227316A1 (en) * 2004-04-07 2005-10-13 Kosan Biosciences, Inc. Synthetic genes
JP2011516045A (ja) * 2008-03-28 2011-05-26 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ポリケチドシンターゼを使用するジカルボン酸の生成法
JP2011519860A (ja) * 2008-04-29 2011-07-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ポリケチドシンターゼを使用するバイオ燃料の生成
MX2012000170A (es) * 2009-06-22 2012-05-23 Joule Unltd Technologies Inc Biositesis de 1-alquenos en microorganismos de ingenieria.
US8765431B2 (en) * 2009-07-23 2014-07-01 The Regents Of The University Of Michigan Method for enzymatic production of decarboxylated polyketides and fatty acids

Also Published As

Publication number Publication date
KR20130123388A (ko) 2013-11-12
SG10201508018SA (en) 2015-11-27
CN103249837A (zh) 2013-08-14
WO2012050931A2 (en) 2012-04-19
MX2013003439A (es) 2013-07-17
US20160068827A1 (en) 2016-03-10
US20130267696A1 (en) 2013-10-10
AU2011314084B2 (en) 2016-06-02
CA2812763A1 (en) 2012-04-19
JP2013544500A (ja) 2013-12-19
EP2622085A2 (en) 2013-08-07
US9856461B2 (en) 2018-01-02
SG188654A1 (en) 2013-04-30
EP2622085A4 (en) 2014-04-02
AU2011314084A1 (en) 2013-05-02
WO2012050931A3 (en) 2012-06-21

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2481 DE 24-07-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.